| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yu Zhao, Ding Ma, Bingchen Dong, Ming L. Per2 attenuates LPS-induced chondrocyte injury through the PTEN/PI3K/Akt signalling pathway. Bioscience reports. vol 40. issue 5. 2021-03-23. PMID:32426819. |
mtt assay, apoptosis analysis and enzyme-linked immunosorbent assay (elisa) results showed that per2 increased cell proliferation, while inhibited apoptosis and inflammation. |
2021-03-23 |
2023-08-13 |
Not clear |
| Ying Hu, Rong Xu, Yue He, Zhibo Zhao, Xudong Mao, Ling Lin, Jun H. Downregulation of microRNA‑106a‑5p alleviates ox‑LDL‑mediated endothelial cell injury by targeting STAT3. Molecular medicine reports. vol 22. issue 2. 2021-03-23. PMID:32626987. |
cell viability and apoptosis were assessed by mtt assay and flow cytometry, respectively. |
2021-03-23 |
2023-08-13 |
human |
| Wen-Jun Gan, Chen-Lin Gao, Wen-Qian Zhang, Jun-Ling Gu, Ting-Ting Zhao, Heng-Li Guo, Hua Zhou, Yong Xu, Li-Li Yu, Li-Fang Li, Ding-Kun Gui, You-Hua X. Kuwanon G protects HT22 cells from advanced glycation end product-induced damage. Experimental and therapeutic medicine. vol 21. issue 5. 2021-03-23. PMID:33747164. |
kwg was shown to significantly inhibit age-induced cell apoptosis in comparison with a control treatment, as determined by both mtt and flow cytometry. |
2021-03-23 |
2023-08-13 |
mouse |
| Xinghai Chen, Debiao Son. LPS promotes the progression of sepsis by activation of lncRNA HULC/miR-204-5p/TRPM7 network in HUVECs. Bioscience reports. vol 40. issue 6. 2021-03-22. PMID:32484206. |
cell viability and apoptosis were measured by methyl thiazolyl tetrazolium (mtt) and flow cytometry assays, respectively. |
2021-03-22 |
2023-08-13 |
human |
| Enikő Major, Anett Benedek, Marcell A Szász, Zoltán Benyó, Andrea Balog. [The adjuvant killing effect of modulated electro-hyperthermia combined with chemotherapy on B16F10 melanoma cells]. Magyar onkologia. vol 65. issue 1. 2021-03-19. PMID:33730119. |
cell viability was measured using mtt assay and apoptosis by annexin v/7-aad staining using flow cytometry 24 hours post-treatment. |
2021-03-19 |
2023-08-13 |
Not clear |
| Vivek K Chaturvedi, Navneet Yadav, Neeraj K Rai, Raghvendra A Bohara, Sachchida Nand Rai, Lotfi Aleya, Mohan P Sing. Two birds with one stone: oyster mushroom mediated bimetallic Au-Pt nanoparticles for agro-waste management and anticancer activity. Environmental science and pollution research international. vol 28. issue 11. 2021-03-18. PMID:33196993. |
furthermore, we examined the cytotoxic activity of au-pt nps using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (mtt) assay, intracellular reactive oxygen species (ros) generation, and apoptosis by propidium iodide assay. |
2021-03-18 |
2023-08-13 |
human |
| Bin-Hua Xue, Yi Liu, Hu Chen, Yun Sun, Wei-Li Y. A novel function of IRF9 in acute pancreatitis by modulating cell apoptosis, proliferation, migration, and suppressing SIRT1-p53. Molecular and cellular biochemistry. vol 472. issue 1-2. 2021-03-17. PMID:32577948. |
the apoptosis, proliferation, and migration of ar42j cells were checked by flow cytometry, mtt, and transwell assay. |
2021-03-17 |
2023-08-13 |
Not clear |
| Qiong Wang, Wenwen Zhu, Geqiong Xiao, Mengyu Ding, Jian Chang, Hui Lia. Effect of AGER on the biological behavior of non‑small cell lung cancer H1299 cells. Molecular medicine reports. vol 22. issue 2. 2021-03-16. PMID:32468030. |
ager expression and biological properties, including cell viability, apoptosis, migration and invasion abilities, in h1299 cells were investigated using mtt, flow cytometry, wound healing and transwell assays. |
2021-03-16 |
2023-08-13 |
human |
| Jianfeng Zhang, Kai Zhang, Yingkui Ho. Long non‑coding RNA NNT‑AS1 knockdown represses the progression of gastric cancer via modulating the miR‑142‑5p/SOX4/Wnt/β‑catenin signaling pathway. Molecular medicine reports. vol 22. issue 2. 2021-03-16. PMID:32468065. |
the proliferation, apoptosis, migration and invasion of gc cells were determined using mtt, flow cytometry and transwell assays. |
2021-03-16 |
2023-08-13 |
Not clear |
| Dandan Zhao, Hongxia Zhao, Yang He, Yang Yang, Yan Du, Meixia Zhan. The inhibitive effects of proteasome inhibitor MG-132 on pterygium fibroblasts in vitro and the potential key regulators involved. Life sciences. vol 270. 2021-03-11. PMID:33482188. |
cell proliferation was examined by mtt, cell cycle and apoptosis were detected by flow cytometry. |
2021-03-11 |
2023-08-13 |
human |
| Ying Zhang, Xiangyang Cao, Peifeng Li, Yanan Fan, Leilei Zhang, Wuyin Li, Youwen Li. PSMC6 promotes osteoblast apoptosis through inhibiting PI3K/AKT signaling pathway activation in ovariectomy-induced osteoporosis mouse model. Journal of cellular physiology. vol 235. issue 7-8. 2021-03-10. PMID:32017075. |
