| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhuo Chen, Liang Zhao, Feng Zhao, Guanghai Yang, Jian Jun Wan. Tetrandrine suppresses lung cancer growth and induces apoptosis, potentially via the VEGF/HIF-1α/ICAM-1 signaling pathway. Oncology letters. vol 15. issue 5. 2020-10-01. PMID:29849794. |
a549 human lung cancer cells were incubated with between 2.5 and 10 µm tetrandrine for 12, 24 and 48 h, following which the effect of tetrandrine on cell viability and apoptosis were assessed using an mtt assay and flow cytometry. |
2020-10-01 |
2023-08-13 |
human |
| Lili Li, Jiangtao Fan, Dahai Li, Yan Liu, Poonam Shrestha, Chunyan Zhong, Xiuhong Xia, Xiaobing Huan. Influence of YKL-40 gene RNA interference on the biological behaviors of endometrial cancer HEC-1A cells. Oncology letters. vol 16. issue 2. 2020-10-01. PMID:30008865. |
the biological behaviors, including cell proliferation, migration, invasion and apoptosis, were detected by mtt and transwell assays, and flow cytometry (fcm) analysis, respectively. |
2020-10-01 |
2023-08-13 |
human |
| Yali Gao, Zishen Zhao, Xiaoyin Meng, Hongguag Chen, Guojun F. Migration and invasion in B16-F10 mouse melanoma cells are regulated by Nrf2 inhibition during treatment with ionizing radiation. Oncology letters. vol 16. issue 2. 2020-10-01. PMID:30008889. |
small interfering (si)rnas targeting nrf2 were transfected into b16-f10 cells, and cell proliferation, invasion and apoptosis were detected by transwell, mtt or western blot assays. |
2020-10-01 |
2023-08-13 |
mouse |
| Ruihao Zhou, Juan Wu, Xiaofeng Tang, Xin Wei, Cheng Ju, Feifei Zhang, Jun Sun, Deyong Shuai, Zhiping Zhang, Qiong Liu, Xiao-Bin L. Histone deacetylase inhibitor AR-42 inhibits breast cancer cell growth and demonstrates a synergistic effect in combination with 5-FU. Oncology letters. vol 16. issue 2. 2020-10-01. PMID:30008890. |
mtt assays and colony formation assays were conducted to measure the proliferation of mcf-7 cells, and flow cytometry was used to analyze cell apoptosis. |
2020-10-01 |
2023-08-13 |
Not clear |
| Yameng Dong, Haozhan Yuan, Guangyu Ji. Identification of long non-coding RNA CCAT1 as an oncogene in nasopharyngeal carcinoma. Oncology letters. vol 16. issue 2. 2020-10-01. PMID:30013670. |
the function of ccat1 in the proliferation, migration, invasion and apoptosis of npc cells was detected by mtt, cell scratch, transwell, flow cytometry and caspase-3 elisa assays, respectively. |
2020-10-01 |
2023-08-13 |
human |
| Ting Wang, Qun Cai, Wen-Jie Yang, Hai-Hua Fan, Jian-Feng Yi, Feng X. MicroRNA-219 alleviates glutamate-induced neurotoxicity in cultured hippocampal neurons by targeting calmodulin-dependent protein kinase II gamma. Neural regeneration research. vol 13. issue 7. 2020-10-01. PMID:30028330. |
after neurons were transfected with mir-219 mimic, effects on cell viability and apoptosis were measured by 3-(4,5-dimethylthiazolyl-2)-2,5-diphenyltetrazolium bromide (mtt) assay and flow cytometry. |
2020-10-01 |
2023-08-13 |
rat |
| Ting Wang, Qun Cai, Wen-Jie Yang, Hai-Hua Fan, Jian-Feng Yi, Feng X. MicroRNA-219 alleviates glutamate-induced neurotoxicity in cultured hippocampal neurons by targeting calmodulin-dependent protein kinase II gamma. Neural regeneration research. vol 13. issue 7. 2020-10-01. PMID:30028330. |
mtt, flow cytometry, and caspase-3 activity assays showed that mir-219 overexpression could elevate glutamate-induced cell viability, and reduce cell apoptosis and caspase-3 activity. |
2020-10-01 |
2023-08-13 |
rat |
| Shuo Feng, Yingui Su. Protective role of propofol in endometriosis and its mechanism. Experimental and therapeutic medicine. vol 16. issue 4. 2020-10-01. PMID:30233720. |
crl-7566 cells were first treated with various concentrations of propofol (0, 1, 5 or 10 µg/ml) for specific duration, and the cell viability and apoptotic rate were determined by performing an mtt and a flow cytometric cell apoptosis assay, respectively. |
2020-10-01 |
2023-08-13 |
Not clear |
| Jun Chen, Jian He, Yue Yang, Jiannong Jian. An analysis of the expression and function of myeloid differentiation factor 88 in human osteosarcoma. Oncology letters. vol 16. issue 4. 2020-10-01. PMID:30250559. |
additionally, cell proliferation, invasion and apoptosis were examined using an mtt assay, transwell assay and annexin v-fluorescein isothiocyanate staining kit, respectively. |
2020-10-01 |
2023-08-13 |
human |
| Lei Li, Xiaoqing Zhou, Yanran Wan. Smokeless tobacco extract inhibits proliferation and promotes apoptosis in oral mucous fibroblasts. Oncology letters. vol 16. issue 4. 2020-10-01. PMID:30250574. |
the cell viability was measured with mtt assays, which detected the cell apoptosis rate via flow cytometry. |
2020-10-01 |
2023-08-13 |
human |
