| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yiming Li, Yucong Ye, Xiaoyi Zhu, Xingguo Liu, Xinfeng Li, Yunlong Zhao, Xuan Ch. Transcriptomic analysis reveals nanoplastics-induced apoptosis, autophagy and immune response in Litopenaeus vannamei. The Science of the total environment. 2024-07-03. PMID:38960190. |
high concentration (10 mg/l) of nps caused the destruction of hepatopancreas tissue structure, the shedding of microvilli, the increase number of hepatocyte apoptosis and autophagy structure. |
2024-07-03 |
2024-07-10 |
Not clear |
| Yiming Li, Yucong Ye, Xiaoyi Zhu, Xingguo Liu, Xinfeng Li, Yunlong Zhao, Xuan Ch. Transcriptomic analysis reveals nanoplastics-induced apoptosis, autophagy and immune response in Litopenaeus vannamei. The Science of the total environment. 2024-07-03. PMID:38960190. |
transcriptional sequencing analysis showed that the pathway of differentially expressed genes in kegg enrichment mainly included lysosome (ko04142), apoptosis (ko04210) pathways, indicating that the nps mainly affected the immune regulatory mechanism. |
2024-07-03 |
2024-07-10 |
Not clear |
| Yiming Li, Yucong Ye, Xiaoyi Zhu, Xingguo Liu, Xinfeng Li, Yunlong Zhao, Xuan Ch. Transcriptomic analysis reveals nanoplastics-induced apoptosis, autophagy and immune response in Litopenaeus vannamei. The Science of the total environment. 2024-07-03. PMID:38960190. |
our results indicated that nps exposure induced oxidative stress, apoptosis and autophagy in shrimps. |
2024-07-03 |
2024-07-10 |
Not clear |
| Ye Lin, Yuanyuan Tang, Ouyang Yi, Junping Zhu, Zhaoli Su, Gejing Li, Hua Zhou, Liang Liu, Bin Liu, Xiong Ca. Graphene oxide quantum dots-loaded sinomenine hydrochloride nanocomplexes for effective treatment of rheumatoid arthritis via inducing macrophage repolarization and arresting abnormal proliferation of fibroblast-like synoviocytes. Journal of nanobiotechnology. vol 22. issue 1. 2024-07-02. PMID:38951875. |
more notably, transcriptomic analyses revealed that ha@rfm@gp@sin nps suppressed the cell cycle pathway while inducing the cell apoptosis pathway. |
2024-07-02 |
2024-07-04 |
rat |
| Chongwen Ren, Qingqing Tu, Jinchao H. Fabrication of pH-responsive temozolomide (TMZ)-clacked tannic acid-altered zeolite imidazole nanoframeworks (ZIF-8) enhance anticancer activity and apoptosis induction in glioma cancer cells. Journal of biomaterials science. Polymer edition. 2024-07-02. PMID:38953298. |
the effectiveness of tmz@ta@zif-8 nps in inhibiting the migration and invasion of u251 glioma cancer cells, as well as promoting apoptosis, was confirmed through various tests, including mtt (3-(4,5)-dimethylthiahiazo(-z-y1)) assay, dapi/pi dual staining, and cell scratch assay. |
2024-07-02 |
2024-07-06 |
Not clear |
| Chongwen Ren, Qingqing Tu, Jinchao H. Fabrication of pH-responsive temozolomide (TMZ)-clacked tannic acid-altered zeolite imidazole nanoframeworks (ZIF-8) enhance anticancer activity and apoptosis induction in glioma cancer cells. Journal of biomaterials science. Polymer edition. 2024-07-02. PMID:38953298. |
the biochemical fluorescent staining assays showed that tmz@ta@zif-8 nps potentially improved ros, reduced mmp, and triggered apoptosis in u251 cells. |
2024-07-02 |
2024-07-06 |
Not clear |
| Hongjun Huang, Lerong Yang, Haoqiang He, Bo Zhou, Zainen Qin, Li Zheng, Chong She. Construction of mitochondrial-targeting nano-prodrug for enhanced Rhein delivery and treatment for osteoarthritis in vitro. International journal of pharmaceutics. 2024-06-30. PMID:38945463. |
moreover, rpt nps shows protection of mitochondrial membrane potential and inhibition of chondrocyte apoptosis. |
