| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tao Chen, Guangqiang Feng, Zhisong Xing, Xingcai Ga. Circ-EIF3I facilitates proliferation, migration, and invasion of lung cancer via regulating the activity of Wnt/β-catenin pathway through the miR-1253/NOVA2 axis. Thoracic cancer. 2022-10-04. PMID:36193788. |
the proliferation, apoptosis, migration, and invasion of lc cells were determined by mtt assay, colony formation assay, flow cytometry, and transwell assay. |
2022-10-04 |
2023-08-14 |
Not clear |
| Yi Wang, Leiming Xia, Jing Lin, Li Gong, Yang Xia, Yang Xu, Liu Liu, Jian Bao, Congshu Zhang, Yuqing Chai, Hongxia L. Thioridazine combined with carboplatin results in synergistic inhibition of triple negative breast cancer by targeting cancer stem cells. Translational oncology. vol 26. 2022-10-03. PMID:36191461. |
mtt, flow cytometry, electron microscopy, immunohistochemistry and western blotting were applied to assess the cell viability, apoptosis, mitochondrial morphology and the relevant protein levels, respectively. |
2022-10-03 |
2023-08-14 |
mouse |
| Lijuan Zhao, Xiuhua Liu, Chunyan Ren, Hua Zhang, Li Ga. Silencing of LncRNA SNHG6 protects trophoblast cells through regulating miR-101-3p/OTUD3 axis in unexplained recurrent spontaneous abortion. Journal of molecular histology. 2022-09-29. PMID:36173586. |
the viability, migration, and apoptosis of trophoblast cells were measured by mtt, wound healing, and flow cytometry assays, respectively. |
2022-09-29 |
2023-08-14 |
Not clear |
| Felipe Henrique de Souza Silva, Adam Underwood, Camila Pereira Almeida, Thais Salviana Ribeiro, Elaine M Souza-Fagundes, Almir S Martins, Marcos Eliezeck, Silvia Guatimosim, Luciana O Andrade, Luisa Rezende, Hipacia Werneck Gomes, Cleida Aparecida Oliveira, Raquel Cristina Rodrigues, Isabella Terra Borges, Geovanni Dantas Cassali, Enio Ferreira, Helen Lima Del Puert. Transcription factor SOX3 upregulated pro-apoptotic genes expression in human breast cancer. Medical oncology (Northwood, London, England). vol 39. issue 12. 2022-09-29. PMID:36175695. |
breast cancer cell line mda-md-231 transfected with pef1-sox3 + and pef1-empty vector followed by cytotoxicity assay (mtt), annexin-v fitc pi for apoptosis percentage assessment by flow cytometry, qpcr for apoptotic-related gene expression, immunofluorescence, and immunohistochemistry to sox3 immunolocalization in culture cells, and paraffin-embedded invasive ductal carcinoma tissue samples. |
2022-09-29 |
2023-08-14 |
human |
| Hongxia Qiu, Meixia Liu, Xuefei Shi, Miao Ma, Jing Zhang, Hua Li. LncRNA HOTAIR inhibits the progression of fibroblast-like synoviocytes by sponging miRNA-106b-5p in rheumatoid arthritis. Autoimmunity. 2022-09-27. PMID:36164683. |
the proliferation, cell invasion and migration, and cell apoptosis of hflss in ra was detected by the 3-(4,5-dimethylthiazol)-2,5-diphenyl-tetrazolium bromide (mtt) assay, transwell assay, and flow cytometry (fcm). |
2022-09-27 |
2023-08-14 |
human |
| Sicheng Chen, Mengjun Bie, Xiaowen Wang, Mengtian Fan, Bin Chen, Qiong Shi, Yingjiu Jian. PGRN exacerbates the progression of non-small cell lung cancer via PI3K/AKT/Bcl-2 antiapoptotic signaling. Genes & diseases. vol 9. issue 6. 2022-09-26. PMID:36157487. |
the proliferation, apoptosis, migration, and invasion of nsclc cells were assessed by the mtt assay, western blot, degree of wound healing, and transwell assays. |
2022-09-26 |
2023-08-14 |
mouse |
| Qiqi Zhou, Yan Zhang, Meiqing Zhao, Xia Zhao, Hongwei Xue, Shuxin Xia. Knockdown of the long non-coding RNA CACNA1G-AS1 enhances cytotoxicity and apoptosis of human diffuse large B cell lymphoma by regulating miR-3160-5p. Experimental and therapeutic medicine. vol 24. issue 4. 2022-09-26. PMID:36160896. |
