| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hailong Tang, Li Xu, Xi Cen, Li Yang, Juan Feng, Guang Li, Huafeng Zhu, Shan Gao, Yan Yu, Yaping Zhao, Zhiqiang Tian, Liping Hou, Shuchun Yu, Guangxun Ga. CDK5 inhibition in vitro and in vivo induces cell death in myeloma and overcomes the obstacle of bortezomib resistance. International journal of molecular medicine. vol 45. issue 6. 2021-01-21. PMID:32236619. |
the aim of this study is to investigate the effects of cdk5 on the viability of mm cells and bortezomib resistance using western blotting, immunohistochemistry, transient transfection, mtt assays, cell cycle analysis, apoptosis assays and a myeloma xenograft mouse model. |
2021-01-21 |
2023-08-13 |
mouse |
| Zheng Chen, Miaoxing Wu, Jiahua Li. Kelch-like protein 14 promotes proliferation and migration of ovarian cancer cells. International journal of clinical and experimental pathology. vol 13. issue 12. 2021-01-12. PMID:33425096. |
after constructing cell lines with a knocked down klhl14 gene, we used the mtt assay, flow cytometry with propidium iodide (pi), annexin v-fitc/pi, and transwell assay and found that knockdown of klhl14 gene inhibited proliferation of a-2780 cells, caused cell g0/g1 phase arrest, promoted apoptosis, and inhibited migration and invasiveness. |
2021-01-12 |
2023-08-13 |
Not clear |
| S A Pérez, M G Montalbán, G Carissimi, P Licence, G Víllor. In vitro cytotoxicity assessment of monocationic and dicationic pyridinium-based ionic liquids on HeLa, MCF-7, BGM and EA.hy926 cell lines. Journal of hazardous materials. vol 385. 2021-01-11. PMID:31727529. |
the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay, cell cycle arrest assays, apoptosis experiments and orange staining were carried out. |
2021-01-11 |
2023-08-13 |
Not clear |
| Fang Wang, Jiarui Li, Xinyue Tang, Kexin Huang, Lan Che. Polyelectrolyte three layer nanoparticles of chitosan/dextran sulfate/chitosan for dual drug delivery. Colloids and surfaces. B, Biointerfaces. vol 190. 2021-01-11. PMID:32155455. |
subsequently the cytotoxicity of nanoparticles was evaluated against hepg2 cells using mtt and apoptosis assay, resulting in synergistic effects between dual drugs and enhanced inhibition to cancer cells. |
2021-01-11 |
2023-08-13 |
Not clear |
| Caigu He, Xuehua Zheng, Xiuhong Lin, Xinying Chen, Chenyi She. Yunvjian-Medicated Serum Protects INS-1 Cells against Glucolipotoxicity-Induced Apoptosis through Autophagic Flux Modulation. Evidence-based complementary and alternative medicine : eCAM. vol 2020. 2021-01-11. PMID:33414841. |
mtt assay and flow cytometry were used to detect proliferation and apoptosis of ins-1 cells, respectively. |
2021-01-11 |
2023-08-13 |
Not clear |
| Ying-Juan Zheng, Tian-Song Liang, Juan Wang, Jing-Yi Zhao, Dao-Ke Yang, Zhang-Suo Li. Silencing lncRNA LOC101928963 Inhibits Proliferation and Promotes Apoptosis in Spinal Cord Glioma Cells by Binding to PMAIP1. Molecular therapy. Nucleic acids. vol 18. 2021-01-10. PMID:31670198. |
glioma cell proliferation and apoptosis were assessed by mtt assay and flow cytometry. |
2021-01-10 |
2023-08-13 |
Not clear |
| Zihao Chen, Hongping Ju, Ting Zhao, Shan Yu, Ping Li, Jing Jia, Nan Li, Xiaojie Jing, Bibo Tan, Yong L. hsa_circ_0092306 Targeting miR-197-3p Promotes Gastric Cancer Development by Regulating PRKCB in MKN-45 Cells. Molecular therapy. Nucleic acids. vol 18. 2021-01-10. PMID:31689616. |
