| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kai Zheng, Ying Wan. MiR-193a-3p Promotes Fracture Healing via Targeting PTEN Gene. Molecular biotechnology. vol 63. issue 7. 2021-06-11. PMID:33813678. |
mtt assay and flow cytometry were used to detect cell viability and apoptosis in the mouse osteoblastic cell line mc3t3-e1. |
2021-06-11 |
2023-08-13 |
mouse |
| Jie Hu, Shu-Wen Dong, Yinghua Pei, Juan Wang, Jie Zhang, Xiu-Ping We. LncRNA MITA1 promotes gefitinib resistance by inducing autophagy in lung cancer cells. Biochemical and biophysical research communications. vol 551. 2021-06-10. PMID:33714755. |
subsequently, lncrna mita1 mediated effect on cell viability and apoptosis were studied using the mtt and flow cytometry assays. |
2021-06-10 |
2023-08-13 |
Not clear |
| Shivakumar Belur, Narasimhappagari Jagadeesh, Bale M Swamy, Shashikala R Inamda. A core fucose specific lectin from Cephalosporium curvulum induces cellular apoptosis in hepatocellular and pancreatic cancer cells and effective in detecting AFP. Glycoconjugate journal. vol 37. issue 4. 2021-06-09. PMID:32367479. |
effect of csl, lca and aol on panc-1 and hepg2 cells was determined by mtt assay and all the three lectins inhibited the cell growth which could be blocked by mucin, cell cycle analysis revealed that csl increased hypodiploid hepg2 cell population indicating cellular apoptosis. |
2021-06-09 |
2023-08-13 |
Not clear |
| Lin Zhang, Hui Yang, Wen-Juan Li, Ye-Hui Li. LncRNA MALAT1 Promotes OGD-Induced Apoptosis of Brain Microvascular Endothelial Cells by Sponging miR-126 to Repress PI3K/Akt Signaling Pathway. Neurochemical research. vol 45. issue 9. 2021-06-08. PMID:32591985. |
cell viability and cell apoptosis were assessed by mtt assay and flow cytometry, respectively. |
2021-06-08 |
2023-08-13 |
human |
| Adriely Maria Oliveira Rocha, Fernanda Severo Sabedra Sousa, Victoria Mascarenhas Borba, Taiana S Munchen, Julliano Guerin Leal, Oscar Endrigo Dorneles Rodrigues, Mariana G Fronza, Lucielli Savegnago, Tiago Collares, Fabiana Kömmling Seixa. Evaluation of the effect of synthetic compounds derived from azidothymidine on MDA-MB-231 type breast cancer cells. Bioorganic & medicinal chemistry letters. vol 30. issue 17. 2021-06-08. PMID:32738968. |
the inhibitory effect of azt and its derivatives (7m and 7r) was determined by the mtt assay (6.25, 12.5, 25, 50 and 100 μm in 24 and 48 h time points), meanwhile the induction of apoptosis and the cell cycle phases was investigated by flow cytometry. |
2021-06-08 |
2023-08-13 |
human |
| Yue Zhang, Yunfei Bia. Long Non-Coding RNA SNHG8 Plays a Key Role in Myocardial Infarction Through Affecting Hypoxia-Induced Cardiomyocyte Injury. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2021-06-08. PMID:32772038. |
mtt (3-(45)-dimethylthiahiazo (-z-y 1)-35-diphenytetrazoliumromide) assay was used to detect cell viability and flow cytometry analysis was used to detect cell apoptosis. |
2021-06-08 |
2023-08-13 |
Not clear |
| Yigang Wang, Shijuan Xu, Lu Wang, Juanni Liu, Juan Wang, Jun Zho. Long noncoding RNA H19 promotes vincristine resistance in multiple myeloma by targeting Akt. Cellular and molecular biology (Noisy-le-Grand, France). vol 66. issue 6. 2021-06-07. PMID:33040789. |
mtt assay, flow cytometry assay, western-blotting assay and luciferase assay were used to analyze the growth, apoptosis and protein phosphorylation levels of drug-resistant rpmi 8226/vcr and rpmi 8226 cells after vcr treatment and plasmid transprinting. |
2021-06-07 |
2023-08-13 |
Not clear |
