| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Liwei Wei, Qingqing Pan, Junyan Teng, Hong Zhang, Na Qi. Intra-articular administration of PLGA resveratrol sustained-release nanoparticles attenuates the development of rat osteoarthritis. Materials today. Bio. vol 24. 2024-01-04. PMID:38173866. |
mechanistic studies indicated that rsv-loaded plga nps inhibit apoptosis and promote autophagy. |
2024-01-04 |
2024-01-06 |
rat |
| Raquel Martin-Folgar, Mª Carmen González-Caballero, Mónica Torres-Ruiz, Ana I Cañas-Portilla, Mercedes de Alba González, Isabel Liste, Mónica Morale. Molecular effects of polystyrene nanoplastics on human neural stem cells. PloS one. vol 19. issue 1. 2024-01-03. PMID:38170698. |
our results showed that nps can induce oxidative stress, cellular stress, dna damage, alterations in inflammatory response, and apoptosis, which could lead to tissue damage and neurodevelopmental diseases. |
2024-01-03 |
2024-01-06 |
human |
| Rina Matsui, Katsunori Endo, Takeru Saiki, Hazuki Haga, Weidong Shen, Xiangdong Wang, Shinya Yamazaki, Shigeru Katayama, Kenji Nagata, Hidemitsu Kitamura, Sachi Tanak. Characterization and anti-tumor activities of polysaccharide isolated from Brassica rapa L. via activation of macrophages through TLR2-and TLR4-Dependent pathways. Archives of biochemistry and biophysics. 2023-12-31. PMID:38160699. |
furthermore, nps induced apoptosis significantly against 4t1 murine breast cancer cells cultured in conditioned medium from nps-treated macrophages through tumor necrosis factor-α. |
2023-12-31 |
2024-01-05 |
mouse |
| Yuanyuan Yao, Tianlong Wu, Lili Pan, Shuzhen Yan, Shuqin Yu, Shuanglin Che. The evaluation of four nano-formulations loaded-Elsinochrome A on characteristics and in vitro cytotoxicity effect. Journal of biomaterials applications. 2023-12-28. PMID:38154025. |
upon exposure to 460 nm light, plga/ea nps induced a significant reduction in a549 cell viability to 13.8% and an apoptosis rate of 93.8%, whereas mpeg-pcl/ea nms elicited a decrease in mcf-7 cell viability to 12.8% and an apoptosis rate of 73.0%. |
2023-12-28 |
2023-12-31 |
Not clear |
| Fahimeh Badparvar, Ahmad Poursattar Marjani, Roya Salehi, Fatemeh Ramezan. pH/redox responsive size-switchable intelligent nanovehicle for tumor microenvironment targeted DOX release. Scientific reports. vol 13. issue 1. 2023-12-18. PMID:38110480. |
apoptosis tests confirmed that the cells treated with dox-loaded nps showed a higher amount of apoptosis (71.6%) than the free dox (49.8%). |
2023-12-18 |
2023-12-21 |
Not clear |
| Zihan He, Haoying Song, Jingjing Cheng, Wenxiu Qiu, Junjie Hu, Zhenpeng Qiu, Qi Wang, Cong Chang, Guohua Zheng, Yan Men. Selenium Nanoparticles Stabilized by β-Glucan Nanotubes from Black Fungus and Their Effects on the Proliferation, Apoptosis, and Cell Cycle of HepG2 Cells. ACS omega. vol 8. issue 48. 2023-12-11. PMID:38075754. |
moreover, bfp-se showed significant effects on the proliferation, apoptosis, and cell cycle of hepg2 cells compared to those exhibited by se nps. |
2023-12-11 |
2023-12-17 |
human |
| Zhuo Xiang, Lingling Xu, Yizhu Shan, Xi Cui, Bojing Shi, Yuan Xi, Panxing Ren, Xuemei Zheng, Chaochao Zhao, Dan Luo, Zhou L. Tumor microenviroment-responsive self-assembly of barium titanate nanoparticles with enhanced piezoelectric catalysis capabilities for efficient tumor therapy. Bioactive materials. vol 33. 2023-12-07. PMID:38059123. |
tma-bto nps exhibited differential cytotoxicity against tumor cells and normal cells, and the stronger piezoelectric catalysis and mechanical damage induced by the assemblies resulted in significant apoptosis of mouse breast cancer cells (4t1); while there was little damage to mouse embryo osteoblast precursor cells (mc3t3-e1) under the same treatment conditions. |
