| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lisi Qi, Yuanyuan Guo, Jingjing Luan, Dianrui Zhang, Zhongxi Zhao, Yuxia Lua. Folate-modified bexarotene-loaded bovine serum albumin nanoparticles as a promising tumor-targeting delivery system. Journal of materials chemistry. B. vol 2. issue 47. 2020-04-08. PMID:32262006. |
the in vitro cytotoxicity, cell apoptosis and cellular uptake experiments of the nanoparticles were performed by mtt assay, propidium iodide staining, fluorescence microscopy and flow cytometric analysis on a549 and mcf-7 cancer cells. |
2020-04-08 |
2023-08-13 |
cattle |
| V S Shaniba, Ahlam Abdul Aziz, P R Jayasree, P R Manish Kuma. Manilkara zapota (L.) P. Royen Leaf Extract Derived Silver Nanoparticles Induce Apoptosis in Human Colorectal Carcinoma Cells Without Affecting Human Lymphocytes or Erythrocytes. Biological trace element research. vol 192. issue 2. 2020-04-07. PMID:30850949. |
their cellular effects were assessed by mtt assay, fluorescence, and scanning electron microscopy of cells stained with propidium iodide, acridine orange/ethidium bromide, and annexin v-fitc to visualize signs of apoptosis. |
2020-04-07 |
2023-08-13 |
human |
| Xiaowei Xing, Shuang Guo, Guanghao Zhang, Yusheng Liu, Shaojie Bi, Xin Wang, Qinghua L. miR-26a-5p protects against myocardial ischemia/reperfusion injury by regulating the PTEN/PI3K/AKT signaling pathway. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 53. issue 2. 2020-04-07. PMID:31994603. |
in addition, the viability and apoptosis of cardiomyocytes were separately detected by mtt and flow cytometry. |
2020-04-07 |
2023-08-13 |
mouse |
| Xunan Zhang, Wei Zong, Wenlong Cheng, Xiaojun Ha. Codelivery of doxorubicin and sodium tanshinone IIA sulfonate using multicompartmentalized vesosomes to enhance synergism and prevent doxorubicin-induced cardiomyocyte apoptosis. Journal of materials chemistry. B. vol 6. issue 32. 2020-04-07. PMID:32254761. |
mtt (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay and western blotting analysis demonstrated that the mcv can enhance the synergistic effect of the drug combination and promote the protection of sts in dox-induced cardiomyocyte apoptosis. |
2020-04-07 |
2023-08-13 |
Not clear |
| Hui Peng, Ya-Bin Sun, Ji-Long Hao, Cheng-Wei Lu, Ming-Chao Bi, E Son. Neuroprotective effects of overexpressed microRNA-200a on activation of glaucoma-related retinal glial cells and apoptosis of ganglion cells via downregulating FGF7-mediated MAPK signaling pathway. Cellular signalling. vol 54. 2020-04-06. PMID:30439502. |
glaucoma-related parameters including the expression of cd11b and inos, activation of muller cells, and apoptosis of retinal ganglion cells (rgcs) in the mouse model were measured by immunohistochemistry, mtt assay and tunel assay, respectively. |
2020-04-06 |
2023-08-13 |
mouse |
| Hongxia Xiao, Zhen Li. Effects of microRNA‑217 on high glucose‑induced inflammation and apoptosis of human retinal pigment epithelial cells (ARPE‑19) and its underlying mechanism. Molecular medicine reports. vol 20. issue 6. 2020-04-06. PMID:31702814. |
an mtt assay revealed that mir‑217 inhibitor significantly increased the viability and decreased the apoptosis of high glucose‑induced arpe‑19 cells. |
2020-04-06 |
2023-08-13 |
human |
| S L Xie, M Wang, X H Du, Z W Zhao, G Y L. [miR-455 Inhibits HepG2 Cell Proliferation and Promotes Apoptosis by Targeting RhoC]. Molekuliarnaia biologiia. vol 54. issue 1. 2020-04-06. PMID:32163390. |
therefore, in the present study, the role of mir-455 was analyzed in hepg2 cells proliferation and apoptosis using mtt and flow cytometry methods. |
