| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wanwan Zhu, Chunmei Lv, Jiao Wang, Qiang Gao, Hui Zhu, Haixia We. Patuletin induces apoptosis of human breast cancer SK-BR-3 cell line via inhibiting fatty acid synthase gene expression and activity. Oncology letters. vol 14. issue 6. 2020-09-30. PMID:29344187. |
mtt assays and flow cytometry were used to measure cell growth and cell apoptosis, respectively, following patuletin treatment. |
2020-09-30 |
2023-08-13 |
human |
| Zhiwei Shang, Haixia Feng, Lisha Cui, Weiping Wang, Hongwei F. Propofol promotes apoptosis and suppresses the HOTAIR-mediated mTOR/p70S6K signaling pathway in melanoma cells. Oncology letters. vol 15. issue 1. 2020-09-30. PMID:29375720. |
b16f10 cells were cultured with different concentrations (0-10 µm) of propofol for 24 or 48 h. proliferation and apoptosis of b16f10 cells were detected using mtt assay and flow cytometry. |
2020-09-30 |
2023-08-13 |
Not clear |
| Lingfeng Wan, Xin Yuan, Mantian Liu, Boyu Xu. miRNA-223-3p regulates NLRP3 to promote apoptosis and inhibit proliferation of hep3B cells. Experimental and therapeutic medicine. vol 15. issue 3. 2020-09-30. PMID:29467847. |
hep3b cells were then transfected with mir-223 mimics and the proliferation and apoptosis were determined by an mtt and a flow cytometric assay, respectively. |
2020-09-30 |
2023-08-13 |
Not clear |
| Xuefeng Zhang, Yun Chen, Liming Dong, Benkang Sh. Effect of selective inhibition of aquaporin 1 on chemotherapy sensitivity of J82 human bladder cancer cells. Oncology letters. vol 15. issue 3. 2020-09-30. PMID:29467903. |
reverse transcription-polymerase chain reaction was used to quantify the expression of aqp-1mrna in the cells; cell viability was analyzed with mtt assay and apoptosis was measured by flow cytometry. |
2020-09-30 |
2023-08-13 |
human |
| Yanxia Sun, Yingzhen Gu. Expression of Caspase-1 in breast cancer tissues and its effects on cell proliferation, apoptosis and invasion. Oncology letters. vol 15. issue 5. 2020-09-30. PMID:29725399. |
the mtt method detected the changes to cell proliferation, flow cytometry detected the rate of apoptosis, and a transwell assay was employed to assess invasion. |
2020-09-30 |
2023-08-13 |
human |
| Jing Chen, Jun Liang, Shihai Liu, Shanai Song, Wenxuan Guo, Fangzhen She. Differential regulation of AKT1 contributes to survival and proliferation in hepatocellular carcinoma cells by mediating Notch1 expression. Oncology letters. vol 15. issue 5. 2020-09-30. PMID:29725418. |
molecular mechanisms and the influences of different regulation the expression of akt1 on hcc cell growth, proliferation were determined by western blotting, mtt and colony formation assays, cell cycle and apoptosis were investigated by flow cytometry. |
2020-09-30 |
2023-08-13 |
Not clear |
| Sha Feng, Jue Liu, Biao Cheng, Aiping Deng, Hong Zhan. (-)-Epigallocatechin-3-gallate protects PC12 cells against corticosterone-induced neurotoxicity via the hedgehog signaling pathway. Experimental and therapeutic medicine. vol 15. issue 5. 2020-09-30. PMID:29731823. |
cell viability was assessed using an mtt assay, changes in cell morphology were observed using phase-contrast microscopy, cellular apoptosis was assessed by hoechst 33342 staining, cell proliferation was measured using a cell counting kit-8 assay, mrna levels were measured by reverse transcription-quantitative polymerase chain reaction and protein expression was assessed using western blot analysis. |
2020-09-30 |
