| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Minmin Cai, Liufang Shen. MFG-E8 Exerts Neuroprotection in Neural Stem Cells Induced by Anesthetic Sevoflurane via Regulating the PI3K/AKT Pathways. Stem cells international. vol 2022. 2022-10-24. PMID:36277041. |
the cell viability and apoptosis affected by rhmfg-e8 were tested by mtt and flow cytometry analysis, respectively. |
2022-10-24 |
2023-08-14 |
Not clear |
| Ming Zhang, Zhiling Zhang, Jie Hu, Shulan Zhou, Wenwei A. Knockdown of long noncoding RNA MIAT attenuates hypoxia-induced cardiomyocyte injury by regulating the miR-488-3p/Wnt/β-catenin pathway. Cell biology international. 2022-10-23. PMID:36273414. |
the cardiomyocyte injury was assessed via cell viability and apoptosis using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (mtt) and flow cytometry, respectively. |
2022-10-23 |
2023-08-14 |
Not clear |
| Xiangling Kong, Ruifeng Zhang, Yupeng Shen, Yinhong Bai, Kaifeng Dong, Dan Li, Yan Wan. Preparation and inhibitory effect of salicin dimethyl ether in Laryngeal cancer cells through the apoptosis activation. Acta biochimica Polonica. 2022-10-21. PMID:36269869. |
mtt assay was used for the measurement of changes in tu686 and tu212 cell proliferation while as induced apoptosis was detected by flow cytometry. |
2022-10-21 |
2023-08-14 |
Not clear |
| Tao Feng, Chunyu Song, Zhiyong Wu, Ke Zhao, Shenglan Y. Role of lncRNA MIAT/miR-361-3p/CCAR2 in prostate cancer cells. Open medicine (Warsaw, Poland). vol 17. issue 1. 2022-10-17. PMID:36245704. |
the cell viability and apoptosis were detected by mtt assay and flow cytometry analysis, respectively. |
2022-10-17 |
2023-08-14 |
Not clear |
| Yifan Yang, Jing Xu, Qingxin Su, Yiran Wu, Qizheng Li, Zongren Ma, Tao Din. Lysophosphatidic Acid Induced Apoptosis, DNA Damage, and Oxidative Stress in Spinal Cord Neurons by Upregulating LPA4/LPA6 Receptors. Mediators of inflammation. vol 2022. 2022-10-17. PMID:36248188. |
after clinical detection of lpa secretion, spinal cord neurons were treated with lpa (18 : 1); cell viability was analyzed by mtt assay, and ldh leakage was detected by ldh kit; cell apoptosis was detected by flow cytometry; ros production was measured by dcfda staining and mitosox red staining; the activation of the g |
2022-10-17 |
2023-08-14 |
Not clear |
| Jing Wen, Wei Zhang, Lixin Shi, Shi Zhou, Yan Zhou, Miao Zhang, Lijuan Luo, Jine Zho. Amiodarone-drove XBP1s aggravates endoplasmic reticulum stress and apoptosis in Hashimoto's thyroiditis through regulating LINC00842/miR-214/FASL axis. International immunopharmacology. vol 113. issue Pt A. 2022-10-17. PMID:36252485. |
moreover, mtt assay and flow cytometry analysis revealed that knockdown of xbp1s suppressed amio-induced thyroid epithelial follicular cells apoptosis. |
2022-10-17 |
2023-08-14 |
Not clear |
| Katelyn Cuttler, Dalene de Swardt, Lize Engelbrecht, Jurgen Kriel, Ruben Cloete, Soraya Bardie. Neurexin 2 p.G849D variant, implicated in Parkinson's disease, increases reactive oxygen species, and reduces cell viability and mitochondrial membrane potential in SH-SY5Y cells. Journal of neural transmission (Vienna, Austria : 1996). 2022-10-15. PMID:36242655. |
wild-type and mutant nrxn2α plasmids were transfected into sh-sy5y cells to assess the effect of the mutant on cell viability and apoptosis [(3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay; apotox-glo™ triplex assay)], mitochondrial membrane potential (mmp; mitoprobe™ jc-1 assay), mitochondrial network analysis (mitotracker |
2022-10-15 |
2023-08-14 |
human |
