| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wei Da, Jing Zhang, Rui Zhang, Jinshui Zh. Curcumin inhibits the lymphangiogenesis of gastric cancer cells by inhibiton of HMGB1/VEGF-D signaling. International journal of immunopathology and pharmacology. vol 33. 2020-01-23. PMID:31266378. |
in this study, the cytotoxic effects of curcumin were investigated in gastric cancer ags and sgc-7901 cell lines by mtt assay, and curcumin-induced morphological changes and cell apoptosis were assessed by using flow cytometry analysis and caspase-3 activity. |
2020-01-23 |
2023-08-13 |
Not clear |
| Yiqing Liu, Li Xu, Bingru Lu, Miaoqing Zhao, Li Li, Wenping Sun, Zhanjun Qiu, Bingchang Zhan. LncRNA H19/microRNA-675/PPARα axis regulates liver cell injury and energy metabolism remodelling induced by hepatitis B X protein via Akt/mTOR signalling. Molecular immunology. vol 116. 2020-01-22. PMID:31574452. |
mrna and mir-675 levels were determined by quantitative real-time pcr (qrt-pcr), protein levels were determined by western blot, cell viability was measured by the mtt assay, cell apoptosis was measured by flow cytometry, inflammatory cytokine production was determined by elisa, oxidative stress and energy metabolism were assessed by commercial kits, and the target relationship between pparα and mir-675 was confirmed by the dual-luciferase reporter assay. |
2020-01-22 |
2023-08-13 |
Not clear |
| Hongzhi Zhang, Huijuan Jiang, Huixiang Zhang, Juncai Liu, Xigang Hu, Lei Che. Anti-tumor efficacy of phellamurin in osteosarcoma cells: Involvement of the PI3K/AKT/mTOR pathway. European journal of pharmacology. vol 858. 2020-01-21. PMID:31228450. |
the effects of phe on cell viability and apoptosis were evaluated by mtt assay and flow cytometry analysis, respectively. |
2020-01-21 |
2023-08-13 |
Not clear |
| Dan Zhou, Wei Zhai, Miaomiao Zhan. Mesenchymal stem cell-derived extracellular vesicles promote apoptosis in RSC96 Schwann cells through the activation of the ERK pathway. International journal of clinical and experimental pathology. vol 11. issue 11. 2020-01-21. PMID:31949596. |
the effects of msc-evs on rsc96 cell proliferation, migration, apoptosis, and the protein levels were analyzed using the mtt and colony-forming assays, the transwell and wound healing assays, flow cytometry, and western blot, respectively. |
2020-01-21 |
2023-08-13 |
rat |
| Céléna Dubuc, Martin Savard, Veronica Bovenzi, Andrée Lessard, Jérôme Côté, Witold Neugebauer, Sameh Geha, Sylvain Chemtob, Fernand Gobei. Antitumor activity of cell-penetrant kinin B1 receptor antagonists in human triple-negative breast cancer cells. Journal of cellular physiology. vol 234. issue 3. 2020-01-20. PMID:30132865. |
we found that these compounds (ssr240612, ng67, and n2000) were more toxic to mda-mb-231 cells in comparison with low- or non-b1r expressing mcf-10a normal human mammary epithelial cells and cos-1 cells, respectively (clonogenic, mtt proliferative/cytocidal assays, and fluorescence-activated cell-sorting (facs)-based apoptosis analyses). |
2020-01-20 |
2023-08-13 |
human |
| Amin Kawarizadeh, Mohammad Tabatabaei, Saeid Hosseinzadeh, Mina Farzaneh, Maryam Pourmontaser. The effects of probiotic Bacillus coagulans on the cytotoxicity and expression of alpha toxin gene of Clostridium perfringens type A. Anaerobe. vol 59. 2020-01-20. PMID:31125604. |
flow cytometry was used to evaluate the apoptosis rate, and mtt test was used to evaluate cytotoxicity. |
2020-01-20 |
2023-08-13 |
Not clear |
| Amin Kawarizadeh, Mohammad Tabatabaei, Saeid Hosseinzadeh, Mina Farzaneh, Maryam Pourmontaser. The effects of probiotic Bacillus coagulans on the cytotoxicity and expression of alpha toxin gene of Clostridium perfringens type A. Anaerobe. vol 59. 2020-01-20. PMID:31125604. |
