Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Jie Ren, Xiaodan Li, Hao Dong, Longlong Suo, Jun Zhang, Lina Zhang, Jing Zhan. miR-210-3p regulates the proliferation and apoptosis of non-small cell lung cancer cells by targeting SIN3A. Experimental and therapeutic medicine. vol 18. issue 4. 2020-10-01. PMID:31555365. |
furthermore, a549 and h1299 nsclc cells were cultured and transfected with mir-210-3p inhibitors, and mtt and propidium iodide/annexin v assays were performed to investigate the effects of mir-210-3p inhibition on the proliferation and apoptosis of the cells. |
2020-10-01 |
2023-08-13 |
human |
Zailong Zhou, Jian M. Gambogic acid suppresses colon cancer cell activity Experimental and therapeutic medicine. vol 18. issue 4. 2020-10-01. PMID:31555380. |
differences in cell proliferation, apoptosis and cell cycle, invasion, and migration were measured between groups using mtt, flow cytometry, transwell and wound-healing assays, respectively. |
2020-10-01 |
2023-08-13 |
human |
Xiao-Li Ma, Hua Yao, Xiao Wang, Yu Wei, Lei-Yu Cao, Qian Zhang, Li Zhan. ILK predicts the efficacy of chemoradiotherapy and the prognosis of patients with esophageal squamous cell carcinoma. Oncology letters. vol 18. issue 4. 2020-10-01. PMID:31579417. |
cell proliferation was detected using mtt, clonogenic and fluorescence assays, and apoptosis was assessed using flow cytometry. |
2020-10-01 |
2023-08-13 |
Not clear |
Fengrong Sun, Cuiping Zhang, Deliang Ma, Kai Wan. MicroRNA-544 inhibits esophageal squamous cell carcinoma cell proliferation and enhances sensitivity to cisplatin by repressing E2F transcription factor 5. Oncology letters. vol 18. issue 4. 2020-10-01. PMID:31579422. |
cell proliferation and cell apoptosis were assessed by mtt and flow cytometry assays. |
2020-10-01 |
2023-08-13 |
Not clear |
Zeinab Shirvani-Farsani, Mehrdad Behmanes. RNAi-mediated knockdown of VDR surprisingly suppresses cell growth in Jurkat T and U87-MG cells. Heliyon. vol 5. issue 11. 2020-10-01. PMID:31763486. |
next, growth, apoptosis, and cell cycle were evaluated using mtt assay and annexin vdr along with flowcytometry. |
2020-10-01 |
2023-08-13 |
Not clear |
Hui Tong, Tao Li, Weihua Qiu, Zhecheng Zh. Claudin-1 silencing increases sensitivity of liver cancer HepG2 cells to 5-fluorouracil by inhibiting autophagy. Oncology letters. vol 18. issue 6. 2020-10-01. PMID:31788043. |
mtt and annexin v-fluorescein isothiocyanate/propidium iodide assays demonstrated that cldn1 silencing significantly inhibits proliferation and enhances apoptosis induced by 5-fu treatment in hep/5fu cells, compared with non-silenced hep/5fu cells. |
2020-10-01 |
2023-08-13 |
Not clear |
Miaomiao Yu, Jinxia Li. MicroRNA-30d-5p promotes ovarian granulosa cell apoptosis by targeting Smad2. Experimental and therapeutic medicine. vol 19. issue 1. 2020-10-01. PMID:31853272. |
the levels of mir-30d-5p were detected via reverse transcription-quantitative pcr (rt-qpcr), cell proliferation was detected via an mtt assay and cell apoptosis was measured via flow cytometry. |
2020-10-01 |
2023-08-13 |
rat |
Ming Li, Yingxin Wang, Xia Liu, Zhenduo Zhang, Liwei Wang, Yong L. miR-629 targets FOXO3 to promote cell apoptosis in gastric cancer. Experimental and therapeutic medicine. vol 19. issue 1. 2020-10-01. PMID:31853302. |
additionally, the cell proliferation and apoptosis rate were determined via an mtt assay and flow cytometry, respectively. |
2020-10-01 |
2023-08-13 |
human |
Lili Ren, Wenju Mo, Linling Wang, Xiaojia Wan. Matrine suppresses breast cancer metastasis by targeting ITGB1 and inhibiting epithelial-to-mesenchymal transition. Experimental and therapeutic medicine. vol 19. issue 1. 2020-10-01. PMID:31853313. |
the proliferation of mda-mb-231 cells was inhibited and apoptosis was induced following treatment with mat, as determined by mtt and annexin-v-fitc/pi assays. |
2020-10-01 |
2023-08-13 |
human |
Han Peng, Hua Yang, Xin Xiang, Shenggang L. ΜicroRNA-221 participates in cerebral ischemic stroke by modulating endothelial cell function by regulating the PTEN/PI3K/AKT pathway. Experimental and therapeutic medicine. vol 19. issue 1. 2020-10-01. PMID:31885694. |
cell viability, migration and invasion, and cell apoptosis were determined using mtt assay, transwell assay and flow cytometry respectively. |
2020-10-01 |
2023-08-13 |
human |
Tingting Meng, Shiman Shen, Cheng Li, Xuehua Li. MicroRNA-1236-3p/translationally controlled tumor protein (TPT1) axis participates in congenital hypothyroidism progression by regulating neuronal apoptosis. Experimental and therapeutic medicine. vol 19. issue 1. 2020-10-01. PMID:31885695. |
