| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Minghua Zhu, Yinfang Jiang, Hao Wu, Wei Shi, Guirong Lu, Degang Cong, Keyuan Liu, Shaohui Song, Jianming Re. Gambogic Acid Shows Anti-Proliferative Effects on Non-Small Cell Lung Cancer (NSCLC) Cells by Activating Reactive Oxygen Species (ROS)-Induced Endoplasmic Reticulum (ER) Stress-Mediated Apoptosis. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2019-12-16. PMID:31138775. |
cell apoptosis was evaluated by mtt (methyl thiazolyl tetrazolium) assay. |
2019-12-16 |
2023-08-13 |
Not clear |
| Hui Zhu, Xinyue Qi, Yuehe Liu, Wei Liao, Xiangshui Sun, Yuping Tan. The role and underlying mechanisms of microRNA‑214 in Legg‑Calvé‑Perthes disease. Molecular medicine reports. vol 20. issue 1. 2019-12-16. PMID:31180556. |
a luciferase reporter assay was conducted to investigate the association between mir‑214 and bax, while cell viability was determined via an mtt assay, and flow cytometry was performed to investigate cell apoptosis. |
2019-12-16 |
2023-08-13 |
Not clear |
| Jianqiang Zhang, Jing Wang, Xinan Wu, Yuhui We. Ginsenoside Rb1 inhibits proliferation and promotes apoptosis by regulating HMGB1 in uterine fibroid cells. Artificial cells, nanomedicine, and biotechnology. vol 47. issue 1. 2019-12-16. PMID:31313594. |
to study the effects of ginsenoside rb1 and the molecular mechanisms on proliferation and apoptosis of uterine fibroid cells, rb1 + pc dna3.1, rb1 + pc dna3.1-hmgb1, si-nc or si-hmgb1 was transfected into uterine fibroid cells by liposome method; the inhibitory rate and proliferation of human uterine fibroid cells were detected by mtt assay; apoptosis of uterine fibroid cells was detected by flow cytometry assay; hmgb1 protein expression in uterine fibroid cells was detected by western blot assay. |
2019-12-16 |
2023-08-13 |
human |
| Hui Lv, Jie Li, Yu-Qin Ch. MicroRNA-150 contributes to ischemic stroke through its effect on cerebral cortical neuron survival and function by inhibiting ERK1/2 axis via Mal. Journal of cellular physiology. vol 234. issue 2. 2019-12-10. PMID:30144062. |
besides, cell growth and apoptosis of ccns were detected by means of mtt assay and flow cytometry analyses. |
2019-12-10 |
2023-08-13 |
rat |
| Rui Zhang, Zhi Chen, Shu-Sheng Wu, Jun Xu, Ling-Chun Kong, Pei We. Celastrol Enhances the Anti-Liver Cancer Activity of Sorafenib. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2019-12-09. PMID:31152143. |
after combined treatment with celastrol and sorafenib, the survival rate of tumor cells was determined by mtt and clonogenic assays, and the apoptosis rate was also determined by flow cytometry. |
2019-12-09 |
2023-08-13 |
mouse |
| Behrooz Johari, Zoleykha Asadi, Elham Rismani, Faezeh Maghsood, Zahra Sheikh Rezaei, Sima Farahani, Hamid Madanchi, Mehdi Kadiva. Inhibition of transcription factor T-cell factor 3 (TCF3) using the oligodeoxynucleotide strategy increases embryonic stem cell stemness: possible application in regenerative medicine. Cell biology international. vol 43. issue 8. 2019-12-03. PMID:31033094. |
self-renewal and pluripotency of mescs were analyzed by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (mtt), cell cycle and apoptosis, alkaline phosphatase (alp), embryoid body (eb) formation, and real-time assays. |
2019-12-03 |
2023-08-13 |
mouse |
