| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jianfeng Zhang, Kai Zhang, Yingkui Ho. Long non‑coding RNA NNT‑AS1 knockdown represses the progression of gastric cancer via modulating the miR‑142‑5p/SOX4/Wnt/β‑catenin signaling pathway. Molecular medicine reports. vol 22. issue 2. 2021-03-16. PMID:32468065. |
the proliferation, apoptosis, migration and invasion of gc cells were determined using mtt, flow cytometry and transwell assays. |
2021-03-16 |
2023-08-13 |
Not clear |
| Dandan Zhao, Hongxia Zhao, Yang He, Yang Yang, Yan Du, Meixia Zhan. The inhibitive effects of proteasome inhibitor MG-132 on pterygium fibroblasts in vitro and the potential key regulators involved. Life sciences. vol 270. 2021-03-11. PMID:33482188. |
cell proliferation was examined by mtt, cell cycle and apoptosis were detected by flow cytometry. |
2021-03-11 |
2023-08-13 |
human |
| Ying Zhang, Xiangyang Cao, Peifeng Li, Yanan Fan, Leilei Zhang, Wuyin Li, Youwen Li. PSMC6 promotes osteoblast apoptosis through inhibiting PI3K/AKT signaling pathway activation in ovariectomy-induced osteoporosis mouse model. Journal of cellular physiology. vol 235. issue 7-8. 2021-03-10. PMID:32017075. |
further, mtt, bromodeoxyuridine, and flow cytometry assays revealed that psmc6 inhibition promoted the progression of cell cycle and cell proliferation, whereas, psmc6 overexpression promoted the apoptosis and inhibited cell cycle progression and cell proliferation in vitro. |
2021-03-10 |
2023-08-13 |
mouse |
| Shokoofe Noori, Mostafa Rezaei Tavirani, Niloofar Deravi, Mohammad Ismaiil Mahboobi Rabbani, Afshin Zargh. Naringenin Enhances the Anti-Cancer Effect of Cyclophosphamide against MDA-MB-231 Breast Cancer Cells Via Targeting the STAT3 Signaling Pathway. Iranian journal of pharmaceutical research : IJPR. vol 19. issue 3. 2021-03-10. PMID:33680016. |
apoptosis was measured via flowcytometric analysis of annexin v binding and cell viability was assessed via mtt assay. |
2021-03-10 |
2023-08-13 |
Not clear |
| Yu Jian, Qi Fa. Long non-coding RNA SNHG7 facilitates pancreatic cancer progression by regulating the miR-146b-5p/Robo1 axis. Experimental and therapeutic medicine. vol 21. issue 4. 2021-03-10. PMID:33680120. |
moreover, cell viability and apoptosis were assessed by mtt and flow cytometry assays, respectively. |
2021-03-10 |
2023-08-13 |
mouse |
| Xiao Liu, Zheng Li, Ming Li, Jingxiu Chai, Shan He, Jinfeng Wu, Jinhua X. Icariside II overcomes BRAF inhibitor resistance in melanoma by inducing ROS production and inhibiting MITF. Oncology reports. vol 44. issue 1. 2021-03-08. PMID:32319656. |
in the present study, we determined by mtt, flow cytometry and western blotting, respectively that is potentiated the plx4032‑induced downregulation of cell viability and increase in apoptosis and autophagy in braf inhibitor‑resistant melanoma. |
2021-03-08 |
2023-08-13 |
Not clear |
| Yi-Feng Yuan, Wen-Xiong Zhu, Tao Liu, Ju-Qiao He, Qing Zhou, Xing Zhou, Xi Zhang, Jing Yan. Cyclopamine functions as a suppressor of benign prostatic hyperplasia by inhibiting epithelial and stromal cell proliferation via suppression of the Hedgehog signaling pathway. International journal of molecular medicine. vol 46. issue 1. 2021-03-05. PMID:32319534. |
cell proliferation, cell cycle and apoptosis were analyzed using an mtt assay and flow cytometry. |
2021-03-05 |
2023-08-13 |
rat |
