| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mohd Mughees, Mohd Samim, Yadhu Sharma, Saima Waji. Identification of protein targets and the mechanism of the cytotoxic action of Ipomoea turpethum extract loaded nanoparticles against breast cancer cells. Journal of materials chemistry. B. vol 7. issue 39. 2020-08-20. PMID:31549130. |
root extract, was loaded on the nanoparticles and the cytotoxicity was evaluated in breast cancer cell lines (mcf-7 and mda-mb-231) by various cytotoxic assays like mtt assay, cfse cell proliferation assay, apoptosis assay, cell cycle study and dapi nuclear staining. |
2020-08-20 |
2023-08-13 |
Not clear |
| Hongping Cheng, Anshoo Malhotr. Evaluation of Potential of Long Noncoding RNA NEAT1 in Colorectal Cancer. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. vol 39. issue 2. 2020-08-20. PMID:32749120. |
cell proliferation and apoptosis were measured by 3-(4,5-dimethylthiazole-2-y1)-2,5-diphenyl tetrazolium bromide (mtt) assay and flow cytometry. |
2020-08-20 |
2023-08-13 |
Not clear |
| P Cheng, P Lu, J Guan, Y Zhou, L Zou, X Yi, H Chen. LncRNA KCNQ1OT1 controls cell proliferation, differentiation and apoptosis by sponging miR-326 to regulate c-Myc expression in acute myeloid leukemia. Neoplasma. vol 67. issue 2. 2020-08-17. PMID:31390869. |
cell proliferation, apoptosis and differentiation were measured by mtt assay, flow cytometry and qrt-pcr, respectively. |
2020-08-17 |
2023-08-13 |
Not clear |
| W L Lv, Y Y Hu, Z N Li, W Zhang, Q Pa. PAX3 silencing suppresses gastric cancer proliferation and angiogenesis via MET/PI3K signaling. Neoplasma. vol 67. issue 2. 2020-08-17. PMID:31847528. |
the proliferation, apoptosis and angiogenesis of gastric cancer cells were assessed using mtt assay, flow cytometry and in vitro tube formation assay. |
2020-08-17 |
2023-08-13 |
mouse |
| Xue Li, Caiwen Wei, Zhaozhi Zhang, Qu Jin, Xue Xia. MiR-134-5p Regulates Myocardial Apoptosis and Angiogenesis by Directly Targeting KDM2A After Myocardial Infarction. International heart journal. vol 61. issue 4. 2020-08-12. PMID:32684588. |
the influence of mir-134-5p on cardiomyocytes apoptosis was detected using methyl thiazolyl tetrazolium (mtt) assay. |
2020-08-12 |
2023-08-13 |
mouse |
| Jianteng Wei, Linghao Zhang, Jianfei Liu, Dong Pei, Ningli Wang, Han Wang, Duolong Di, Yewei Li. Protective effect of Lycium barbarum polysaccharide on ethanol-induced injury in human hepatocyte and its mechanism. Journal of food biochemistry. 2020-08-03. PMID:32744344. |
the cell survival rate, the apoptosis rate, and the intracellular ros level was detected by mtt assay, flow cytometry, laser confocal microscopy, and fluorescence spectrophotometry, respectively. |
2020-08-03 |
2023-08-13 |
human |
| Yu Pan, Andong Zhao, Zhiqiang Zhong, Xiaohua Pan, Sa Ca. Ganoderma spore lipid protects mouse bone marrow mesenchymal stem cells and hematopoiesis from the cytotoxicity of the chemotherapeutic agent. Biotechnology progress. vol 35. issue 5. 2020-07-29. PMID:31207156. |
mtt and annexin v/propidium iodide (pi) analyses found that gsl pre-treatment and co-treatment increased the proliferation and decreased the apoptosis in ctx-treated mscs. |
2020-07-29 |
2023-08-13 |
mouse |
| Qianyuan Li, Xiukou Zhou, Zhengyu Fang, Huamiao Zho. Knockdown of KLK12 inhibits viability and induces apoptosis in human colorectal cancer HT-29 cell line. International journal of molecular medicine. vol 44. issue 5. 2020-07-27. PMID:31485623. |