2024-06-30 |
2024-07-03 |
cat |
| Fahimeh Badparvar, Ahmad Poursattar Marjani, Roya Salehi, Fatemeh Ramezani, Hanieh Beyrampour Basmenj, Mehdi Taleb. Dual pH/redox-responsive size-switchable polymeric nano-carrier system for tumor microenvironment DTX release. Journal of biomaterials science. Polymer edition. 2024-06-30. PMID:38944817. |
the dtx-loaded nps showed more apoptosis (62.6 ± 3.7%) than the free dtx (51.8 ± 3.2%) in treated cells. |
2024-06-30 |
2024-07-02 |
Not clear |
| Huahui Zeng, Xiaohu Zeng, Can Wang, Guoqiang Wang, Qikang Tian, Junwei Zhao, Lingzhou Zhao, Ruiqin Li, Ying Luo, Haotian Peng, Zhenqiang Zhang, Xiaofang Li, Xiangxiang W. Combination therapy using Cel-CSO/Taxol NPs for reversing drug resistance in breast cancer through inhibiting PI3K/AKT/NF-κB/HIF-1α pathway. Drug delivery and translational research. 2024-06-26. PMID:38922561. |
nps effectively inhibited the overexpression of multidrug resistance-related protein p-gp, hypoxia inducible factor-1α (hif-1α), and triggered the mcf-7/taxol cell apoptosis through inhibiting the pi3k/akt/nf-κb/hif-1α pathway. |
2024-06-26 |
2024-06-29 |
mouse |
| Huahui Zeng, Xiaohu Zeng, Can Wang, Guoqiang Wang, Qikang Tian, Junwei Zhao, Lingzhou Zhao, Ruiqin Li, Ying Luo, Haotian Peng, Zhenqiang Zhang, Xiaofang Li, Xiangxiang W. Combination therapy using Cel-CSO/Taxol NPs for reversing drug resistance in breast cancer through inhibiting PI3K/AKT/NF-κB/HIF-1α pathway. Drug delivery and translational research. 2024-06-26. PMID:38922561. |
in tumor-bearing mice, nps exhibited significant curative effects in inducing apoptosis of mcf-7/taxol tumors which showed a low expression level of p-gp, microtubule-related proteins tubb3 and tau. |
2024-06-26 |
2024-06-29 |
mouse |
| Jinhong Guo, Wenjie Yan, Hao Duan, Diandian Wang, Yaxi Zhou, Duo Feng, Yue Zheng, Shiqi Zhou, Gaigai Liu, Xia Qi. Therapeutic Effects of Natural Products on Liver Cancer and Their Potential Mechanisms. Nutrients. vol 16. issue 11. 2024-06-19. PMID:38892575. |
finally, we analyze the potential mechanisms of nps in treating liver cancer, including inhibition of angiogenesis, migration, and invasion; regulation of the cell cycle; induction of apoptosis, autophagy, pyroptosis, and ferroptosis; influence on tumor metabolism; immune regulation; regulation of intestinal function; and regulation of key signaling pathways. |
2024-06-19 |
2024-06-21 |
Not clear |
| Haiting Liu, Guangqing Cai, Shuai Yuan, Xionghui Zhou, Rong Gui, Rong Huan. Platelet Membrane-Camouflaged Silver Metal-Organic Framework Biomimetic Nanoparticles for the Treatment of Triple-Negative Breast Cancer. Molecular pharmaceutics. 2024-06-10. PMID:38857525. |
we further revealed that pm@mof-ag nps induced tumor cell death by overproducing reactive oxygen species and promoting cell apoptosis. |
2024-06-10 |
2024-06-14 |
Not clear |
| Haiting Liu, Guangqing Cai, Shuai Yuan, Xionghui Zhou, Rong Gui, Rong Huan. Platelet Membrane-Camouflaged Silver Metal-Organic Framework Biomimetic Nanoparticles for the Treatment of Triple-Negative Breast Cancer. Molecular pharmaceutics. 2024-06-10. PMID:38857525. |
moreover, pm@mof-ag nps enhanced apoptosis by upregulating the ratios of bax/bcl-2 and cleaved caspase3/pro-caspase3. |
2024-06-10 |
2024-06-14 |
Not clear |
| WeiLu Jia, Meng Yang, WenNing Zhang, WenJing Xu, YeWei Zhan. Carrier-Free Self-Assembled Nanomedicines for Promoting Apoptosis and Inhibiting Proliferation in Hepatocellular Carcinoma. ACS biomaterials science & engineering. 2024-06-06. PMID:38841860. |
