| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yuan Zhao, Gao-Yin Kong, Wan-Min Pei, Bo Zhou, Qin-Qin Zhang, Bing-Bing Pa. Dexmedetomidine alleviates hepatic injury via the inhibition of oxidative stress and activation of the Nrf2/HO-1 signaling pathway. European cytokine network. vol 30. issue 3. 2020-05-18. PMID:31957703. |
mtt assay and flow cytometry analysis were used to determine the influence of dex on cell viability and cell apoptosis. |
2020-05-18 |
2023-08-13 |
Not clear |
| Jin-Shan Xing, Xun Wang, Yu-Long Lan, Jia-Cheng Lou, Binbin Ma, Tingzhun Zhu, Hongqiang Zhang, Dongsheng Wang, Zhikuan Yu, Zhongbo Yuan, Xin-Yu Li, Bo Zhan. Isoalantolactone inhibits IKKβ kinase activity to interrupt the NF-κB/COX-2-mediated signaling cascade and induces apoptosis regulated by the mitochondrial translocation of cofilin in glioblastoma. Cancer medicine. vol 8. issue 4. 2020-05-15. PMID:30740911. |
in the current study, the biological functions of iatl were examined by mtt, cell migration, colony formation, and cell apoptosis assays. |
2020-05-15 |
2023-08-13 |
mouse |
| Weiling Xu, Peihong Gao, Yan Zhang, Li Piao, Dong Don. microRNA-138 induces cell survival and reduces WNT/β-catenin signaling of osteoarthritis chondrocytes through NEK2. IUBMB life. vol 71. issue 9. 2020-05-15. PMID:31034758. |
the 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2h-tetrazolium bromide (mtt) assay and flow cytometry were employed to detect cell proliferation and apoptosis, respectively. |
2020-05-15 |
2023-08-13 |
mouse |
| Lingling Yuan, Xingwu Duan, Runtian Zhang, Yunbi Zhang, Muwen Q. Aloe polysaccharide protects skin cells from UVB irradiation through Keap1/Nrf2/ARE signal pathway. The Journal of dermatological treatment. vol 31. issue 3. 2020-05-12. PMID:30897007. |
the cell viability was detected by mtt assay, and cell apoptosis was detected by tunel (tdt-mediated dutp nick-end labeling) and annexin-v/pi assay, and cell-cycle status in different groups were observed via flow cytometry (fcm). |
2020-05-12 |
2023-08-13 |
mouse |
| Jiying Wang, Zhaoying Sheng, Yong Ca. Effects of microRNA-513b on cell proliferation, apoptosis, invasion, and migration by targeting HMGB3 through regulation of mTOR signaling pathway in non-small-cell lung cancer. Journal of cellular physiology. vol 234. issue 7. 2020-05-11. PMID:30623409. |
then, mir-513b was overexpressed in nsclc cell, and the proliferation, migration, invasion, and apoptosis of cells were determined by 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2h-tetrazolium bromide (mtt), wound healing, transwell, and flow cytometry, respectively. |
2020-05-11 |
2023-08-13 |
Not clear |
| Mohammad Javad Sohrabi, Ahmad-Reza Dehpour, Farnoosh Attar, Anwarul Hasan, Nahid Mohammad-Sadeghi, Ali Akbar Meratan, Falah Mohammad Aziz, Abbas Salihi, Mudhir Sabir Shekha, Keivan Akhtari, Koorosh Shahpasand, Seyed Mohammad Masood Hojjati, Majid Sharifi, Ali Akbar Saboury, Seyed Mahdi Rezayat, Seyyedeh Elaheh Mousavi, Mojtaba Falahat. Silymarin-albumin nanoplex: Preparation and its potential application as an antioxidant in nervous system in vitro and in vivo. International journal of pharmaceutics. vol 572. 2020-05-05. PMID:31715345. |
afterwards, their protective effect against lps (20 µg/ml) -induced toxicity in sh-sy5y cells was investigated by mtt, ros, and apoptosis assays. |
2020-05-05 |
2023-08-13 |
rat |
| Yafeng Shang, Yanjie Kang, Jiantao Sun, Pengtao Wei, Jinhui Yang, Han Zhan. MiR-145-modulated SOX9-mediated hypospadias through acting on mitogen-activated protein kinase signaling pathway. Journal of cellular physiology. vol 234. issue 7. 2020-05-04. PMID:30565690. |