mtt and flow cytometry showed that both b. coagulans and its extract can significantly reduce the cytotoxicity and apoptosis rate induced by c. perfringens type a. |
2020-01-20 |
2023-08-13 |
Not clear |
| Jan J Bandolik, Alexandra Hamacher, Christian Schrenk, Robin Weishaupt, Matthias U Kassac. Class I-Histone Deacetylase (HDAC) Inhibition is Superior to pan-HDAC Inhibition in Modulating Cisplatin Potency in High Grade Serous Ovarian Cancer Cell Lines. International journal of molecular sciences. vol 20. issue 12. 2020-01-20. PMID:31234549. |
inhibition of class i hdacs by entinostat turned out superior in increasing cisplatin potency than pan-hdac inhibition in cell viability assays (mtt), apoptosis induction (subg1), and caspase 3/7 activation. |
2020-01-20 |
2023-08-13 |
Not clear |
| Tao Shan, Shuo Chen, Xi Chen, Deling Kong, Wanrun Lin, Wei Li, Jiancang Ma, Yiming Li, Xijuan Cui, Ya'an Kan. Impact of AQP-5 on the growth of colorectal cancer cells and the underlying mechanism. International journal of clinical and experimental pathology. vol 11. issue 1. 2020-01-19. PMID:31938087. |
then, cell proliferation was assessed via the mtt assay, apoptosis was assessed by annexin v-fitc/pi and tunel assays, and expression changes in bax and bcl-2 were assessed by rt-pcr and western blotting. |
2020-01-19 |
2023-08-13 |
human |
| Jia-Jing Zhu, Zong-Qiang Wang, Li-Qi Bi, Gui-Feng Li. Role of lentivirus-mediated overexpression of SOCS3 in proliferation and apoptosis of fibroblasts-like synoviocytes in Lewis rats with adjuvant-induced rheumatoid arthritis. International journal of clinical and experimental pathology. vol 11. issue 2. 2020-01-19. PMID:31938192. |
mtt assay was used for detecting cell viability, flow cytometry was used for analysis ofcell apoptosis, and enzyme-linked immunosorbent assay (elisa) was used to determine levels of inflammatory factors (interleukin [il]-2, interferon [ifn-γ] and tumor necrosis factor [tnf-α]). |
2020-01-19 |
2023-08-13 |
rat |
| Xuyan Chen, Ruifang Jin, Renpin Chen, Zhiming Huan. Complementary action of CXCL1 and CXCL8 in pathogenesis of gastric carcinoma. International journal of clinical and experimental pathology. vol 11. issue 2. 2020-01-19. PMID:31938199. |
for in vitro culture of gc cell hgc27, knockout of cxcl1 and cxcl8 genes for gc cell hgc27 was performed through rna interference, proliferation of hgc27 cells was tested by mtt, apoptosis of hgc27 cells was tested by flow cytometry, and the influence of cxcl1 and cxcl8 on hgc27 cell migration was tested by transwell. |
2020-01-19 |
2023-08-13 |
Not clear |
| Changxuan Liu, Meiyu Lou, Yu Ding, Yin Wang, Yunfang Huang, Danni Shao, Wenli Che. Ouabain-induced apoptosis and inhibition of viability of tubulointerstitial cells by regulating NKA/pSrc/pERK/pAkt/pS6k/caspase 3 may contribute to lupus nephritis development. International journal of clinical and experimental pathology. vol 11. issue 5. 2020-01-19. PMID:31938342. |
hk-2 cells were treated by ouabain with concentration 0 nm (control), 0.1 nm, 1 nm, 10 nm, 100 nm and 1000 nm for 72 h; mtt assay was performed at 24 h, 48 h and 72 h to detect cells viability, av/pi assay was conducted at 24 h to detect the cell apoptosis. |
2020-01-19 |
2023-08-13 |
human |
| Changxuan Liu, Meiyu Lou, Yu Ding, Yin Wang, Yunfang Huang, Danni Shao, Wenli Che. Ouabain-induced apoptosis and inhibition of viability of tubulointerstitial cells by regulating NKA/pSrc/pERK/pAkt/pS6k/caspase 3 may contribute to lupus nephritis development. International journal of clinical and experimental pathology. vol 11. issue 5. 2020-01-19. PMID:31938342. |