| Wensi Chen, Shiping He, Daoman Xian. Hypoxia-induced retinal pigment epithelium cell-derived bFGF promotes the migration and angiogenesis of HUVECs through regulating TGF-β1/smad2/3 pathway. Gene. vol 790. 2021-06-07. PMID:33964379. |
after cell culture in hypoxia conditions, the cell viability, apoptosis, and the expressions of bfgf and vascular endothelial growth factor a (vegfa) in human rpes were detected by 3-(4, 5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt), flow cytometry, western blot, rt-qpcr, or elisa. |
2021-06-07 |
2023-08-13 |
human |
| Venkatesh Ravula, Yu-Lun Lo, Yi-Ting Wu, Chien-Wen Chang, Srilakshmi V Patri, Li-Fang Wan. Arginine-tocopherol bioconjugated lipid vesicles for selective pTRAIL delivery and subsequent apoptosis induction in glioblastoma cells. Materials science & engineering. C, Materials for biological applications. vol 126. 2021-06-07. PMID:34082988. |
induction of apoptosis in u87 cells exposed to at-based/ptrail plasmid is evaluated by mtt assay as well as annexin v-propidium iodide dual-staining assay. |
2021-06-07 |
2023-08-13 |
Not clear |
| Cun Gao, Rui Dong, Yongmeng Li, Jinghui Liang, Hui Tia. MCTS1 promotes the development of lung adenocarcinoma by regulating E2F1 expression. Oncology letters. vol 22. issue 1. 2021-06-05. PMID:34079590. |
the mtt, colony formation, edu, flow cytometry, wound healing and transwell assays were performed to assess the proliferation, apoptosis, migration and invasion of luad cells. |
2021-06-05 |
2023-08-13 |
Not clear |
| Minggang Cheng, Yichen Guo, Weichuan Zhong, Xueyan Chen, Guangzhou Gu. Abnormal Expression of microRNA-296-3p in Type 2 Diabetes Patients and its Role in Pancreatic β-Cells Function by Targeting Tensin Homolog Deleted on Chromosome Ten. Biochemical genetics. 2021-06-04. PMID:34085179. |
moreover, min6 cells were induced by 5 mg/dl ua and the cell proliferation, apoptosis, and insulin release were evaluated using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay, flow cytometry and glucose-stimulated insulin secretion (gsis), respectively. |
2021-06-04 |
2023-08-13 |
Not clear |
| Bo Qiu, Xiongfeng Xu, Peng Yi, Yarong Ha. Curcumin reinforces MSC-derived exosomes in attenuating osteoarthritis via modulating the miR-124/NF-kB and miR-143/ROCK1/TLR9 signalling pathways. Journal of cellular and molecular medicine. vol 24. issue 18. 2021-06-03. PMID:32776418. |
accordingly, by conducting mtt and flow cytometry assays, we found that the exosomes derived from curcumin-treated mscs helped to maintain the viability while inhibiting the apoptosis of model oa cells. |
2021-06-03 |
2023-08-13 |
mouse |
| Salma Aboelela, Abeer Ashmawy, Sabry Shaarawy, Mohammed El-Hefny, Amina Medha. Telomerase as a Possible Candidate Targeting Therapy in Different Breast Cancer Cell Lines. Asian Pacific journal of cancer prevention : APJCP. vol 21. issue 8. 2021-06-03. PMID:32856851. |
the present work investigated the effects of telomerase inhibition by sirna on breast cancer cell lines and studied the feasibility of whether the combined effect of doxorubicin with sirna treatment on breast cancer cells potentiates a rapid cellular response to the cytotoxic effect of chemotherapy. methods: this study was performed on luminal a (mcf-7), triple negative (mda-mb-468), and her-2/neu (skbr-3) human breast cancer cell lines, wherein telomerase activity inhibition by htert sirna and doxorubicin was detected by measuring telomerase activity using telomeric repeat amplification protocol (trap assay), assessing cell viability through mtt assay, and evaluating apoptosis through scanning electron microscopy (sem) and through estimating caspase-3 and -8 activities using enzyme-linked immunosorbent assay (elisa). |
