Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Bendan Long, Yun Wan, Siqin Zhang, Lisa L. LncRNA XIST protects podocyte from high glucose-induced cell injury in diabetic nephropathy by sponging miR-30 and regulating AVEN expression. Archives of physiology and biochemistry. 2021-05-06. PMID:33332155. |
further wb (western blot), mtt (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide), and flow cytometry confirmed that xist could reverse the expression of aven and ameliorate hg-induced apoptosis. |
2021-05-06 |
2023-08-13 |
Not clear |
Di Lu, Lingling Sun, Zhengjun Li, Zhen M. lncRNA EZR‑AS1 knockdown represses proliferation, migration and invasion of cSCC via the PI3K/AKT signaling pathway. Molecular medicine reports. vol 23. issue 1. 2021-05-05. PMID:33236153. |
cell viability, proliferation, migration, invasion and apoptosis were assessed using mtt, plate cloning, wound healing, transwell and flow cytometry assays, respectively. |
2021-05-05 |
2023-08-13 |
human |
Hui Zhao, Ying Gu, Hai Che. Propofol ameliorates endotoxin‑induced myocardial cell injury by inhibiting inflammation and apoptosis via the PPARγ/HMGB1/NLRP3 axis. Molecular medicine reports. vol 23. issue 3. 2021-05-05. PMID:33398367. |
cell viability was measured using an mtt assay, and the levels of cell apoptosis were determined using flow cytometry, jc‑1 staining (mitochondrial membrane potential) and caspase‑3 activity assays. |
2021-05-05 |
2023-08-13 |
rat |
Chuihua Sun, Ting Xiao, Ying Xiao, Yunbao L. Silencing of long non‑coding RNA NEAT1 inhibits hepatocellular carcinoma progression by downregulating SMO by sponging microRNA‑503. Molecular medicine reports. vol 23. issue 3. 2021-05-05. PMID:33398379. |
mtt and flow cytometry assays were used to investigate cell viability and apoptosis, respectively, while transwell assays were performed to investigate cell invasion and migration. |
2021-05-05 |
2023-08-13 |
Not clear |
Xiaoliang Wang, Wenrong Li, Yanhong Chen, Lijuan Zho. Long non‑coding RNA SNHG14 affects the proliferation and apoptosis of childhood acute myeloid leukaemia cells by modulating the miR‑193b‑3p/MCL1 axis. Molecular medicine reports. vol 23. issue 2. 2021-05-04. PMID:33300066. |
aml cell viability and apoptosis were assessed using mtt and flow cytometry analyses. |
2021-05-04 |
2023-08-13 |
Not clear |
Hebing Xie, Gang Xu, Yuqi Gao, Zhibin Yua. hCINAP serves a critical role in hypoxia‑induced cardiomyocyte apoptosis via modulating lactate production and mitochondrial‑mediated apoptosis signaling. Molecular medicine reports. vol 23. issue 2. 2021-05-04. PMID:33300073. |
mtt and apoptosis assays were conducted to detect cell viability and apoptosis, respectively. |
2021-05-04 |
2023-08-13 |
human |
Lun Liu, Ruijing Wang, Zian Zhang, Xiangda Wan. Nasopharyngeal carcinoma‑associated gene 6 inhibits cell viability, migration, invasion and induces apoptosis in osteosarcoma cells by inactivating the Wnt/β‑catenin signaling pathway. Molecular medicine reports. vol 23. issue 2. 2021-05-04. PMID:33300077. |
mtt, wound healing, transwell and flow cytometry assays were performed to analyze cell viability, migration, invasion and apoptosis, respectively. |
2021-05-04 |
2023-08-13 |
mouse |
Fengyu Wang, Fengli Wang, Shengyu Zhang, Xiaogang X. MicroRNA-325 inhibits the proliferation and induces the apoptosis of T cell acute lymphoblastic leukemia cells in a BAG2-dependent manner. Experimental and therapeutic medicine. vol 21. issue 6. 2021-05-04. PMID:33936287. |
the effects of mir-325 mimic and bag2 downregulation on the proliferation and apoptosis were assessed by an mtt assay, flow cytometry and western blot analysis. |
2021-05-04 |
2023-08-13 |
Not clear |
Ting Chen, Chunyan Zhu, Chongyang Y. LncRNA CYTOR attenuates sepsis-induced myocardial injury via regulating miR-24/XIAP. Cell biochemistry and function. vol 38. issue 7. 2021-05-03. PMID:32181504. |
after up-regulation or down-regulation of cytor and mir-24 expression in the h9c2 cells, and the viability of the cells was detected via mtt assay, and cell apoptosis was detected by tunel assay. |
2021-05-03 |
2023-08-13 |
mouse |
Da Ni, Jiping Teng, Youshuang Cheng, Zhijun Zhu, Bufeng Zhuang, Zhiyin Yan. MicroRNA‑92a promotes non‑small cell lung cancer cell growth by targeting tumor suppressor gene FBXW7. Molecular medicine reports. vol 22. issue 4. 2021-05-03. PMID:32945381. |
cell viability and cell apoptosis were determined using an mtt assay and flow cytometry, respectively. |
2021-05-03 |
2023-08-13 |
Not clear |
Meng Wang, Xiaoxia Wang, Wenfeng Li. MicroRNA‑130a‑3p promotes the proliferation and inhibits the apoptosis of cervical cancer cells via negative regulation of RUNX3. Molecular medicine reports. vol 22. issue 4. 2021-05-03. PMID:32945424. |
the proliferation, apoptosis and migration and invasion abilities of cc cells were then measured using mtt, flow cytometry, wound‑healing and transwell assays, respectively. |
