| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Parvin Ghasemi, Gholamreza Shafiee, Nasrin Ziamajidi, Roghayeh Abbasalipourkabi. Copper Nanoparticles Induce Apoptosis and Oxidative Stress in SW480 Human Colon Cancer Cell Line. Biological trace element research. 2022-10-24. PMID:36274109. |
as the effect of cunps on the induction of oxidative stress and apoptosis in the human colorectal cancer cell line sw480 has not yet been studied, we investigated the toxicity and mechanism of action of these nps in sw480 cells. |
2022-10-24 |
2023-08-14 |
human |
| Parvin Ghasemi, Gholamreza Shafiee, Nasrin Ziamajidi, Roghayeh Abbasalipourkabi. Copper Nanoparticles Induce Apoptosis and Oxidative Stress in SW480 Human Colon Cancer Cell Line. Biological trace element research. 2022-10-24. PMID:36274109. |
to investigate the effect of nps on cellular apoptosis, hoechst33258 staining was performed, and the expression of bax, bcl-2, and p53 was evaluated by qrt-pcr. |
2022-10-24 |
2023-08-14 |
human |
| Yunrong Yang, Min Liu, Tianjiao Zhao, Qiaohui Chen, Yuqi Yang, Shuya Wang, Jinping Zhang, Guiming Deng, Kewei Sun, Yayun Nan, Ke Cao, Kelong Ai, Qiong Huan. Epigallocatechin-3-gallate Mo nanoparticles (EGM NPs) efficiently treat liver injury by strongly reducing oxidative stress, inflammation and endoplasmic reticulum stress. Frontiers in pharmacology. vol 13. 2022-10-24. PMID:36278211. |
egm nps effectively scavenged various ros and reduced cell apoptosis at the cellular level. |
2022-10-24 |
2023-08-14 |
Not clear |
| Juncan Li, Ming Yuan, Tong Qiu, Mengli Lu, Siwen Zhan, Yuting Bai, Mengjia Yang, Xia Liu, Xueqiong Zhan. A glutathione -sensitive drug delivery system based on carboxymethyl chitosan co-deliver Rose Bengal and oxymatrine for combined cancer treatment. Journal of biomaterials science. Polymer edition. 2022-10-22. PMID:36272104. |
furthermore, omt/cmcs-cys-rb nps could inhibit the pi3k/akt signaling pathway in oxidative stress, and realize tumor apoptosis through mitochondria-related pathways. |
2022-10-22 |
2023-08-14 |
Not clear |
| Wenwan Shi, Xia Cao, Qi Liu, Qin Zhu, Kai Liu, Tianwen Deng, Qingtong Yu, Wenwen Deng, Jiangnan Yu, Qilong Wang, Ximing X. Hybrid Membrane-Derived Nanoparticles for Isoliquiritin Enhanced Glioma Therapy. Pharmaceuticals (Basel, Switzerland). vol 15. issue 9. 2022-09-23. PMID:36145280. |
we also investigated the mechanism of the antitumor effect of isl@hm nps, which revealed a marked inhibition of tumor cell proliferation and promotion of senescence and apoptosis of tumor cells of the formulation. |
2022-09-23 |
2023-08-14 |
human |
| Courtney van Ballegooie, Nicole Wretham, Tanya Ren, Ioana-Mihaela Popescu, Donald T Yapp, Marcel B Ball. PEG Conjugated Zein Nanoparticles for In Vivo Use. Pharmaceutics. vol 14. issue 9. 2022-09-23. PMID:36145579. |
when the nps were cultured with cells for 72 h, no cytotoxicity or early signs of apoptosis were identified. |
2022-09-23 |
2023-08-14 |
mouse |
| Mengwei Wang, Ping Zhang, Zeyu Li, Yu Yan, Xin Cheng, Guang Wang, Xuesong Yan. Different cellular mechanisms from low- and high-dose zinc oxide nanoparticles-induced heart tube malformation during embryogenesis. Nanotoxicology. 2022-09-22. PMID:36137004. |
during early cardiogenesis, zno nps exposure increased the chance of heart tube malformation, while precardiac cell apoptosis rises in the phenotype of closure defect and bifida. |
2022-09-22 |
2023-08-14 |
human |
