| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Reza Malekzadeh, Tohid Mortezazadeh, Waleed K Abdulsahib, Behnaz Babaye Abdollahi, Michael R Hamblin, Behzad Mansoori, Fahad Alsaikhan, Bo Zen. Nanoarchitecture-based photothermal ablation of cancer: A systematic review. Environmental research. 2023-07-24. PMID:37487920. |
the presence of nps during ptt can increase the reactive generation of oxygen species, damage the dna and mitochondria, leading to cancer cell death mainly via apoptosis. |
2023-07-24 |
2023-08-14 |
Not clear |
| Lihui Xuan, Zhao Ju, Magdalena Skonieczna, Ping-Kun Zhou, Ruixue Huan. Nanoparticles-induced potential toxicity on human health: Applications, toxicity mechanisms, and evaluation models. MedComm. vol 4. issue 4. 2023-07-17. PMID:37457660. |
furthermore, we unravels the underlying mechanisms of nps including ros accumulation, mitochondrial damage, inflammatory reaction, apoptosis, dna damage, cell cycle, and epigenetic regulation. |
2023-07-17 |
2023-08-14 |
mouse |
| Aifen Liu, Jingyan Hu, Tzu-Shao Yeh, Chengniu Wang, Jilong Tang, Xiaohong Huang, Bin Chen, Liexiang Huangfu, Weili Yu, Lei Zhan. Neuroprotective Strategies for Stroke by Natural Products: Advances and Perspectives. Current neuropharmacology. 2023-07-17. PMID:37458258. |
then we propose the comprehensive neuroprotective mechanism of nps in cerebral ischemic stroke, which involves complex cascade processes of oxidative stress, mitochondrial damage, apoptosis or ferroptosis-related cell death, inflammatory response, and disruption of the blood- brain barrier (bbb). |
2023-07-17 |
2023-08-14 |
Not clear |
| Eda Argitekin, Esra Ersoz-Gulseven, Gulcin Cakan-Akdogan, Yasar Akdoga. Dopamine-Conjugated Bovine Serum Albumin Nanoparticles Containing pH-Responsive Catechol-V(III) Coordination for In Vitro and In Vivo Drug Delivery. Biomacromolecules. 2023-07-14. PMID:37450837. |
it was shown that d-bsa nps entered cancerous mcf-7 cells (66%) more efficiently than non-cancerous hek293t (33%) in 3 h. also, dox-loaded nps reduced cell viability of mcf-7 by 75% and induced apoptosis in a majority of cells after 24 h. biodegradability and lack of hemolytic activity were shown in vitro, whereas a lack of toxicity was shown in histological sections of zebrafish. |
2023-07-14 |
2023-08-14 |
cattle |
| Suresh Mickymaray, Mohammed Saleh Al Aboody, Mostafa M Eraqi, Wardha A Alhoqail, Abdulaziz S Alothaim, Kaviya Suresh, Palanisamy Arulselva. Chitosan-encapsulated nickel oxide, tin dioxide, and farnesol nanoparticles: Antimicrobial and anticancer properties in breast cancer cells. International journal of biological macromolecules. 2023-07-14. PMID:37451381. |
the findings suggest that nps increased the number of reactive oxygen species (ros), changed the Δψm, and initiated apoptosis. |
2023-07-14 |
2023-08-14 |
Not clear |
| Asif Mohd Itoo, Milan Paul, Balaram Ghosh, Swati Biswa. Polymeric graphene oxide nanoparticles loaded with doxorubicin for combined photothermal and chemotherapy in triple negative breast cancer. Biomaterials advances. vol 153. 2023-07-12. PMID:37437383. |
the results demonstrated that the dox@go(mpp) (1/0.5) nps treatment with laser (+l) (808 nm) was highly efficient in inducing apoptosis, cell cycle arrest (g2/m) phase, significant cytotoxicity, mitochondrial membrane depolarization, ros generation, and photothermal effect leading to a higher proportion of cell death than free dox, and dox@go(mpp) (1/0.5) nps (-l). |
2023-07-12 |
2023-08-14 |
mouse |
| Abhishesh Kumar Mehata, Virendra Singh, Vikas, Nitesh Singh, Abhijit Mandal, Debabrata Dash, Biplob Koch, Madaswamy S Muth. Chitosan- ACS applied materials & interfaces. 2023-07-11. PMID:37433149. |