annexin v-pi apoptosis flow cytometry, 3-(4,5dimethylthiazol- yl)-2,5dimethylthiazol-2-yl)-2,5diphenyltetrazolium bromide (mtt), wound healing, and transwell assays were applied to detect cell apoptosis, viability, migration, and invasion in mkn-45 cells, respectively. |
2021-01-10 |
2023-08-13 |
Not clear |
| Zhiqiang Li, Yaping Zhang, Nan Ding, Yudong Zhao, Zankai Ye, Lei Shen, Hanlu Yi, Yaobin Zh. Inhibition of lncRNA XIST Improves Myocardial I/R Injury by Targeting miR-133a through Inhibition of Autophagy and Regulation of SOCS2. Molecular therapy. Nucleic acids. vol 18. 2021-01-10. PMID:31734557. |
cell apoptosis was determined by flow cytometry analysis, and cell viability was used for 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-h-tetrazolium bromide, thiazolyl blue tetrazolium bromide (mtt) assay. |
2021-01-10 |
2023-08-13 |
mouse |
| Cheng Feng, Hai-Lin Zhang, Ang Zeng, Ming Bai, Xiao-Jun Wan. Tumor-Suppressive MicroRNA-216b Binds to TPX2, Activating the p53 Signaling in Human Cutaneous Squamous Cell Carcinoma. Molecular therapy. Nucleic acids. vol 20. 2021-01-10. PMID:32169806. |
a431 cells were transfected with mir-216b mimic, mir-216b inhibitor, or short interfering rna against tpx2 to evaluate cell proliferation, invasion, migration, and apoptosis using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay, scratch test, transwell assay, and flow cytometry. |
2021-01-10 |
2023-08-13 |
human |
| Wenyun Ting, Cheng Feng, Mingzi Zhang, Fei Long, Ming Ba. Overexpression of microRNA-203 Suppresses Proliferation, Invasion, and Migration while Accelerating Apoptosis of CSCC Cell Line SCL-1. Molecular therapy. Nucleic acids. vol 21. 2021-01-10. PMID:32668390. |
by conducting 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (mtt), scratch test, and transwell and flow cytometric analyses, mir-203 was witnessed to restrain scl-1 cell proliferation, migration, and invasion while accelerating their apoptosis. |
2021-01-10 |
2023-08-13 |
Not clear |
| Judong Luo, Hong Zhu, Hua Jiang, Yayun Cui, Mengjie Wang, Xinye Ni, Changsheng M. The effects of aberrant expression of LncRNA DGCR5/miR-873-5p/TUSC3 in lung cancer cell progression. Cancer medicine. 2021-01-09. PMID:29790668. |
for in vitro experiments, cell growth, migration, and invasion were significantly lower in a549 cells transfected with pcdna3.1-dgcr5 than pcdna3.1, which were verified by 5-diphenyltetrazolium bromide (mtt) assay, scratch test, and transwell assay, respectively, with no significant induction on cell apoptosis that was demonstrated by flow cytometry (fcm) assay. |
2021-01-09 |
2023-08-13 |
Not clear |
| Shulei Gong, Yu Li, Ling Lv, Wanfu Me. Restored microRNA-519a enhances the radiosensitivity of non-small cell lung cancer via suppressing EphA2. Gene therapy. 2021-01-08. PMID:33414521. |
mtt assay was used to measure cell proliferation, flow cytometry was performed for determination of cell cycle distribution and apoptosis. |
2021-01-08 |
2023-08-13 |
Not clear |
| Ailar Tupal, Mehdi Sabzichi, Roya Bazzaz, Nazila Fathi Maroufi, Maryam Mohammadi, Seyed Mohammadbagher Pirouzpanah, Fatemeh Ramezan. Application of ɑ-Tocotrienol-Loaded Biocompatible Precirol in Attenuation of Doxorubicin Dose-Dependent Behavior in HUH-7 Hepatocarcinoma Cell Line. Nutrition and cancer. vol 72. issue 4. 2021-01-07. PMID:31390910. |
to evaluate antiproliferative effects of formulation, apoptosis, cell cycle procedure, flow cytometry, and mtt assays were employed. |
2021-01-07 |
2023-08-13 |
Not clear |
