| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bo Huang, Hongli Zhou, Siwang Wang, Xian Ping Lang, Xiaodong Wan. Effect of silencing SATB1 on proliferation, invasion and apoptosis of A549 human lung adenocarcinoma cells. Oncology letters. vol 12. issue 5. 2020-09-30. PMID:27895736. |
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt), transwell and scratch assays were used to study cell proliferation, invasion and migration activity, and the apoptosis rate was tested by flow cytometry. |
2020-09-30 |
2023-08-13 |
human |
| Thomas Gehrke, Agmal Scherzad, Stephan Hackenberg, Philipp Schendzielorz, Rudolf Hagen, Norbert Kleinsasse. Differences in tumor stroma derived from irradiated versus non-irradiated fibroblasts in a co-culture model with head and neck squamous cell carcinoma. Oncology letters. vol 12. issue 5. 2020-09-30. PMID:27900035. |
subsequently, cells were analyzed for tumor viability, apoptosis, and secretion of interleukin (il)-6 and -8 by performing an mtt assay, annexin v-propidium iodide test and enzyme-linked immunosorbent assay, respectively. |
2020-09-30 |
2023-08-13 |
human |
| Jianjun Chen, Zhenjun Wang, Sanshui Y. AIM2 regulates viability and apoptosis in human colorectal cancer cells via the PI3K/Akt pathway. OncoTargets and therapy. vol 10. 2020-09-30. PMID:28243117. |
using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay and flow cytometry, we demonstrated that expression of aim2 inhibited the viability and increased the apoptosis rate of crc cells, and cell cycle analysis suggested that aim2 blocked cell cycle transition from g1 to s phase. |
2020-09-30 |
2023-08-13 |
human |
| Daiyong Wang, Bing Wang, Ruohan Wang, Zaizhong Zhang, Youdong Lin, Guoliang Huang, Songbin Lin, Yifan Jiang, Wenyuan Wang, Lie Wang, Qiaojia Huan. High expression of EGFR predicts poor survival in patients with resected T3 stage gastric adenocarcinoma and promotes cancer cell survival. Oncology letters. vol 13. issue 5. 2020-09-30. PMID:28521408. |
annexin v apoptosis and mtt cell viability assays were performed to explore the effect of egfr on ags gastric adenocarcinoma cell survival. |
2020-09-30 |
2023-08-13 |
Not clear |
| Xinmin Guo, Shunhua Guo, Liwen Pan, Li Ruan, Yingshi Gu, Jichuang La. Anti-microRNA-21/221 and microRNA-199a transfected by ultrasound microbubbles induces the apoptosis of human hepatoma HepG2 cells. Oncology letters. vol 13. issue 5. 2020-09-30. PMID:28529584. |
to determine the effect of anti-mir-21, anti-mir-221 and mir-199a on hepg2 cells, mtt, cell cycle analysis and annexin v-pe/7-add apoptosis assays were performed. |
2020-09-30 |
2023-08-13 |
human |
| Qifeng Luo, Heying Liu, Zhenyu Zhang, Shiva Basnet, Zhenling Dai, Shuping Li, Yuxiang Wang, Bin Xu, Haiyan G. A dual-regulated oncolytic adenovirus carrying TAp63 gene exerts potent antitumor effect on colorectal cancer cells. American journal of translational research. vol 9. issue 6. 2020-09-30. PMID:28670384. |
mtt and cell apoptosis assays were applied to explore the biological functions of ad-survivin-zd55-tap63 within hct116 cells. |
2020-09-30 |
2023-08-13 |
mouse |
| Xueming Ying, Jun Chen, Xueming Huang, Peng Huang, Shaocong Ya. Effect of AXL on the epithelial-to-mesenchymal transition in non-small cell lung cancer. Experimental and therapeutic medicine. vol 14. issue 1. 2020-09-30. PMID:28673000. |