| Mengwei Wang, Ping Zhang, Zeyu Li, Yu Yan, Xin Cheng, Guang Wang, Xuesong Yan. Different cellular mechanisms from low- and high-dose zinc oxide nanoparticles-induced heart tube malformation during embryogenesis. Nanotoxicology. 2022-09-22. PMID:36137004. |
apart from cell apoptosis, high-dose zno nps exposure led to massive programmed necrosis, and further experiments verified that ferroptosis remained primarily in zno nps-induced programmed necrosis. |
2022-09-22 |
2023-08-14 |
human |
| Liying Dong, Shutao Wang, Lin Zhang, Dongmei Liu, Hong Yo. DBDPE and ZnO NPs synergistically induce neurotoxicity of SK-N-SH cells and activate mitochondrial apoptosis signaling pathway and Nrf2-mediated antioxidant pathway. Journal of hazardous materials. vol 441. 2022-09-09. PMID:36084461. |
dbdpe and zno nps synergistically induce neurotoxicity of sk-n-sh cells and activate mitochondrial apoptosis signaling pathway and nrf2-mediated antioxidant pathway. |
2022-09-09 |
2023-08-14 |
human |
| Liying Dong, Shutao Wang, Lin Zhang, Dongmei Liu, Hong Yo. DBDPE and ZnO NPs synergistically induce neurotoxicity of SK-N-SH cells and activate mitochondrial apoptosis signaling pathway and Nrf2-mediated antioxidant pathway. Journal of hazardous materials. vol 441. 2022-09-09. PMID:36084461. |
moreover, dbdpe and zno nps caused apoptosis by disrupting mitochondrial kinetic homeostasis, reducing mitochondrial membrane potential (mmp), increasing cytochrome c release and regulating bax/bcl-2 and caspase-3 mrna and protein expression. |
2022-09-09 |
2023-08-14 |
human |
| Armina Shirangi, Fatemeh Mottaghitalab, Sajad Dinarvand, Fatemeh Atyab. Theranostic silk sericin/SPION nanoparticles for targeted delivery of ROR1 siRNA: Synthesis, characterization, diagnosis and anticancer effect on triple-negative breast cancer. International journal of biological macromolecules. 2022-09-09. PMID:36084874. |
the apoptosis study showed significant death of mda-mb-231 cells after 24 h treatment with the prepared nps. |
2022-09-09 |
2023-08-14 |
mouse |
| Jiangnan Yi, Yuanliang Li, Qianying Mai, Yaxuan Li, Yingying Lin, Xiaoshan Weng, Zhu Ai, Mingze Li, Peng Shang, Mujahid Iqbal, Khalid Mehmood, Yung-Fu Chang, Zhaoxin Tang, Hui Zhang, Ying L. Hepatotoxicity and the role of the gut-liver axis in dogs after oral administration of zinc oxide nanoparticles. Metallomics : integrated biometal science. 2022-09-04. PMID:36057841. |
results showed that zno nps significantly inhibited the hepatocyte apoptosis via cytc pathway and promoted the autophagy via activating mtor/atg5 pathway. |
2022-09-04 |
2023-08-14 |
Not clear |
| Liyao Zhang, Peijie Huang, Shubin Huang, Tao Wang, Shufeng Chen, Zhihao Chen, Yi Zhou, Linghao Qi. Development of ligand modified erythrocyte coated polydopamine nanomedicine to codeliver chemotherapeutic agent and oxygen for chemo-photothermal synergistic cancer therapy. International journal of pharmaceutics. 2022-09-04. PMID:36058410. |
moreover, dppr nps could be effectively internalized into tumor cells and destroyed the intracellular redox balance to mediate cell apoptosis. |
2022-09-04 |
2023-08-14 |
Not clear |
| Jiang Ni, Yuanyuan Mi, Bei Wang, Yuting Zhu, Yang Ding, Yongjuan Ding, Xia L. Naturally Equipped Urinary Exosomes Coated Poly (2-ethyl-2-oxazoline)-Poly (D, L-lactide) Nanocarriers for the Pre-Clinical Translation of Breast Cancer. Bioengineering (Basel, Switzerland). vol 9. issue 8. 2022-08-25. PMID:36004889. |