2021-06-03 |
2023-08-13 |
human |
| Wei He, Songyuan Chi, Xing Jin, Jieyu Lu, Wei Zheng, Jie Yan, Duo Zhan. Long Non-Coding RNA BACE1-AS Modulates Isoflurane-Induced Neurotoxicity to Alzheimer's Disease Through Sponging miR-214-3p. Neurochemical research. vol 45. issue 10. 2021-06-01. PMID:32681443. |
the proliferation and apoptosis of aβ-treated sk-n-sh and sk-n-as cells were determined via 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-h-tetrazolium bromide (mtt) or flow cytometry assays, respectively. |
2021-06-01 |
2023-08-13 |
Not clear |
| Furong Song, Jun Liu, Yawei Feng, Yi Ji. Propofol‑induced HOXA11‑AS promotes proliferation, migration and invasion, but inhibits apoptosis in hepatocellular carcinoma cells by targeting miR‑4458. International journal of molecular medicine. vol 46. issue 3. 2021-06-01. PMID:32705160. |
mtt assay, flow cytometry analysis and transwell assays were conducted to examine cell proliferation, apoptosis, migration and invasion, respectively. |
2021-06-01 |
2023-08-13 |
human |
| Fangdong Guo, Xiaoyu Zhu, Qingquan Zhao, Qirong Huan. miR‑589‑3p sponged by the lncRNA TINCR inhibits the proliferation, migration and invasion and promotes the apoptosis of breast cancer cells by suppressing the Akt pathway via IGF1R. International journal of molecular medicine. vol 46. issue 3. 2021-06-01. PMID:32705168. |
the effects of tincr and mir‑589‑3p on the proliferation, apoptosis, migratory and invasive abilities of some breast cancer cell lines were detected by mtt assay, flow cytometry, wound healing assay and transwell assay. |
2021-06-01 |
2023-08-13 |
Not clear |
| Zhongjin Liu, Haiyan Zhang, Lihui Sun, Kunjie Zhu, Weiya Lan. miR-29c-3p Increases Cell Viability and Suppresses Apoptosis by Regulating the TNFAIP1/NF-κB Signaling Pathway via TNFAIP1 in Aβ-Treated Neuroblastoma Cells. Neurochemical research. vol 45. issue 10. 2021-06-01. PMID:32712875. |
besides, cell proliferation and apoptosis rate were determined by 3-(4, 5-dimethyl-2-thiazolyl)-2, 5-diphenyl-2-h-tetrazolium bromide (mtt) assay and flow cytometry analysis, respectively. |
2021-06-01 |
2023-08-13 |
Not clear |
| Tulin Ozkan, Yalda Hekmatshoar, Hanife Pamuk, Merve Ozcan, Guler Yaman, Gulsah Ceylan Yagiz, Cigdem Akdemir, Asuman Sungurogl. Cytotoxic effect of 6-Shogaol in Imatinib sensitive and resistant K562 cells. Molecular biology reports. vol 48. issue 2. 2021-06-01. PMID:33515349. |
cell viability and apoptosis were investigated with spectrophotometric mtt assay and flow cytometric annexin v staining, respectively. |
2021-06-01 |
2023-08-13 |
Not clear |
| Yanfa Dai, Jingyuan Nie, Zhongqin Luo, Dongsong Ni. Expression profile analysis of a new testis-specifically expressed gene C17ORF64 and its association with cell apoptosis in MCF-7 cells. Molecular biology reports. vol 48. issue 2. 2021-06-01. PMID:33566224. |
c17orf64 overexpression not only promoted cell apoptosis in mcf-7 cells, but also significantly decreased cell viability via mtt assay. |
2021-06-01 |
2023-08-13 |
mouse |
| Xifeng Tao, Yafei Fang, Chen Hu. Long non-coding RNA Rian protects against experimental bronchopulmonary dysplasia by sponging miR-421. Experimental and therapeutic medicine. vol 22. issue 1. 2021-06-01. PMID:34055080. |
cell growth and apoptosis were evaluated using an mtt assay and flow cytometry, respectively. |
2021-06-01 |
2023-08-13 |
mouse |