| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wenjuan Wei, Jun Peng, Ting She. Rosuvastatin Alleviates Ischemia/Reperfusion Injury in Cardiomyocytes by Downregulating Hsa-miR-24-3p to Target Upregulated Uncoupling Protein 2. Cellular reprogramming. vol 21. issue 2. 2020-03-20. PMID:30835496. |
the expression of ucp2, cell viability, ldh level, and apoptosis level affected by downregulated hsa-mir-24-3p were assessed using qrt-pcr, western blotting, mtt, the ldh kit, and flow cytometry. |
2020-03-20 |
2023-08-13 |
Not clear |
| Qi Chen, Yu Liu, Xueyan Ding, Qinfeng Li, Fuyu Qiu, Meihui Wang, Zhida Shen, Hao Zheng, Guosheng F. Bone marrow mesenchymal stem cell-secreted exosomes carrying microRNA-125b protect against myocardial ischemia reperfusion injury via targeting SIRT7. Molecular and cellular biochemistry. vol 465. issue 1-2. 2020-03-19. PMID:31858380. |
mtt assay and flow cytometry were used to detect the viability and apoptosis of i/r myocardium cells, respectively. |
2020-03-19 |
2023-08-13 |
rat |
| Esmail Nourmohammadi, Hoda Khoshdel-Sarkarizi, Reza Nedaeinia, Hamid Reza Sadeghnia, Leila Hasanzadeh, Majid Darroudi, Reza Kazemi Oskue. Evaluation of anticancer effects of cerium oxide nanoparticles on mouse fibrosarcoma cell line. Journal of cellular physiology. vol 234. issue 4. 2020-03-18. PMID:30187476. |
toxicity assessment results show that nanoceria increases ros levels and induced apoptosis in a dose-dependent manner in cancer cells (wehi164), whereas low levels of toxicity were observed in normal cells (l929), even at the concentrations above 250 µg/ml in mtt assay. |
2020-03-18 |
2023-08-13 |
mouse |
| Saniyya Khan, Imrana Nasee. A comparative insight into the oxidative damage and cell death potential of photoilluminated aminophylline - riboflavin system in normal and cancer lung cells of swiss albino mice. Toxicology in vitro : an international journal published in association with BIBRA. vol 61. 2020-03-18. PMID:31526835. |
the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay showed decreased cell viability, confirming cytotoxic action whereas fluorescence and electron microscopic evaluation confirmed apoptosis. |
2020-03-18 |
2023-08-13 |
mouse |
| Houlin Bai, Aihua Liang, Yuejun F. Ac154 carried out anti-apoptotic role during AcMNPV infection process in the host insect cells. Molecular and cellular biochemistry. vol 463. issue 1-2. 2020-03-18. PMID:31602540. |
mtt assay showed that ac154 promoted the proliferation and inhibited apoptosis of sf9 cells. |
2020-03-18 |
2023-08-13 |
Not clear |
| Ya Liu, Xiaocui He, Yuli Chen, Dan Ca. Long non-coding RNA LINC00504 regulates the Warburg effect in ovarian cancer through inhibition of miR-1244. Molecular and cellular biochemistry. vol 464. issue 1-2. 2020-03-18. PMID:31691157. |
the oc cell proliferation, and apoptosis were evaluated by mtt assay, colony-formation assay, caspase-3 activity assay, and nucleosome elisa assay, respectively. |
2020-03-18 |
2023-08-13 |
human |
| Hong-Cheng Fang, Bao-Quan Wu, Yun-Ling Hao, Ying Luo, Hong-Lei Zhao, Wen-Ying Zhang, Zhi-Ling Zhang, Jin-Jie Liang, Wei Liu, Xie-Hui Che. KRT1 gene silencing ameliorates myocardial ischemia-reperfusion injury via the activation of the Notch signaling pathway in mouse models. Journal of cellular physiology. vol 234. issue 4. 2020-03-16. PMID:30191968. |
the mtt assay was applied for cell proliferation and flow cytometry was used for cell apoptosis. |
2020-03-16 |
