| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kaixiong Tao, Yuping Yin, Qian Shen, Ying Chen, Ruidong Li, Weilong Chang, Jie Bai, Weizhen Liu, Liang Shi, Peng Zhan. Akt inhibitor MK-2206 enhances the effect of cisplatin in gastric cancer cells. Biomedical reports. vol 4. issue 3. 2020-10-01. PMID:26998277. |
the mtt assay demonstrated that sequential treatment of cisplatin, followed by the akt inhibitor, mk-2206, caused a synergistic effect of proliferation inhibition, and the apoptosis assay by propidium iodide/fluorescein isothiocyanate staining also showed that combination treatment induced more apoptosis compared to the monotherapy groups. |
2020-10-01 |
2023-08-13 |
human |
| Baoqiang Wu, Yong Jiang, Feng Zhu, Donglin Sun, Hongjun Huan. Demethylation effects of elemene on the GSTP1 gene in HCC cell line QGY7703. Oncology letters. vol 11. issue 4. 2020-10-01. PMID:27073515. |
cell proliferation was measured with mtt assay, cell apoptosis and cell cycle were analyzed by flow cytometry, and gstp1 gene methylation was analyzed by methlation-specific polymerase chain reaction. |
2020-10-01 |
2023-08-13 |
Not clear |
| Jie Yao, Yu Wen Wang, Biao Biao Fang, Shu Jun Zhang, Bing Lin Chen. piR-651 and its function in 95-D lung cancer cells. Biomedical reports. vol 4. issue 5. 2020-10-01. PMID:27123245. |
the influence of pir-651 on tumor cell proliferation and apoptosis was detected by the mtt assay and flow cytometry. |
2020-10-01 |
2023-08-13 |
human |
| Shao-Jun Chen, Jian-Hai Lin, Xu-Dong Yao, Bo Peng, Yun-Fei Xu, Min Liu, Jun-Hua Zhen. Nrdp1-mediated degradation of BRUCE decreases cell viability and induces apoptosis in human 786-O renal cell carcinoma cells. Experimental and therapeutic medicine. vol 12. issue 2. 2020-10-01. PMID:27446249. |
in addition, mtt and apoptosis assays demonstrated that nrdp1 overexpression resulted in decreased cell viability and enhanced apoptosis in rcc 786-o cells; conversely, nrdp1 knockdown increased 786-o cell viability and inhibited apoptosis. |
2020-10-01 |
2023-08-13 |
human |
| Mi-Hua Liu, Jian Shan, Jian Li, Yuan Zhang, Xiao-Long Li. Resveratrol inhibits doxorubicin-induced cardiotoxicity via sirtuin 1 activation in H9c2 cardiomyocytes. Experimental and therapeutic medicine. vol 12. issue 2. 2020-10-01. PMID:27446329. |
apoptosis of h9c2 cardiomyocytes was assessed using the mtt assay and hoechst nuclear staining. |
2020-10-01 |
2023-08-13 |
Not clear |
| Jianhua Gao, Dan Liu, Jie Li, Qianlin Song, Qi Wan. Effect of STK17A on the sensitivity of ovarian cancer cells to paclitaxel and carboplatin. Oncology letters. vol 12. issue 2. 2020-10-01. PMID:27446402. |
the sensitivity of the transfected cells and controls to paclitaxel, carboplatin was examined by mtt assay, and the levels of proliferation and apoptosis were analyzed by flow cytometry. |
2020-10-01 |
2023-08-13 |
Not clear |
| Xiang-Kui Fan, Rui-Hua Yan, Xiang-Qun Geng, Jing-Shan Li, Xiang-Ming Chen, Jian-Zhe L. Biological significance of PinX1 telomerase inhibitor in esophageal carcinoma treatment. Experimental and therapeutic medicine. vol 12. issue 4. 2020-10-01. PMID:27698711. |
once successful transfection was achieved, the effects on the mrna level of human telomerase reverse transcriptase (htert), telomerase activity, cell proliferation and apoptosis were examined by semi-quantitative rt-pcr, stretch pcr, mtt assay and flow cytometry, respectively. |
