| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jian Li, Tingting Wang, Cijuan Li, Xun Zhang, Jingchao Li, Dongsheng Zhang, Yafei Zhang, Jun Yang, Xinhui Su, Nian Li. Boosting Tumor Accumulation of Phthalocyanine through Sialylation Engineering for Superior Cancer Phototherapy. Advanced healthcare materials. 2024-11-18. PMID:39555670. |
besides, the phototoxicity of znpc-4sa nps can effectively trigger cell apoptosis and tumor elimination upon laser irradiation. |
2024-11-18 |
2024-11-22 |
Not clear |
| Yan-Yang Lu, Weizhen Hua, Yiqiong Sun, Lu Lu, Hongyun Ren, Qingyu Huan. Proteomics reveals that nanoplastics with different sizes induce hepatocyte apoptosis in mice through distinct mechanisms involving mitophagy dysregulation and cell cycle arrest. Toxicology research. vol 13. issue 6. 2024-11-14. PMID:39539253. |
nanoplastics (nps) can penetrate the intestinal barrier of organisms and accumulate in the liver, thereby inducing hepatocyte apoptosis. |
2024-11-14 |
2024-11-17 |
mouse |
| Merve Erden Tüçer, Suat Tüçer, Nazlıcan Tunç, Rana Acar, Duygu Deniz Usta, Kouroush Salimi, Özlen Konu, Urartu Özgür Şafak Şeke. Transcriptomic Investigation of NP Toxicity on HepaRG Spheroids. Chemico-biological interactions. 2024-11-08. PMID:39515631. |
remarkably, processes such as drug metabolism, sensitivity to metal ions, oxidative stress, endothelial-mesenchymal transition (emt) and apoptosis consistently exhibited significant enrichment across all nps of different materials. |
2024-11-08 |
2024-11-17 |
Not clear |
| Xiao-Yin Wang, Ao-Qiu Chen, Jing Huang, Jiang-Hong Luo, Qi Zo. A review on structure, bioactivity, mechanism, structure-activity relationship and application of anti-breast cancer polysaccharides. International journal of biological macromolecules. 2024-10-30. PMID:39476909. |
the anti-bc mechanisms of nps include anti-proliferation, inducing apoptosis, anti-metastasis and anti-invasion, immunoenhancement, gut microbiota regulation and others. |
2024-10-30 |
2024-11-02 |
Not clear |
| Sakine Shirvalilou, Samideh Khoei, Reza Afzalipour, Habib Ghaznavi, Milad Shirvaliloo, Zahra Derakhti, Roghayeh Sheervalilo. Targeting the undruggable in glioblastoma using nano-based intracellular drug delivery. Medical oncology (Northwood, London, England). vol 41. issue 12. 2024-10-29. PMID:39470962. |
recent studies show that combining photothermal therapy with magnetic hyperthermia using aunps and magnetic nps induces ros-dependent apoptosis and immunogenic cell death providing dual-targeted, immune-activating approaches. |
2024-10-29 |
2024-11-02 |
Not clear |
| Furkan Eker, Hatice Duman, Emir Akdaşçi, Anna Maria Witkowska, Mikhael Bechelany, Sercan Kara. Silver Nanoparticles in Therapeutics and Beyond: A Review of Mechanism Insights and Applications. Nanomaterials (Basel, Switzerland). vol 14. issue 20. 2024-10-26. PMID:39452955. |
the underlying processes by which silver nps exercise their effects, such as oxidative stress induction, apoptosis, and microbial cell membrane rupture, are explored. |
2024-10-26 |
2024-10-28 |
Not clear |
| Qiuyue Lai, Wenlong Li, Dandan Hu, Zhenqiu Huang, Mingyu Wu, Shun Feng, Yu Wa. Hepatic stellate cell-targeted chemo-gene therapy for liver fibrosis using fluorinated peptide-lipid hybrid nanoparticles. Journal of controlled release : official journal of the Controlled Release Society. 2024-10-22. PMID:39437969. |
thus, sf-sihsp47@vfpl nps demonstrated optimal antifibrotic effects by triggering apoptosis and ferroptosis in ahscs. |
2024-10-22 |
2024-10-25 |
mouse |
| Xiaodan Xu, Yuanyuan He, Jungang Li. Berberine: A multifaceted agent for lung cancer treatment-from molecular insight to clinical applications. Gene. 2024-10-20. PMID:39427827. |
