| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yichen Jin, Ru Huang, Yanfu Xia, Chen Huang, Feng Qiu, Jinxian Pu, Xuefeng He, Xiaojun Zha. Long Noncoding RNA DNA and cell biology. vol 39. issue 7. 2020-07-20. PMID:32343913. |
mtt and tunel experiments were used to show cell viability and apoptosis, respectively. |
2020-07-20 |
2023-08-13 |
Not clear |
| Elahe Seyed Hosseini, Marziyeh Alizadeh Zarei, Sadegh Babashah, Roohollah Nakhaei Sistani, Majid Sadeghizadeh, Hamad Haddad Kashani, Javad Amini Mahabadi, Fatemeh Izadpanah, Mohhamad Ali Atlasi, Hossein Nikza. Studies on combination of oxaliplatin and dendrosomal nanocurcumin on proliferation, apoptosis induction, and long non-coding RNA expression in ovarian cancer cells. Cell biology and toxicology. vol 35. issue 3. 2020-07-16. PMID:30478652. |
the aim of this study was to determine the effects of dendrosomal nanocurcumin (dnc) and oxaliplatin (oxa) and their combination on cell death and apoptosis induction in human ovarian carcinoma cell lines analyzed by mtt assay and flow cytometry, respectively. |
2020-07-16 |
2023-08-13 |
human |
| Mai M Elkeiy, Abeer A Khamis, Mona M El-Gamal, Maha M Abo Gazia, Zeinb A Zalat, Mohammed A El-Mag. Chitosan nanoparticles from Artemia salina inhibit progression of hepatocellular carcinoma in vitro and in vivo. Environmental science and pollution research international. vol 27. issue 16. 2020-07-10. PMID:30293105. |
administration of cnps decreased hcc progression as evidenced by (1) induced hepg2 cell death as detected by mtt assay; (2) induced necrosis as indicated by acridine orange/propidium iodide (ao/pi) red staining, annexin v/7-aad positive staining (detected by flow cytometry), and upregulated expression of necrosis markers (parp1 and its downstream target, rip1 genes), but no effect on apoptosis as revealed by insignificant changes in caspase 3 activity and mrna levels of bax and aif; (3) increased intracellular ros and decreased mitochondrial membrane potential in hepg2; (4) decreased liver relative weight, serum levels of liver enzymes (alt, ast, and alp), total bilirubin, and cancer markers (afp and ggt), number and area of gst-p positive tumor nodules; and (5) reduced oxidative stress (decrease in mda levels) and increased activities of sod, cat, and gpx enzymes in rat liver. |
2020-07-10 |
2023-08-13 |
rat |
| Peng Li, Zhiwei Xiao, Jiajun Luo, Yaojun Zhang, Lizhu Li. MiR-139-5p, miR-940 and miR-193a-5p inhibit the growth of hepatocellular carcinoma by targeting SPOCK1. Journal of cellular and molecular medicine. vol 23. issue 4. 2020-07-10. PMID:30710422. |
through 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-h-tetrazolium bromide,thiazolyl blue tetrazolium bromide (mtt) and transwell assays and flow cytometry, hcc cell viability, invasion and apoptosis were determined. |
2020-07-10 |
2023-08-13 |
mouse |
| Mehran Nazarparvar-Noshadi, Jafar Ezzati Nazhad Dolatabadi, Yahya Rasoulzadeh, Yousef Mohammadian, Dariush Shanehband. Apoptosis and DNA damage induced by silica nanoparticles and formaldehyde in human lung epithelial cells. Environmental science and pollution research international. vol 27. issue 15. 2020-07-10. PMID:32198691. |
the cells were exposed to snps and fa separately and in combined form and the single and combined toxicity of snps and fa were evaluated by focusing on cellular viability, dna damage, and apoptosis via mtt, dapi staining, dna ladder, and annexin v-fitc apoptosis assays. |
2020-07-10 |
2023-08-13 |
human |
| Yan Wu, Li Xu, Jiwen Qian, Leilei Shi, Yue Su, Youfu Wang, Dawei Li, Xinyuan Zh. Methotrexate-Mn Biomaterials science. vol 8. issue 2. 2020-07-07. PMID:31777869. |