the nanoparticles (nps) were prepared by solvent evaporation using the ionic gelation method and characterized for particle size, zeta potential, polydispersity, surface morphology, surface chemistry, drug entrapment efficiency, cytotoxicity assay, cellular uptake, and apoptosis study. |
2023-07-11 |
2023-08-14 |
Not clear |
| De-Ping Wang, Jian Zheng, Fang-Ying Jiang, Li-Fei Wu, Mei-Yue Wang, Yu-Lan Wang, Chuan-Yue Qin, Jun-Ya Ning, Ji-Min Cao, Xin Zho. Facile and green fabrication of tumor- and mitochondria-targeted AIEgen-protein nanoparticles for imaging-guided photodynamic cancer therapy. Acta biomaterialia. 2023-07-06. PMID:37414113. |
the nps also presented a mitochondria-targeting ability, and efficiently generated reactive oxygen species (ros) upon visible light irradiation, making them valuable for inducing efficient mitochondrial dysfunction and intrinsic apoptosis in cancer cells. |
2023-07-06 |
2023-08-14 |
human |
| Yuanying Zhang, Nan Yang, Ziyi Dong, Jiahui Wu, Rui Liao, Yanling Zhang, Gege Zhang, Mengfei Ren, Feng Wang, Xiaochen Dong, Pingping Lian. Dual-Targeting Biomimetic Nanomaterials for Photo-/Chemo-/Antiangiogenic Synergistic Therapy. ACS applied materials & interfaces. 2023-07-03. PMID:37400422. |
the mbpp nps exhibit high biocompatibility, superb phototoxicity, excellent antiangiogenic ability, and double-trigging cancer cell apoptosis in vitro. |
2023-07-03 |
2023-08-14 |
Not clear |
| Xia Cao, Tianwen Deng, Qin Zhu, Jianping Wang, Wenwan Shi, Qi Liu, Qintong Yu, Wenwen Deng, Jiangnan Yu, Qilong Wang, Gao Xiao, Ximing X. Photothermal Therapy Mediated Hybrid Membrane Derived Nano-formulation for Enhanced Cancer Therapy. AAPS PharmSciTech. vol 24. issue 6. 2023-06-28. PMID:37380936. |
compared to the normal section, pdt-mediated eg@emhm nps could induce an early stage of apoptosis of b16. |
2023-06-28 |
2023-08-14 |
Not clear |
| Fan Zhao, Hongyan Yu, Liying Liang, Chen Wang, Dier Shi, Xiangyu Zhang, Yao Ying, Wei Cai, Wangchang Li, Juan Li, Jingwu Zheng, Liang Qiao, Shenglei Che, Jing Y. Redox Homeostasis Disruptors Based on Metal-Phenolic Network Nanoparticles for Chemo/Chemodynamic Synergistic Tumor Therapy Through Activating Apoptosis and Cuproptosis. Advanced healthcare materials. 2023-06-27. PMID:37369362. |
herein, metal-phenolic network nanoparticles (nps) self-assembled from copper ions and gallic acid (cu-ga) are developed to evoke apoptosis and cuproptosis for synergistic chemo/chemodynamic therapy. |
2023-06-27 |
2023-08-14 |
Not clear |
| Kexin Zhang, Jiaxin Zhu, Ruyi Wang, Wanfang Zhu, Zhongtao Zhang, Liangping Gong, Feng Feng, Wenyuan Liu, Lingfei Han, Wei Q. Mitochondria-Anchoring Self-assembled Nanoparticles for Multi-Path Energy Depletion: A "Nano Bomb" in Chemo-co-Starvation Therapy. International journal of pharmaceutics. 2023-06-26. PMID:37364784. |
besides, apoptosis via mitochondria pathway and mitochondria fragmentation supported the hypothesis that nps eliminated mda-mb-231 cells by violently attacking mda-mb-231 cells and especially the mitochondria. |
2023-06-26 |
2023-08-14 |
Not clear |
| Zhuoting Lu, Jingyu Li, Baohong Chen, Jiayu Feng, Qinglian Hu, Yuanxiang Jin, Zhengwei F. Mitochondria Targeted Nanoparticles Potentiate Tumor Chemo-Phototherapy by Toxic Oxidative Stress Mediated Oxeiptosis. Macromolecular bioscience. 2023-06-09. PMID:37295777. |
also, m-icg-ptx nps exhibited higher tumor growth inhibition ability by promoting cell apoptosis and oxeiptosis pathway, and high effective inhibition of primary tumor growth and tumor metastasis. |
2023-06-09 |
2023-08-14 |
Not clear |
| Chenxi Zhu, Wenzong Zhou, Mingming Han, Ying Yang, Yiming Li, Qichen Jiang, Weiwei L. Dietary polystyrene nanoplastics exposure alters hepatic glycolipid metabolism, triggering inflammatory responses and apoptosis in Monopterus albus. The Science of the total environment. 2023-05-29. PMID:37247739. |