| Chuhai Xie, Binwei Chen, Boyi Wu, Jianhong Guo, Yulong Shi, Yanming Ca. CircSAMD4A regulates cell progression and epithelial‑mesenchymal transition by sponging miR‑342‑3p via the regulation of FZD7 expression in osteosarcoma. International journal of molecular medicine. vol 46. issue 1. 2021-03-05. PMID:32319545. |
mtt assay and flow cytometry were used to detect cell cytotoxicity and apoptosis, respectively. |
2021-03-05 |
2023-08-13 |
mouse |
| H N Gao, F Z Ren, P C Wen, L X Xie, R Wang, Z N Yang, Y X L. Yak milk-derived exosomal microRNAs regulate intestinal epithelial cells on proliferation in hypoxic environment. Journal of dairy science. vol 104. issue 2. 2021-03-05. PMID:33246613. |
in vitro assay of the role of bta-mir-34a on survival of iec-6 in hypoxia by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (mtt) confirmed its effectiveness to significantly increase iec-6 survival up to 13% for 12 h, and up to 9.5% for 24 h. investigation on the regulatory relationship between bta-mirna-34a and the hypoxia-inducible factor/apoptosis signaling pathway provided insights into the possible mechanisms by which bta-mir-34a activated the hypoxia-inducible factor and apoptosis signaling pathway, thus promoting iec-6 survival. |
2021-03-05 |
2023-08-13 |
Not clear |
| C J Wei, F Hua, Y H Chen, Z W Zhang, Z Y She. Muscone alleviates myocardial ischemia-reperfusion injury via inhibition of oxidative stress and enhancement of SIRT3. Journal of biological regulators and homeostatic agents. vol 35. issue 1. 2021-03-05. PMID:33480219. |
mtt assay and tunel assay were performed to investigate h9c2 viability and apoptosis, respectively. |
2021-03-05 |
2023-08-13 |
rat |
| Long Jin, Yu-Liang Pan, Jun Zhang, Pei-Guo Ca. LncRNA HOTAIR recruits SNAIL to inhibit the transcription of HNF4α and promote the viability, migration, invasion and EMT of colorectal cancer. Translational oncology. vol 14. issue 4. 2021-03-05. PMID:33588137. |
the cell viability, migration, invasion and apoptosis rate were evaluated using mtt, brdu,transwell and flow cytometryexperiments. |
2021-03-05 |
2023-08-13 |
mouse |
| Thoria Diab, Samar Sami AlKafaas, Thanaa Ibrahim Shalaby, Mohamed Hessie. Dexamethasone simulates the anticancer effect of nano-formulated paclitaxel in breast cancer cells. Bioorganic chemistry. vol 99. 2021-03-01. PMID:32240873. |
cells viability (assessed by mtt assay), apoptosis (assessed by flow cytometry) and the expression of ptx resistance gene (trx1) and ptx metabolizing genes (cyp2c8 and cyp3a4) were investigated. |
2021-03-01 |
2023-08-13 |
Not clear |
| Lihua Cui, Caixia Li, Yuzhen Zhuo, Lei Yang, Naiqiang Cui, Yuhong Li, Shukun Zhan. Saikosaponin A inhibits the activation of pancreatic stellate cells by suppressing autophagy and the NLRP3 inflammasome via the AMPK/mTOR pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 128. 2021-03-01. PMID:32497863. |
cell viability, proliferation, migration and apoptosis were evaluated by mtt assays, the icelligence system, transwell assays and flow cytometry. |
2021-03-01 |
2023-08-13 |
rat |
| Attila Biró, Arnold Markovics, Mónika Éva Fazekas, Gábor Fidler, Gábor Szalóki, Melinda Paholcsek, János Lukács, László Stündl, Judit Remenyi. Allithiamine Alleviates Hyperglycaemia-Induced Endothelial Dysfunction. Nutrients. vol 12. issue 6. 2021-03-01. PMID:32517031. |
the non-cytotoxic concentration of allithiamine was determined based on mtt, apoptosis, and necrosis assays. |
2021-03-01 |
2023-08-13 |
human |