| Liqiang Zhong, Sihao Yang, Yuming Jia, Kaijian Le. Inhibition of cyclin-dependent kinase 7 suppresses human hepatocellular carcinoma by inducing apoptosis. Journal of cellular biochemistry. vol 119. issue 12. 2019-12-02. PMID:30145799. |
cell growth and apoptosis were assessed via 3-(4,5-dimethylthiazolyl-2)-2, 5-diphenyltetrazolium bromide (mtt) assay and flow cytometry analysis, respectively. |
2019-12-02 |
2023-08-13 |
mouse |
| Liqiang Zhong, Sihao Yang, Yuming Jia, Kaijian Le. Inhibition of cyclin-dependent kinase 7 suppresses human hepatocellular carcinoma by inducing apoptosis. Journal of cellular biochemistry. vol 119. issue 12. 2019-12-02. PMID:30145799. |
mtt assay and flow cytometry analysis showed that thz1 inhibited hcc cell proliferation and induced apoptosis, respectively. |
2019-12-02 |
2023-08-13 |
mouse |
| Deniz Mortazavi, Mohammadreza Sharif. Antiproliferative effect of upregulation of hsa-let-7c-5p in human acute erythroleukemia cells. Cytotechnology. vol 70. issue 6. 2019-12-01. PMID:30073438. |
qrt-pcr, mtt assay, annexin-v, and propidium iodide staining at different time points after mirna mimic transfection were accomplished to assess the expression level of hsa-let-7c-5p, cell viability, apoptosis and late apoptosis. |
2019-12-01 |
2023-08-13 |
human |
| Mengran Ke, Qiqi Tang, Ziang Pan, Yongqiang Yin, Lizhi Zhang, Ke We. Sphingosine-1-phosphate attenuates hypoxia/reoxygenation-induced cardiomyocyte injury via a mitochondrial pathway. Biochemical and biophysical research communications. vol 510. issue 1. 2019-11-29. PMID:30661785. |
cell viability was determined by the mtt assay, and apoptosis was evaluated by annexin v-fitc/pi staining. |
2019-11-29 |
2023-08-13 |
Not clear |
| Xiaoxia Tan, Lihua Jiang, Xia Wu, Wen Feng, Qingfang Li. MicroRNA-625 inhibits the progression of non‑small cell lung cancer by directly targeting HOXB5 and deactivating the Wnt/β-catenin pathway. International journal of molecular medicine. vol 44. issue 1. 2019-11-27. PMID:31115501. |
the effects of mir‑625 overexpression on nsclc cell proliferation, apoptosis, migration and invasion in vitro were assessed using an mtt assay, flow cytometry, and cell migration and invasion assays, respectively. |
2019-11-27 |
2023-08-13 |
human |
| Zhigang Nie, Shuang Deng, Lei Zhang, Sen Chen, Qiang Lu, Hao Pen. Crocin protects against dexamethasone‑induced osteoblast apoptosis by inhibiting the ROS/Ca2+‑mediated mitochondrial pathway. Molecular medicine reports. vol 20. issue 1. 2019-11-26. PMID:31115574. |
mtt and annexin v‑fitc/pi flow cytometry assays were performed to evaluate the viability and apoptosis of cells, respectively. |
2019-11-26 |
2023-08-13 |
Not clear |
| Amir Ghanbari, Zeinab Cheraghzadeh, Reza Mahmoudi, Kazem Zibara, Ebrahim Hossein. GLI inhibitors overcome Erlotinib resistance in human pancreatic cancer cells by modulating E-cadherin. Journal of chemotherapy (Florence, Italy). vol 31. issue 3. 2019-11-25. PMID:30983542. |
mtt and apoptosis assays were used to evaluate the synergistic effects for the combination treatment of each gli inhibitor with etb. |
2019-11-25 |
2023-08-13 |
human |
| Shui-Ping Tu, Jie Zhong, Ji-Hong Tan, Xiao-Hua Jiang, Min-Min Qiao, Yu-Xin Wu, Shi-Hu Jian. Induction of apoptosis by arsenic trioxide and hydroxy camptothecin in gastriccancer cells in vitro. World journal of gastroenterology. vol 6. issue 4. 2019-11-20. PMID:11819642. |