cell viability, migration, invasion and apoptosis were detected by mtt, wound healing, transwell and flow cytometry assays, respectively. |
2020-07-27 |
2023-08-13 |
human |
| Mengying Wang, Zhengzheng Li, Meng Zhang, Hui Wang, Ying Zhang, Yiping Feng, Yinan Liu, Jinghong Che. Decorin knockdown affects the gene expression profile of adhesion, growth and extracellular matrix metabolism in C-28/I2 chondrocytes. PloS one. vol 15. issue 4. 2020-07-27. PMID:32353084. |
mtt, adhesion assays and flow cytometry were used to investigate the effect of decorin knockdown on cell proliferation, adhesion, and apoptosis. |
2020-07-27 |
2023-08-13 |
human |
| Yan Wen, Guohui Liu, Yun Zhang, Hai L. MicroRNA-205 is associated with diabetes mellitus-induced erectile dysfunction via down-regulating the androgen receptor. Journal of cellular and molecular medicine. vol 23. issue 5. 2020-07-24. PMID:30729682. |
meanwhile, the effects of mir-205 and ar on cell proliferation and apoptosis were evaluated using mtt assay and flow cytometry respectively. |
2020-07-24 |
2023-08-13 |
rat |
| Zhengfei Shan, Yongwei Li, Shengqiang Yu, Jitao Wu, Chengjun Zhang, Yue Ma, Guimin Zhuang, Jiantao Wang, Zhenli Gao, Dongfu Li. CTCF regulates the FoxO signaling pathway to affect the progression of prostate cancer. Journal of cellular and molecular medicine. vol 23. issue 5. 2020-07-24. PMID:30873749. |
the rates of cell proliferation, cell invasion and apoptosis were examined by mtt assay, cell invasion assay and flow cytometry under different interference conditions. |
2020-07-24 |
2023-08-13 |
mouse |
| Z Ma, D F J Ketelhuth, T Wirström, T Ohki, M J Forteza, H Wang, V Grill, C B Wollheim, A Björklun. Increased uptake of oxLDL does not exert lipotoxic effects in insulin-secreting cells. Journal of molecular endocrinology. vol 62. issue 4. 2020-07-20. PMID:30917339. |
exposure to concentrations of oxldl from 20 to 100 µg/ml dose-dependently increased toxicity (evaluated by mtt) as well as apoptosis. |
2020-07-20 |
2023-08-13 |
mouse |
| Yichen Jin, Ru Huang, Yanfu Xia, Chen Huang, Feng Qiu, Jinxian Pu, Xuefeng He, Xiaojun Zha. Long Noncoding RNA DNA and cell biology. vol 39. issue 7. 2020-07-20. PMID:32343913. |
mtt and tunel experiments were used to show cell viability and apoptosis, respectively. |
2020-07-20 |
2023-08-13 |
Not clear |
| Elahe Seyed Hosseini, Marziyeh Alizadeh Zarei, Sadegh Babashah, Roohollah Nakhaei Sistani, Majid Sadeghizadeh, Hamad Haddad Kashani, Javad Amini Mahabadi, Fatemeh Izadpanah, Mohhamad Ali Atlasi, Hossein Nikza. Studies on combination of oxaliplatin and dendrosomal nanocurcumin on proliferation, apoptosis induction, and long non-coding RNA expression in ovarian cancer cells. Cell biology and toxicology. vol 35. issue 3. 2020-07-16. PMID:30478652. |
the aim of this study was to determine the effects of dendrosomal nanocurcumin (dnc) and oxaliplatin (oxa) and their combination on cell death and apoptosis induction in human ovarian carcinoma cell lines analyzed by mtt assay and flow cytometry, respectively. |
2020-07-16 |
2023-08-13 |
human |
| Mai M Elkeiy, Abeer A Khamis, Mona M El-Gamal, Maha M Abo Gazia, Zeinb A Zalat, Mohammed A El-Mag. Chitosan nanoparticles from Artemia salina inhibit progression of hepatocellular carcinoma in vitro and in vivo. Environmental science and pollution research international. vol 27. issue 16. 2020-07-10. PMID:30293105. |