2020-04-06 |
2023-08-13 |
Not clear |
| Yanxia Guo, Yuxiu Jia, Shikang Wang, Ning Liu, Dongfang Gao, Lu Zhang, Zhaomin Lin, Shuling Wang, Feng Kong, Chuanliang Peng, Yongqing Li. Downregulation of MUTYH contributes to cisplatin‑resistance of esophageal squamous cell carcinoma cells by promoting Twist‑mediated EMT. Oncology reports. vol 42. issue 6. 2020-04-03. PMID:31578574. |
ectopic expression of mutyh by transient transfection of pcdna3.1‑mutyh plasmid significantly enhanced the cddp‑mediated inhibitory effect on resistant cell proliferation and induction of apoptosis, while silencing of mutyh by transiently transfecting mutyh‑targeted sirna in parental cells led to decreased sensitivity to cddp as demonstrated by mtt assay, suggesting the crucial involvement of mutyh in cddp resistance. |
2020-04-03 |
2023-08-13 |
Not clear |
| Ying Ye, Ya-Nan Song, Sai-Fei He, Ju-Hua Zhuang, Guo-Yu Wang, Wei Xi. GINS2 promotes cell proliferation and inhibits cell apoptosis in thyroid cancer by regulating CITED2 and LOXL2. Cancer gene therapy. vol 26. issue 3-4. 2020-04-02. PMID:30177819. |
the abilities of proliferation and apoptosis, and cell cycle were determined by mtt assay and flow cytometric assay. |
2020-04-02 |
2023-08-13 |
mouse |
| Soheyla Yadamani, Ali Neamati, Masoud Homayouni-Tabrizi, Samira Yadamani, Afsaneh Javdani-Mallak, S Ali Beyramabad. Anticancer Activities of Cu(II) Complex-Schiff Base and Low-Frequency Electromagnetic Fields and the Interaction Between Cu(II) Complex-Schiff Base with Bovine Serum Albumin by Spectroscopy. Applied biochemistry and biotechnology. vol 190. issue 3. 2020-04-02. PMID:31650355. |
in this project, antiproliferative activity on breast cancer cells was tested by tubo cells using mtt assay and apoptosis properties were studied by flow cytometry. |
2020-04-02 |
2023-08-13 |
mouse |
| Nisha Yadav, Jacinth Rajendra, Anagha Acharekar, Shilpee Dutt, Pradeep Vavi. Effect of Glucosamine Conjugate-Functionalized Liposomes on Glioma Cell and Healthy Brain: An Insight for Future Application in Brain Infusion. AAPS PharmSciTech. vol 21. issue 1. 2020-04-02. PMID:31845106. |
the study revealed a significant effect on cytotoxicity and apoptosis in vitro as assessed on grade iv-resistant glioma cell lines, sf268, u87mg, using mtt assay and pi staining. |
2020-04-02 |
2023-08-13 |
human |
| Hua-Chao Yang, Jun-Yi Wang, Xing-Yao Bu, Bin Yang, Bang-Qing Wang, Sen Hu, Zhao-Yue Yan, Yu-Shuai Gao, Shuang-Yin Han, Ming-Qi Q. Resveratrol restores sensitivity of glioma cells to temozolamide through inhibiting the activation of Wnt signaling pathway. Journal of cellular physiology. vol 234. issue 5. 2020-03-30. PMID:30317578. |
cell survival rate and inhibitory concentration at half maximum value were detected by mtt, apoptosis by flow cytometry, and terminal deoxynucleotidyl transferase-mediated dutp nick-end labeling staining, in vitro proliferation by hanging drop method and β-catenin translocation into nuclei by top/fop-flash assay. |
2020-03-30 |
2023-08-13 |
mouse |
| Qing Gao, Lin Xu, Qian Yang, Tian-Jun Gua. MicroRNA-21 contributes to high glucose-induced fibrosis in peritoneal mesothelial cells in rat models by activation of the Ras-MAPK signaling pathway via Sprouty-1. Journal of cellular physiology. vol 234. issue 5. 2020-03-30. PMID:30515805. |
mtt assay and flow cytometry were conducted to observe the cell viability and cell apoptosis of peritoneal mesothelial cells. |
2020-03-30 |
2023-08-13 |
rat |