abbreviations: bbr, berberine; emt, epithelial-mesenchymal transition; nsclc, non-small cell lung cancer; ros, reactive oxygen species; ask1, apoptosis signal-regulating kinase 1; jnk, c-jun n-terminal kinase; bhc, berberine hydrochloride; dsb, double-strand breaks; csn, cop9 signalosome; nir, near-infrared; llc, lewis lung carcinoma; rtk, receptor tyrosine kinase; b-phyt-lcns, berberine-phytantriol liquid crystalline nanoparticles; er, endoplasmic reticulum; ber-lcns, berberine-loaded liquid crystalline nanoparticles; bns, berberine nanostructure; ber-cs-nps, berberine-loaded chitosan nanoparticles; b-phyt-lcns, berberine-phytantriol liquid crystalline nanoparticles; b-phyt-lcns, berberine-loaded liquid crystalline nanoparticles; ber-lcns, berberine-loaded liquid crystalline nanoparticles; b-zno nps, berberine-loaded zinc oxide nanoparticles; b-c60, berberine-c60 complex; ltp, low-temperature plasma. |
2024-10-20 |
2024-10-23 |
Not clear |
| Marwa H Hassan, Ibrahim A Emam, Haitham Farghali, Marwa A Ibrahim, Neven H Hassan, Khaled Y Farroh, Eman I Hassane. Toxicological screening of zinc oxide nanoparticles in mongrel dogs after seven days of repeated subcutaneous injections. BMC veterinary research. vol 20. issue 1. 2024-10-19. PMID:39425163. |
it was concluded that the daily sc injections of dogs with zno nps at concentrations of 50 and 100 ppm caused extensive oxidative stress damage in various organs which provoked serious pathological processes such as apoptosis and inflammation. |
2024-10-19 |
2024-10-21 |
Not clear |
| Xueyan Hou, Jingjing Xu, Yuxin Wang, Jingya Zhao, Yalin Guan, Xue Yang, Tenglong Xu, Kun Du, Sisi He, Yongli Sh. Triggering Pyroptosis by Doxorubicin-Loaded Multifunctional Nanoparticles in Combination with Decitabine for Breast Cancer Chemoimmunotherapy. ACS applied materials & interfaces. 2024-10-16. PMID:39413405. |
in vivo experiments further demonstrated the antitumor efficacy of dac + dox@fpsd nps, and the 4t1-bearing mice treated with dac + dox@fpsd nps exhibited reduced tumor volumes, minimized tumor weights, decreased ki67-positive cells, increased tunel apoptosis ratios, and pronounced lesions in h&e staining. |
2024-10-16 |
2024-10-19 |
mouse |
| Wenjun Hou, Yifan Zou, Jie Li, Hui Jiang, Jinyu Li, Jie Wu, Senlin Zhu, Yan Ding, Huae Xu, Feng Jia, Xiaolin L. Synergistic Therapy of Melanoma by Co-Delivery of Dacarbazine and Ferroptosis-Inducing Ursolic Acid Using Biomimetic Nanoparticles. ACS omega. vol 9. issue 40. 2024-10-14. PMID:39398166. |
mtt, apoptosis assay, wound healing assay, colony formation assay, and immunohistochemistry were used to assess the antitumor effect of nps and rnps. |
2024-10-14 |
2024-10-16 |
Not clear |
| Cai-Shi Lin, Meng-Qi He, Meng-Ying An, Qi-Hang Zhao, Zhou-Hang Zhang, Ke-Yu Deng, Yongjian Ai, Hong-Bo Xi. Ultra-Small Copper-Based Multienzyme-Like Nanoparticles Protect Against Hepatic Ischemia-Reperfusion Injury Through Scavenging Reactive Oxygen Species in Mice. Small (Weinheim an der Bergstrasse, Germany). 2024-10-08. PMID:39377344. |
finally, it is demonstrated that the protective effects of cmp nps on hepatic iri are related to suppressing inflammation and hepatocytic apoptosis and maintaining endothelial functions through scavenging ros in liver tissues. |
2024-10-08 |
2024-10-10 |
mouse |
| Jialong Fan, Yan Qin, Wensheng Qiu, Jiahao Liang, Chang Xiao, Qian Xie, Chunyi Tong, Liqin Yuan, Ying Long, Bin Li. Gamabufotalin loaded micro-nanocomposites for multimodal therapy of metastatic TNBC by efficiently inducing ICD. Biomaterials. vol 314. 2024-10-04. PMID:39366186. |
in vitro and in vivo results have confirmed that cs-6@cpb nps were efficiently delivered to neoplastic tissue by the tumor hypoxic chemotaxis property of s.lux, wherein the nanomedicine induced significant tumor cell necroptosis and apoptosis via photothermal therapy (ptt) of cpb nps and chemotherapy of cs-6, which elicited icd and inhibited pd-l1 expression, resulting in dendritic cells (dcs) maturation and effector t cells activation to comprehensively eliminate tumors. |
2024-10-04 |
2024-10-07 |
Not clear |
