| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xingyu Nan, Xingkun Jin, Yu Song, Kaimin Zhou, Yukai Qin, Qun Wang, Weiwei L. Effect of polystyrene nanoplastics on cell apoptosis, glucose metabolism, and antibacterial immunity of Eriocheir sinensis. Environmental pollution (Barking, Essex : 1987). 2022-08-16. PMID:35973454. |
this study aimed to investigate the effects of ps nps on apoptosis and glucose metabolism in chinese mitten crabs, and whether ps nps could synergistically affect the antibacterial immunity of crabs. |
2022-08-16 |
2023-08-14 |
Not clear |
| Xingyu Nan, Xingkun Jin, Yu Song, Kaimin Zhou, Yukai Qin, Qun Wang, Weiwei L. Effect of polystyrene nanoplastics on cell apoptosis, glucose metabolism, and antibacterial immunity of Eriocheir sinensis. Environmental pollution (Barking, Essex : 1987). 2022-08-16. PMID:35973454. |
the rna sequencing data showed that after hemocytes endocytosed nps, apoptosis and glucose metabolism-related gene expression was significantly induced, resulting in abnormal cell apoptosis and a glucose metabolism disorder. |
2022-08-16 |
2023-08-14 |
Not clear |
| Xingyu Nan, Xingkun Jin, Yu Song, Kaimin Zhou, Yukai Qin, Qun Wang, Weiwei L. Effect of polystyrene nanoplastics on cell apoptosis, glucose metabolism, and antibacterial immunity of Eriocheir sinensis. Environmental pollution (Barking, Essex : 1987). 2022-08-16. PMID:35973454. |
in summary, nps could be endocytosed by crab hemocytes, which adversely affected the cell apoptosis, glucose metabolism, and antibacterial immunity of eriocheir sinensis. |
2022-08-16 |
2023-08-14 |
Not clear |
| Sayanta Dutta, Pratik Chakraborty, Susmita Basak, Sumit Ghosh, Noyel Ghosh, Sharmistha Chatterjee, Saikat Dewanjee, Parames C Si. Synthesis, characterization, and evaluation of in vitro cytotoxicity and in vivo antitumor activity of asiatic acid-loaded poly lactic-co-glycolic acid nanoparticles: A strategy of treating breast cancer. Life sciences. 2022-08-12. PMID:35961595. |
immunoblotting showed that aa-plga nps elicited an intrinsic pathway of apoptosis in mcf-7 cells. |
2022-08-12 |
2023-08-14 |
mouse |
| Madhu Gupta, Vikas Sharma, Kalicharan Sharma, Anoop Kumar, Ajay Sharma, Imran Kazmi, Fahad A Al-Abbasi, Sami I Alzarea, Obaid Afzal, Abdulmalik Saleh Alfawaz Altamimi, Sachin Kumar Singh, Gaurav Gupta, Keshav Raj Paudel, Philip M Hansbro, Kamal Du. A kNGR Peptide-Tethered Lipid-Polymer Hybrid Nanocarrier-Based Synergistic Approach for Effective Tumor Therapy: Development, Characterization, Ex-Vivo, and In-Vivo Assessment. Pharmaceutics. vol 14. issue 7. 2022-07-27. PMID:35890297. |
the results support that, compared to other nps, plns-kngr-nps are highly cytotoxic, owing to higher apoptosis and intracellular uptake. |
2022-07-27 |
2023-08-14 |
mouse |
| Jiacui Liu, Ping Wang, Ben Huang, Qingyuan Cheng, Yiping Duan, Liangyue Chen, Tiantian Ma, Cuiwen Zhu, Dongxu Li, Wei Fan, Mingxia Y. Effective suppression of triple negative breast cancer by paclitaxel nanoparticles conjugated with transmembrane TNF-α monoclonal antibody. International journal of pharmaceutics. 2022-07-08. PMID:35803533. |
tmtnf-α mab-ptx nps exerts anti-tumor effects via promoting apoptosis and regulating mitogen-activated protein kinase (mapk), phosphatidylinositol 3-kinase (pi3k) / protein kinase b (akt)/ mammalian target of rapamycin (mtor) cascade, as well as amp-activated protein kinase (ampk) and nuclear factor kappa-b (nf-κb) pathways. |
2022-07-08 |
2023-08-14 |
mouse |
| Ehab Tousson, Sarah Alashmouni, Afaf El-Atrash, Doaa M El-Gharbaw. The potential curative role of Avena sativa extract against oxidative stress, DNA damage and apoptosis induced by acute hepatotoxicity of silver nanoparticles in rats. Environmental toxicology. 2022-06-29. PMID:35765203. |
