| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jing Cao, Meng Wang, Tao Wan. CCAAT enhancer binding protein β has a crucial role in regulating breast cancer cell growth via activating the TGF-β-Smad3 signaling pathway. Experimental and therapeutic medicine. vol 14. issue 2. 2020-09-30. PMID:28810620. |
cell viability, cell cycle and apoptosis were observed by mtt assay and flow cytometry analysis. |
2020-09-30 |
2023-08-13 |
human |
| Yuanchuan Wang, Xiaohong Yin, Long Zhao, Shun Li, Jie Duan, Renzhao Kuang, Junwei Dua. MicroRNA-200b inhibits pituitary tumor cell proliferation and invasion by targeting PKCα. Experimental and therapeutic medicine. vol 14. issue 2. 2020-09-30. PMID:28810639. |
att-20 cells were transfected with mir-200b mimics, pkcα sirna and mir-200b mimics + pkcα, and the changes in cellular proliferation, invasion and apoptosis were observed via mtt, transwell assay and flow cytometric analysis. |
2020-09-30 |
2023-08-13 |
Not clear |
| Xun Wang, Shuang Zou, Yu-Long Lan, Jin-Shan Xing, Xiao-Qiang Lan, Bo Zhan. Solasonine inhibits glioma growth through anti-inflammatory pathways. American journal of translational research. vol 9. issue 9. 2020-09-30. PMID:28979674. |
cell proliferation of glioma cells was determined by mtt assay, and the biological functions of solasonine were investigated by migration, colony formation, apoptosis assays and cell cycle analysis in glioma cells. |
2020-09-30 |
2023-08-13 |
mouse |
| Ke Liu, Jingxia Du, Linhai Rua. MicroRNA-21 regulates the viability and apoptosis of diffuse large B-cell lymphoma cells by upregulating B cell lymphoma-2. Experimental and therapeutic medicine. vol 14. issue 5. 2020-09-30. PMID:29067124. |
mtt assays, flow cytometric analysis and caspase-3 activity assays were used to evaluate cell viability and apoptosis of dlbcl cells, respectively. |
2020-09-30 |
2023-08-13 |
Not clear |
| Tatsunori Oguchi, Ran Ono, Mayumi Tsuji, Hidenobu Shozawa, Masayuki Somei, Manami Inagaki, Yukiko Mori, Taro Yasumoto, Kenjiro Ono, Yuji Kiuch. Cilostazol Suppresses Aβ-induced Neurotoxicity in SH-SY5Y Cells through Inhibition of Oxidative Stress and MAPK Signaling Pathway. Frontiers in aging neuroscience. vol 9. 2020-09-30. PMID:29089887. |
to evaluate the effect of csz on oxidative stress, we examined levels of reactive oxygen species (ros), nicotinamide adenine dinucleotide phosphate oxidase (nox) activity, mrna expression of nox4, and cu/zn-superoxide dismutase (sod), as well as apoptosis biomarkers [mtt, (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide), caspase-3 and -9 activities and staining of annexin v]. |
2020-09-30 |
2023-08-13 |
human |
| Jun-Hai Tang, Guo-Hao Huang, Ke-Jie Mou, Eric Erquan Zhang, Ningning Li, Lei Du, Xiao-Peng Zhu, Ling Chen, Hui Yang, Ke-Bin Zhang, Sheng-Qing L. Pyrrolidine dithiocarbamate sensitizes U251 brain glioma cells to temozolomide via downregulation of Oncology letters. vol 14. issue 5. 2020-09-30. PMID:29098021. |
proliferation, apoptosis and cell cycle analysis of u251 cells following treatment with pdtc and tmz was determined by an mtt assay and flow cytometry, respectively. |
2020-09-30 |
2023-08-13 |
Not clear |
| Hua Yu, Weiling Xu, Fangchao Gong, Baorong Chi, Junyi Chen, Ling Zho. MicroRNA-155 regulates the proliferation, cell cycle, apoptosis and migration of colon cancer cells and targets CBL. Experimental and therapeutic medicine. vol 14. issue 5. 2020-09-30. PMID:29104623. |
