| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hong Li, Bin Lian, Yaobang Liu, Dahai Chai, Jinping L. MicroRNA-1297 downregulation inhibits breast cancer cell epithelial-mesenchymal transition and proliferation in a FA2H-dependent manner. Oncology letters. vol 20. issue 6. 2020-10-06. PMID:33014155. |
mda-mb-231 cells were transfected with mir-1297 inhibitor or inhibitor control for 48 h. subsequently, mtt and flow cytometry assays indicated that mir-1297 inhibitor significantly decreased cell proliferation and induced apoptosis compared with the inhibitor control group. |
2020-10-06 |
2023-08-13 |
human |
| Mehdi Azizi, Hadi Valizadeh, Mehdi Shahgolzari, Mehdi Talebi, Elahe Baybordi, Mohammad Reza Dadpour, Roya Salehi, Mohammad Mehrmohammad. Synthesis of Self-Targeted Carbon Dot with Ultrahigh Quantum Yield for Detection and Therapy of Cancer. ACS omega. vol 5. issue 38. 2020-10-06. PMID:33015480. |
the highest cytotoxic and apoptotic effects were observed in mtx-cds compared to free mtx obtained by the mtt assay, cell cycle arrest, and annexin v-fitc apoptosis techniques. |
2020-10-06 |
2023-08-13 |
Not clear |
| Yueran Li, Songshu Xiao, Liu Dan, Min Xu. P16 Oncology letters. vol 9. issue 3. 2020-10-01. PMID:25663864. |
in addition, the proliferation and apoptosis rates of p16 knockdown siha-ddp cells were measured by mtt assay and annexin v flow cytometry and the subsequent changes in cyclin d1 and prb expression were analyzed by western blot analysis. |
2020-10-01 |
2023-08-13 |
human |
| Gang Han, Yan Wang, Wenzhi Bi, Jinpeng Jia, Wei Wan. MicroRNA-124 functions as a tumor suppressor and indicates prognosis in human osteosarcoma. Experimental and therapeutic medicine. vol 9. issue 3. 2020-10-01. PMID:25667613. |
mtt, flow cytometric, and transwell invasion and migration assays were used to test the proliferation, apoptosis, invasion and migration of osteosarcoma cells transfected with mir-124 mimic. |
2020-10-01 |
2023-08-13 |
human |
| Zhengming Su, Duqun Chen, Yifan Li, Enpu Zhang, Zuhu Yu, Ting Chen, Zhimao Jiang, Liangchao Ni, Shangqi Yang, Yaoting Gui, Jiongxian Ye, Yongqing La. microRNA-184 functions as tumor suppressor in renal cell carcinoma. Experimental and therapeutic medicine. vol 9. issue 3. 2020-10-01. PMID:25667660. |
the impacts of mir-184 on cell migration, proliferation and apoptosis were evaluated using migration scratch, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) and flow cytometry assay. |
2020-10-01 |
2023-08-13 |
human |
| Yiguo Wang, Changhong Liu, Sen Hong, Pengju Zhang, Qian Li. Effect of recombinant Hepatitis B virus on human glomerular mesangial cell apoptosis. Biotechnology, biotechnological equipment. vol 28. issue 4. 2020-10-01. PMID:26019555. |
cell proliferation was analysed by the methyl thiazole tetrazolium (mtt) assay and cell apoptosis, by flow cytometry. |
2020-10-01 |
2023-08-13 |
human |
| Yunhua Tang, Xiangyang Zhang, Fan Qi, Mingfeng Chen, Yuan Li, Longfei Liu, Wei He, Zhuo Li, Xiongbing Z. Afatinib inhibits proliferation and invasion and promotes apoptosis of the T24 bladder cancer cell line. Experimental and therapeutic medicine. vol 9. issue 5. 2020-10-01. PMID:26136904. |