in vitro experiments revealed that uepp-d nps exhibited significantly improved cellular uptake, cytotoxicity, and apoptosis in mcf-7 cell lines as compared to dox-loaded peoz-pla nanoparticles (pp-d nps) and free dox. |
2022-08-25 |
2023-08-14 |
mouse |
| Quan Wang, Hongshu Jing, Jun Lin, Zhihua Wu, Yu Tian, Ke Gong, Qianqian Guo, Xupeng Yang, Liting Wang, Zhaojun Li, Yourong Dua. Programmed prodrug breaking the feedback regulation of P-selectin in plaque inflammation for atherosclerotic therapy. Biomaterials. 2022-08-24. PMID:36002347. |
functionally, li nps could interfere with p-selectin in the inflammatory process, such as inhibiting macrophage adhesion, reducing the secretion of inflammatory factors, and inducing macrophage apoptosis. |
2022-08-24 |
2023-08-14 |
mouse |
| Murat Doga. Assessment of mechanism involved in the apoptotic and anti-cancer activity of Quercetin and Quercetin-loaded chitosan nanoparticles. Medical oncology (Northwood, London, England). vol 39. issue 11. 2022-08-23. PMID:35999475. |
overall, quercetin and quercetin-loaded chitosan nps caused significant cytotoxicity in sh-sy5y cells via producing oxidative stress, dna damage, and eventually apoptosis. |
2022-08-23 |
2023-08-14 |
Not clear |
| Jun Yang, Jieqiong Lin, Xianxiang Chen, Liyuan Rong, Mingyue Shen, Yuanxing Wang, Jianhua Xi. Mesona chinensis polysaccharide/zein nanoparticles to improve the bioaccesibility and in vitro bioactivities of curcumin. Carbohydrate polymers. vol 295. 2022-08-21. PMID:35989015. |
studies on in vitro antitumor activity of zmc nps showed that they could enter hepatocellular carcinoma cells, induce cell apoptosis, promote ros production, and alter mitochondrial membrane potential, showing higher in vitro antitumor activity compared to free curcumin. |
2022-08-21 |
2023-08-14 |
Not clear |
| Pengxiao Li, Xiaoyuan Guo, Ting Liu, Qing Liu, Jie Yang, Guoyun Li. Evaluation of Hepatoprotective Effects of Piperlongumine Derivative PL 1-3-Loaded Albumin Nanoparticles on Lipopolysaccharide/d-Galactosamine-Induced Acute Liver Injury in Mice. Molecular pharmaceutics. 2022-08-16. PMID:35971845. |
1-3 nps treatment can inhibit inflammation, oxidative stress, and apoptosis via the downregulation of nf-κb signaling pathways, the activation of nrf2/ho-1 signaling pathways, and the inhibition of expression of bax and caspase 3 proteins. |
2022-08-16 |
2023-08-14 |
mouse |
| Xingyu Nan, Xingkun Jin, Yu Song, Kaimin Zhou, Yukai Qin, Qun Wang, Weiwei L. Effect of polystyrene nanoplastics on cell apoptosis, glucose metabolism, and antibacterial immunity of Eriocheir sinensis. Environmental pollution (Barking, Essex : 1987). 2022-08-16. PMID:35973454. |
this study aimed to investigate the effects of ps nps on apoptosis and glucose metabolism in chinese mitten crabs, and whether ps nps could synergistically affect the antibacterial immunity of crabs. |
2022-08-16 |
2023-08-14 |
Not clear |
| Xingyu Nan, Xingkun Jin, Yu Song, Kaimin Zhou, Yukai Qin, Qun Wang, Weiwei L. Effect of polystyrene nanoplastics on cell apoptosis, glucose metabolism, and antibacterial immunity of Eriocheir sinensis. Environmental pollution (Barking, Essex : 1987). 2022-08-16. PMID:35973454. |
the rna sequencing data showed that after hemocytes endocytosed nps, apoptosis and glucose metabolism-related gene expression was significantly induced, resulting in abnormal cell apoptosis and a glucose metabolism disorder. |
2022-08-16 |
2023-08-14 |
Not clear |