2023-08-13 |
Not clear |
| Jing Xu, He Huang, Renjun Peng, Xiping Ding, Bing Jiang, Xianrui Yuan, Jian X. MicroRNA-30a increases the chemosensitivity of U251 glioblastoma cells to temozolomide by directly targeting beclin 1 and inhibiting autophagy. Experimental and therapeutic medicine. vol 15. issue 6. 2020-09-30. PMID:29805498. |
mtt and flow cytometry assay results showed that treatment with tmz inhibited the proliferation of u251 cells while inducing cell apoptosis in a dose-dependent manner. |
2020-09-30 |
2023-08-13 |
Not clear |
| Yaqin Chai, Huijun Xue, Yanmei Wu, Xiaomei Du, Zhuohong Zhang, Yinliang Zhang, Lili Zhang, Shuanbao Zhang, Zhiguo Zhang, Zhiwen Xu. MicroRNA-216b-3p inhibits lung adenocarcinoma cell growth via regulating PDZ binding kinase/T-LAK-cell-originated protein kinase. Experimental and therapeutic medicine. vol 15. issue 6. 2020-09-30. PMID:29805502. |
an mtt assay was applied to detect cell proliferation, and cell apoptosis was analyzed by flow cytometry. |
2020-09-30 |
2023-08-13 |
human |
| Changhe Zhang, Hong Xu, Zhenping Zhou, Ye Tian, Xiaofei Cao, Guochang Cheng, Qinghong Li. Blocking of the EGFR-STAT3 signaling pathway through afatinib treatment inhibited the intrahepatic cholangiocarcinoma. Experimental and therapeutic medicine. vol 15. issue 6. 2020-09-30. PMID:29805522. |
subsequently, the human icc cell lines jck and oz were exposed to different doses of afatinib, and then cell viability and apoptosis were determined by mtt assay and flow cytometry, respectively. |
2020-09-30 |
2023-08-13 |
human |
| Bing Zhang, Jinzhong Sun, Xiaoli Yao, Juanjuan Li, Yi Tu, Feng Yao, Shengrong Su. Knockdown of B7H6 inhibits tumor progression in triple-negative breast cancer. Oncology letters. vol 16. issue 1. 2020-09-30. PMID:29963127. |
b7h6 was knocked down using small interfering rna, and an mtt assay was performed to determine proliferation ability, flow cytometry was used to analyze apoptosis, and transwell and wound-healing assays were performed to measure migration ability. |
2020-09-30 |
2023-08-13 |
human |
| Peter Mu-Hsin Chang, Chi-Tung Cheng, Ren-Chin Wu, Yi-Hsiu Chung, Kun-Chun Chiang, Ta-Sen Yeh, Chun-Yu Liu, Ming-Han Chen, Ming-Huang Chen, Chun-Nan Ye. Nab-paclitaxel is effective against intrahepatic cholangiocarcinoma via disruption of desmoplastic stroma. Oncology letters. vol 16. issue 1. 2020-09-30. PMID:29963132. |
in the present study, mtt and annexin-v apoptosis detection kits were used to evaluate the efficacy of paclitaxel and nab-paclitaxel against human cholangiocarcinoma kku-100 and kku-213 cell lines. |
2020-09-30 |
2023-08-13 |
human |
| Aili Li, Qingqing Wang, Gaofeng He, Junfei Jin, Guojin Huan. DEP domain containing 1 suppresses apoptosis via inhibition of A20 expression, which activates the nuclear factor κB signaling pathway in HepG2 cells. Oncology letters. vol 16. issue 1. 2020-09-30. PMID:29963168. |
cell proliferation was examined using an mtt assay and apoptosis was analyzed via detection of the apoptotic marker caspase-3 using western blot analysis. |
2020-09-30 |
2023-08-13 |
Not clear |
| Liang-Bo Hu, Yin Chen, Xiao-Dong Meng, Pan Yu, Xu He, Jie L. Nucleotide Excision Repair Factor XPC Ameliorates Prognosis by Increasing the Susceptibility of Human Colorectal Cancer to Chemotherapy and Ionizing Radiation. Frontiers in oncology. vol 8. 2020-09-30. PMID:30109214. |
interestingly, mtt and apoptosis assay demonstrated that xpc gene overexpression significantly increased the susceptibility of hrc cell lines to cisplatin and x-ray radiation. |
