| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Miaomiao Yu, Jinxia Li. MicroRNA-30d-5p promotes ovarian granulosa cell apoptosis by targeting Smad2. Experimental and therapeutic medicine. vol 19. issue 1. 2020-10-01. PMID:31853272. |
the levels of mir-30d-5p were detected via reverse transcription-quantitative pcr (rt-qpcr), cell proliferation was detected via an mtt assay and cell apoptosis was measured via flow cytometry. |
2020-10-01 |
2023-08-13 |
rat |
| Ming Li, Yingxin Wang, Xia Liu, Zhenduo Zhang, Liwei Wang, Yong L. miR-629 targets FOXO3 to promote cell apoptosis in gastric cancer. Experimental and therapeutic medicine. vol 19. issue 1. 2020-10-01. PMID:31853302. |
additionally, the cell proliferation and apoptosis rate were determined via an mtt assay and flow cytometry, respectively. |
2020-10-01 |
2023-08-13 |
human |
| Lili Ren, Wenju Mo, Linling Wang, Xiaojia Wan. Matrine suppresses breast cancer metastasis by targeting ITGB1 and inhibiting epithelial-to-mesenchymal transition. Experimental and therapeutic medicine. vol 19. issue 1. 2020-10-01. PMID:31853313. |
the proliferation of mda-mb-231 cells was inhibited and apoptosis was induced following treatment with mat, as determined by mtt and annexin-v-fitc/pi assays. |
2020-10-01 |
2023-08-13 |
human |
| Han Peng, Hua Yang, Xin Xiang, Shenggang L. ΜicroRNA-221 participates in cerebral ischemic stroke by modulating endothelial cell function by regulating the PTEN/PI3K/AKT pathway. Experimental and therapeutic medicine. vol 19. issue 1. 2020-10-01. PMID:31885694. |
cell viability, migration and invasion, and cell apoptosis were determined using mtt assay, transwell assay and flow cytometry respectively. |
2020-10-01 |
2023-08-13 |
human |
| Tingting Meng, Shiman Shen, Cheng Li, Xuehua Li. MicroRNA-1236-3p/translationally controlled tumor protein (TPT1) axis participates in congenital hypothyroidism progression by regulating neuronal apoptosis. Experimental and therapeutic medicine. vol 19. issue 1. 2020-10-01. PMID:31885695. |
flow cytometry and mtt assay were used to measure neuronal cell apoptosis and cell viability, whereas western blotting was applied to detect the expression of pim-3, p-bad (ser112), bad and bcl-xl, proteins associated with apoptosis. |
2020-10-01 |
2023-08-13 |
rat |
| Xinchen Zhang, Liying Zhang, Shu Wang, Dequan Wu, Weiliang Yan. Decreased functional expression of Grp78 and Grp94 inhibits proliferation and attenuates apoptosis in a human gastric cancer cell line Oncology letters. vol 9. issue 3. 2020-09-30. PMID:25663878. |
the rates of cellular proliferation and apoptosis were assayed using mtt and flow cytometry analyses, respectively. |
2020-09-30 |
2023-08-13 |
human |
| Jianjun Gu, Rong Xu, Yaxing Li, Jianhe Zhang, Shousen Wan. MicroRNA-218 modulates activities of glioma cells by targeting HMGB1. American journal of translational research. vol 8. issue 9. 2020-09-30. PMID:27725858. |
the cell proliferation, apoptosis, migration and invasion were studied using mtt, flow cytometry, transwell assay and scratch-wound assay, respectively. |
2020-09-30 |
2023-08-13 |
Not clear |
| Qifeng Luo, Shiva Basnet, Zhenling Dai, Shuping Li, Zhenyu Zhang, Haiyan G. A novel E1B55kDa-deleted oncolytic adenovirus carrying microRNA-143 exerts specific antitumor efficacy on colorectal cancer cells. American journal of translational research. vol 8. issue 9. 2020-09-30. PMID:27725862. |
mtt and cell apoptosis assays were applied to explore the biological functions of ad-zd55-mir-143 within sw480 cells. |
2020-09-30 |
2023-08-13 |
human |
| Yunfeng Yi, Xiujuan Lu, Jianming Chen, Changjie Jiao, Jing Zhong, Zhiming Song, Xiaoping Yu, Baoli Li. Downregulated miR-486-5p acts as a tumor suppressor in esophageal squamous cell carcinoma. Experimental and therapeutic medicine. vol 12. issue 5. 2020-09-30. PMID:27882172. |
the present study aimed to analyze the expression levels of mir-486-5p in escc tissues and paired normal adjacent tissues, and determine the effects of mir-486-5p on esophageal cancer cells using mtt, wound scratch and apoptosis assays. |
2020-09-30 |
2023-08-13 |
Not clear |
| Wenxian Zheng, Shuyan Han, Shantong Jiang, Lina Pang, Xiaohong Li, Xijuan Liu, Minhua Cao, Pingping L. Multiple effects of Xihuang pill aqueous extract on the Hs578T triple-negative breast cancer cell line. Biomedical reports. vol 5. issue 5. 2020-09-30. PMID:27882217. |
first, an mtt assay was used to evaluate the anti-proliferative activity of aexhp on the hs578t cell line; furthermore, the cell cycle distribution, mitochondrial membrane potential and apoptotic rate were determined by flow cytometry, and western blot analysis was used to assess the expression of apoptosis and cell cycle regulatory proteins to investigate the mechanisms of action. |
2020-09-30 |
2023-08-13 |
Not clear |
