| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bin Lin, Jing Xu, Feng Wang, Jiaxiang Wang, Hui Zhao, Deguang Fen. LncRNA XIST promotes myocardial infarction by regulating Aging. vol 12. issue 8. 2021-02-23. PMID:32315985. |
mtt assay and flow cytometry were used to determine proliferation and apoptosis respectively. |
2021-02-23 |
2023-08-13 |
mouse |
| Nerella Sridhar Goud, Venkata Krishna Kanth Makani, Jakkula Pranay, Ravi Alvala, Insaf A Qureshi, Pardeep Kumar, Rose Dawn Bharath, Chandana Nagaraj, Suresh Yerramsetty, Manika Pal-Bhadra, Mallika Alval. Synthesis, Bioorganic chemistry. vol 97. 2021-02-22. PMID:32106038. |
synthesis, in present study, a new series of 4, 7-disubstituted coumarin derivatives (7a-y) have been synthesized as galectin-1 targeting apoptosis inducing agents and evaluated for their in vitro cytotoxic potentials against a panel of selected human cancer cell lines namely, brest (mcf7), ovarian (skov3), prostate (pc-3 & du145) and normal embryonic kidney (hek293t) cells, using mtt assay. |
2021-02-22 |
2023-08-13 |
human |
| Long Cheng, Zihe Xing, Peng Zhang, Wuqin X. Long non-coding RNA LINC00662 promotes proliferation and migration of breast cancer cells via regulating the miR-497-5p/EglN2 axis. Acta biochimica Polonica. vol 67. issue 2. 2021-02-19. PMID:32558530. |
moreover, the mtt assay, wound-healing assay, colony-forming assay and transwell assay were employed in mda-mb-157 cells to detect the effect of linc00662 on cell apoptosis, invasion, migration and proliferation, respectively. |
2021-02-19 |
2023-08-13 |
human |
| Alicia Arranz-Romera, Maria Hernandez, Patricia Checa-Casalengua, Alfredo Garcia-Layana, Irene T Molina-Martinez, Sergio Recalde, Michael J Young, Budd A Tucker, Rocío Herrero-Vanrell, Patricia Fernandez-Robredo, Irene Bravo-Osun. A Safe GDNF and GDNF/BDNF Controlled Delivery System Improves Migration in Human Retinal Pigment Epithelial Cells and Survival in Retinal Ganglion Cells: Potential Usefulness in Degenerative Retinal Pathologies. Pharmaceuticals (Basel, Switzerland). vol 14. issue 1. 2021-02-18. PMID:33440745. |
in vitro release, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) cell viability, terminal deoxynucleotidyl transferase (tdt) deoxyuridine dutp nick-end labelling (tunel) apoptosis, functional wound healing migration (arpe-19; migration), and (rf/6a; angiogenesis) assays were conducted. |
2021-02-18 |
2023-08-13 |
mouse |
| Jinchuan Chen, Rujie Qi. MicroRNA‑138‑5p regulates the development of spinal cord injury by targeting SIRT1. Molecular medicine reports. vol 22. issue 1. 2021-02-16. PMID:32319664. |
then, mtt assay, flow cytometry and elisa experiments were performed to analyze cell viability, apoptosis, and the levels of tumor necrosis factor‑α, interleukin (il)‑1β and il‑6. |
2021-02-16 |
2023-08-13 |
rat |
| Yongli Hu, Bing Wang, Lie Wang, Zhenran Wang, Zhiyuan Jian, Lin Den. Mammalian STE20‑like kinase 1 regulates pancreatic cancer cell survival and migration through Mfn2‑mediated mitophagy. Molecular medicine reports. vol 22. issue 1. 2021-02-16. PMID:32377725. |
moreover, mst1 overexpression in panc‑1 cells led to increased apoptosis as determined by mtt and tunel assays and inhibited cellular migration. |
2021-02-16 |
2023-08-13 |
Not clear |
| Qiang Xue, Dong Yang, Jilei Zhang, Pin Gan, Chunrong Lin, Yibing Lu, Weihua Zhang, Li Zhang, Xuefeng Guan. USP7, negatively regulated by miR-409-5p, aggravates hypoxia-induced cardiomyocyte injury. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. vol 129. issue 3. 2021-02-16. PMID:33241864. |