2023-08-13 |
mouse |
| Benny Weiss-Steider, Yolanda Córdova, Itzen Aguiñiga-Sánchez, Edgar Ledesma-Martínez, Vanihamin Domínguez-Meléndez, Edelmiro Santiago-Osori. El Sodium caseinate and alfa-casein inhibit proliferation of the mouse myeloid cell line 32D clone 3 (32Dcl3) via TNF-α Biomedica : revista del Instituto Nacional de Salud. vol 39. issue 2. 2020-03-16. PMID:31529816. |
we assessed cell viability by mtt, induction to apoptosis by flow cytometry, and tnf-alpha synthesis by elisa. |
2020-03-16 |
2023-08-13 |
mouse |
| Attila Biro, Arnold Markovich, Judit Rita Homoki, Erzsébet Szőllősi, Csaba Hegedűs, Szabolcs Tarapcsák, János Lukács, László Stündl, Judit Remenyi. Anthocyanin-Rich Sour Cherry Extract Attenuates the Lipopolysaccharide-Induced Endothelial Inflammatory Response. Molecules (Basel, Switzerland). vol 24. issue 19. 2020-03-16. PMID:31546579. |
the optimal concentration range of sour cherry extract was selected based on mtt, apoptosis, and necrosis assays. |
2020-03-16 |
2023-08-13 |
human |
| Mohammed A Almalki, Ashraf Y Z Khalif. Silver nanoparticles synthesis from Bacillus sp KFU36 and its anticancer effect in breast cancer MCF-7 cells via induction of apoptotic mechanism. Journal of photochemistry and photobiology. B, Biology. vol 204. 2020-03-11. PMID:31982671. |
the agnps were investigated for their potential anticancer effects on the cell viability, migration and apoptosis using mtt and wound-healing assays, and flow cytometry, respectively. |
2020-03-11 |
2023-08-13 |
Not clear |
| Mei-Ling Cao, Bin-Lu Zhu, Yuan-Yuan Sun, Guang-Rong Qiu, Wei-Neng Fu, Hong-Kun Jian. MicroRNA-144 Regulates Cardiomyocyte Proliferation and Apoptosis by Targeting TBX1 through the JAK2/STAT1 Pathway. Cytogenetic and genome research. vol 159. issue 4. 2020-03-11. PMID:31982878. |
cell proliferation was detected by mtt and clone formation assay and cell cycle and apoptosis by flow cytometry. |
2020-03-11 |
2023-08-13 |
Not clear |
| Peiyu Xie, Fukuko Horio, Isao Fujii, Jien Zhao, Makoto Shinohara, Makoto Matsukur. A novel polysaccharide derived from algae extract inhibits cancer progression via JNK, not via the p38 MAPK signaling pathway. International journal of oncology. vol 52. issue 5. 2020-03-06. PMID:29512724. |
mtt assay, nuclear staining and fluorescence activated cell sorting analysis demonstrated that the novel polysaccharide reduced the viability of mcf-7 cells by inducing cell apoptosis and arresting the cells at g2/m phase. |
2020-03-06 |
2023-08-13 |
human |
| Umesh Goyal, Malancha T. p53-NF-κB Crosstalk in Febrile Temperature-Treated Human Umbilical Cord-Derived Mesenchymal Stem Cells. Stem cells and development. vol 28. issue 1. 2020-03-05. PMID:30319075. |
wj-mscs adopted a flattened morphology at 40°c, and our data from proliferation kinetics study using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) and apoptosis assays showed that wj-mscs had reduced proliferation and viability at 40°c compared with control cultures. |
2020-03-05 |
2023-08-13 |
human |
| Shelian Lu, Qunyuan X. MicroRNA-23a inhibits melanoma cell proliferation, migration, and invasion in mice through a negative feedback regulation of sdcbp and the MAPK/ERK signaling pathway. IUBMB life. vol 71. issue 5. 2020-03-04. PMID:30589231. |
mtt assay, scratch test, transwell assay, and flow cytometry were performed to evaluate cell viability, invasion, metastasis, and apoptosis in vitro, respectively. |
2020-03-04 |
2023-08-13 |