2020-10-01 |
2023-08-13 |
human |
| Yiming Zhang, Zhao Liu, Min Zhou, Changjian Li. MicroRNA-129-5p inhibits vascular smooth muscle cell proliferation by targeting Wnt5a. Experimental and therapeutic medicine. vol 12. issue 4. 2020-10-01. PMID:27698769. |
the results of an mtt assay revealed that mir-129-5p inhibited the proliferation of smcs, and flow cytometry indicated that apoptosis was induced. |
2020-10-01 |
2023-08-13 |
mouse |
| Tomohiko Fukuda, Katsutoshi Oda, Osamu Wada-Hiraike, Kenbun Sone, Kanako Inaba, Yuji Ikeda, Chinami Makii, Aki Miyasaka, Tomoko Kashiyama, Michihiro Tanikawa, Takahide Arimoto, Tetsu Yano, Kei Kawana, Yutaka Osuga, Tomoyuki Fuji. Autophagy inhibition augments resveratrol-induced apoptosis in Ishikawa endometrial cancer cells. Oncology letters. vol 12. issue 4. 2020-10-01. PMID:27698828. |
cell proliferation, cell cycle progression and apoptosis were examined, following rsv exposure, by performing mtt assays, flow cytometry and annexin v staining, respectively, in an ishikawa endometrial cancer cell line. |
2020-10-01 |
2023-08-13 |
Not clear |
| Guoping Cao, Shenglan Gong, Fengxue Zhang, Wenjun F. Xiao Yao San against Corticosterone-Induced Stress Injury via Upregulating Glucocorticoid Receptor Reaction Element Transcriptional Activity. Evidence-based complementary and alternative medicine : eCAM. vol 2016. 2020-10-01. PMID:27822288. |
we found that xys and ru38486 could increase cell viabilities and decrease cell apoptosis by mtt, immunofluorescence, and flow cytometry assays. |
2020-10-01 |
2023-08-13 |
Not clear |
| Jie Lv, Wei Ou, Xiao-Hua Zou, Yin Yao, Jin-Li W. Effect of dexmedetomidine on hippocampal neuron development and BDNF-TrkB signal expression in neonatal rats. Neuropsychiatric disease and treatment. vol 12. 2020-10-01. PMID:28003751. |
cell activity and apoptosis were detected by the mtt and terminal deoxynucleotidyl transferase-mediated biotinylated uridine triphosphate (utp) nick end labeling assays. |
2020-10-01 |
2023-08-13 |
rat |
| Liang Yu, Zhendong Zhong, Hongbin Sun, Linxia Yan, Baomin He, Supin Li, Shuai Ma, Lili Yang, Yulan Huan. Effect of pterostilbene on glioma cells and related mechanisms. American journal of translational research. vol 8. issue 12. 2020-10-01. PMID:28077996. |
u87 glioma cell line was divided into control, normal culture and different dosages of pterostilbene groups, which received 5 mm or 10 mm pterostilbene for 48 h. mtt assay was used to detect u87 cell proliferation, while invasion assay was employed to test the effect of pterostilbene on cell invasion, followed by flow cytometry assay for analyzing u87 cell apoptosis. |
2020-10-01 |
2023-08-13 |
Not clear |
| Jie Liu, Hao Ren, Bin Liu, Qingyu Zhang, Mingyi Li, Runzhi Zh. Diosmetin inhibits cell proliferation and induces apoptosis by regulating autophagy via the mammalian target of rapamycin pathway in hepatocellular carcinoma HepG2 cells. Oncology letters. vol 12. issue 6. 2020-10-01. PMID:28101201. |
the effects of dios treatment on hepg2 cell proliferation and apoptosis rates were analyzed using mtt assays and annexin v staining, respectively. |
2020-10-01 |
2023-08-13 |
Not clear |
| Tao Jiang, Hongjun Zhang, Xiguang Liu, Hao Song, Ruyong Yao, Jianbin Li, Yuanyuan Zha. Effect of oxaliplatin combined with polyenephosphatidylcholine on the proliferation of human gastric cancer SGC-7901 cells. Oncology letters. vol 12. issue 6. 2020-10-01. PMID:28101212. |