furthermore, the apoptosis, proliferation, and viability of cells were evaluated by means of flow cytometry, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) and colony formation assays. |
2020-05-04 |
2023-08-13 |
rat |
| X Qin, X Y Wang, J W Fei, F H Li, J Han, H X Wan. MiR-20a promotes lung tumorigenesis by targeting RUNX3 via TGF-β signaling pathway. Journal of biological regulators and homeostatic agents. vol 34. issue 2. 2020-04-29. PMID:32347076. |
the analysis of cell growth and apoptosis were performed by mtt, xenograft models, western blot assays. |
2020-04-29 |
2023-08-13 |
human |
| Xue-Lian Zhang, Bai-Fu An, Guang-Cheng Zhan. MiR-27 alleviates myocardial cell damage induced by hypoxia/reoxygenation via targeting TGFBR1 and inhibiting NF-κB pathway. The Kaohsiung journal of medical sciences. vol 35. issue 10. 2020-04-27. PMID:31169351. |
then the cell proliferation was tested by mtt assay and the cell apoptosis was detected by flow cytometry. |
2020-04-27 |
2023-08-13 |
Not clear |
| Jun Zhou, Liang Xia, Yu Zhan. Naringin inhibits thyroid cancer cell proliferation and induces cell apoptosis through repressing PI3K/AKT pathway. Pathology, research and practice. vol 215. issue 12. 2020-04-27. PMID:31727500. |
then, cell proliferation was determined using 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-h-tetrazolium bromide (mtt) assay, and cell apoptosis was analyzed by flow cytometer. |
2020-04-27 |
2023-08-13 |
Not clear |
| Xiaomeng Liu, Yuanyuan Zhang, Hongwei Liang, Yusong Zhang, Yanchao X. microRNA-499-3p inhibits proliferation and promotes apoptosis of retinal cells in diabetic retinopathy through activation of the TLR4 signaling pathway by targeting IFNA2. Gene. vol 741. 2020-04-24. PMID:32160960. |
gain- and loss-of-function assays were performed to explore the functional roles of aberrantly expressed mir-499-3p and ifna2 in retinal cell proliferation by mtt, and apoptosis by flow cytometry. |
2020-04-24 |
2023-08-13 |
rat |
| Jalal Choupani, Mohammad R Alivand, Sima M Derakhshan, Mohammad Zaeifizadeh, Mahmoud S Khanian. Oleuropein inhibits migration ability through suppression of epithelial-mesenchymal transition and synergistically enhances doxorubicin-mediated apoptosis in MCF-7 cells. Journal of cellular physiology. vol 234. issue 6. 2020-04-20. PMID:30317622. |
the cytotoxic effect of oleu and dox was assessed by mtt assay, whereas the ratio of apoptosis was investigated by flow cytometry. |
2020-04-20 |
2023-08-13 |
Not clear |
| Jingping Lu, Jinjun Shan, Ning Liu, Yao Ding, Pei Wan. Tanshinone IIA Can Inhibit Angiotensin II-Induced Proliferation and Autophagy of Vascular Smooth Muscle Cells via Regulating the MAPK Signaling Pathway. Biological & pharmaceutical bulletin. vol 42. issue 11. 2020-04-16. PMID:31391347. |
vsmcs were treated with ang ii with or without tanshinone iia (1, 5 and 10 µg/ml), and the proliferation, apoptosis in cells with different treatment were examined by methylthiazolyl tetrazolium (mtt) and flow cytometry methods. |
2020-04-16 |
2023-08-13 |
Not clear |
| Lin-Juan Tian, Yun-Ping Wu, Dong Wang, Zhi-He Zhou, Shou-Bin Xue, Dong-Yue Zhang, Yong-Gang Wei, Wei Li. Upregulation of Long Noncoding RNA (lncRNA) X-Inactive Specific Transcript (XIST) is Associated with Cisplatin Resistance in Non-Small Cell Lung Cancer (NSCLC) by Downregulating MicroRNA-144-3p. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2020-04-15. PMID:31659146. |
the mtt assay measured cell survival and proliferation, a transwell assay evaluated cell migration, and flow cytometry measured apoptosis. |
2020-04-15 |
2023-08-13 |
mouse |