the goal of this study was to investigate if avena sativa (avs) extract could ameliorate ag nps toxicity-induced alterations in liver structure and function, dna damage, apoptosis, and oxidative stress. |
2022-06-29 |
2023-08-14 |
rat |
| Zhuojia Xu, Aihua Qu, Hongyu Zhang, Weiwei Wang, Changlong Hao, Meiru Lu, Baimei Shi, Liguang Xu, Maozhong Sun, Chuanlai Xu, Hua Kuan. Photoinduced elimination of senescent microglia cells Chemical science. vol 13. issue 22. 2022-06-27. PMID:35756519. |
in this study, chiral gold nanoparticles (nps) with different helical directions were synthesized to selectively induce the apoptosis of senescent cells under light illumination. |
2022-06-27 |
2023-08-14 |
Not clear |
| G Basini, S Bussolati, L Andriani, S Grolli, S Bertini, T Iemmi, A Menozzi, F Quintavalla, R Ramoni, P Serventi, F Grassell. The effects of nanoplastics on adipose stromal cells from swine tissues. Domestic animal endocrinology. vol 81. 2022-06-21. PMID:35728298. |
in organisms, nps can cross biological membranes, and cause oxidative stress, cell damage, apoptosis, and endocrine interference. |
2022-06-21 |
2023-08-14 |
Not clear |
| Wali Muhammad, Jiaqi Zhu, Zihe Zhai, Jieqi Xie, Jiahang Zhou, Xudong Feng, Bing Feng, Qiaoling Pan, Shifen Li, Rajiu Venkatesan, Pan Li, Hongcui Cao, Changyou Ga. ROS-responsive polymer nanoparticles with enhanced loading of dexamethasone effectively modulate the lung injury microenvironment. Acta biomaterialia. 2022-06-20. PMID:35724918. |
the delivery of pftu@dex nps decreased the proportion of neutrophils significantly, mitigated the cell apoptosis remarkably compared to the other groups, reduced m1 macrophages and increased m2 macrophages in vivo. |
2022-06-20 |
2023-08-14 |
mouse |
| Wali Muhammad, Jiaqi Zhu, Zihe Zhai, Jieqi Xie, Jiahang Zhou, Xudong Feng, Bing Feng, Qiaoling Pan, Shifen Li, Rajiu Venkatesan, Pan Li, Hongcui Cao, Changyou Ga. ROS-responsive polymer nanoparticles with enhanced loading of dexamethasone effectively modulate the lung injury microenvironment. Acta biomaterialia. 2022-06-20. PMID:35724918. |
therefore, the pftu@dex nps could efficiently suppress inflammatory cells, ros signaling pathways, and cell apoptosis to ameliorate lps-induced ali. |
2022-06-20 |
2023-08-14 |
mouse |
| Yan Xu, Jingqi Qi, Wei Sun, Wu Zhong, Hongwei W. Therapeutic Effects of Zoledronic Acid-Loaded Hyaluronic Acid/Polyethylene Glycol/Nano-Hydroxyapatite Nanoparticles on Osteosarcoma. Frontiers in bioengineering and biotechnology. vol 10. 2022-06-13. PMID:35694235. |
the nps significantly enhanced the apoptosis-related protein expression and tumor cell apoptosis rate. |
2022-06-13 |
2023-08-14 |
mouse |
| Yan Xu, Jingqi Qi, Wei Sun, Wu Zhong, Hongwei W. Therapeutic Effects of Zoledronic Acid-Loaded Hyaluronic Acid/Polyethylene Glycol/Nano-Hydroxyapatite Nanoparticles on Osteosarcoma. Frontiers in bioengineering and biotechnology. vol 10. 2022-06-13. PMID:35694235. |
in the orthotopic osteosarcoma nude mice model, local injection of the ha-peg-nha-zol nps stimulated tumor necrosis, apoptosis, and granulocyte infiltration in the blood vessels. |
2022-06-13 |
2023-08-14 |
mouse |
| Hui Ming, Bowen Li, Hailong Tian, Li Zhou, Jingwen Jiang, Tingting Zhang, Ling Qiao, Peijie Wu, Edouard C Nice, Wei Zhang, Weifeng He, Canhua Huang, Haiyuan Zhan. A minimalist and robust chemo-photothermal nanoplatform capable of augmenting autophagy-modulated immune response against breast cancer. Materials today. Bio. vol 15. 2022-05-31. PMID:35634171. |
the ic/ir820 nps show an enhanced therapeutic effect on breast cancer by inducing reactive oxygen species (ros)-mediated apoptosis and autophagic death. |
2022-05-31 |
2023-08-13 |
mouse |