| Wei Zhan, Xin Liao, Lei Yu, Tian Tian, Xing Liu, Jing Liu, Li-Jun Cai, Xuan Xiao, Ru-Jia Xie, Qin Yan. Effects of blueberries on migration, invasion, proliferation, the cell cycle and apoptosis in hepatocellular carcinoma cells. Biomedical reports. vol 5. issue 5. 2020-09-30. PMID:27882220. |
the mtt assay was used for detecting cell proliferation, transwell assay was performed for migration and invasion evaluation, and cell cycle and apoptosis were assessed by flow cytometry. |
2020-09-30 |
2023-08-13 |
human |
| Li Li, Tianyang Xue, Wei Xu, Bin Zho. Effect of matrine combined with cisplatin on the expression of XIAP in human rhabdomyosarcoma RD cells. Oncology letters. vol 12. issue 5. 2020-09-30. PMID:27895732. |
an mtt assay and flow cytometry were applied to detect the survival and apoptotic rates, respectively, while rt-pcr was applied to detect the expression levels of x-linked inhibitor of apoptosis protein (xiap) mrna in the rd cells of each group. |
2020-09-30 |
2023-08-13 |
human |
| Bo Huang, Hongli Zhou, Siwang Wang, Xian Ping Lang, Xiaodong Wan. Effect of silencing SATB1 on proliferation, invasion and apoptosis of A549 human lung adenocarcinoma cells. Oncology letters. vol 12. issue 5. 2020-09-30. PMID:27895736. |
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt), transwell and scratch assays were used to study cell proliferation, invasion and migration activity, and the apoptosis rate was tested by flow cytometry. |
2020-09-30 |
2023-08-13 |
human |
| Thomas Gehrke, Agmal Scherzad, Stephan Hackenberg, Philipp Schendzielorz, Rudolf Hagen, Norbert Kleinsasse. Differences in tumor stroma derived from irradiated versus non-irradiated fibroblasts in a co-culture model with head and neck squamous cell carcinoma. Oncology letters. vol 12. issue 5. 2020-09-30. PMID:27900035. |
subsequently, cells were analyzed for tumor viability, apoptosis, and secretion of interleukin (il)-6 and -8 by performing an mtt assay, annexin v-propidium iodide test and enzyme-linked immunosorbent assay, respectively. |
2020-09-30 |
2023-08-13 |
human |
| Jianjun Chen, Zhenjun Wang, Sanshui Y. AIM2 regulates viability and apoptosis in human colorectal cancer cells via the PI3K/Akt pathway. OncoTargets and therapy. vol 10. 2020-09-30. PMID:28243117. |
using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay and flow cytometry, we demonstrated that expression of aim2 inhibited the viability and increased the apoptosis rate of crc cells, and cell cycle analysis suggested that aim2 blocked cell cycle transition from g1 to s phase. |
2020-09-30 |
2023-08-13 |
human |
| Daiyong Wang, Bing Wang, Ruohan Wang, Zaizhong Zhang, Youdong Lin, Guoliang Huang, Songbin Lin, Yifan Jiang, Wenyuan Wang, Lie Wang, Qiaojia Huan. High expression of EGFR predicts poor survival in patients with resected T3 stage gastric adenocarcinoma and promotes cancer cell survival. Oncology letters. vol 13. issue 5. 2020-09-30. PMID:28521408. |
annexin v apoptosis and mtt cell viability assays were performed to explore the effect of egfr on ags gastric adenocarcinoma cell survival. |
2020-09-30 |
2023-08-13 |
Not clear |
| Xinmin Guo, Shunhua Guo, Liwen Pan, Li Ruan, Yingshi Gu, Jichuang La. Anti-microRNA-21/221 and microRNA-199a transfected by ultrasound microbubbles induces the apoptosis of human hepatoma HepG2 cells. Oncology letters. vol 13. issue 5. 2020-09-30. PMID:28529584. |
to determine the effect of anti-mir-21, anti-mir-221 and mir-199a on hepg2 cells, mtt, cell cycle analysis and annexin v-pe/7-add apoptosis assays were performed. |
2020-09-30 |
2023-08-13 |
human |
| Qifeng Luo, Heying Liu, Zhenyu Zhang, Shiva Basnet, Zhenling Dai, Shuping Li, Yuxiang Wang, Bin Xu, Haiyan G. A dual-regulated oncolytic adenovirus carrying TAp63 gene exerts potent antitumor effect on colorectal cancer cells. American journal of translational research. vol 9. issue 6. 2020-09-30. PMID:28670384. |
mtt and cell apoptosis assays were applied to explore the biological functions of ad-survivin-zd55-tap63 within hct116 cells. |
2020-09-30 |
2023-08-13 |
mouse |
| Xueming Ying, Jun Chen, Xueming Huang, Peng Huang, Shaocong Ya. Effect of AXL on the epithelial-to-mesenchymal transition in non-small cell lung cancer. Experimental and therapeutic medicine. vol 14. issue 1. 2020-09-30. PMID:28673000. |
furthermore, downregulation of axl expression by rna interference was shown to inhibit cell growth by inducing the apoptosis of pc9 cells, as demonstrated by mtt and flow cytometry analyses. |
2020-09-30 |
2023-08-13 |
Not clear |
| Zhi-Ren Zhang, Ming-Xia Gao, Kai Yan. Cucurbitacin B inhibits cell proliferation and induces apoptosis in human osteosarcoma cells via modulation of the JAK2/STAT3 and MAPK pathways. Experimental and therapeutic medicine. vol 14. issue 1. 2020-09-30. PMID:28673003. |
cucurbitacin b (20-100 µm) significantly reduced cell viability (p<0.05) and induced apoptosis, as assessed by mtt and annexin v/propidium iodide staining, along with inhibiting cell migration. |
2020-09-30 |
2023-08-13 |
human |