| Chengwei Zhou, Yonggang Zhu, Bin Lu, Weijun Zhao, Xiaodong Zha. Survivin expression modulates the sensitivity of A549 lung cancer cells resistance to vincristine. Oncology letters. vol 16. issue 4. 2020-10-01. PMID:30250619. |
mtt, annexin v-fluorescein isothiocyanate/propidium iodide and caspase-3 activity assays indicated that survivin silencing significantly inhibited cell viability and enhanced apoptosis induced by vincristine treatment in a549/vcr cells compared with non-silenced a549/vcr cells. |
2020-10-01 |
2023-08-13 |
Not clear |
| Raquel Martins Martinez, Deborah de Almeida Bauer Guimarães, Camila Ramos Berniz, Joel Pimentel de Abreu, Ana Paula Machado da Rocha, Roberto Soares de Moura, Angela Castro Resende, Anderson Junger Teodor. Açai ( Foods (Basel, Switzerland). vol 7. issue 11. 2020-10-01. PMID:30373103. |
human lung carcinoma cell viability (a549) was monitored by mtt assay method and the effects on cell cycle and apoptosis were measured by flow cytometry. |
2020-10-01 |
2023-08-13 |
human |
| Yubo Guo, Xiaohua Pe. Tetrandrine-Induced Autophagy in MDA-MB-231 Triple-Negative Breast Cancer Cell through the Inhibition of PI3K/AKT/mTOR Signaling. Evidence-based complementary and alternative medicine : eCAM. vol 2019. 2020-10-01. PMID:30713576. |
cell viability and apoptosis were evaluated by mtt and annexin-v/pi double staining. |
2020-10-01 |
2023-08-13 |
Not clear |
| Zhigang Wang, Limei Liu, Xiaofeng Guo, Chunmei Guo, Wenxia Wan. microRNA-1236-3p Regulates DDP Resistance in Lung Cancer Cells. Open medicine (Warsaw, Poland). vol 14. 2020-10-01. PMID:30805558. |
the mtt and flow cytometry assays demonstrated that up-regulation of mir-1236-3p could markedly inhibit a549/ddp cell proliferation but promote apoptosis, which could be significantly reversed by pcdna3.1-tpt1 plasmids. |
2020-10-01 |
2023-08-13 |
Not clear |
| Gökhan Kuş, Mete Özkurt, Pınar Öztopcu Vatan, Nilüfer Erkasap, Ruhi Uyar, Selda Kabader. Comparison of a ceramidase inhibitor (ceranib-2) with C2 ceramide and cisplatin on cytotoxicity and apoptosis of glioma cells. Turkish journal of biology = Turk biyoloji dergisi. vol 42. issue 3. 2020-10-01. PMID:30814888. |
we determined the in vitro survival rate with mtt assay, apoptosis with flow cytometry, gene expressions with qrt-pcr, and statistical significance by one-way analysis of variance together with tukey's test. |
2020-10-01 |
2023-08-13 |
human |
| Qiang Wang, Xiaolong Yu, Fan Li, Xin Lv, Xiaoxing Fu, Houyun Gu, Hucheng Liu, Jun Liu, Min Dai, Bin Zhan. Efficacy of celastrol combined with cisplatin in enhancing the apoptosis of U-2OS osteosarcoma cells via the mitochondrial and endoplasmic reticulum pathways of apoptosis. Oncology letters. vol 17. issue 3. 2020-10-01. PMID:30867764. |
mtt and annexin v-fitc/pi assays were used to evaluate the effects of combined celastrol/cisplatin on growth and apoptosis, respectively, in u-2os cells. |
2020-10-01 |
2023-08-13 |
human |
| Qiuyue Li, Yan Zeng, Qing Jiang, Cong Wu, Jing Zho. Role of mTOR signaling in the regulation of high glucose-induced podocyte injury. Experimental and therapeutic medicine. vol 17. issue 4. 2020-10-01. PMID:30906437. |
mtt assay and flow cytometry assay results indicated that hg significantly increased podocyte viability and apoptosis. |
2020-10-01 |
2023-08-13 |
Not clear |
| Fuquan Zhang, Donglai Chen, Wentao Yang, Shanzhou Duan, Yongbing Che. Combined effects of XAF1 and TRAIL on the apoptosis of lung adenocarcinoma cells. Experimental and therapeutic medicine. vol 17. issue 6. 2020-10-01. PMID:31086598. |
cell proliferationand cell apoptosis were detected by mtt assay and annexin v-fitc/pi double staining, respectively. |
2020-10-01 |
2023-08-13 |
mouse |
| Wipaporn Phatvej, Harish K Datta, Simon C Wilkinson, Elaine Mutch, Ann K Daly, Benjamin R Horrock. Endocytosis and Lack of Cytotoxicity of Alkyl-Capped Silicon Quantum Dots Prepared from Porous Silicon. Materials (Basel, Switzerland). vol 12. issue 10. 2020-10-01. PMID:31130663. |
previous work has shown that these particles are rapidly endocytosed by malignant cell lines and have little or no acute toxicity as judged by the standard 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay for viability and the terminal deoxynucleotidyl transferase dutp nick end labeling (tunel) assay for apoptosis. |
2020-10-01 |
2023-08-13 |
human |
| Xiangyan Cui, Ning Fang, Yu Cui, Dong Xiao, Xin Wan. Long non-coding RNA NEF inhibits proliferation and promotes apoptosis of laryngeal squamous cell carcinoma cells by inhibiting Wnt/β-catenin signaling. Oncology letters. vol 17. issue 6. 2020-10-01. PMID:31186702. |
the effects of nef overexpression on cell proliferation, apoptosis and β-catenin expression were explored by cell counting kit-8 cell proliferation assay, mtt assay and western blotting. |
2020-10-01 |
2023-08-13 |
human |