overexpression of the cytokines genes interleukin 1 (il1b) and interleukin-8 (il8), tumor necrosis factor alpha (tnf-α), activation of mapk signaling pathway, and increased gene expression of c-jun amino-terminal kinases (jnk) and p38 indicate that exposure to nps may lead to hepatopancreas apoptosis through oxidative stress and inflammation. |
2023-05-29 |
2023-08-14 |
cat |
| Fernanda M P Tonelli, Flávia C P Tonelli, Helon G Cordeir. TiO2 Nanoparticles in Cancer Therapy as Nanocarriers in Paclitaxel's Delivery and Nanosensitizers in Phototherapies and/or Sonodynamic Therapy. Current pharmaceutical biotechnology. 2023-05-19. PMID:37202892. |
signaling pathways triggered by this nanomaterial inside cells leading to apoptosis (a desirable fate when targeting tumor cells) and challenges related to the clinical translation of these nps will also receive attention in the future. |
2023-05-19 |
2023-08-14 |
Not clear |
| Jingyan Yi, Xin Luo, Jinshan Xing, Aharon Gedanken, Xiukun Lin, Chunxiang Zhang, Gan Qia. Micelle encapsulation zinc-doped copper oxide nanocomposites reverse Olaparib resistance in ovarian cancer by disrupting homologous recombination repair. Bioengineering & translational medicine. vol 8. issue 3. 2023-05-19. PMID:37206208. |
in addition to affecting cell proliferation, migration, apoptosis and autophagy, menzn-cuo nps have a greater potential for clinical application by inducing hr repair defects in ovarian cancer cells in combination with poly (adp-ribose) polymerase inhibitors for lethal effects. |
2023-05-19 |
2023-08-14 |
human |
| Yeneng Guan, Aqin Yan, Wei Qiang, Rui Ruan, Chaobo Yang, Kai Ma, Hongmei Sun, Mingxing Liu, Hongda Zh. Selective Delivery of Tofacitinib Citrate to Hair Follicles Using Lipid-Coated Calcium Carbonate Nanocarrier Controls Chemotherapy-Induced Alopecia Areata. International journal of molecular sciences. vol 24. issue 9. 2023-05-14. PMID:37176141. |
compared to the topical application of tfc solution, pl/acc-tfc nps significantly inhibited apoptosis of mouse hair follicles and accelerated hair growth. |
2023-05-14 |
2023-08-14 |
mouse |
| Yunhao Li, Yujuan Gao, Zian Pan, Fan Jia, Chenlu Xu, Xinyue Cui, Xuan Wang, Yan W. Fabrication of Poly Dopamine@poly (Lactic Acid-Co-Glycolic Acid) Nanohybrids for Cancer Therapy via a Triple Collaboration Strategy. Nanomaterials (Basel, Switzerland). vol 13. issue 9. 2023-05-14. PMID:37176991. |
in the drug-loaded pda co-delivery nanohybrids (pda@plga/dc nps), dox and ca4 synergistically induced tumor cell apoptosis by interfering with dna replication and inhibiting tumor angiogenesis, respectively. |
2023-05-14 |
2023-08-14 |
Not clear |
| Saima Maher, Shazia Nisar, Sania Muhammad Aslam, Farooq Saleem, Farida Behlil, Muhammad Imran, Mohammed A Assiri, Arifa Nouroz, Nadra Naheed, Zarmina Azad Khan, Parveen Asla. Synthesis and Characterization of ZnO Nanoparticles Derived from Biomass ( ACS omega. vol 8. issue 18. 2023-05-14. PMID:37179630. |
the zinc oxide (zno) nps can precisely and captivatingly promote the apoptosis of cancer cells in cancer treatment. |
2023-05-14 |
2023-08-14 |
Not clear |
| Mohamed Haider, Jayalakshmi Jagal, Khuloud Bajbouj, Basma M Sharaf, Lina Sahnoon, Javan Okendo, Mohammad H Semreen, Mawieh Hamda, Nelson C Soare. Integrated multi-omics analysis reveals unique signatures of paclitaxel-loaded poly(lactide-co-glycolide) nanoparticles treatment of head and neck cancer cells. Proteomics. 2023-05-06. PMID:37148169. |
functional cell assays revealed that ptx-plga nps treated cells had a higher level of apoptosis than ptx alone, whereas the complementary, uhplc-ms/ms (tims-tof) based multi-omics analyses revealed that ptx-plga nps treatment resulted in increased abundance of proteins associated with tubulin, as well as metabolites such as 5-thymidylic acid, pc(18:1(9z)/18:1(9z0), vitamin d, and sphinganine among others. |
2023-05-06 |
2023-08-14 |
Not clear |