| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lei Wang, Mingxin Yu, Shanshan Zha. lncRNA MEG3 modified epithelial-mesenchymal transition of ovarian cancer cells by sponging miR-219a-5p and regulating EGFR. Journal of cellular biochemistry. vol 120. issue 10. 2020-09-09. PMID:31161607. |
moreover, pcdna3.1-meg3, si-meg3, mir-219a-5p mimic, mir-219a-5p inhibitor, pcdna3.1-egfr, and si-egfr were, respectively, transfected into the oc cells, and their impacts on viability, proliferation, apoptosis, invasion, and migration of oc cells were assessed via conduction of mtt assay, colony formation assay, flow cytometry assay, transwell assay, and scratch assay. |
2020-09-09 |
2023-08-13 |
human |
| Dan Yang, Meijuan Zhang, Yu Gan, Si Yang, Jinglei Wang, Mei Yu, Jie Wei, Jiaxiang Che. Involvement of oxidative stress in ZnO NPs-induced apoptosis and autophagy of mouse GC-1 spg cells. Ecotoxicology and environmental safety. vol 202. 2020-09-07. PMID:32800232. |
herein, mouse-derived spermatogonia cell line gc-1 spg cells were treated with zno nps for 24 h in the presence or absence of radical scavenger n-acetyl-l-cysteine (nac) or autophagy inhibitor 3-methyladenine (3-ma), then cell viability was observed by mtt assay; apoptosis was observed by western blotting analysis and annexinv-fitc/pi assay, respectively; autophagy was detected by western blotting analysis and transmission electron microscopy, respectively; and the contents of mda and gsh and the activities of sod and gsh-px were measured by oxidative stress kits. |
2020-09-07 |
2023-08-13 |
mouse |
| Yun Shi, Ya Su, Chuanli Liu, Jinglong Tao, Hao Fu, Chengzhi L. Inhibition of HES-1 might play a protective role in endothelial cells under cholesterol stimulation via PI3K/AKT signaling pathway. General physiology and biophysics. vol 39. issue 2. 2020-09-03. PMID:32329442. |
in this study, we established a cell model of hes-1 inhibition and overexpression in ea.hy 926 cells, and firstly detected the proliferation rete of ea.hy 926 cells under cholesterol stimulation using mtt assay, and apoptosis of ea.hy 926 cells were detected using flow cytometry. |
2020-09-03 |
2023-08-13 |
Not clear |
| Lili Zheng, Jing Huang, Yuan Su, Fang Wang, Hongfang Kong, Hong Xi. Overexpression of tissue factor pathway inhibitor 2 attenuates trophoblast proliferation and invasion in preeclampsia. Human cell. vol 33. issue 3. 2020-09-02. PMID:32130677. |
mtt assay, annexin v/propidium iodide (pi) apoptosis assay, and transwell assay were used to determine the cell proliferation, apoptosis, and invasion. |
2020-09-02 |
2023-08-13 |
Not clear |
| Daniela Carneiro de Lima, Silvana Vianna Rodrigues, Gilson Teles Boaventura, Hee-Yeon Cho, Thomas C Chen, Axel H Schönthal, Clovis Orlando Da Fonsec. Simultaneous measurement of perillyl alcohol and its metabolite perillic acid in plasma and lung after inhalational administration in Wistar rats. Drug testing and analysis. vol 12. issue 2. 2020-09-01. PMID:31800149. |
toxicity was established by a standard mtt assay, and apoptosis markers were analyzed by western blot. |
2020-09-01 |
2023-08-13 |
rat |
| Zheyu Zhang, Sifang Zhang, Jingjing Yang, Pengji Yi, Panpan Xu, Min Yi, Weijun Pen. Integrated transcriptomic and metabolomic analyses to characterize the anti-cancer effects of (-)-epigallocatechin-3-gallate in human colon cancer cells. Toxicology and applied pharmacology. vol 401. 2020-08-31. PMID:32512070. |