mtt assay was used to estimate the proliferation of the t24 cells; flow cytometric analysis was used to estimate the effect of afatinib on t24 cell apoptosis; cell invasion ability was assessed by a transwell invasion assay; and western blot analysis was used to detect the expression of bcl-2, bax, akt, extracellular-signal-regulated kinase (erk)1/2, matrix metalloproteinase (mmp)-2 and mmp-9. |
2020-10-01 |
2023-08-13 |
human |
| Runqing Wang, Jie Zhao, Jiewen Zhang, Wei Liu, Meiying Zhao, Jiangtao Li, Juan Lv, Yanan L. Effect of lysosomal and ubiquitin-proteasome system dysfunction on the abnormal aggregation of α-synuclein in PC12 cells. Experimental and therapeutic medicine. vol 9. issue 6. 2020-10-01. PMID:26136940. |
the viability and metabolic state of the cells was assessed using the mtt assay; flow cytometry was used to measure the rate of cell apoptosis; and the double immunofluorescence method was applied to observe the formation of thioflavin s- and α-synuclein protein-positive aggregates and inclusion bodies in the pc12 cells. |
2020-10-01 |
2023-08-13 |
Not clear |
| Guangxin Zhang, Mei Sun, Yifan Zhang, Peiyan Hua, Xin Li, Ranji Cui, Xingyi Zhan. Dracorhodin perchlorate induces G Oncology letters. vol 10. issue 1. 2020-10-01. PMID:26171006. |
therefore, the present study aimed to investigate the effects of dp on cell viability, the cell cycle and apoptosis, using an mtt assay, flow cytometry and western blot studies. |
2020-10-01 |
2023-08-13 |
human |
| Lina Yang, Yuanyuan Liu, Chao Sun, Xinrui Yang, Zhen Yang, Juntao Ran, Qiuning Zhang, Hong Zhang, Xinyu Wang, Xiaohu Wan. Inhibition of DNA-PKcs enhances radiosensitivity and increases the levels of ATM and ATR in NSCLC cells exposed to carbon ion irradiation. Oncology letters. vol 10. issue 5. 2020-10-01. PMID:26722253. |
the cytotoxic activity, cell survival rate, dna damage repair ability, cell cycle arrest and apoptosis rate of the treated cells were analyzed with mtt assay, colony formation assay, immunofluorescence and flow cytometry, respectively. |
2020-10-01 |
2023-08-13 |
Not clear |
| Xueli Bai, Ling Ouyang, B O Li, Yang Zhou, Xin We. Expression of B cell-specific Moloney murine leukemia virus integration site 1 in vulvar squamous cell carcinoma and its effect on the biological behavior of A-431 cells. Oncology letters. vol 10. issue 6. 2020-10-01. PMID:26788137. |
the effects of bmi-1 silencing on cell proliferation, apoptosis and invasive ability were determined using an mtt assay, annexin v-fluorescein isothiocyanate/propidium iodide double-labeling experiment and transwell assay, respectively. |
2020-10-01 |
2023-08-13 |
human |
| Liangdong Jiang, Aiyong He, Xiaojie He, Cheng Ta. MicroRNA-126 enhances the sensitivity of osteosarcoma cells to cisplatin and methotrexate. Oncology letters. vol 10. issue 6. 2020-10-01. PMID:26788206. |
an mtt assay was conducted to detect transfected cell proliferation, and the effects of the chemotherapy drugs on transfected cell apoptosis were detected by flow cytometry. |
2020-10-01 |
2023-08-13 |
Not clear |
| Kaixiong Tao, Yuping Yin, Qian Shen, Ying Chen, Ruidong Li, Weilong Chang, Jie Bai, Weizhen Liu, Liang Shi, Peng Zhan. Akt inhibitor MK-2206 enhances the effect of cisplatin in gastric cancer cells. Biomedical reports. vol 4. issue 3. 2020-10-01. PMID:26998277. |
the mtt assay demonstrated that sequential treatment of cisplatin, followed by the akt inhibitor, mk-2206, caused a synergistic effect of proliferation inhibition, and the apoptosis assay by propidium iodide/fluorescein isothiocyanate staining also showed that combination treatment induced more apoptosis compared to the monotherapy groups. |