in order to investigate the biological functions of mir-155, mtt, colony formation and wound healing assays, cell cycle analysis and detection of apoptosis were performed. |
2020-09-30 |
2023-08-13 |
Not clear |
| Lu Jin, Yifan Li, Zeng Zhang, Tao He, Jia Hu, Jiaju Liu, Mingwei Chen, Yaoting Gui, Shangqi Yang, Xiangming Mao, Yun Chen, Yongqing La. miR-514a-3p functions as a tumor suppressor in renal cell carcinoma. Oncology letters. vol 14. issue 5. 2020-09-30. PMID:29113192. |
the function of mir-514a-3p in the proliferation, mobility and apoptosis of rcc cells (786-o and achn) was assessed by mtt, cck-8, cell scratch, transwell, hoechst 33342 staining and flow cytometry assay. |
2020-09-30 |
2023-08-13 |
Not clear |
| Kongliang Ke, Tingting Lo. MicroRNA-10a suppresses breast cancer progression via PI3K/Akt/mTOR pathway. Oncology letters. vol 14. issue 5. 2020-09-30. PMID:29113237. |
the proliferation, migration and apoptosis of breast cancer cells were analyzed using mtt assays, transwell assays and flow cytometry, respectively, following transfection of mcf-7 and mda-mb-231 cells with an mir-10a mimic or anti-mir-10a. |
2020-09-30 |
2023-08-13 |
human |
| Ning Wang, Hongxia Chen, Yinping Teng, Xionghui Ding, Huan Wu, Xianqing Ji. Artesunate inhibits proliferation and invasion of mouse hemangioendothelioma cells Oncology letters. vol 14. issue 5. 2020-09-30. PMID:29113263. |
cell viability, apoptosis and invasion were determined by an mtt assay, flow cytometric analysis and transwell invasion assay, respectively. |
2020-09-30 |
2023-08-13 |
mouse |
| Cun-Dong Fan, Jing-Yi Sun, Xiao-Ting Fu, Ya-Jun Hou, Yuan Li, Ming-Feng Yang, Xiao-Yan Fu, Bao-Liang Su. Astaxanthin Attenuates Homocysteine-Induced Cardiotoxicity Frontiers in physiology. vol 8. 2020-09-30. PMID:29311972. |
the mtt, flow cytometry analysis (fcm), tunel-dapi and western blotting results all demonstrated that atx significantly alleviated hcy-induced cytotoxicity in h9c2 cells through inhibition of mitochondria-mediated apoptosis. |
2020-09-30 |
2023-08-13 |
human |
| Yanfang He, Jie Bai, Ping Liu, Jianxin Dong, Yajuan Tang, Jianli Zhou, Ping Han, Jun Xing, Yan Chen, Xiangyang Y. miR-494 protects pancreatic β-cell function by targeting PTEN in gestational diabetes mellitus. EXCLI journal. vol 16. 2020-09-30. PMID:29333131. |
moreover, the role of this mir-494 in regulating the proliferation and apoptosis of pancreatic β-cells were determined by mtt assay and flow cytometry, respectively in ins1 cells transfected with a mir-494 mimic or inhibitor. |
2020-09-30 |
2023-08-13 |
Not clear |
| Wanwan Zhu, Chunmei Lv, Jiao Wang, Qiang Gao, Hui Zhu, Haixia We. Patuletin induces apoptosis of human breast cancer SK-BR-3 cell line via inhibiting fatty acid synthase gene expression and activity. Oncology letters. vol 14. issue 6. 2020-09-30. PMID:29344187. |
mtt assays and flow cytometry were used to measure cell growth and cell apoptosis, respectively, following patuletin treatment. |
2020-09-30 |
2023-08-13 |
human |
| Zhiwei Shang, Haixia Feng, Lisha Cui, Weiping Wang, Hongwei F. Propofol promotes apoptosis and suppresses the HOTAIR-mediated mTOR/p70S6K signaling pathway in melanoma cells. Oncology letters. vol 15. issue 1. 2020-09-30. PMID:29375720. |