the mtt assay, flow cytometry, and tunel staining were used to study the underlying mechanisms of egcg (proliferation, apoptosis, autophagy). |
2020-08-31 |
2023-08-13 |
human |
| Xinyu Tang, Yang Li, Long Liu, Rui Guo, Ping Zhang, Yihe Zhang, Yong Zhang, Jia Zhao, Jing Su, Liankun Sun, Yanan Li. Sirtuin 3 induces apoptosis and necroptosis by regulating mutant p53 expression in small‑cell lung cancer. Oncology reports. vol 43. issue 2. 2020-08-21. PMID:31894331. |
light microscopy, mtt and flow cytometric assays revealed that sirt3 overexpression inhibited growth and promoted apoptosis in nci‑h446 human small cell lung cancer cells. |
2020-08-21 |
2023-08-13 |
human |
| Zhonghui Chen, Weibing Zhang, Nu Zhang, Yan Zhou, Geliang Hu, Mingdi Xue, Junhua Liu, Yaming L. Down-regulation of insulin-like growth factor binding protein 5 is involved in intervertebral disc degeneration via the ERK signalling pathway. Journal of cellular and molecular medicine. vol 23. issue 9. 2020-08-20. PMID:31290273. |
igfbp5 was shown to significantly promote np cell proliferation and inhibit apoptosis in vitro, which was confirmed by mtt, flow cytometry and colony formation assays. |
2020-08-20 |
2023-08-13 |
human |
| Mohd Mughees, Mohd Samim, Yadhu Sharma, Saima Waji. Identification of protein targets and the mechanism of the cytotoxic action of Ipomoea turpethum extract loaded nanoparticles against breast cancer cells. Journal of materials chemistry. B. vol 7. issue 39. 2020-08-20. PMID:31549130. |
root extract, was loaded on the nanoparticles and the cytotoxicity was evaluated in breast cancer cell lines (mcf-7 and mda-mb-231) by various cytotoxic assays like mtt assay, cfse cell proliferation assay, apoptosis assay, cell cycle study and dapi nuclear staining. |
2020-08-20 |
2023-08-13 |
Not clear |
| Hongping Cheng, Anshoo Malhotr. Evaluation of Potential of Long Noncoding RNA NEAT1 in Colorectal Cancer. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. vol 39. issue 2. 2020-08-20. PMID:32749120. |
cell proliferation and apoptosis were measured by 3-(4,5-dimethylthiazole-2-y1)-2,5-diphenyl tetrazolium bromide (mtt) assay and flow cytometry. |
2020-08-20 |
2023-08-13 |
Not clear |
| P Cheng, P Lu, J Guan, Y Zhou, L Zou, X Yi, H Chen. LncRNA KCNQ1OT1 controls cell proliferation, differentiation and apoptosis by sponging miR-326 to regulate c-Myc expression in acute myeloid leukemia. Neoplasma. vol 67. issue 2. 2020-08-17. PMID:31390869. |
cell proliferation, apoptosis and differentiation were measured by mtt assay, flow cytometry and qrt-pcr, respectively. |
2020-08-17 |
2023-08-13 |
Not clear |
| W L Lv, Y Y Hu, Z N Li, W Zhang, Q Pa. PAX3 silencing suppresses gastric cancer proliferation and angiogenesis via MET/PI3K signaling. Neoplasma. vol 67. issue 2. 2020-08-17. PMID:31847528. |
the proliferation, apoptosis and angiogenesis of gastric cancer cells were assessed using mtt assay, flow cytometry and in vitro tube formation assay. |
2020-08-17 |
2023-08-13 |
mouse |
| Xue Li, Caiwen Wei, Zhaozhi Zhang, Qu Jin, Xue Xia. MiR-134-5p Regulates Myocardial Apoptosis and Angiogenesis by Directly Targeting KDM2A After Myocardial Infarction. International heart journal. vol 61. issue 4. 2020-08-12. PMID:32684588. |