| Suliman A Alsagab. Transcriptomics-Based Investigation of Molecular Mechanisms Underlying Apoptosis Induced by ZnO Nanoparticles in Human Diffuse Large B-Cell Lymphoma. International journal of nanomedicine. vol 17. 2022-05-25. PMID:35611214. |
this study was set to assess the potential of zno nps to selectively induce apoptosis in human dlbcl cells (oci-ly3), and to describe possible molecular mechanisms of action. |
2022-05-25 |
2023-08-13 |
human |
| Yihan Wu, Jingjing Li, Xuemei Zhong, Jinfeng Shi, Yanfen Cheng, Chenglin He, Jiaxin Li, Liang Zou, Chaomei Fu, Meiwan Chen, Jinming Zhang, Huile Ga. A pH-sensitive supramolecular nanosystem with chlorin e6 and triptolide co-delivery for chemo-photodynamic combination therapy. Asian journal of pharmaceutical sciences. vol 17. issue 2. 2022-05-18. PMID:35582637. |
in view of the combination benefit of photodynamic therapy and chemotherapy, as well as co-encapsulation in the fabricated ph-sensitive supramolecular nps, tpl+ce6/nps exhibited significant efficacy to suppress cellular proliferation, boost ros level, lower mmp, and promote cellular apoptosis |
2022-05-18 |
2023-08-13 |
Not clear |
| Tapan Behl, Piyush Madaan, Aayush Sehgal, Sukhbir Singh, Hafiz A Makeen, Mohammed Albratty, Hassan A Alhazmi, Abdulkarim M Meraya, Simona Bunga. Demystifying the Neuroprotective Role of Neuropeptides in Parkinson's Disease: A Newfangled and Eloquent Therapeutic Perspective. International journal of molecular sciences. vol 23. issue 9. 2022-05-14. PMID:35562956. |
numerous nps, for instance, substance p (sp), ghrelin, neuropeptide y (npy), neurotensin, pituitary adenylate cyclase-activating polypeptide (pacap), nesfatin-1, and somatostatin, have been displayed to exhibit consequential neuroprotection in both in vivo and in vitro pd models via suppressing apoptosis, cytotoxicity, oxidative stress, inflammation, autophagy, neuronal toxicity, microglia stimulation, attenuating disease-associated manifestations, and stimulating chondriosomal bioenergetics. |
2022-05-14 |
2023-08-13 |
human |
| Wenwen Mu, Qi Wang, Mingxia Jia, Sijia Dong, Sijie Li, Jie Yang, Guoyun Li. Hepatoprotective Effects of Albumin-Encapsulated Nanoparticles of a Curcumin Derivative COP-22 against Lipopolysaccharide/D-Galactosamine-Induced Acute Liver Injury in Mice. International journal of molecular sciences. vol 23. issue 9. 2022-05-14. PMID:35563293. |
the anti-inflammatory activity of 22 nps is related to the regulation of the nf-κb signaling pathways; the antioxidant activity is related to the regulation of the nrf2 signaling pathways; and the apoptosis activity is related to mitochondrial pathways, involving bcl-2 family and caspase-3 protein. |
2022-05-14 |
2023-08-13 |
mouse |
| Xueling Yin, Siyi Ran, Haoyan Cheng, Meng Zhang, Wei Sun, Ying Wan, Chunsheng Shao, Zhihong Zh. Polydopamine-modified ZIF-8 nanoparticles as a drug carrier for combined chemo-photothermal osteosarcoma therapy. Colloids and surfaces. B, Biointerfaces. vol 216. 2022-05-06. PMID:35523102. |
biology assays in vitro indicated that the pda/mtx@zif-8 nps were able to efficiently induce mg63 cell apoptosis through reducing mitochondrial membrane potentials (mmps), and the introduction of photothermal agents enhanced the antitumor effect and decreased the dose of chemotherapeutic drugs. |
2022-05-06 |
2023-08-13 |
Not clear |
| Jing Zheng, Yixuan Sun, Tengfei Long, Dong Yuan, Song Yue, Ni Zhang, Zhu Yan. Sonosensitizer nanoplatform-mediated sonodynamic therapy induced immunogenic cell death and tumor immune microenvironment variation. Drug delivery. vol 29. issue 1. 2022-04-08. PMID:35393920. |
the antitumor effect of nps triggered by ultrasound (us) was measured by an apoptosis assay in a c57/bl6 mouse model. |
2022-04-08 |
2023-08-13 |
mouse |