mouse |
| Sarah D'Alessandro, Yolanda Corbett, Silvia Parapini, Federica Perego, Loredana Cavicchini, Lucia Signorini, Serena Delbue, Carla Perego, Pasquale Ferrante, Donatella Taramelli, Nicoletta Basilic. Malaria pigment accelerates MTT - formazan exocytosis in human endothelial cells. Parasitology. vol 146. issue 3. 2020-03-03. PMID:30269694. |
moreover, haemozoin did not induce apoptosis or cell cycle arrest nor decreased the number of live cells, suggesting that cells viability itself was not affected and that the inhibition of mtt reduction was only apparent and probably due to accelerated mtt-formazan exocytosis. |
2020-03-03 |
2023-08-13 |
human |
| Manal Abdel-Fattah, Hesham Saeed, Lamiaa El-Shennawy, Manal Shalaby, Amira Embaby, Farid Ataya, Hoda Mahmoud, Ahmed Hussei. The Arabian camel, Camelus dromedarius interferon epsilon: Functional expression, in vitro refolding, purification and cytotoxicity on breast cancer cell lines. PloS one. vol 14. issue 9. 2020-03-03. PMID:31490936. |
in both cell lines, ifnε inhibited cell survival in a dose dependent manner as observed by mtt assay, morphological changes and apoptosis assay. |
2020-03-03 |
2023-08-13 |
human |
| Lina Yao, Weifeng Shi, Jianwen G. Micro-RNA 205-5p is Involved in the Progression of Gastric Cancer and Targets Phosphatase and Tensin Homolog (PTEN) in SGC-7901 Human Gastric Cancer Cells. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2020-03-02. PMID:31444971. |
quantitative reverse transcription polymerase chain reaction (qrt-pcr) measured mir-205-5p expression, cell proliferation was measured by mtt assay, cell apoptosis by flow cytometry, transwell and wound healing assays measured cell migration, and transmission electron microscopy (tem) showed ultrastructural changes in sgc-7901 cells. |
2020-03-02 |
2023-08-13 |
human |
| Zhigang Liu, Wenhe Zhu, Xiangyu Kong, Xi Chen, Xinyi Sun, Wei Zhang, Ruowen Zhan. Tanshinone IIA inhibits glucose metabolism leading to apoptosis in cervical cancer. Oncology reports. vol 42. issue 5. 2020-02-27. PMID:31485631. |
cell viability was measured by mtt assay, apoptosis was determined using flow cytometry and glucose uptake, lactate production, and adenosine triphosphate content were measured to assess glucose metabolism. |
2020-02-27 |
2023-08-13 |
mouse |
| Akram Mirzaei, Saeed Mohammadi, Seyed H Ghaffari, Mohsen Nikbakht, Davood Bashash, Kamran Alimoghaddam, Ardeshir Ghavamzade. Osteopontin b and c isoforms: Molecular Candidates Associated with Leukemic Stem Cell Chemoresistance in Acute MyeloidLeukemia Asian Pacific journal of cancer prevention : APJCP. vol 18. issue 6. 2020-02-25. PMID:28670893. |
to investigate associations between induction of apoptosis and opn isoform expression,two distinct aml cell lines (kg-1 as a leukemic stem cell model and u937) were treated with chemotherapy drugs,and cell viability and apoptosis were evaluated by mtt and annexin/pi assay. |
2020-02-25 |
2023-08-13 |
Not clear |
| Jianfeng Mu, Xiaodong Wang, Lihua Dong, Pengda Su. Curcumin derivative L6H4 inhibits proliferation and invasion of gastric cancer cell line BGC-823. Journal of cellular biochemistry. vol 120. issue 1. 2020-02-25. PMID:30242876. |
inhibitory effects of curcumin l6h4 on gastric cancer cells (bgc-823) were studied by the diphenyltetrazolium (mtt) assay, and cell apoptosis was detected by annexin-v/propidium iodide (pi) staining and then analyzed by flow cytometry. |
2020-02-25 |
2023-08-13 |
mouse |