b16f10 cells were cultured with different concentrations (0-10 µm) of propofol for 24 or 48 h. proliferation and apoptosis of b16f10 cells were detected using mtt assay and flow cytometry. |
2020-09-30 |
2023-08-13 |
Not clear |
| Lingfeng Wan, Xin Yuan, Mantian Liu, Boyu Xu. miRNA-223-3p regulates NLRP3 to promote apoptosis and inhibit proliferation of hep3B cells. Experimental and therapeutic medicine. vol 15. issue 3. 2020-09-30. PMID:29467847. |
hep3b cells were then transfected with mir-223 mimics and the proliferation and apoptosis were determined by an mtt and a flow cytometric assay, respectively. |
2020-09-30 |
2023-08-13 |
Not clear |
| Xuefeng Zhang, Yun Chen, Liming Dong, Benkang Sh. Effect of selective inhibition of aquaporin 1 on chemotherapy sensitivity of J82 human bladder cancer cells. Oncology letters. vol 15. issue 3. 2020-09-30. PMID:29467903. |
reverse transcription-polymerase chain reaction was used to quantify the expression of aqp-1mrna in the cells; cell viability was analyzed with mtt assay and apoptosis was measured by flow cytometry. |
2020-09-30 |
2023-08-13 |
human |
| Yanxia Sun, Yingzhen Gu. Expression of Caspase-1 in breast cancer tissues and its effects on cell proliferation, apoptosis and invasion. Oncology letters. vol 15. issue 5. 2020-09-30. PMID:29725399. |
the mtt method detected the changes to cell proliferation, flow cytometry detected the rate of apoptosis, and a transwell assay was employed to assess invasion. |
2020-09-30 |
2023-08-13 |
human |
| Jing Chen, Jun Liang, Shihai Liu, Shanai Song, Wenxuan Guo, Fangzhen She. Differential regulation of AKT1 contributes to survival and proliferation in hepatocellular carcinoma cells by mediating Notch1 expression. Oncology letters. vol 15. issue 5. 2020-09-30. PMID:29725418. |
molecular mechanisms and the influences of different regulation the expression of akt1 on hcc cell growth, proliferation were determined by western blotting, mtt and colony formation assays, cell cycle and apoptosis were investigated by flow cytometry. |
2020-09-30 |
2023-08-13 |
Not clear |
| Sha Feng, Jue Liu, Biao Cheng, Aiping Deng, Hong Zhan. (-)-Epigallocatechin-3-gallate protects PC12 cells against corticosterone-induced neurotoxicity via the hedgehog signaling pathway. Experimental and therapeutic medicine. vol 15. issue 5. 2020-09-30. PMID:29731823. |
cell viability was assessed using an mtt assay, changes in cell morphology were observed using phase-contrast microscopy, cellular apoptosis was assessed by hoechst 33342 staining, cell proliferation was measured using a cell counting kit-8 assay, mrna levels were measured by reverse transcription-quantitative polymerase chain reaction and protein expression was assessed using western blot analysis. |
2020-09-30 |
2023-08-13 |
Not clear |
| Jing Xu, He Huang, Renjun Peng, Xiping Ding, Bing Jiang, Xianrui Yuan, Jian X. MicroRNA-30a increases the chemosensitivity of U251 glioblastoma cells to temozolomide by directly targeting beclin 1 and inhibiting autophagy. Experimental and therapeutic medicine. vol 15. issue 6. 2020-09-30. PMID:29805498. |
mtt and flow cytometry assay results showed that treatment with tmz inhibited the proliferation of u251 cells while inducing cell apoptosis in a dose-dependent manner. |
2020-09-30 |
2023-08-13 |
Not clear |