| Yiming Li, Yucong Ye, Xiaoyi Zhu, Siwen Li, Na Rihan, Zongli Yao, Zhen Sun, Pengcheng Gao, Yunlong Zhao, Qifang La. Polystyrene nanoplastics induce apoptosis, histopathological damage, and glutathione metabolism disorder in the intestine of juvenile East Asian river prawns (Macrobrachium nipponense). The Science of the total environment. 2024-10-04. PMID:39366565. |
therefore, we used nps concentrations of 0, 5, 10, 20, 40 mg/l for 28 days of stress, evaluated the effects of nps exposure on intestinal cell apoptosis, histopathological damage, and glutathione (gsh) metabolism of juvenile east asian river prawns (macrobrachium nipponense). |
2024-10-04 |
2024-10-07 |
Not clear |
| Yiming Li, Yucong Ye, Xiaoyi Zhu, Siwen Li, Na Rihan, Zongli Yao, Zhen Sun, Pengcheng Gao, Yunlong Zhao, Qifang La. Polystyrene nanoplastics induce apoptosis, histopathological damage, and glutathione metabolism disorder in the intestine of juvenile East Asian river prawns (Macrobrachium nipponense). The Science of the total environment. 2024-10-04. PMID:39366565. |
our results showed that exposure to nps may induce apoptosis of intestinal tissue cells, induce autophagy, and inhibit gsh metabolism, thereby reducing intestinal immune function of m. nipponense. |
2024-10-04 |
2024-10-07 |
Not clear |
| Congjian He, Jiahui Zhou, Xixi Wu, Yujin Zhou, Siya Wang, Bo Liu, Ting Luo, Ying Chen, Jia Yuan, Di Wang, Chen Zhang, Jinfeng Sh. Hyaluronic acid-zein shell-core biopolymer nanoparticles enhance hepatocellular carcinoma therapy of celastrol via CD44-mediated cellular uptake. International journal of biological macromolecules. 2024-10-01. PMID:39353524. |
further studies revealed that cel/zein@ha nps induced apoptosis in hepatocellular carcinoma cells by modulating bax and bcl-2 expression, while also inhibiting tumor angiogenesis by decreasing cd31 and vegf levels. |
2024-10-01 |
2024-10-05 |
mouse |
| Yijing Zhao, Cong Song, Haijun Wang, Chengcheng Gai, Tingting Li, Yahong Cheng, Junjie Liu, Yan Song, Qian Luo, Bing Gu, Weiyang Liu, Liwei Chai, Dexiang Liu, Zhen Wan. Polydopamine-Cloaked Nanoarchitectonics of Prussian Blue Nanoparticles Promote Functional Recovery in Neonatal and Adult Ischemic Stroke Models. Biomaterials research. vol 28. 2024-09-19. PMID:39296854. |
apart from attenuating oxidative stress, pb@pda nps also suppressed neuronal apoptosis and counteracted inflammation, which effectively promote a short- and long-term functional recovery in hi mice. |
2024-09-19 |
2024-09-21 |
mouse |
| Zihan Xing, Zimin Cai, Liuya Mi, Juan Zhang, Jiaying Wang, Lizhu Chen, Mingzhe Xu, Bangguo Ma, Ruijia Tao, Bowen Yang, Xinmeng Lv, Lei Wang, Yancui Zhao, Xiaoli Liu, Liping Yo. Toxic effects of ZnO NPs on immune response and tissue pathology in Mytilus galloprovincialis. Aquatic toxicology (Amsterdam, Netherlands). vol 276. 2024-09-17. PMID:39288657. |
there was a downward trend in lysosomal membrane stability of m. galloprovincialis after exposure to zno nps for 96 h and 30 days, while ros and apoptosis rates increased significantly. |
2024-09-17 |
2024-09-20 |
human |
| Rongkai Cao, Yuxin Guo, Jiayue Liu, Yaqiong Guo, Xiang Li, Fuwei Xie, Yaqing Wang, Jianhua Qi. Assessment of nanotoxicity in a human placenta-on-a-chip from trophoblast stem cells. Ecotoxicology and environmental safety. vol 285. 2024-09-17. PMID:39288735. |
subsequent analysis indicated that cuo nps disrupted the autophagic flux in trophoblasts and induced apoptosis. |
2024-09-17 |
2024-09-20 |
human |
| Hanan I Elhenawy, Noura A Toto, Abdelazeem S Eltaweil, Hussein K Hussein, Maria Augustyniak, Lamia M El-Sama. Assessing the toxicity of green Agaricus bisporus-based Cadmium Sulfide nanoparticles on Musca domestica as a biological model. Scientific reports. vol 14. issue 1. 2024-09-14. PMID:39277622. |
cds nps caused disruptions in heat shock protein 70, cell apoptosis, and various biochemical components. |
2024-09-14 |
2024-09-18 |
Not clear |