the influence of mir-134-5p on cardiomyocytes apoptosis was detected using methyl thiazolyl tetrazolium (mtt) assay. |
2020-08-12 |
2023-08-13 |
mouse |
| Jianteng Wei, Linghao Zhang, Jianfei Liu, Dong Pei, Ningli Wang, Han Wang, Duolong Di, Yewei Li. Protective effect of Lycium barbarum polysaccharide on ethanol-induced injury in human hepatocyte and its mechanism. Journal of food biochemistry. 2020-08-03. PMID:32744344. |
the cell survival rate, the apoptosis rate, and the intracellular ros level was detected by mtt assay, flow cytometry, laser confocal microscopy, and fluorescence spectrophotometry, respectively. |
2020-08-03 |
2023-08-13 |
human |
| Yu Pan, Andong Zhao, Zhiqiang Zhong, Xiaohua Pan, Sa Ca. Ganoderma spore lipid protects mouse bone marrow mesenchymal stem cells and hematopoiesis from the cytotoxicity of the chemotherapeutic agent. Biotechnology progress. vol 35. issue 5. 2020-07-29. PMID:31207156. |
mtt and annexin v/propidium iodide (pi) analyses found that gsl pre-treatment and co-treatment increased the proliferation and decreased the apoptosis in ctx-treated mscs. |
2020-07-29 |
2023-08-13 |
mouse |
| Qianyuan Li, Xiukou Zhou, Zhengyu Fang, Huamiao Zho. Knockdown of KLK12 inhibits viability and induces apoptosis in human colorectal cancer HT-29 cell line. International journal of molecular medicine. vol 44. issue 5. 2020-07-27. PMID:31485623. |
cell viability, migration, invasion and apoptosis were detected by mtt, wound healing, transwell and flow cytometry assays, respectively. |
2020-07-27 |
2023-08-13 |
human |
| Mengying Wang, Zhengzheng Li, Meng Zhang, Hui Wang, Ying Zhang, Yiping Feng, Yinan Liu, Jinghong Che. Decorin knockdown affects the gene expression profile of adhesion, growth and extracellular matrix metabolism in C-28/I2 chondrocytes. PloS one. vol 15. issue 4. 2020-07-27. PMID:32353084. |
mtt, adhesion assays and flow cytometry were used to investigate the effect of decorin knockdown on cell proliferation, adhesion, and apoptosis. |
2020-07-27 |
2023-08-13 |
human |
| Yan Wen, Guohui Liu, Yun Zhang, Hai L. MicroRNA-205 is associated with diabetes mellitus-induced erectile dysfunction via down-regulating the androgen receptor. Journal of cellular and molecular medicine. vol 23. issue 5. 2020-07-24. PMID:30729682. |
meanwhile, the effects of mir-205 and ar on cell proliferation and apoptosis were evaluated using mtt assay and flow cytometry respectively. |
2020-07-24 |
2023-08-13 |
rat |
| Zhengfei Shan, Yongwei Li, Shengqiang Yu, Jitao Wu, Chengjun Zhang, Yue Ma, Guimin Zhuang, Jiantao Wang, Zhenli Gao, Dongfu Li. CTCF regulates the FoxO signaling pathway to affect the progression of prostate cancer. Journal of cellular and molecular medicine. vol 23. issue 5. 2020-07-24. PMID:30873749. |
the rates of cell proliferation, cell invasion and apoptosis were examined by mtt assay, cell invasion assay and flow cytometry under different interference conditions. |
2020-07-24 |
2023-08-13 |
mouse |
| Z Ma, D F J Ketelhuth, T Wirström, T Ohki, M J Forteza, H Wang, V Grill, C B Wollheim, A Björklun. Increased uptake of oxLDL does not exert lipotoxic effects in insulin-secreting cells. Journal of molecular endocrinology. vol 62. issue 4. 2020-07-20. PMID:30917339. |
exposure to concentrations of oxldl from 20 to 100 µg/ml dose-dependently increased toxicity (evaluated by mtt) as well as apoptosis. |
2020-07-20 |
2023-08-13 |
mouse |