after usp7 and mir-409-5p were selectively regulated in h9c2 cells, the inflammatory response, apoptosis, and cell viability were detected by elisa, flow cytometry, and mtt assay, respectively. |
2021-02-16 |
2023-08-13 |
rat |
| Yongkun Wang, Tingting Liang, Yao Wang, Yan Huang, Ye L. Long non-coding RNA AK093407 promotes proliferation and inhibits apoptosis of human osteosarcoma cells via STAT3 activation. American journal of cancer research. vol 7. issue 4. 2021-02-12. PMID:28469961. |
cell proliferation, viability, and apoptosis were measured using ki-67 proliferation assay, mtt assay, and annexin v/pi staining assay, respectively. |
2021-02-12 |
2023-08-13 |
human |
| Yao Sh. MEG3 regulates apoptosis of adipose‑derived stem cells. Molecular medicine reports. vol 21. issue 6. 2021-02-12. PMID:32323784. |
meg3 was overexpressed in adscs and these cells were evaluated for viability, tp53 expression, apoptosis, morphology, and bax and bcl‑2 expression by performing mtt assays, reverse transcription‑quantitative pcr, flow cytometry analysis and western blotting. |
2021-02-12 |
2023-08-13 |
Not clear |
| Sujin Kim, Suji Kim, Ae-Rang Hwang, Hyoung Chul Choi, Ji-Yun Lee, Chang-Hoon Wo. Apelin-13 Inhibits Methylglyoxal-Induced Unfolded Protein Responses and Endothelial Dysfunction via Regulating AMPK Pathway. International journal of molecular sciences. vol 21. issue 11. 2021-02-12. PMID:32517197. |
mgo-induced er stress and apoptosis were determined by immunoblotting and mtt assay in huvecs. |
2021-02-12 |
2023-08-13 |
mouse |
| Marjan Aghajani, Ahad Mokhtarzadeh, Leili Aghebati-Maleki, Behzad Mansoori, Ali Mohammadi, Sahar Safaei, Zahra Asadzadeh, Khalil Hajiasgharzadeh, Vahid Khaze Shahgoli, Behzad Baradara. CD133 suppression increases the sensitivity of prostate cancer cells to paclitaxel. Molecular biology reports. vol 47. issue 5. 2021-02-11. PMID:32246247. |
to measure the cell viability, migratory capacity, cscs properties, invasive potential, apoptosis and cell cycle progression of the cells, the mtt, wound healing, spheroid assay, colony formation assay, dapi staining and flow cytometry assays were applied in the lncap cell line, respectively. |
2021-02-11 |
2023-08-13 |
Not clear |
| Yu Liao, Ziyan Wang, Lixin Wang, Yanzhao Lin, Ziyi Ye, Xufang Zeng, Fangning We. MicroRNA-27a-3p directly targets FosB to regulate cell proliferation, apoptosis, and inflammation responses in immunoglobulin a nephropathy. Biochemical and biophysical research communications. vol 529. issue 4. 2021-02-11. PMID:32819575. |
methylthiazolyldiphenyl-tetrazolium bromide (mtt), flow cytometry, real-time polymerase chain reaction, western blot, and enzyme-linked immunosorbent assays were used to verify the regulatory effects of mir-27a-3p and its inhibition on cell proliferation, apoptosis, and release of inflammatory factors in podocytes and hk2 cells. |
2021-02-11 |
2023-08-13 |
human |
| Darya Javadrashid, Reza Mohammadzadeh, Amir Baghbanzadeh, Sahar Safaee, Mohammad Amini, Ziba Lotfi, Elham Baghbani, Vahid Khaze Shahgoli, Behzad Baradara. Simultaneous microRNA-612 restoration and 5-FU treatment inhibit the growth and migration of human PANC-1 pancreatic cancer cells. EXCLI journal. vol 20. 2021-02-11. PMID:33564285. |