after cacna1g-as1-knockdown and mir-3160-5p-overexpression, mtt, colony formation and flow cytometry assays were conducted to assess the changes in the cytotoxicity and apoptosis of oci-ly10 and sudhl-4 cells. |
2022-09-26 |
2023-08-14 |
human |
| Babak Jahangiri, Mohammad Khalaj-Kondori, Elahe Asadollahi, Leyli Purrafee Dizaj, Majid Sadeghizade. MSC-Derived Exosomes Suppress Colorectal Cancer Cell Proliferation and Metastasis via miR-100/mTOR/miR-143 Pathway. International journal of pharmaceutics. 2022-09-24. PMID:36152993. |
the flow cytometry, mtt and trypan blue assays revealed that msc-exos could efficiently suppress proliferation and induce apoptosis of the crc cells. |
2022-09-24 |
2023-08-14 |
human |
| Li-Tzu Huang, Chin-Ho Kuo, Lin Tseng, Yi-Syuan Li, Li-Hsin Cheng, Chin-Yun Cheng, Shane-Rong Sheu, Wen-Tsan Chang, Chien-Chin Chen, Hung-Chi Chen. Alpha-Mangostin Reduces Pericellular Fibronectin on Suspended Tumor Cells and Therapeutically, but Not Prophylactically, Suppresses Distant Metastasis. Life (Basel, Switzerland). vol 12. issue 9. 2022-09-23. PMID:36143411. |
immunofluorescence staining, mtt assays, flow cytometric assays, immunoblotting, and experimental metastasis mouse models were used to detect the effects of mp extracts or α-mg on perifn on stcs, tumor cell proliferation and apoptosis, the akt activity, and tumor lung metastasis. |
2022-09-23 |
2023-08-14 |
mouse |
| Mohd Farhan, Asim Rizvi, Ferasat Ali, Aamir Ahmad, Mohammad Aatif, Arshi Malik, Mir Waqas Alam, Ghazala Muteeb, Saheem Ahmad, Awal Noor, Farhan Asif Siddiqu. Pomegranate juice anthocyanidins induce cell death in human cancer cells by mobilizing intracellular copper ions and producing reactive oxygen species. Frontiers in oncology. vol 12. 2022-09-23. PMID:36147917. |
using prostate, breast and pancreatic cancer cell lines pc3, mda-mb-231, bxpc-3 and miapaca-2, we show that anthocyanidins inhibit cell proliferation (measured by mtt assay) and induce apoptosis like cell death (measured by dna/histone elisa). |
2022-09-23 |
2023-08-14 |
human |
| Amin Khoshakhlagh, Saeid Abroun, Seyed Soheil Aghaei, Mohammad Soleimani, Mohammad Reza Zolfaghar. Analysis of the A549 cell line affected by anticancer bioactive compounds of Actinomycetes isolated from saline soils. Archives of microbiology. vol 204. issue 10. 2022-09-23. PMID:36149504. |
the a549 cell line was then exposed to bacterial metabolites to find their cytotoxicity by mtt assay and their capacity to cause apoptosis by flow cytometry. |
2022-09-23 |
2023-08-14 |
Not clear |
| Reyhaneh Roshan, Shamsi Naderi, Mahdi Behdani, Reza Ahangari Cohan, Fatemeh Kazemi-Lomedash. A Novel Immunotoxin Targeting Epithelial Cell Adhesion Molecule Using Single Domain Antibody Fused to Diphtheria Toxin. Molecular biotechnology. 2022-09-21. PMID:36129635. |
the cytotoxicity and apoptosis activity of α-epcam it on epcam over-expressing (mcf7), low-expressing (hek293), and no-expressing (huvec) cells were evaluated by 3-4,5-dimethylthiazol-2-yl (mtt) assay and annexin v-fitc-pi assay as well. |
2022-09-21 |
2023-08-14 |
mouse |
| Haitao Jiang, Hailang Sun, Jian Dai, Cheng Zhang, Xiaoming Tan. GINS2 Is Downregulated in Peripheral Blood of Patients with Intervertebral Disk Degeneration and Promotes Proliferation and Migration of Nucleus Pulposus Cells. Computational and mathematical methods in medicine. vol 2022. 2022-09-12. PMID:36092790. |