2020-09-30 |
2023-08-13 |
human |
| Sergiu Chira, Lajos Raduly, Cornelia Braicu, Ancuta Jurj, Roxana Cojocneanu-Petric, Laura Pop, Valentina Pileczki, Calin Ionescu, Ioana Berindan-Neago. Premature senescence activation in DLD-1 colorectal cancer cells through adjuvant therapy to induce a miRNA profile modulating cellular death. Experimental and therapeutic medicine. vol 16. issue 2. 2020-09-30. PMID:30116375. |
a number of functionality assays were performed, including mtt, apoptosis and autophagy, and mitochondrial activity and senescence assays, in addition to assessing the capacity to modify the pattern of released mirna via microarray technology. |
2020-09-30 |
2023-08-13 |
Not clear |
| Maryam Fanian, Maedeh Bahmani, Mojdeh Mozafari, Samaneh Naderi, Marzieh Alizadeh Zareie, Mohammad Ali Okhovat, Jamileh Saberzadeh, Ali Dehshahri, Mohammad Ali Takhshi. The Synergistic Effects of Celecoxib and Sodium Valproate on Apoptosis and Invasiveness Behavior of Papillary Thyroid Cancer Cell Line Iranian journal of pharmaceutical research : IJPR. vol 17. issue 3. 2020-09-30. PMID:30127823. |
the effect of cx and vpa on b-cpap cells viability and apoptosis were investigated using mtt assay and annexin v/7-aad flowcytometry, respectively. |
2020-09-30 |
2023-08-13 |
Not clear |
| Shuna Yao, Yanyan Liu, Zhihua Yao, Yan Zhao, Haiying Wang, Yuanlin Xu, Jiuyang Zhang, Jing Li, Shujun Yan. MicroRNA-376a regulates cell proliferation and apoptosis by targeting forkhead box protein P2 in lymphoma. Oncology letters. vol 16. issue 3. 2020-09-30. PMID:30127911. |
the expression of mir-376a in lymphoma issue and cells was detected by reverse transcription quantitative polymerase chain reaction (rt-qpcr), the expression of forkhead box protein p2 (foxp2) was detected by rt-qpcr and western blot analysis, and the effect of mir-376a on cell proliferation and apoptosis were studied by an mtt assay and flow cytometry, respectively. |
2020-09-30 |
2023-08-13 |
Not clear |
| Zhen Lu, Aman Xu, Xiao Yuan, Kaiwei Chen, Likun Wang, Tao Gu. Anticancer effect of resibufogenin on gastric carcinoma cells through the phosphoinositide 3-kinase/protein kinase B/glycogen synthase kinase 3β signaling pathway. Oncology letters. vol 16. issue 3. 2020-09-30. PMID:30127928. |
mgc-803 cells were treated with 0, 1, 2, 4 and 8 µm resibufogenin for 12, 24 and 48 h. cell viability and apoptosis were measured using an mtt assay and annexin v staining. |
2020-09-30 |
2023-08-13 |
Not clear |
| Xiao-Wu Xu, Xiao-Min Yang, Wei-Jia Zhao, Lei Zhou, De-Chun Li, Yi-Hu Zhen. DNM1L, a key prognostic predictor for gastric adenocarcinoma, is involved in cell proliferation, invasion, and apoptosis. Oncology letters. vol 16. issue 3. 2020-09-30. PMID:30127972. |
mtt, flow cytometry, and transwell assays were used to detect the changes in cell proliferation, apoptosis, and invasion, respectively. |
2020-09-30 |
2023-08-13 |
human |
| Mengyi Hou, Zhenglan Huang, Sicheng Chen, Hao Wang, Tianyu Feng, Shujuan Yan, Yuxi Su, Guowei Zu. Synergistic antitumor effect of suberoylanilide hydroxamic acid and cisplatin in osteosarcoma cells. Oncology letters. vol 16. issue 4. 2020-09-30. PMID:30197679. |
the cytotoxicity effects of the combination of saha and cisplatin on 143b cells were analyzed by mtt assay, colony formation assay, wound healing cell migration assay, cell apoptosis assay and cell cycle analysis. |
2020-09-30 |
2023-08-13 |
Not clear |