to confirm mtt results and to evaluate the quantitative effect of apoptosis induction flow cytometry test was used and in order to confirm apoptosis test results and cell cycle arrest evaluation dapi staining and cell, cycle tests were conducted, respectively. |
2021-02-11 |
2023-08-13 |
human |
| Ding Wang, Zhiying Li, Hui Li, Jiao Lu, Qi Qi. Long non-coding RNA SNHG20 promotes ovarian cancer development by targeting microRNA-338-3p to regulate MCL1 expression. Oncology letters. vol 21. issue 2. 2021-02-10. PMID:33552251. |
mtt assay, flow cytometry and transwell migration and invasion assays were used to assess cell proliferation, apoptosis, migration and invasion, respectively. |
2021-02-10 |
2023-08-13 |
mouse |
| Maoshu Zhu, Yulong Wu, Zhaowei Wang, Minghua Lin, Bin Su, Chunyang Li, Fulong Liang, Xinjiang Che. miR-128-3p serves as an oncogenic microRNA in osteosarcoma cells by downregulating ZC3H12D. Oncology letters. vol 21. issue 2. 2021-02-10. PMID:33552270. |
mtt, colony formation and flow cytometry assays were also used to analyze the effect of mir-128-3p on cell proliferation and apoptosis. |
2021-02-10 |
2023-08-13 |
human |
| Sen Yang, Jia Liu, Jianxia Jiao, Linjun Jia. Ar-Turmerone Exerts Anti-proliferative and Anti-inflammatory Activities in HaCaT Keratinocytes by Inactivating Hedgehog Pathway. Inflammation. vol 43. issue 2. 2021-02-08. PMID:31773440. |
the effects of ar-turmerone alone or combined with recombinant human sonic hedgehog (rhshh) on cell proliferation, apoptosis, and inflammatory cytokine secretion were explored by mtt, flow cytometry analysis, and elisa, respectively. |
2021-02-08 |
2023-08-13 |
mouse |
| Jia Jin, Leiping Wang, Zhonghua Tao, Jian Zhang, Fangfang Lv, Junning Cao, Xichun H. PDGFD induces ibrutinib resistance of diffuse large B‑cell lymphoma through activation of EGFR. Molecular medicine reports. vol 21. issue 5. 2021-02-08. PMID:32186759. |
the apoptosis of the dlbcl/ibrutinib‑resistant strains was examined using mtt and flow cytometry assays. |
2021-02-08 |
2023-08-13 |
Not clear |
| Wei Tian, Zhi-Wei Wang, Bao-Ming Yuan, Yong-Ge Ba. Calycosin induces apoptosis in osteosarcoma cell line via ERβ‑mediated PI3K/Akt signaling pathways. Molecular medicine reports. vol 21. issue 6. 2021-02-08. PMID:32236598. |
human os mg‑63 cells were treated with various concentrations of calycosin, and mtt and flow cytometry assays were used to assess the effects of calycosin on cellular proliferation and apoptosis. |
2021-02-08 |
2023-08-13 |
human |
| Qiu Yu, Xiao-Ping Xu, Xin-Min Yin, Xiang-Qun Pen. miR-155-5p increases the sensitivity of liver cancer cells to adriamycin by regulating ATG5-mediated autophagy. Neoplasma. vol 68. issue 1. 2021-02-08. PMID:32853020. |
in addition, mtt, flow cytometry, immunofluorescence staining, and western blotting were performed to evaluate the proliferation, apoptosis, and autophagy of liver cancer cells. |
2021-02-08 |
2023-08-13 |
human |
| Yinhe Tang, Naijing Ma, Hao Luo, Shizuan Chen, Fuxiang Y. Downregulated long non-coding RNA LINC01093 in liver fibrosis promotes hepatocyte apoptosis via increasing ubiquitination of SIRT1. Journal of biochemistry. vol 167. issue 5. 2021-02-05. PMID:32044992. |
the effect of linc01093 on cell apoptosis and viability of hepatocytes were investigated after linc01093 overexpression or knockdown using flow cytometry and mtt [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] assay. |
2021-02-05 |
2023-08-13 |
mouse |