furthermore, downregulation of axl expression by rna interference was shown to inhibit cell growth by inducing the apoptosis of pc9 cells, as demonstrated by mtt and flow cytometry analyses. |
2020-09-30 |
2023-08-13 |
Not clear |
| Zhi-Ren Zhang, Ming-Xia Gao, Kai Yan. Cucurbitacin B inhibits cell proliferation and induces apoptosis in human osteosarcoma cells via modulation of the JAK2/STAT3 and MAPK pathways. Experimental and therapeutic medicine. vol 14. issue 1. 2020-09-30. PMID:28673003. |
cucurbitacin b (20-100 µm) significantly reduced cell viability (p<0.05) and induced apoptosis, as assessed by mtt and annexin v/propidium iodide staining, along with inhibiting cell migration. |
2020-09-30 |
2023-08-13 |
human |
| Jing Cao, Meng Wang, Tao Wan. CCAAT enhancer binding protein β has a crucial role in regulating breast cancer cell growth via activating the TGF-β-Smad3 signaling pathway. Experimental and therapeutic medicine. vol 14. issue 2. 2020-09-30. PMID:28810620. |
cell viability, cell cycle and apoptosis were observed by mtt assay and flow cytometry analysis. |
2020-09-30 |
2023-08-13 |
human |
| Yuanchuan Wang, Xiaohong Yin, Long Zhao, Shun Li, Jie Duan, Renzhao Kuang, Junwei Dua. MicroRNA-200b inhibits pituitary tumor cell proliferation and invasion by targeting PKCα. Experimental and therapeutic medicine. vol 14. issue 2. 2020-09-30. PMID:28810639. |
att-20 cells were transfected with mir-200b mimics, pkcα sirna and mir-200b mimics + pkcα, and the changes in cellular proliferation, invasion and apoptosis were observed via mtt, transwell assay and flow cytometric analysis. |
2020-09-30 |
2023-08-13 |
Not clear |
| Xun Wang, Shuang Zou, Yu-Long Lan, Jin-Shan Xing, Xiao-Qiang Lan, Bo Zhan. Solasonine inhibits glioma growth through anti-inflammatory pathways. American journal of translational research. vol 9. issue 9. 2020-09-30. PMID:28979674. |
cell proliferation of glioma cells was determined by mtt assay, and the biological functions of solasonine were investigated by migration, colony formation, apoptosis assays and cell cycle analysis in glioma cells. |
2020-09-30 |
2023-08-13 |
mouse |
| Ke Liu, Jingxia Du, Linhai Rua. MicroRNA-21 regulates the viability and apoptosis of diffuse large B-cell lymphoma cells by upregulating B cell lymphoma-2. Experimental and therapeutic medicine. vol 14. issue 5. 2020-09-30. PMID:29067124. |
mtt assays, flow cytometric analysis and caspase-3 activity assays were used to evaluate cell viability and apoptosis of dlbcl cells, respectively. |
2020-09-30 |
2023-08-13 |
Not clear |
| Tatsunori Oguchi, Ran Ono, Mayumi Tsuji, Hidenobu Shozawa, Masayuki Somei, Manami Inagaki, Yukiko Mori, Taro Yasumoto, Kenjiro Ono, Yuji Kiuch. Cilostazol Suppresses Aβ-induced Neurotoxicity in SH-SY5Y Cells through Inhibition of Oxidative Stress and MAPK Signaling Pathway. Frontiers in aging neuroscience. vol 9. 2020-09-30. PMID:29089887. |
to evaluate the effect of csz on oxidative stress, we examined levels of reactive oxygen species (ros), nicotinamide adenine dinucleotide phosphate oxidase (nox) activity, mrna expression of nox4, and cu/zn-superoxide dismutase (sod), as well as apoptosis biomarkers [mtt, (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide), caspase-3 and -9 activities and staining of annexin v]. |
2020-09-30 |
2023-08-13 |
human |