| Jingwen Dong, Tingting Zhong, Zhijian Xu, Haiyi Chen, Xianjun Wang, Lili Yang, Zhiyuan Lou, Yuanling Xu, Tingjun Hou, Rongzhen Xu, Weiliang Zhu, Jimin Sha. Identification of Monobenzone as a Novel Potential Anti-Acute Myeloid Leukaemia Agent That Inhibits RNR and Suppresses Tumour Growth in Mouse Xenograft Model. Cancers. vol 14. issue 19. 2022-10-14. PMID:36230632. |
mb inhibited cell proliferation (mtt ic50 = 6-18 μm) and caused dose-dependent dna synthesis inhibition, cell cycle arrest, and apoptosis in aml cells. |
2022-10-14 |
2023-08-14 |
mouse |
| Li-Chiu Yang, Yu-Chao Chang, Kun-Lin Yeh, Fu-Mei Huang, Ni-Yu Su, Yu-Hsiang Kua. Protective Effect of Rutin on Triethylene Glycol Dimethacrylate-Induced Toxicity through the Inhibition of Caspase Activation and Reactive Oxygen Species Generation in Macrophages. International journal of molecular sciences. vol 23. issue 19. 2022-10-14. PMID:36233071. |
after treatment with rutin, we assessed the cell viability and apoptosis of tegdma-induced raw264.7 macrophages using an methylthiazol tetrazolium (mtt) assay and annexin v-fitc/propidium iodide assay, respectively. |
2022-10-14 |
2023-08-14 |
Not clear |
| Tangnur Ablimit, Gulxan Tursun, Yuanyuan Zhang, Guzalnur Abduxkur, Gulgina Abdurexit, Guzalnur Abli. Inositol monophosphatase 2 promotes epithelial ovarian cancer cell proliferation and migration by regulating the AKT/mTOR signaling pathway. Experimental and therapeutic medicine. vol 24. issue 5. 2022-10-14. PMID:36237598. |
in the present study, the role of impa2 in eoc development was assessed through numerous experiments, including knockdown and mtt assays; multiparametric high-content screening; colony formation, apoptosis and transwell assays, and a xenografted mouse model. |
2022-10-14 |
2023-08-14 |
mouse |
| Hui Qin, Youxue Fu, Ying Jiang, Zhao Tian, Yongquan Zhang, Wenlan Tan, Mingkun Liang, Haicheng Wen, Gang Fan. Total Flavonoids in Premna Fulva Craib Alleviates Brain Neurological Impairment and Influences Nrf2 and HO-1 Expressions in Rats with Ischemia-Reperfusion. Cellular and molecular biology (Noisy-le-Grand, France). vol 68. issue 6. 2022-10-13. PMID:36227660. |
the influences of tfpfc treatment on the proliferative activity and apoptosis of oxygen and glucose deprivation/reoxygenation (ogd/r) neural stem cells were detected via methyl thiazolyl tetrazolium (mtt) assay and flow cytometry. |
2022-10-13 |
2023-08-14 |
rat |
| Chun-Yi Ji, Miao-Xian Yuan, Li-Jian Chen, Hong-Qiang Gao, Tian Zhang, Qiang Yi. miR‑92a represses the viability and migration of nerve cells in Hirschsprung's disease by regulating the KLF4/PI3K/AKT pathway. Acta neurobiologiae experimentalis. vol 82. issue 3. 2022-10-10. PMID:36214716. |
cell viability, migration and apoptosis were evaluated by mtt, transwell and flow cytometry assays, respectively. |
2022-10-10 |
2023-08-14 |
Not clear |
| Rongjun Xiao, Qingsong Wang, Jun Peng, Zhengtao Yu, Jikun Zhang, Ying Xi. BMSC-Derived Exosomal Egr2 Ameliorates Ischemic Stroke by Directly Upregulating SIRT6 to Suppress Notch Signaling. Molecular neurobiology. 2022-10-08. PMID:36208355. |
tube formation, mtt, tunel, and flow cytometry assays were applied to examine cell angiogenesis, viability, and apoptosis. |
2022-10-08 |
2023-08-14 |
mouse |
| Tao Chen, Guangqiang Feng, Zhisong Xing, Xingcai Ga. Circ-EIF3I facilitates proliferation, migration, and invasion of lung cancer via regulating the activity of Wnt/β-catenin pathway through the miR-1253/NOVA2 axis. Thoracic cancer. 2022-10-04. PMID:36193788. |
the proliferation, apoptosis, migration, and invasion of lc cells were determined by mtt assay, colony formation assay, flow cytometry, and transwell assay. |