then we confirmed that the antitumor ability was mediated by mtx through mtt and cell apoptosis assay in vitro. |
2020-07-07 |
2023-08-13 |
Not clear |
| Xingzhen Zhang, Lixia Zhao, Guangxi Zhai, Jianbo Ji, Anchang Li. Multifunctional Polyethylene Glycol (PEG)-Poly (Lactic-Co-Glycolic Acid) (PLGA)-Based Nanoparticles Loading Doxorubicin and Tetrahydrocurcumin for Combined Chemoradiotherapy of Glioma. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2020-06-26. PMID:31856143. |
the in vitro mtt, apoptosis, and clone formation assays were performed to detect the proliferation and radiosensitivity of cells with various treatments. |
2020-06-26 |
2023-08-13 |
mouse |
| Xingzhen Zhang, Lixia Zhao, Guangxi Zhai, Jianbo Ji, Anchang Li. Multifunctional Polyethylene Glycol (PEG)-Poly (Lactic-Co-Glycolic Acid) (PLGA)-Based Nanoparticles Loading Doxorubicin and Tetrahydrocurcumin for Combined Chemoradiotherapy of Glioma. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2020-06-26. PMID:31856143. |
mtt, apoptosis, and clone formation assays revealed the enhanced anti-cancer activity and favorable radiosensitizing effect of tf-nps-dox-thc. |
2020-06-26 |
2023-08-13 |
mouse |
| Nupoor Prasad, Jiten R Sharma, Umesh C S Yada. Induction of growth cessation by acacetin via β-catenin pathway and apoptosis by apoptosis inducing factor activation in colorectal carcinoma cells. Molecular biology reports. vol 47. issue 2. 2020-06-23. PMID:31734898. |
cell survival was examined by trypan-blue exclusion and mtt assays, cell cycle analysis by facs, apoptosis was assessed using annexin v fitc assay and nuclear condensation by hoechst staining, ros level by dcfda and mitosox, and protein expression level by western blotting. |
2020-06-23 |
2023-08-13 |
Not clear |
| Kian Aghaabbasi, Nahid Askari, Hassan Hassani Kumleh, Masoud Torkzadeh-Mahani, Abdullah Ramzani-Ghar. The Blepharis persica seed hydroalcoholic extract synergistically enhances the apoptotic effect of doxorubicin in human colon cancer and gastric cancer cells. Molecular biology reports. vol 47. issue 2. 2020-06-23. PMID:31848915. |
the cytotoxicity was measured using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (mtt) assay while the apoptosis induction was monitored using flowcytometry by annexin-v fitc/pi double-staining. |
2020-06-23 |
2023-08-13 |
human |
| Qian Ding, Qing Wang, Yi Ren, Hong Qian Zhu, ZhuYun Huan. MicroRNA-126 attenuates cell apoptosis by targeting TRAF7 in acute myeloid leukemia cells. Biochemistry and cell biology = Biochimie et biologie cellulaire. vol 96. issue 6. 2020-06-22. PMID:29940130. |
then, we uncovered the effect of mirna-126 on aml cell proliferation and apoptosis by mtt assay and flow cytometric analysis, respectively. |
2020-06-22 |
2023-08-13 |
Not clear |
| Bin Zhou, Hong-Yun Liu, Bao-Lian Zhu, Ai-Xia Yu. MicroRNA-141 protects PC12 cells against hypoxia/reoxygenation-induced injury via regulating Keap1-Nrf2 signaling pathway. Journal of bioenergetics and biomembranes. vol 51. issue 4. 2020-06-22. PMID:31273531. |
the expression of mir-141 and keap1/nrf2 pathway was measured by qrt-pcr and western blotting, cell viability evaluated by mtt assay while cell apoptosis tested by flow cytometry. |
2020-06-22 |
2023-08-13 |
Not clear |
| Donatella Vizza, Simona Lupinacci, Giuseppina Toteda, Francesco Puoci, Parisi Ortensia I, Anna De Bartolo, Danilo Lofaro, Luca Scrivano, Renzo Bonofiglio, Antonella La Russa, Martina Bonofiglio, Anna Perr. An Olive Leaf Extract Rich in Polyphenols Promotes Apoptosis in Cervical Cancer Cells by Upregulating p21 Nutrition and cancer. vol 71. issue 2. 2020-06-12. PMID:30661406. |