bi nps possessed the synergistic effects of promoting apoptosis, inhibiting proliferation and metastasis of tumors, and phototherapeutic treatment. |
2024-06-06 |
2024-06-08 |
Not clear |
| Niloofar Asadi, Mahmoud Gharbavi, Hamed Rezaeejam, Alireza Farajollahi, Behrooz Johar. Zinc nanoparticles coated with doxorubicin-conjugated alginate as a radiation sensitizer in triple-negative breast cancer cells. International journal of pharmaceutics. 2024-05-31. PMID:38821433. |
the zn@alg-dox nps significantly reduced cell growth, increased apoptosis, inhibited cell migration, and led to the arrest of different cell cycle phases in both conditions with and without x-ray exposure. |
2024-05-31 |
2024-06-02 |
Not clear |
| Archana M G, Anusree K S, Unnikrishnan B S, Reshma P L, Syama H P, Sreekutty J, Manu M Joseph, Sreelekha T . HER2 siRNA Facilitated Gene Silencing Coupled with Doxorubicin Delivery: A Dual Responsive Nanoplatform Abrogates Breast Cancer. ACS applied materials & interfaces. vol 16. issue 20. 2024-05-23. PMID:38739808. |
hsirna@pgd nps deciphered competent cancer cell internalization, enhanced cytotoxicity mediated via the induction of apoptosis, and excellent downregulation of the overexpressing target her2 gene. |
2024-05-23 |
2024-05-27 |
Not clear |
| Reena Sharma, Vivek Yadav, Shikha Jha, Sayali Dighe, Sanyog Jai. Unveiling the potential of ursolic acid modified hyaluronate nanoparticles for combination drug therapy in triple negative breast cancer. Carbohydrate polymers. vol 338. 2024-05-19. PMID:38763723. |
in vitro, ha-ua/ptx nps exhibited higher cytotoxicity, apoptosis, and mitochondrial depolarization compared to ptx alone. |
2024-05-19 |
2024-05-27 |
Not clear |
| Dan Zhang, Zhiyuan Wang, Hongmei Deng, Simeng Yi, Tao Li, Xinjiang Kang, Jun Li, Chang Li, Tingting Wang, Bo Xiang, Guang L. Zinc Oxide Nanoparticles Damage the Prefrontal Lobe in Mouse: Behavioral Impacts and Key Mechanisms. Toxicology letters. 2024-05-17. PMID:38759938. |
analysis of the degs based on fold change reveals that zno nps primarily regulate cell survival, proliferation, and apoptosis in neural cells, damaging the prefrontal lobe. |
2024-05-17 |
2024-05-27 |
mouse |
| Heba A H Abd Elhameed, Mai S Attia, Amira A A Mohamed, Shaimaa M I Alexeree, Eman I El Behery, Mahmoud Alagawany, Mayada R Farag, Alessandro Di Cerbo, Mahmoud M Azzam, Suzan Attia Mawe. The Role of Phthalocyanine-Gold Nanoconjugates (Pc-Au NCs) in Ameliorating the Hepatic and Renal Toxicity-Induced by Silver Nanoparticles (Ag NPs) in Male Rats. Biological trace element research. 2024-05-13. PMID:38739260. |
ag nps also upregulated the hepatic and renal genes involved in inflammation such as the interleukin-6 (il-6) and tumor necrosis factor-α (tnf-α), nuclear factor kappa b (nf-κβ), apoptosis such as the bcl2 associated x (bax), casp3, and other related to metabolism including asparagine synthetase (asns), suppressor of cytokine signaling 3 (socs3), myc proto-oncogene (myc), and c-c motif chemokine ligand 2 (ccl2). |
2024-05-13 |
2024-05-27 |
human |
| Shuqing Dong, Yuqi Huang, Hanrong Yan, Huarong Tan, Liying Fan, Minghao Chao, Yiping Ren, Ming Guan, Jiaxin Zhang, Zhao Liu, Fenglei Ga. Ternary heterostructure-driven photoinduced electron-hole separation enhanced oxidative stress for triple-negative breast cancer therapy. Journal of nanobiotechnology. vol 22. issue 1. 2024-05-12. PMID:38735931. |
zinc oxide nanoparticles (zno nps) stand as among the most significant metal oxide nanoparticles in trigger the formation of reactive oxygen species (ros) and induce apoptosis. |
2024-05-12 |
2024-05-27 |
Not clear |