| Shenyu Wang, Gongyin Zhao, Shujie Zhao, Yusen Qiao, Huilin Yan. The Effects of Interleukin-33 (IL-33) on Osteosarcoma Cell Viability, Apoptosis, and Epithelial-Mesenchymal Transition are Mediated Through the PI3K/AKT Pathway. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2021-01-05. PMID:32312946. |
the effects of il-33 on human osteosarcoma cell viability, apoptosis, emt, and the signaling pathways were studied using the mtt assay, flow cytometry, qrt-pcr, and western blot. |
2021-01-05 |
2023-08-13 |
human |
| Milagros R R Laborde, Marcelo L Larramendy, Sonia Solonesk. Cytotoxic and genotoxic assessments of 2,4-dichlorophenoxyacetic acid (2,4-D) in in vitro mammalian cells. Toxicology in vitro : an international journal published in association with BIBRA. vol 65. 2021-01-04. PMID:31987841. |
cytotoxicity was estimated by neutral red uptake (nru), succinic dehydrogenase activity (mtt) and apoptosis assessment. |
2021-01-04 |
2023-08-13 |
human |
| Li-Yun Fann, Jui-Hu Shih, Jen-Ho Tseng, Hsu-Shan Huang, Sheng-Huang Hsia. CC12 Induces Apoptotic Cell Death and Cell Cycle Arrest in Human Glioblastoma Cell Lines and Mouse Xenograft Model. Molecules (Basel, Switzerland). vol 25. issue 8. 2021-01-04. PMID:32295275. |
the observations of cell morphology, mtt assay, flow cytometry-based apoptosis after cc12 treatment, were conducted. |
2021-01-04 |
2023-08-13 |
mouse |
| Shouman Wang, Feiyu Chen, Lili Tan. IL-32 promotes breast cancer cell growth and invasiveness. Oncology letters. vol 9. issue 1. 2021-01-02. PMID:25435980. |
the effects of il-32 on cell proliferation and apoptosis were investigated by mtt assay and tunel staining, respectively. |
2021-01-02 |
2023-08-13 |
mouse |
| Nazila Fathi Maroufi, Vahid Vahedian, Seyed Ali Miresmaeili Mazrakhondi, Wesam Kooti, Hosein Ajami Khiavy, Roya Bazzaz, Fatemeh Ramezani, Seyed Mohammadbagher Pirouzpanah, Marjan Ghorbani, Maryam Akbarzadeh, Hamed Hajipour, Saeed Ghanbarzadeh, Mehdi Sabzich. Sensitization of MDA-MBA231 breast cancer cell to docetaxel by myricetin loaded into biocompatible lipid nanoparticles via sub-G1 cell cycle arrest mechanism. Naunyn-Schmiedeberg's archives of pharmacology. vol 393. issue 1. 2020-12-31. PMID:31372697. |
mtt, dapi staining, flow cytometric, and rt-pcr (real-time) assays were used to recognize novel formulation behavior on cell cytotoxicity as well as recognizing molecular mechanism of formulation concerning apoptosis phenomenon. |
2020-12-31 |
2023-08-13 |
Not clear |
| Jie Jiang, Peng Han, Jian Qian, Shaobo Zhang, Shangqian Wang, Qiang Cao, Pengfei Sha. Knockdown of ALPK2 blocks development and progression of renal cell carcinoma. Experimental cell research. vol 392. issue 2. 2020-12-31. PMID:32330508. |
the effects of alpk2 knockdown on cell proliferation, colony formation, cell migration and apoptosis were assessed by mtt, colony formation assay, wound-healing assay, transwell assay and flow cytometry, respectively. |
2020-12-31 |
2023-08-13 |
mouse |
| Qiong Yang, Wengdong Ma, Kun Yu, Qi Zhang, Zaiyuan Ye, Wenjie Xia, Shuguang L. Oridonin Suppresses Human Gastric Cancer Growth in Vitro and in Vivo via Inhibition of VEGF, Integrin β3, and PCNA. Biological & pharmaceutical bulletin. vol 43. issue 7. 2020-12-31. PMID:32612067. |
an in vitro 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay with bgc823 cells was used to examine the cytotoxicity and apoptosis associated with oridonin treatment. |
2020-12-31 |
2023-08-13 |
mouse |