| Zi-Jian Yang, Jun-Yao Huang, Ye-Fei Gao, Jun-Yao Huang, Wen-Ji Huang, Jun-Yao Huang, Shi-Lei Xu, Jun-Yao Huang, Jing-Jing Jin, Jun-Yao Huang, Ye-Dong Wan, Jun-Yao Huang, Ming Yan, Jun-Yao Huang, Hong-Jiao Mao, Jun-Yao Huang, Yun Zhang, Jun-Yao Huan. [Effects of bergapten on damages of osteocytes MLO-Y4 induced by TCP wear particles and its mechanism]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 35. issue 6. 2020-04-14. PMID:32239867. |
mtt assay and calcein-am staining were used to determine the viability of mlo-y4 cells; hoechst 33342 staining and the flow cytometry were applied to detect the apoptosis of mlo-y4; real-time pcr was performed to examine the mrna levels of dentin matrix protein1 (dmp-1), sclerostin (sost) and fibroblast growth factor23 (fgf23); western blot was performed to examine protein expressions of glucose-regulated protein 78 (grp78), protein kinase r-like er kinase (perk) phospho-perk (p-perk), eukaryotic initiation factor 2α (eif2α), phospho-eif2α (p-eif2α), activating transcription factor 4 (aft4), c/ebp homologous protein (chop) and caspase-3 in mlo-y4 cells. |
2020-04-14 |
2023-08-13 |
Not clear |
| Ling Huang, Yuanyuan Li, Chunhui Wang, Na Li, Yue Hou, Ruijing Chang, Man Sun, Ruochen Wang, Lei Zhu, Chong Qia. Overexpression of Collapsin Response Mediator Protein 1 Inhibits Human Trophoblast Cells Proliferation, Migration, and Invasion. Reproductive sciences (Thousand Oaks, Calif.). vol 26. issue 7. 2020-04-13. PMID:30466368. |
in this study, we found an inhibitory effect of crmp-1 on proliferation, migration, invasion, and an enhanced effect on apoptosis in human trophoblast cell lines htr-8/svneo and jeg-3 by mtt assay, colony formation assay, cell viability assay, caspase 3/7 activity assay, scratch wound assay, and matrigel transwell assay. |
2020-04-13 |
2023-08-13 |
human |
| Jun Lin, Juan Shen, Hao Yue, Zhongwei Ca. miRNA‑183‑5p.1 promotes the migration and invasion of gastric cancer AGS cells by targeting TPM1. Oncology reports. vol 42. issue 6. 2020-04-13. PMID:31638242. |
cell viability, apoptosis and related proteins were detected by mtt assay, flow cytometry, immunofluorescence and western blotting, respectively. |
2020-04-13 |
2023-08-13 |
Not clear |
| Shulei Gong, Xiaohan Qu, Shize Yang, Siyu Zhou, Peiwen Li, Qigang Zhan. RFC3 induces epithelial‑mesenchymal transition in lung adenocarcinoma cells through the Wnt/β‑catenin pathway and possesses prognostic value in lung adenocarcinoma. International journal of molecular medicine. vol 44. issue 6. 2020-04-13. PMID:31661124. |
in addition, the proliferation, cell cycle distribution and apoptosis of a549 and h1299 cells were determined by mtt assay and flow cytometry, respectively, following cell transfection to induce overexpression and knockdown of rfc3. |
2020-04-13 |
2023-08-13 |
Not clear |
| Chuanzhen Liu, Mengmeng Tang, Xiquan Zhang, Jianhua Li, Guangqing Ca. Knockdown of miR-665 Protects Against Cardiomyocyte Ischemia/Reperfusion Injury-Induced ROS Accumulation and Apoptosis Through the Activation of Pak1/Akt Signaling in Myocardial Infarction. International heart journal. vol 61. issue 2. 2020-04-08. PMID:32132320. |
moreover, cell viability and apoptosis were detected by mtt assay, tdt-mediated dutp nick end labeling (tunel), and pi/fitc-annexin v assay. |
2020-04-08 |
2023-08-13 |
rat |
| Yan Zhang, Jianjing Liu, Yutong Fu, Ke Tan, Zhaoyang Ye, Meidong Lan. Self-assembly of polyion complex nanocarriers from ammonium glycyrrhizinate and monomethoxy poly(ethylene glycol)-b-poly(γ-amino-ε-caprolactone). Journal of materials chemistry. B. vol 1. issue 11. 2020-04-08. PMID:32260724. |
results obtained by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (mtt) assay, flow cytometry and fluorescence microscopy revealed that amg loaded nanoparticles demonstrated greater prevention of liver cell apoptosis induced by lipopolysaccharide (lps). |
2020-04-08 |
2023-08-13 |
Not clear |