aim:to study the effects of arsenic trioxide and hcpt on dif ferent degrees of differentiated gastric cancer cells (sgc-7901, mkn-45, mkn-28) with respect to both cytotoxicity and induction of apoptosis in vitro.methods:the cytotoxicity of as(2)o(3) and hcpt on gastric cancer cells was det ermined by mtt assay.morphologic changes of apoptosis of gastric cancer cells were observed by light microscopy and transmission electron microscopy.apoptosis and cell cycle changes of gastric cancer cells induced by hcpt and as(2)o(3) we re investigated by tunel method and flow cytometry.results:as(2)o(3) and hcpt had remarkable cytotoxic effects on different degrees of differentiated gastric cancer cells. |
2019-11-20 |
2023-08-12 |
Not clear |
| Qi-Wei Zhai, Hong-Bin Ji, Zhong-Cheng Zheng, Lan-Ying Sun, Xin-Yuan Li. A Novel Type of Apoptosis Induced by Cadmium in BA/F3beta Cells. Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica. vol 32. issue 1. 2019-11-20. PMID:12110919. |
mtt assay, hochest 33258 staining, and transmission electron microscopy analysis were used to detect the apoptosis, however, neither dna fragmentation nor up-regulation of reactive oxygen species were observed in this type of apoptosis. |
2019-11-20 |
2023-08-12 |
Not clear |
| Y Ren, L Wu, X Li, W Li, Y Yang, M Zhan. FBXL10 contributes to the progression of nasopharyngeal carcinoma via involving in PI3K/mTOR pathway. Neoplasma. vol 62. issue 6. 2019-11-20. PMID:26458315. |
besides, mtt assay and flow cytometry were respectively used to explore cell proliferation and apoptosis in vitro. |
2019-11-20 |
2023-08-13 |
human |
| H Qu, M Zhu, Y Tao, Y Zha. Suppression of peripheral myelin protein 22 (PMP22) expression by miR29 inhibits the progression of lung cancer. Neoplasma. vol 62. issue 6. 2019-11-20. PMID:26458320. |
then mtt, matrigel transwell assay and flow cytometry were respectively used to explore the proliferation, invasion and apoptosis in anip973 lung adenocarcinoma cell line in vitro. |
2019-11-20 |
2023-08-13 |
Not clear |
| Jia Huang, Ziming Li, Zhengping Ding, Qingquan Luo, Shun L. Different roles of myofibroblasts in the tumorigenesis of nonsmall cell lung cancer. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 2019-11-20. PMID:26482615. |
we found that coculture with tgfβ1-overexpressing myofibroblasts significantly decreased the nsclc cell growth in an mtt assay through proliferation suppression rather than modulation of cell apoptosis, while significantly increased the nsclc cell invasiveness in either a transwell migration assay or a scratch wound healing migration assay. |
2019-11-20 |
2023-08-13 |
human |
| Yan Hong Guo, Yong Wang, Min Xi. Low concentration of formononetin stimulates the proliferation of nasopharyngeal carcinoma cell line CNE2 by upregulating bcl-2 and p-ERK1/2 expression. Pharmaceutical biology. 2019-11-20. PMID:26916669. |
cell proliferation was measured by [3-(4,5-dimethylthiazol-2-yl)]-2,5-diphenyltetrazolium bromide (mtt) assay, while the rate of apoptosis was measured by flow cytometry. |
2019-11-20 |
2023-08-13 |
Not clear |
| Vahid Salimi, Mohammad Shabani, Mitra Nourbakhsh, Masoumeh Tavakoli-Yarak. Involvement of 15-lipoxygenase-1 in the regulation of breast cancer cell death induced by sodium butyrate. Cytotechnology. vol 68. issue 6. 2019-11-20. PMID:27173588. |
mtt assay was used to assess the cytotoxicity effect and annexin-v-fitc staining was applied for detection of apoptosis using flow cytometry. |
2019-11-20 |
2023-08-13 |
Not clear |