2022-10-04 |
2023-08-14 |
Not clear |
| Yi Wang, Leiming Xia, Jing Lin, Li Gong, Yang Xia, Yang Xu, Liu Liu, Jian Bao, Congshu Zhang, Yuqing Chai, Hongxia L. Thioridazine combined with carboplatin results in synergistic inhibition of triple negative breast cancer by targeting cancer stem cells. Translational oncology. vol 26. 2022-10-03. PMID:36191461. |
mtt, flow cytometry, electron microscopy, immunohistochemistry and western blotting were applied to assess the cell viability, apoptosis, mitochondrial morphology and the relevant protein levels, respectively. |
2022-10-03 |
2023-08-14 |
mouse |
| Lijuan Zhao, Xiuhua Liu, Chunyan Ren, Hua Zhang, Li Ga. Silencing of LncRNA SNHG6 protects trophoblast cells through regulating miR-101-3p/OTUD3 axis in unexplained recurrent spontaneous abortion. Journal of molecular histology. 2022-09-29. PMID:36173586. |
the viability, migration, and apoptosis of trophoblast cells were measured by mtt, wound healing, and flow cytometry assays, respectively. |
2022-09-29 |
2023-08-14 |
Not clear |
| Felipe Henrique de Souza Silva, Adam Underwood, Camila Pereira Almeida, Thais Salviana Ribeiro, Elaine M Souza-Fagundes, Almir S Martins, Marcos Eliezeck, Silvia Guatimosim, Luciana O Andrade, Luisa Rezende, Hipacia Werneck Gomes, Cleida Aparecida Oliveira, Raquel Cristina Rodrigues, Isabella Terra Borges, Geovanni Dantas Cassali, Enio Ferreira, Helen Lima Del Puert. Transcription factor SOX3 upregulated pro-apoptotic genes expression in human breast cancer. Medical oncology (Northwood, London, England). vol 39. issue 12. 2022-09-29. PMID:36175695. |
breast cancer cell line mda-md-231 transfected with pef1-sox3 + and pef1-empty vector followed by cytotoxicity assay (mtt), annexin-v fitc pi for apoptosis percentage assessment by flow cytometry, qpcr for apoptotic-related gene expression, immunofluorescence, and immunohistochemistry to sox3 immunolocalization in culture cells, and paraffin-embedded invasive ductal carcinoma tissue samples. |
2022-09-29 |
2023-08-14 |
human |
| Hongxia Qiu, Meixia Liu, Xuefei Shi, Miao Ma, Jing Zhang, Hua Li. LncRNA HOTAIR inhibits the progression of fibroblast-like synoviocytes by sponging miRNA-106b-5p in rheumatoid arthritis. Autoimmunity. 2022-09-27. PMID:36164683. |
the proliferation, cell invasion and migration, and cell apoptosis of hflss in ra was detected by the 3-(4,5-dimethylthiazol)-2,5-diphenyl-tetrazolium bromide (mtt) assay, transwell assay, and flow cytometry (fcm). |
2022-09-27 |
2023-08-14 |
human |
| Sicheng Chen, Mengjun Bie, Xiaowen Wang, Mengtian Fan, Bin Chen, Qiong Shi, Yingjiu Jian. PGRN exacerbates the progression of non-small cell lung cancer via PI3K/AKT/Bcl-2 antiapoptotic signaling. Genes & diseases. vol 9. issue 6. 2022-09-26. PMID:36157487. |
the proliferation, apoptosis, migration, and invasion of nsclc cells were assessed by the mtt assay, western blot, degree of wound healing, and transwell assays. |
2022-09-26 |
2023-08-14 |
mouse |
| Qiqi Zhou, Yan Zhang, Meiqing Zhao, Xia Zhao, Hongwei Xue, Shuxin Xia. Knockdown of the long non-coding RNA CACNA1G-AS1 enhances cytotoxicity and apoptosis of human diffuse large B cell lymphoma by regulating miR-3160-5p. Experimental and therapeutic medicine. vol 24. issue 4. 2022-09-26. PMID:36160896. |
after cacna1g-as1-knockdown and mir-3160-5p-overexpression, mtt, colony formation and flow cytometry assays were conducted to assess the changes in the cytotoxicity and apoptosis of oci-ly10 and sudhl-4 cells. |
2022-09-26 |
2023-08-14 |
human |