| Jun-Hai Tang, Guo-Hao Huang, Ke-Jie Mou, Eric Erquan Zhang, Ningning Li, Lei Du, Xiao-Peng Zhu, Ling Chen, Hui Yang, Ke-Bin Zhang, Sheng-Qing L. Pyrrolidine dithiocarbamate sensitizes U251 brain glioma cells to temozolomide via downregulation of Oncology letters. vol 14. issue 5. 2020-09-30. PMID:29098021. |
proliferation, apoptosis and cell cycle analysis of u251 cells following treatment with pdtc and tmz was determined by an mtt assay and flow cytometry, respectively. |
2020-09-30 |
2023-08-13 |
Not clear |
| Hua Yu, Weiling Xu, Fangchao Gong, Baorong Chi, Junyi Chen, Ling Zho. MicroRNA-155 regulates the proliferation, cell cycle, apoptosis and migration of colon cancer cells and targets CBL. Experimental and therapeutic medicine. vol 14. issue 5. 2020-09-30. PMID:29104623. |
in order to investigate the biological functions of mir-155, mtt, colony formation and wound healing assays, cell cycle analysis and detection of apoptosis were performed. |
2020-09-30 |
2023-08-13 |
Not clear |
| Lu Jin, Yifan Li, Zeng Zhang, Tao He, Jia Hu, Jiaju Liu, Mingwei Chen, Yaoting Gui, Shangqi Yang, Xiangming Mao, Yun Chen, Yongqing La. miR-514a-3p functions as a tumor suppressor in renal cell carcinoma. Oncology letters. vol 14. issue 5. 2020-09-30. PMID:29113192. |
the function of mir-514a-3p in the proliferation, mobility and apoptosis of rcc cells (786-o and achn) was assessed by mtt, cck-8, cell scratch, transwell, hoechst 33342 staining and flow cytometry assay. |
2020-09-30 |
2023-08-13 |
Not clear |
| Kongliang Ke, Tingting Lo. MicroRNA-10a suppresses breast cancer progression via PI3K/Akt/mTOR pathway. Oncology letters. vol 14. issue 5. 2020-09-30. PMID:29113237. |
the proliferation, migration and apoptosis of breast cancer cells were analyzed using mtt assays, transwell assays and flow cytometry, respectively, following transfection of mcf-7 and mda-mb-231 cells with an mir-10a mimic or anti-mir-10a. |
2020-09-30 |
2023-08-13 |
human |
| Ning Wang, Hongxia Chen, Yinping Teng, Xionghui Ding, Huan Wu, Xianqing Ji. Artesunate inhibits proliferation and invasion of mouse hemangioendothelioma cells Oncology letters. vol 14. issue 5. 2020-09-30. PMID:29113263. |
cell viability, apoptosis and invasion were determined by an mtt assay, flow cytometric analysis and transwell invasion assay, respectively. |
2020-09-30 |
2023-08-13 |
mouse |
| Cun-Dong Fan, Jing-Yi Sun, Xiao-Ting Fu, Ya-Jun Hou, Yuan Li, Ming-Feng Yang, Xiao-Yan Fu, Bao-Liang Su. Astaxanthin Attenuates Homocysteine-Induced Cardiotoxicity Frontiers in physiology. vol 8. 2020-09-30. PMID:29311972. |
the mtt, flow cytometry analysis (fcm), tunel-dapi and western blotting results all demonstrated that atx significantly alleviated hcy-induced cytotoxicity in h9c2 cells through inhibition of mitochondria-mediated apoptosis. |
2020-09-30 |
2023-08-13 |
human |
| Yanfang He, Jie Bai, Ping Liu, Jianxin Dong, Yajuan Tang, Jianli Zhou, Ping Han, Jun Xing, Yan Chen, Xiangyang Y. miR-494 protects pancreatic β-cell function by targeting PTEN in gestational diabetes mellitus. EXCLI journal. vol 16. 2020-09-30. PMID:29333131. |
moreover, the role of this mir-494 in regulating the proliferation and apoptosis of pancreatic β-cells were determined by mtt assay and flow cytometry, respectively in ins1 cells transfected with a mir-494 mimic or inhibitor. |
2020-09-30 |
2023-08-13 |
Not clear |