| Huanhuan Xu, Litian Wang, Boya Shi, Lihong Hu, Chunxia Gan, Ya Wang, Zemin Xiang, Xuanjun Wang, Jun Shen. Caffeine inhibits the anticancer activity of paclitaxel via down-regulation of α-tubulin acetylation. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 129. 2021-03-01. PMID:32580047. |
in vitro studies, involving mtt assay, wound-healing assay, cell apoptosis assay, and western blotting analysis of a549 and hela cells, were performed. |
2021-03-01 |
2023-08-13 |
Not clear |
| Ainaz Mihanfar, Saber Ghazizadeh Darband, Shirin Sadighparvar, Mojtaba Kaviani, Mohammad Mirza-Aghazadeh-Attari, Bahman Yousefi, Maryam Majidini. In vitro and in vivo anticancer effects of syringic acid on colorectal cancer: Possible mechanistic view. Chemico-biological interactions. vol 337. 2021-03-01. PMID:33548266. |
in vitro effects of syringic acid treatment on human colorectal cancer sw-480 cell lines were assessed by performing cell proliferation assay (mtt and trypan blue staining), apoptosis assays (tunel assay, annexin-v/pi flowcytometry and lactate dehydrogenase release assay), measuring reactive oxygen species (ros), antioxidant enzymes and dna damage, and evaluating protein levels of proliferative genes, and autophagy markers. |
2021-03-01 |
2023-08-13 |
human |
| Baiqi Wang, Lili Xu, Ju Zhang, Xinru Cheng, Qianya Xu, Jian Wang, Fengxia Ma. LncRNA NORAD accelerates the progression and doxorubicin resistance of neuroblastoma through up-regulating HDAC8 via sponging miR-144-3p. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 129. 2021-02-26. PMID:32563146. |
the proliferation, chemoresistance, apoptosis, metastasis and autophagy of nb cells were determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt), flow cytometry, transwell migration and invasion assays and western blot assay, respectively. |
2021-02-26 |
2023-08-13 |
Not clear |
| Anquan Shang, Weiwei Wang, Chenzheng Gu, Wei Chen, Wenying Lu, Zujun Sun, Dong L. Long non-coding RNA CCAT1 promotes colorectal cancer progression by regulating miR-181a-5p expression. Aging. vol 12. issue 9. 2021-02-25. PMID:32380476. |
cell viability, colony formation ability, aggression and apoptosis were determined by mtt assay, colony formation assay, transwell and wound healing assays and flow cytometry analysis. |
2021-02-25 |
2023-08-13 |
Not clear |
| Mehrnaz Mehrabani, Mohammad Hadi Nematollahi, Mojde Esmaeili Tarzi, Kobra Bahrampour Juybari, Moslem Abolhassani, Ali Mohammad Sharifi, Hamze Paseban, Mohsen Saravani, Solmaz Mirzamohammad. Protective effect of hydralazine on a cellular model of Parkinson's disease: a possible role of hypoxia-inducible factor (HIF)-1α. Biochemistry and cell biology = Biochimie et biologie cellulaire. vol 98. issue 3. 2021-02-24. PMID:31940231. |
the cytotoxicity of hydralazine and 6-ohda on the sh-sy5y cells were evaluated by mtt [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] and apoptosis detection assays. |
2021-02-24 |
2023-08-13 |
Not clear |
| Qigang Xu, Wei Lin, Chonglin Tao, Xiaming Huang, Junjian L. Chondroitin polymerizing factor (CHPF) contributes to malignant proliferation and migration of hepatocellular carcinoma cells. Biochemistry and cell biology = Biochimie et biologie cellulaire. vol 98. issue 3. 2021-02-24. PMID:32383983. |
mtt assays, colony formation assays, and flow cytometry were used to evaluate the cell proliferation, colony formation, and cell apoptosis, respectively. |
2021-02-24 |
2023-08-13 |
human |