2023-12-07 |
2023-12-10 |
mouse |
| Shihang Xu, Weicong Luo, Minghui Zhu, Lei Zhao, Lijuan Gao, Hong Liang, Zhenlei Zhang, Feng Yan. Human Serum Albumin-Platinum(II) Agent Nanoparticles Inhibit Tumor Growth Through Multimodal Action Against the Tumor Microenvironment. Molecular pharmaceutics. 2023-11-28. PMID:38015620. |
in addition, the hsa-his242-pt-dp44mt nps were found to kill cancer cells by inducing apoptosis, autophagy, and inhibiting angiogenesis. |
2023-11-28 |
2023-12-07 |
human |
| Siyi Liu, Min Liu, Jingya Xiu, Tian Zhang, Bowen Zhang, Dongyun Cun, Chunrong Yang, Kexin Li, Jiulong Zhang, Xiuli Zha. Celastrol-Loaded Bovine Serum Albumin Nanoparticles Target Inflamed Neutrophils for Improved Rheumatoid Arthritis Therapy. Acta biomaterialia. 2023-11-28. PMID:38013018. |
studies have demonstrated that cbr nps can selectively target circulating ines and induce ines apoptosis. |
2023-11-28 |
2023-11-29 |
mouse |
| Siyi Liu, Min Liu, Jingya Xiu, Tian Zhang, Bowen Zhang, Dongyun Cun, Chunrong Yang, Kexin Li, Jiulong Zhang, Xiuli Zha. Celastrol-Loaded Bovine Serum Albumin Nanoparticles Target Inflamed Neutrophils for Improved Rheumatoid Arthritis Therapy. Acta biomaterialia. 2023-11-28. PMID:38013018. |
cbr nps were prepared for the first time to induce apoptosis of ines; cbr nps could inhibit the release of nets while inducing apoptosis of ines in vivo and vitro cellular experiments; cbr nps had favorable anti-inflammatory effects and low toxicity side-effects in collagen-induced arthritis (cia) mouse models. |
2023-11-28 |
2023-11-29 |
mouse |
| Melayshia McFadden, Santosh Kumar Singh, Briana Kinnel, Sooryanarayana Varambally, Rajesh Sing. The effect of paclitaxel- and fisetin-loaded PBM nanoparticles on apoptosis and reversal of drug resistance gene ABCG2 in ovarian cancer. Journal of ovarian research. vol 16. issue 1. 2023-11-22. PMID:37990267. |
the present study shows that targeting folate receptor alpha (frα) through planetary ball milling (pbm) nanoparticles (nps) induces apoptosis in ovca cells. |
2023-11-22 |
2023-11-29 |
Not clear |
| Thangavelu Indumathi, Inbavalli Kumaresan, Jagadeesh Suriyaprakash, Abdullah A Alarfaj, Abdurahman Hajinur Hirad, Ravindran Jaganathan, Maghimaa Mathanmohu. Synthesis and characterization of 4-nitro benzaldehyde with ZnO-based nanoparticles for biomedical applications. Journal of basic microbiology. 2023-11-21. PMID:37988661. |
in addition, the influence of synthesized nps on cell apoptosis, cell viability, mitochondrial membrane potential (mmp), endogenous reactive oxygen species (ros) production, apoptosis, and cell adhesion was also examined. |
2023-11-21 |
2023-11-29 |
Not clear |
| Thangavelu Indumathi, Inbavalli Kumaresan, Jagadeesh Suriyaprakash, Abdullah A Alarfaj, Abdurahman Hajinur Hirad, Ravindran Jaganathan, Maghimaa Mathanmohu. Synthesis and characterization of 4-nitro benzaldehyde with ZnO-based nanoparticles for biomedical applications. Journal of basic microbiology. 2023-11-21. PMID:37988661. |
the cell adhesion test revealed that 4nbzno nps reduced cell adhesion and may promote apoptosis of cancer cells because of enhanced ros levels. |
2023-11-21 |
2023-11-29 |
Not clear |
| Jing-Qing Le, Xun-Huan Song, Ling-Wu Tong, Ying-Qi Lin, Ke-Ke Feng, Yi-Fan Tu, Yong-Shan Hu, Jing-Wei Sha. Dual-drug controllable co-assembly nanosystem for targeted and synergistic treatment of hepatocellular carcinoma. Journal of colloid and interface science. vol 656. 2023-11-21. PMID:37989051. |