administration of cnps decreased hcc progression as evidenced by (1) induced hepg2 cell death as detected by mtt assay; (2) induced necrosis as indicated by acridine orange/propidium iodide (ao/pi) red staining, annexin v/7-aad positive staining (detected by flow cytometry), and upregulated expression of necrosis markers (parp1 and its downstream target, rip1 genes), but no effect on apoptosis as revealed by insignificant changes in caspase 3 activity and mrna levels of bax and aif; (3) increased intracellular ros and decreased mitochondrial membrane potential in hepg2; (4) decreased liver relative weight, serum levels of liver enzymes (alt, ast, and alp), total bilirubin, and cancer markers (afp and ggt), number and area of gst-p positive tumor nodules; and (5) reduced oxidative stress (decrease in mda levels) and increased activities of sod, cat, and gpx enzymes in rat liver. |
2020-07-10 |
2023-08-13 |
rat |
| Peng Li, Zhiwei Xiao, Jiajun Luo, Yaojun Zhang, Lizhu Li. MiR-139-5p, miR-940 and miR-193a-5p inhibit the growth of hepatocellular carcinoma by targeting SPOCK1. Journal of cellular and molecular medicine. vol 23. issue 4. 2020-07-10. PMID:30710422. |
through 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-h-tetrazolium bromide,thiazolyl blue tetrazolium bromide (mtt) and transwell assays and flow cytometry, hcc cell viability, invasion and apoptosis were determined. |
2020-07-10 |
2023-08-13 |
mouse |
| Mehran Nazarparvar-Noshadi, Jafar Ezzati Nazhad Dolatabadi, Yahya Rasoulzadeh, Yousef Mohammadian, Dariush Shanehband. Apoptosis and DNA damage induced by silica nanoparticles and formaldehyde in human lung epithelial cells. Environmental science and pollution research international. vol 27. issue 15. 2020-07-10. PMID:32198691. |
the cells were exposed to snps and fa separately and in combined form and the single and combined toxicity of snps and fa were evaluated by focusing on cellular viability, dna damage, and apoptosis via mtt, dapi staining, dna ladder, and annexin v-fitc apoptosis assays. |
2020-07-10 |
2023-08-13 |
human |
| Yan Wu, Li Xu, Jiwen Qian, Leilei Shi, Yue Su, Youfu Wang, Dawei Li, Xinyuan Zh. Methotrexate-Mn Biomaterials science. vol 8. issue 2. 2020-07-07. PMID:31777869. |
then we confirmed that the antitumor ability was mediated by mtx through mtt and cell apoptosis assay in vitro. |
2020-07-07 |
2023-08-13 |
Not clear |
| Xingzhen Zhang, Lixia Zhao, Guangxi Zhai, Jianbo Ji, Anchang Li. Multifunctional Polyethylene Glycol (PEG)-Poly (Lactic-Co-Glycolic Acid) (PLGA)-Based Nanoparticles Loading Doxorubicin and Tetrahydrocurcumin for Combined Chemoradiotherapy of Glioma. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2020-06-26. PMID:31856143. |
the in vitro mtt, apoptosis, and clone formation assays were performed to detect the proliferation and radiosensitivity of cells with various treatments. |
2020-06-26 |
2023-08-13 |
mouse |
| Xingzhen Zhang, Lixia Zhao, Guangxi Zhai, Jianbo Ji, Anchang Li. Multifunctional Polyethylene Glycol (PEG)-Poly (Lactic-Co-Glycolic Acid) (PLGA)-Based Nanoparticles Loading Doxorubicin and Tetrahydrocurcumin for Combined Chemoradiotherapy of Glioma. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2020-06-26. PMID:31856143. |
mtt, apoptosis, and clone formation assays revealed the enhanced anti-cancer activity and favorable radiosensitizing effect of tf-nps-dox-thc. |
2020-06-26 |
2023-08-13 |
mouse |