2021-05-03 |
2023-08-13 |
mouse |
Xiaoqiao Shi, Zhiwen Liu, Junwei L. Protective effects of dexmedetomidine on hypoxia/reoxygenation injury in cardiomyocytes by regulating the CHOP signaling pathway. Molecular medicine reports. vol 22. issue 4. 2021-04-30. PMID:32945482. |
cell viability, apoptosis and lactate dehydrogenase (ldh) levels were determined by mtt, flow cytometry and 2,4‑dinitrophenylhydrazine colorimetric assays, respectively. |
2021-04-30 |
2023-08-13 |
Not clear |
Ya Zhou, Xianguo Li, Dong Zhao, Xinya Li, Jianjun Da. Long non‑coding RNA MEG3 knockdown alleviates hypoxia‑induced injury in rat cardiomyocytes via the miR‑325‑3p/TRPV4 axis. Molecular medicine reports. vol 23. issue 1. 2021-04-30. PMID:33179099. |
cell viability and apoptosis were assessed by performing an mtt assay and flow cytometry, respectively. |
2021-04-30 |
2023-08-13 |
rat |
Xiaolin Wang, Jialun Shi, Zhigao Niu, Jianwu Wang, Wenping Zhan. MiR-216a-3p regulates the proliferation, apoptosis, migration, and invasion of lung cancer cells via targeting COPB2. Bioscience, biotechnology, and biochemistry. vol 84. issue 10. 2021-04-28. PMID:32619135. |
after transfection, cell viability, migration, invasion, proliferation, and apoptosis were detected by mtt, scratch, transwell, colony formation, and flow cytometry. |
2021-04-28 |
2023-08-13 |
Not clear |
Liansheng Sha, Deying Ma, Cuili Che. Exosome-mediated Hic-5 regulates proliferation and apoptosis of osteosarcoma via Wnt/β-catenin signal pathway. Aging. vol 12. issue 23. 2021-04-27. PMID:33310972. |
the effect of hic-5 on cell viability, proliferation and apoptosis were assessed by mtt, edu kit and flow cytometry. |
2021-04-27 |
2023-08-13 |
Not clear |
Jiong Zhang, Xiaojun Den. Effects of miR-599 targeting YAP1 on proliferation, invasion and apoptosis of bladder urothelial carcinoma cells. Experimental and molecular pathology. vol 118. 2021-04-27. PMID:33359177. |
j82 cells cultured in vitro were divided into mir-nc group (transfected with analog negative control mir-nc), mir-599 group (transfected with mir-599 analog), mir-599 + pcdna3.1 group (co transfected with mir-599 analog and pcdna3.1 empty vector), mir-599 + pcdna3.1-yap1 group (co transfected with mir-599 analog and pcdna3.1-yap1 over expression vector), the targeting relationship between mir-599 and yap1 was detected by double luciferase reporter gene assay, the expression level of mir-599 was detected by real-time fluorescence quantitative pcr, the expression of yap1 was detected by western blot, cell proliferation was detected by mtt method, cell invasion was detected by transwell's cell experiment, and apoptosis was detected by flow cytometry. |
2021-04-27 |
2023-08-13 |
Not clear |
Jin Li, Jingdong He, Yuan Wang, Yongqian Shu, Jianwei Zho. SMC1 promotes proliferation and inhibits apoptosis through the NF‑κB signaling pathway in colorectal cancer. Oncology reports. vol 42. issue 4. 2021-04-26. PMID:31524239. |
as a result, cell viability, proliferation, invasion and migration were suppressed in transduced sw620 cells but enhanced in sw480 cells, as determined using mtt, colony formation and transwell assays; conversely, flow cytometric analysis revealed that cell apoptosis was increased in sw620 cells and inhibited in sw480 cells following lentiviral infection. |
2021-04-26 |
2023-08-13 |
mouse |
Yunsheng Xu, Qianwen Zhang, Fan Lin, Li Zhu, Fangfang Huang, Liang Zhao, Rongying O. Casiopeina II‑gly acts on lncRNA MALAT1 by miR‑17‑5p to inhibit FZD2 expression via the Wnt signaling pathway during the treatment of cervical carcinoma. Oncology reports. vol 42. issue 4. 2021-04-26. PMID:31524268. |
cell viability and apoptosis were determined via mtt assays, edu staining and flow cytometry. |
2021-04-26 |
2023-08-13 |
Not clear |
Mingyue Zheng, Yaochi W. Piceatannol suppresses proliferation and induces apoptosis by regulation of the microRNA‑21/phosphatase and tensin homolog/protein kinase B signaling pathway in osteosarcoma cells. Molecular medicine reports. vol 22. issue 5. 2021-04-26. PMID:32901863. |
herein, we performed a mtt assay and flow cytometric analysis to determine cell viability and apoptosis in os cells treated with pice, respectively. |
2021-04-26 |
2023-08-13 |
human |
Yan Zhao, Jianghui Liu, Liang Li. Artesunate inhibits lung cancer cells via regulation of mitochondrial membrane potential and induction of apoptosis. Molecular medicine reports. vol 22. issue 4. 2021-04-26. PMID:32945409. |
the inhibitory effect of art on the growth of a549 lung cancer cells was detected by the mtt assay, and flow cytometry was utilized to determine cell cycle progression, apoptosis, mitochondrial membrane potential, as well as the expression of bcl‑2 and bax proteins in a549 cells after art treatment for 24 h. |
2021-04-26 |
2023-08-13 |
human |