mtt assay results showed a reduction of hela cells viability ole-induced, concomitantly with a gene and protein down-regulation of cyclin-d1 and an up-regulation of p21, triggering intrinsic apoptosis. |
2020-06-12 |
2023-08-13 |
human |
| Chang-Yu Liang, Zhi-Guang Huang, Zhong-Qing Tang, Xiao-Ling Xiao, Jing-Jing Zeng, Zhen-Bo Fen. FOXO1 and hsa-microRNA-204-5p affect the biologic behavior of MDA-MB-231 breast cancer cells. International journal of clinical and experimental pathology. vol 13. issue 5. 2020-06-11. PMID:32509089. |
mir-204 targeted the 3' untranslated region of foxo1 and reduced foxo1 expression in mir-204-transfected cells, resulting in cell growth amplification but inhibition of cell migration and apoptosis, which were assessed using the mtt method, wound healing assays, and flow cytometry, respectively. |
2020-06-11 |
2023-08-13 |
Not clear |
| Citong Zhang, Wei Wei, Minghan Chi, Yao Wan, Xue Li, Manlin Qi, Yanmin Zho. FOXO1 Mediates Advanced Glycation End Products Induced Mouse Osteocyte-Like MLO-Y4 Cell Apoptosis and Dysfunctions. Journal of diabetes research. vol 2019. 2020-06-09. PMID:31886284. |
mtt assay and annexin v assay showed that age significantly induce mlo-y4 cell apoptosis. |
2020-06-09 |
2023-08-13 |
mouse |
| Yi Qian, Yaoshu Teng, Yuandong Li, Xiaojiang Lin, Ming Guan, Yong Li, Xiaolin Cao, Yueqiu Ga. MiR-143-3p suppresses the progression of nasal squamous cell carcinoma by targeting Bcl-2 and IGF1R. Biochemical and biophysical research communications. vol 518. issue 3. 2020-06-08. PMID:31443963. |
then, we investigated the role of mir-143-3p in human nscc cell proliferation, apoptosis, cycle and migration by using mtt, flow cytometry and transwell assays. |
2020-06-08 |
2023-08-13 |
human |
| Meisi Yan, Jinsong Wang, Yanlv Ren, Lin Li, Weidan He, Ying Zhang, Tong Liu, Zhigao L. Over-expression of FSIP1 promotes breast cancer progression and confers resistance to docetaxel via MRP1 stabilization. Cell death & disease. vol 10. issue 3. 2020-06-05. PMID:30814489. |
we performed mtt, caspase-glo 3/7 assay, annexin v staining, wound healing and trans-well assays to evaluate cellular apoptosis, proliferation, migration and invasion in fsip1 knockout and wild-type breast cancer cell lines. |
2020-06-05 |
2023-08-13 |
mouse |
| Jinping Yang, Lei Yuan, Ying Wen, Haiyan Zhou, Wenhan Jiang, Dan Xu, Minling Wan. Protective Effects of Naringin in Cerebral Infarction and Its Molecular Mechanism. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2020-06-05. PMID:31901198. |
cell apoptosis and cell viability was determined using flow cytometry and mtt assay. |
2020-06-05 |
2023-08-13 |
rat |
| Yu-Fei Chi, Jing-Jing Qin, Zhi Li, Qin Ge, Wei-Hui Zen. Enhanced anti-tumor efficacy of 5-aminolevulinic acid-gold nanoparticles-mediated photodynamic therapy in cutaneous squamous cell carcinoma cells. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 53. issue 5. 2020-06-04. PMID:32348428. |
cell viability, apoptosis, invasion, and migration were determined by mtt assay, flow cytometry, transwell invasion assay, and migration assay, respectively. |
2020-06-04 |
2023-08-13 |
Not clear |
| Yi Han, Shaofei Zhou, Xiaoyan Wang, Enqiang Mao, Liang Huan. SNHG14 stimulates cell autophagy to facilitate cisplatin resistance of colorectal cancer by regulating miR-186/ATG14 axis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 121. 2020-06-03. PMID:31704614. |
mtt and tunel assays were used to detect cell proliferation and apoptosis rate. |
2020-06-03 |
2023-08-13 |
Not clear |