further, mtt, bromodeoxyuridine, and flow cytometry assays revealed that psmc6 inhibition promoted the progression of cell cycle and cell proliferation, whereas, psmc6 overexpression promoted the apoptosis and inhibited cell cycle progression and cell proliferation in vitro. |
2021-03-10 |
2023-08-13 |
mouse |
| Shokoofe Noori, Mostafa Rezaei Tavirani, Niloofar Deravi, Mohammad Ismaiil Mahboobi Rabbani, Afshin Zargh. Naringenin Enhances the Anti-Cancer Effect of Cyclophosphamide against MDA-MB-231 Breast Cancer Cells Via Targeting the STAT3 Signaling Pathway. Iranian journal of pharmaceutical research : IJPR. vol 19. issue 3. 2021-03-10. PMID:33680016. |
apoptosis was measured via flowcytometric analysis of annexin v binding and cell viability was assessed via mtt assay. |
2021-03-10 |
2023-08-13 |
Not clear |
| Yu Jian, Qi Fa. Long non-coding RNA SNHG7 facilitates pancreatic cancer progression by regulating the miR-146b-5p/Robo1 axis. Experimental and therapeutic medicine. vol 21. issue 4. 2021-03-10. PMID:33680120. |
moreover, cell viability and apoptosis were assessed by mtt and flow cytometry assays, respectively. |
2021-03-10 |
2023-08-13 |
mouse |
| Xiao Liu, Zheng Li, Ming Li, Jingxiu Chai, Shan He, Jinfeng Wu, Jinhua X. Icariside II overcomes BRAF inhibitor resistance in melanoma by inducing ROS production and inhibiting MITF. Oncology reports. vol 44. issue 1. 2021-03-08. PMID:32319656. |
in the present study, we determined by mtt, flow cytometry and western blotting, respectively that is potentiated the plx4032‑induced downregulation of cell viability and increase in apoptosis and autophagy in braf inhibitor‑resistant melanoma. |
2021-03-08 |
2023-08-13 |
Not clear |
| Yi-Feng Yuan, Wen-Xiong Zhu, Tao Liu, Ju-Qiao He, Qing Zhou, Xing Zhou, Xi Zhang, Jing Yan. Cyclopamine functions as a suppressor of benign prostatic hyperplasia by inhibiting epithelial and stromal cell proliferation via suppression of the Hedgehog signaling pathway. International journal of molecular medicine. vol 46. issue 1. 2021-03-05. PMID:32319534. |
cell proliferation, cell cycle and apoptosis were analyzed using an mtt assay and flow cytometry. |
2021-03-05 |
2023-08-13 |
rat |
| Chuhai Xie, Binwei Chen, Boyi Wu, Jianhong Guo, Yulong Shi, Yanming Ca. CircSAMD4A regulates cell progression and epithelial‑mesenchymal transition by sponging miR‑342‑3p via the regulation of FZD7 expression in osteosarcoma. International journal of molecular medicine. vol 46. issue 1. 2021-03-05. PMID:32319545. |
mtt assay and flow cytometry were used to detect cell cytotoxicity and apoptosis, respectively. |
2021-03-05 |
2023-08-13 |
mouse |
| H N Gao, F Z Ren, P C Wen, L X Xie, R Wang, Z N Yang, Y X L. Yak milk-derived exosomal microRNAs regulate intestinal epithelial cells on proliferation in hypoxic environment. Journal of dairy science. vol 104. issue 2. 2021-03-05. PMID:33246613. |
in vitro assay of the role of bta-mir-34a on survival of iec-6 in hypoxia by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (mtt) confirmed its effectiveness to significantly increase iec-6 survival up to 13% for 12 h, and up to 9.5% for 24 h. investigation on the regulatory relationship between bta-mirna-34a and the hypoxia-inducible factor/apoptosis signaling pathway provided insights into the possible mechanisms by which bta-mir-34a activated the hypoxia-inducible factor and apoptosis signaling pathway, thus promoting iec-6 survival. |
2021-03-05 |
2023-08-13 |
Not clear |
| C J Wei, F Hua, Y H Chen, Z W Zhang, Z Y She. Muscone alleviates myocardial ischemia-reperfusion injury via inhibition of oxidative stress and enhancement of SIRT3. Journal of biological regulators and homeostatic agents. vol 35. issue 1. 2021-03-05. PMID:33480219. |
mtt assay and tunel assay were performed to investigate h9c2 viability and apoptosis, respectively. |
2021-03-05 |
2023-08-13 |
rat |
| Long Jin, Yu-Liang Pan, Jun Zhang, Pei-Guo Ca. LncRNA HOTAIR recruits SNAIL to inhibit the transcription of HNF4α and promote the viability, migration, invasion and EMT of colorectal cancer. Translational oncology. vol 14. issue 4. 2021-03-05. PMID:33588137. |
the cell viability, migration, invasion and apoptosis rate were evaluated using mtt, brdu,transwell and flow cytometryexperiments. |
2021-03-05 |
2023-08-13 |
mouse |
| Thoria Diab, Samar Sami AlKafaas, Thanaa Ibrahim Shalaby, Mohamed Hessie. Dexamethasone simulates the anticancer effect of nano-formulated paclitaxel in breast cancer cells. Bioorganic chemistry. vol 99. 2021-03-01. PMID:32240873. |
cells viability (assessed by mtt assay), apoptosis (assessed by flow cytometry) and the expression of ptx resistance gene (trx1) and ptx metabolizing genes (cyp2c8 and cyp3a4) were investigated. |
2021-03-01 |
2023-08-13 |
Not clear |