flow cytometry and mtt assay were used to measure neuronal cell apoptosis and cell viability, whereas western blotting was applied to detect the expression of pim-3, p-bad (ser112), bad and bcl-xl, proteins associated with apoptosis. |
2020-10-01 |
2023-08-13 |
rat |
Xinchen Zhang, Liying Zhang, Shu Wang, Dequan Wu, Weiliang Yan. Decreased functional expression of Grp78 and Grp94 inhibits proliferation and attenuates apoptosis in a human gastric cancer cell line Oncology letters. vol 9. issue 3. 2020-09-30. PMID:25663878. |
the rates of cellular proliferation and apoptosis were assayed using mtt and flow cytometry analyses, respectively. |
2020-09-30 |
2023-08-13 |
human |
Jianjun Gu, Rong Xu, Yaxing Li, Jianhe Zhang, Shousen Wan. MicroRNA-218 modulates activities of glioma cells by targeting HMGB1. American journal of translational research. vol 8. issue 9. 2020-09-30. PMID:27725858. |
the cell proliferation, apoptosis, migration and invasion were studied using mtt, flow cytometry, transwell assay and scratch-wound assay, respectively. |
2020-09-30 |
2023-08-13 |
Not clear |
Qifeng Luo, Shiva Basnet, Zhenling Dai, Shuping Li, Zhenyu Zhang, Haiyan G. A novel E1B55kDa-deleted oncolytic adenovirus carrying microRNA-143 exerts specific antitumor efficacy on colorectal cancer cells. American journal of translational research. vol 8. issue 9. 2020-09-30. PMID:27725862. |
mtt and cell apoptosis assays were applied to explore the biological functions of ad-zd55-mir-143 within sw480 cells. |
2020-09-30 |
2023-08-13 |
human |
Yunfeng Yi, Xiujuan Lu, Jianming Chen, Changjie Jiao, Jing Zhong, Zhiming Song, Xiaoping Yu, Baoli Li. Downregulated miR-486-5p acts as a tumor suppressor in esophageal squamous cell carcinoma. Experimental and therapeutic medicine. vol 12. issue 5. 2020-09-30. PMID:27882172. |
the present study aimed to analyze the expression levels of mir-486-5p in escc tissues and paired normal adjacent tissues, and determine the effects of mir-486-5p on esophageal cancer cells using mtt, wound scratch and apoptosis assays. |
2020-09-30 |
2023-08-13 |
Not clear |
Wenxian Zheng, Shuyan Han, Shantong Jiang, Lina Pang, Xiaohong Li, Xijuan Liu, Minhua Cao, Pingping L. Multiple effects of Xihuang pill aqueous extract on the Hs578T triple-negative breast cancer cell line. Biomedical reports. vol 5. issue 5. 2020-09-30. PMID:27882217. |
first, an mtt assay was used to evaluate the anti-proliferative activity of aexhp on the hs578t cell line; furthermore, the cell cycle distribution, mitochondrial membrane potential and apoptotic rate were determined by flow cytometry, and western blot analysis was used to assess the expression of apoptosis and cell cycle regulatory proteins to investigate the mechanisms of action. |
2020-09-30 |
2023-08-13 |
Not clear |
Wei Zhan, Xin Liao, Lei Yu, Tian Tian, Xing Liu, Jing Liu, Li-Jun Cai, Xuan Xiao, Ru-Jia Xie, Qin Yan. Effects of blueberries on migration, invasion, proliferation, the cell cycle and apoptosis in hepatocellular carcinoma cells. Biomedical reports. vol 5. issue 5. 2020-09-30. PMID:27882220. |
the mtt assay was used for detecting cell proliferation, transwell assay was performed for migration and invasion evaluation, and cell cycle and apoptosis were assessed by flow cytometry. |
2020-09-30 |
2023-08-13 |
human |
Li Li, Tianyang Xue, Wei Xu, Bin Zho. Effect of matrine combined with cisplatin on the expression of XIAP in human rhabdomyosarcoma RD cells. Oncology letters. vol 12. issue 5. 2020-09-30. PMID:27895732. |
an mtt assay and flow cytometry were applied to detect the survival and apoptotic rates, respectively, while rt-pcr was applied to detect the expression levels of x-linked inhibitor of apoptosis protein (xiap) mrna in the rd cells of each group. |
2020-09-30 |
2023-08-13 |
human |
Bo Huang, Hongli Zhou, Siwang Wang, Xian Ping Lang, Xiaodong Wan. Effect of silencing SATB1 on proliferation, invasion and apoptosis of A549 human lung adenocarcinoma cells. Oncology letters. vol 12. issue 5. 2020-09-30. PMID:27895736. |
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt), transwell and scratch assays were used to study cell proliferation, invasion and migration activity, and the apoptosis rate was tested by flow cytometry. |
2020-09-30 |
2023-08-13 |
human |
Thomas Gehrke, Agmal Scherzad, Stephan Hackenberg, Philipp Schendzielorz, Rudolf Hagen, Norbert Kleinsasse. Differences in tumor stroma derived from irradiated versus non-irradiated fibroblasts in a co-culture model with head and neck squamous cell carcinoma. Oncology letters. vol 12. issue 5. 2020-09-30. PMID:27900035. |
subsequently, cells were analyzed for tumor viability, apoptosis, and secretion of interleukin (il)-6 and -8 by performing an mtt assay, annexin v-propidium iodide test and enzyme-linked immunosorbent assay, respectively. |
2020-09-30 |
2023-08-13 |
human |