moreover, the influences of gins2 on cell viability, migration, and invasion were explored by mtt, wound healing, and transwell assays, whereas cell apoptosis was determined by flow cytometry. |
2022-09-12 |
2023-08-14 |
human |
| Dazhi Gao, Xiangxian Xu, Ling Liu, Li Liu, Xiang Zhang, Xianxian Liang, Lanqi Cen, Qian Liu, Xiaoli Yuan, Zhenghong Y. Combination of Peglated-H1/HGFK1 Nanoparticles and TAE in the Treatment of Hepatocellular Carcinoma. Applied biochemistry and biotechnology. 2022-09-12. PMID:36094649. |
mtt and annexin v-fitc were used to determine the cell viability and apoptosis of hepg2, ml-1, lo2, and vx2 cells after the treatment of hgfk1. |
2022-09-12 |
2023-08-14 |
rabbit |
| Yu Ma, Yi Liu, Baotong Shu, Jianguo Yang, Liang Lv, Lixiao Zhou, Lichun Wang, Zongli Sh. CircMAP3K4 protects human lens epithelial cells from H Cell cycle (Georgetown, Tex.). 2022-09-08. PMID:36071682. |
cell viability, senescence, proliferation, and apoptosis were analyzed by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay, senescence-associated-β-galactosidase (sa-β-gal) staining, 5-ethynyl-20-deoxyuridine (edu) assay, and flow cytometry. |
2022-09-08 |
2023-08-14 |
human |
| Yina Yin, Min Ma, Junxiao Chang, Yufang Kong, Linlin Rui, Guoqiang Chu, Keliang Zhan. LncRNA OIP5-AS1 Mitigates Bupivacaine-Induced Neurotoxicity in Dorsal Root Ganglion Neurons Through Regulating NFAT5 Expression via Sponging miR-34b. Neurotoxicity research. 2022-09-08. PMID:36074257. |
cell proliferation, caspase-3 activity, and apoptosis were assessed via 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2h-tetrazolium bromide (mtt), caspase-3 activity, and terminal deoxynucleotidyl transferase dutp nick end labeling (tunel) assays. |
2022-09-08 |
2023-08-14 |
Not clear |
| Mahdieh Ahmadi Kamalabadi, Ali Neshastehriz, Habib Ghaznavi, Seyed Mohammad Amin. Folate functionalized gold-coated magnetic nanoparticles effect in combined electroporation and radiation treatment of HPV-positive oropharyngeal cancer. Medical oncology (Northwood, London, England). vol 39. issue 12. 2022-09-07. PMID:36071293. |
cell viability and apoptosis rate were determined by mtt and flow cytometry assay. |
2022-09-07 |
2023-08-14 |
Not clear |
| Jinsong Yu, Han Yang, Chunliu Lv, Xiaowei Da. The cytotoxicity of karanjin toward breast cancer cells is involved in the PI3K/Akt signaling pathway. Drug development research. 2022-09-06. PMID:36065628. |
cell viability, proliferation, and apoptosis were examined by mtt (3-(4, 5-dimethyl-2-thiazolyl)-2, 5-diphenyl-tetrazolium bromide), edu (5-ethynyl-2'-deoxyuridine) incorporation, and tunel (terminal deoxynucleotidyl transferase-mediated dutp digoxigenin nick-end labeling) assays, respectively. |
2022-09-06 |
2023-08-14 |
Not clear |
| Kimia Firouzabadi, Ehsan Karimi, Masoud Homayouni Tabriz. Fabrication of bovine serum albumin-polyethylene glycol nanoparticle conjugated-folic acid loaded-naringenin as an efficient carrier bio-macromolecule for suppression of cancer cells. Biotechnology and applied biochemistry. 2022-09-05. PMID:36059122. |
the physicochemical properties of bsa-peg-fa-ng-nps were investigated by dls, sem electron microscopy, and ftir methods, after which their effects were evaluated on the apoptosis mechanism via mtt, flow cytometry, and qpcr methods. |
2022-09-05 |
2023-08-14 |
cattle |
| Banita Thakur, Lekha Saha, Alka Bhati. Relative refractoriness of breast cancer cells to tumour necrosis factor-α induced necroptosis. Clinical and experimental pharmacology & physiology. 2022-09-02. PMID:36054417. |
cell viability, apoptosis, and necroptosis were assessed using mtt and annexin-v/pi assays, respectively. |
2022-09-02 |
2023-08-14 |
Not clear |