furthermore, these nps caused more significant mitochondrial membrane potential reduction and cell apoptosis. |
2023-11-21 |
2023-11-29 |
mouse |
| Tong Chen, Lin Zhang, Liangyu Yao, Jiaochen Luan, Xiang Zhou, Rong Cong, Xuejiang Guo, Chao Qin, Ninghong Son. Zinc oxide nanoparticles-induced testis damage at single-cell resolution: Depletion of spermatogonia reservoir and disorder of Sertoli cell homeostasis. Environment international. vol 181. 2023-11-02. PMID:37918063. |
mechanically, zno nps triggered fatty acid accumulation in gc-1 cells through protein kinase b (akt)/mammalian target of rapamycin (mtor) signaling and peroxisome proliferator-activated receptor alpha (pparα)/acyl-coa oxidase 1 (acox1) axis, contributing to cell apoptosis. |
2023-11-02 |
2023-11-08 |
rat |
| Tong Chen, Lin Zhang, Liangyu Yao, Jiaochen Luan, Xiang Zhou, Rong Cong, Xuejiang Guo, Chao Qin, Ninghong Son. Zinc oxide nanoparticles-induced testis damage at single-cell resolution: Depletion of spermatogonia reservoir and disorder of Sertoli cell homeostasis. Environment international. vol 181. 2023-11-02. PMID:37918063. |
in vitro and in vivo experiments verified that zno nps disrupted blood-testis barrier formation and growth factors synthesis, which subsequently inhibited the proliferation and induced the apoptosis of spermatogonia. |
2023-11-02 |
2023-11-08 |
rat |
| Tong Chen, Lin Zhang, Liangyu Yao, Jiaochen Luan, Xiang Zhou, Rong Cong, Xuejiang Guo, Chao Qin, Ninghong Son. Zinc oxide nanoparticles-induced testis damage at single-cell resolution: Depletion of spermatogonia reservoir and disorder of Sertoli cell homeostasis. Environment international. vol 181. 2023-11-02. PMID:37918063. |
as for the macrophages, zno nps activated oxidative stress of raw264.7 cells through nuclear factor erythroid 2-related factor 2 (nrf2)/heme oxygenase-1 (ho-1) pathway and promoted cell apoptosis through extracellular signal-regulated kinase (erk) 1/2 pathway. |
2023-11-02 |
2023-11-08 |
rat |
| Rohan Ghadi, Pawan Kumar Pandey, Akash Gabhale, Aaradhya Wadikar, M Dharshini, Kaushik Kuche, Tushar Date, Sanyog Jai. Genipin-Crosslinked Albumin Nanoparticles Containing Neratinib and Silibinin: A Dual-Death Therapy for Triple Negative Breast Cancer. International journal of pharmaceutics. 2023-11-02. PMID:37918494. |
a combined therapy using neratinib (ntb; ferroptosis inducer) and silibinin (slb; apoptosis inducer) via albumin-based nanocarriers (n-s alb nps) was explored to target tnbc. |
2023-11-02 |
2023-11-08 |
Not clear |
| Yu-Chen Lo, Wen-Jen Li. Improve BBB Penetration and Cytotoxicity of Palbociclib in U87-MG Glioblastoma Cells Delivered by Dual Peptide Functionalized Nanoparticles. Pharmaceutics. vol 15. issue 10. 2023-10-30. PMID:37896189. |
moreover, pbc@nps significantly enhanced u87-mg glioma cell apoptosis by 2.3-6.5 folds relative to pbc, where the dual-peptide modified nps was the most effective one. |
2023-10-30 |
2023-11-08 |
Not clear |
| Miaomiao Yuan, Tong Chen, Lu Jin, Peng Zhang, Luoyijun Xie, Shuyi Zhou, Lianfeng Fan, Li Wang, Cai Zhang, Ning Tang, LiHao Guo, Chengmei Xie, Yanhong Duo, Ling Li, Leilei Sh. A carrier-free supramolecular nano-twin-drug for overcoming irinotecan-resistance and enhancing efficacy against colorectal cancer. Journal of nanobiotechnology. vol 21. issue 1. 2023-10-30. PMID:37898773. |
the ir and nir self-assembled nano-twin-drug of (nir-ir nps) could enhance the therapeutic effect on crc by synergistically inhibiting the dna damage repair pathway and activating the tumor cell apoptosis process without obvious toxicity. |
2023-10-30 |
2023-11-08 |
Not clear |