hk-2 cell viability by mtt assay was decreased while cell apoptosis by av/pi was increased at each time point after ouabain 0.1 nm, 1 nm, 10 nm, 100 nm and 1000 nm treatment compared to control group. |
2020-01-19 |
2023-08-13 |
human |
| Bin Zhou, Erlin Chen, Jiahui Chen, Juan Zhang, Nannan Zhang, Zhong Che. Overexpression of proteinase inhibitor 9 is associated with poor prognosis in human hepatocellular carcinoma and with proliferation and apoptosis in HepG2 cells International journal of clinical and experimental pathology. vol 12. issue 10. 2020-01-17. PMID:31933760. |
changes in the degree of apoptosis and proliferation were determined before and after transfection with pcdna3.1-pi9 and small interfering (si)rna-pi9 using mtt analysis, colony formation assay, and flow cytometry. |
2020-01-17 |
2023-08-13 |
human |
| Yan Liu, Huanhuan Li, Yao Li. microRNA-378a Regulates the Reactive Oxygen Species (ROS)/Phosphatidylinositol 3-Kinases (PI3K)/AKT Signaling Pathway in Human Lens Epithelial Cells and Cataract. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2020-01-16. PMID:31178586. |
the mtt and tunel assay measured cell growth and apoptosis. |
2020-01-16 |
2023-08-13 |
human |
| Tan Guiying, Li Yue, Xiong Chao, Yu Jinhai, Xu Qihu. Antitumor Effects of 8-Deoxylactucin in RB355 Human Retinoblastoma Cells Are Mediated via Apoptosis Induction, Reactive Oxygen Species Production, and Cell Cycle Arrest. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2020-01-16. PMID:31219101. |
material and methods cell viability was assessed by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay, and apoptosis was assessed by dapi staining and annexin v/propidium iodide (pi) assay. |
2020-01-16 |
2023-08-13 |
human |
| Yong Liu, Yaqing Chen, Lili Tan, Hongmei Zhao, Nuan Xia. Linc00299/miR-490-3p/AURKA axis regulates cell growth and migration in atherosclerosis. Heart and vessels. vol 34. issue 8. 2020-01-15. PMID:30734057. |
the proliferation, apoptosis and migration were detected using mtt assay, annexin v/pi staining and transwell system, respectively. |
2020-01-15 |
2023-08-13 |
Not clear |
| Dongyu Xie, Ping Zhou, Lin Liu, Wenjing Jiang, Haina Xie, Liang Zhang, Donghao Xi. Protective Effect of Astragaloside IV on Hepatic Injury Induced by Iron Overload. BioMed research international. vol 2019. 2020-01-15. PMID:31428632. |
mtt assay and annexin/pi double staining were used to measure cell viability and apoptosis. |
2020-01-15 |
2023-08-13 |
human |
| Lang-Mei Deng, Tan Tan, Tian-Yi Zhang, Xue-Fei Xiao, Huan G. miR‑1 reverses multidrug resistance in gastric cancer cells via downregulation of sorcin through promoting the accumulation of intracellular drugs and apoptosis of cells. International journal of oncology. vol 55. issue 2. 2020-01-13. PMID:31268161. |
the effect of mir‑1 on the half maximal inhibitory concentration (ic50), cell apoptosis rates and drug accumulation was uncovered by mtt assay and flow cytometric analysis. |
2020-01-13 |
2023-08-13 |
Not clear |
| Laibo Zhang, Zhoubin Tian, Wei Li, Xianquan Wang, Zhentao Man, Shui Su. Inhibitory effect of quercetin on titanium particle-induced endoplasmic reticulum stress (ERS)-related apoptosis and Bioscience reports. vol 37. issue 4. 2020-01-09. PMID:28760844. |
in this study, raw264.7 cells were pretreated with different concentrations (40, 80, and 160 μmol/l) of que for 30 min and then treated with ti particle (5 mg/ml) for 24 h. cell viability and apoptosis were determined using mtt assay and annexin v-fitc apoptosis detection kit, respectively. |
2020-01-09 |
2023-08-13 |
mouse |