| S Mehdi Ebrahimi, S Zahra Bathaie, Nassim Faridi, Mohammad Taghikhani, Manouchehr Nakhjavani, Soghrat Faghihzade. L-lysine protects C2C12 myotubes and 3T3-L1 adipocytes against high glucose damages and stresses. PloS one. vol 14. issue 12. 2020-03-30. PMID:31856203. |
to investigate the role of hg and/or lys on cell apoptosis, oxidative status, unfolded protein response (upr) and autophagy, we used the mtt assay and flow cytometry, spectrophotometry and fluorometry, rt-pcr and western blotting, respectively. |
2020-03-30 |
2023-08-13 |
rat |
| Zhiyuan Zhu, Pingde Zhang, Ning Li, Karrie Mei Yee Kiang, Stephen Yin Cheng, Vincent Kam-Wai Wong, Gilberto Ka-Kit Leun. Lovastatin Enhances Cytotoxicity of Temozolomide via Impairing Autophagic Flux in Glioblastoma Cells. BioMed research international. vol 2019. 2020-03-25. PMID:31662972. |
cytotoxicity was measured by mtt and colony formation assays; apoptosis was measured by flow cytometry; the cellular autophagic function was detected by the egfp-mrfp-lc3 reporter and western blot assay. |
2020-03-25 |
2023-08-13 |
Not clear |
| Jinghua Jiao, Yuheng Wang, Xiaofeng Sun, Xiaojing Jian. Midazolam induces A549 cell apoptosis International journal of clinical and experimental pathology. vol 11. issue 3. 2020-03-25. PMID:31938232. |
apoptosis of the nsclc cells in response to midazolam was determined by mtt assay, flow cytometry, and western blot. |
2020-03-25 |
2023-08-13 |
Not clear |
| Yihan Wang, Leo M Hall, Marisa Kujawa, Hainan Li, Xiang Zhang, Megan O'Meara, Tomomi Ichinose, Jie-Mei Wan. Methylglyoxal triggers human aortic endothelial cell dysfunction via modulation of the K American journal of physiology. Cell physiology. vol 317. issue 1. 2020-03-23. PMID:30995106. |
d-haecs demonstrated impaired network formation (on matrigel) and proliferation (mtt assay), as well as increased apoptosis (caspase-3/7 activity and tunel staining), compared with h-haecs. |
2020-03-23 |
2023-08-13 |
human |
| Otilia Ruxandra Vasile, Ecaterina Andronescu, Roxana Truşcă, Eugeniu Vasile, Alina Maria Holban, Mariana Carmen Chifiriuc, Florin Iordache, Horia Maniu, Coralia Bleotu, Ioana Andreea Neacşu, Bogdan Ştefan Vasil. Structure-grain size-synthesis route of silver nanoparticles: a correlation with the cytotoxic effect. Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie. vol 60. issue 2. 2020-03-23. PMID:31658336. |
their cytotoxicity was evaluated based on their influence on cellular morphology and proliferation rate, cell cycle and apoptosis of undifferential stem cells, endothelial cells and tumoral cells, assessed through flow cytometry, cloning and mtt assay. |
2020-03-23 |
2023-08-13 |
Not clear |
| Qingyang Zhao, Weiwei Chang, Rui Chen, Yanhong Li. Anti-Proliferative Effect of Wogonin on Ovary Cancer Cells Involves Activation of Apoptosis and Cell Cycle Arrest. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2020-03-23. PMID:31707402. |
material and methods cell viability changes and apoptosis induction by wogonin were assessed by mtt (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenytetrazolium bromide) assay and fluorescence microscopy. |
2020-03-23 |
2023-08-13 |
Not clear |
| Jun Lu, Nina Zhou, Ping Yang, Lanqiuzi Deng, Ganzhe Li. MicroRNA-27a-3p Downregulation Inhibits Inflammatory Response and Hippocampal Neuronal Cell Apoptosis by Upregulating Mitogen-Activated Protein Kinase 4 (MAP2K4) Expression in Epilepsy: In Vivo and In Vitro Studies. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2020-03-23. PMID:31710596. |
cell viability and cell apoptosis were analyzed by 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-h-tetrazolium bromide (mtt) assay and flow cytometry. |
2020-03-23 |
2023-08-13 |
rat |