2020-10-01 |
2023-08-13 |
human |
| Baoqiang Wu, Yong Jiang, Feng Zhu, Donglin Sun, Hongjun Huan. Demethylation effects of elemene on the GSTP1 gene in HCC cell line QGY7703. Oncology letters. vol 11. issue 4. 2020-10-01. PMID:27073515. |
cell proliferation was measured with mtt assay, cell apoptosis and cell cycle were analyzed by flow cytometry, and gstp1 gene methylation was analyzed by methlation-specific polymerase chain reaction. |
2020-10-01 |
2023-08-13 |
Not clear |
| Jie Yao, Yu Wen Wang, Biao Biao Fang, Shu Jun Zhang, Bing Lin Chen. piR-651 and its function in 95-D lung cancer cells. Biomedical reports. vol 4. issue 5. 2020-10-01. PMID:27123245. |
the influence of pir-651 on tumor cell proliferation and apoptosis was detected by the mtt assay and flow cytometry. |
2020-10-01 |
2023-08-13 |
human |
| Shao-Jun Chen, Jian-Hai Lin, Xu-Dong Yao, Bo Peng, Yun-Fei Xu, Min Liu, Jun-Hua Zhen. Nrdp1-mediated degradation of BRUCE decreases cell viability and induces apoptosis in human 786-O renal cell carcinoma cells. Experimental and therapeutic medicine. vol 12. issue 2. 2020-10-01. PMID:27446249. |
in addition, mtt and apoptosis assays demonstrated that nrdp1 overexpression resulted in decreased cell viability and enhanced apoptosis in rcc 786-o cells; conversely, nrdp1 knockdown increased 786-o cell viability and inhibited apoptosis. |
2020-10-01 |
2023-08-13 |
human |
| Mi-Hua Liu, Jian Shan, Jian Li, Yuan Zhang, Xiao-Long Li. Resveratrol inhibits doxorubicin-induced cardiotoxicity via sirtuin 1 activation in H9c2 cardiomyocytes. Experimental and therapeutic medicine. vol 12. issue 2. 2020-10-01. PMID:27446329. |
apoptosis of h9c2 cardiomyocytes was assessed using the mtt assay and hoechst nuclear staining. |
2020-10-01 |
2023-08-13 |
Not clear |
| Jianhua Gao, Dan Liu, Jie Li, Qianlin Song, Qi Wan. Effect of STK17A on the sensitivity of ovarian cancer cells to paclitaxel and carboplatin. Oncology letters. vol 12. issue 2. 2020-10-01. PMID:27446402. |
the sensitivity of the transfected cells and controls to paclitaxel, carboplatin was examined by mtt assay, and the levels of proliferation and apoptosis were analyzed by flow cytometry. |
2020-10-01 |
2023-08-13 |
Not clear |
| Xiang-Kui Fan, Rui-Hua Yan, Xiang-Qun Geng, Jing-Shan Li, Xiang-Ming Chen, Jian-Zhe L. Biological significance of PinX1 telomerase inhibitor in esophageal carcinoma treatment. Experimental and therapeutic medicine. vol 12. issue 4. 2020-10-01. PMID:27698711. |
once successful transfection was achieved, the effects on the mrna level of human telomerase reverse transcriptase (htert), telomerase activity, cell proliferation and apoptosis were examined by semi-quantitative rt-pcr, stretch pcr, mtt assay and flow cytometry, respectively. |
2020-10-01 |
2023-08-13 |
human |
| Yiming Zhang, Zhao Liu, Min Zhou, Changjian Li. MicroRNA-129-5p inhibits vascular smooth muscle cell proliferation by targeting Wnt5a. Experimental and therapeutic medicine. vol 12. issue 4. 2020-10-01. PMID:27698769. |
the results of an mtt assay revealed that mir-129-5p inhibited the proliferation of smcs, and flow cytometry indicated that apoptosis was induced. |
2020-10-01 |
2023-08-13 |
mouse |