the viability of sgc-7901 cells was verified by an mtt assay; flow cytometry was used to analyze the cell cycle and rates of cell apoptosis; oxidation-related indicators were measured by spectrophotometry, and the expression of cell cycle- and apoptosis-related proteins was determined by western blotting. |
2020-10-01 |
2023-08-13 |
human |
| Min Zhang, Li Jian. Oxidized low-density lipoprotein decreases VEGFR2 expression in HUVECs and impairs angiogenesis. Experimental and therapeutic medicine. vol 12. issue 6. 2020-10-01. PMID:28105106. |
ox-ldl decreased huvec proliferation by mtt, induced apoptosis by annexin v-fluorescein isothiocyanate (fitc) staining and markedly suppressed huvec tube formation by the matrigel assay in a dose-dependent manner. |
2020-10-01 |
2023-08-13 |
human |
| Jiaxin Li, Xuping Mao, Xing Wang, Ganggang Miao, Jiaxin L. miR-433 reduces cell viability and promotes cell apoptosis by regulating MACC1 in colorectal cancer. Oncology letters. vol 13. issue 1. 2020-10-01. PMID:28123526. |
furthermore, flow cytometry and mtt assays were used to examine the apoptosis, cell cycle distribution and viability of human colorectal cancer cells, and luciferase reporter and western blot assays were performed to verify the regulatory mechanism of mir-433 on macc1. |
2020-10-01 |
2023-08-13 |
human |
| Bo Chen, Yaoxi Tan, Yan Liang, Yan Li, Lei Chen, Shuangshuang Wu, Wei Xu, Yan Wang, Weihong Zhao, Jianqing W. Per2 participates in AKT-mediated drug resistance in A549/DDP lung adenocarcinoma cells. Oncology letters. vol 13. issue 1. 2020-10-01. PMID:28123577. |
per2 knockdown and overexpression in a549/ddp cells were used to compare cell proliferation (by mtt assay), apoptosis (active-caspase 3 western blot) and clone forming assay. |
2020-10-01 |
2023-08-13 |
Not clear |
| Jiao Liu, Chuang Chen, Guang Li, Dechang Chen, Qingshan Zho. Upregulation of TSPAN12 is associated with the colorectal cancer growth and metastasis. American journal of translational research. vol 9. issue 2. 2020-10-01. PMID:28337310. |
the vitro functional analysis, including mtt, colony formation, flow cytometry and transwell assays indicated that lentivirus-mediated tspan12 knockdown significantly suppressed cell proliferation, migration and invasion, induced cell apoptosis of crc cells. |
2020-10-01 |
2023-08-13 |
mouse |
| Fang Wu, Yizhi Liu, Jian Li, Lei Hou, Fuxi Lei, Shangke Huang, Lu Feng, Xinhan Zha. Human serum albumin-mediated apoptin delivery suppresses breast cancer cell growth Oncology letters. vol 13. issue 2. 2020-10-01. PMID:28356932. |
reverse transcription-quantitative polymerase chain reaction and western blotting were performed to detect the expression of apoptin in the transfected mcf-7 cells, while mtt assays and flow cytometry were conducted to detect cell viability and apoptosis. |
2020-10-01 |
2023-08-13 |
mouse |
| Yi-Xiang Fan, Zhi-Xin Liang, Qing-Zhu Liu, Han Xiao, Ke-Bin Li, Ji-Zhen W. Cell penetrating peptide of sodium-iodide symporter effect on the I-131 radiotherapy on thyroid cancer. Experimental and therapeutic medicine. vol 13. issue 3. 2020-10-01. PMID:28450931. |
mtt and flow cytometric analyses demonstrated that the cell growth and apoptosis rates of the tpc-1 cells were significantly inhibited and activated, respectively, by treatment with dtat np. |
2020-10-01 |
2023-08-13 |
Not clear |