| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jie Chen, Puyan Qin, Zhanxia Tao, Weijian Ding, Yunlong Yao, Weifang Xu, Dengke Yin, Song Ta. Anticancer Activity of Methyl Protodioscin against Prostate Cancer by Modulation of Cholesterol-Associated MAPK Signaling Pathway via FOXO1 Induction. Biological & pharmaceutical bulletin. vol 46. issue 4. 2023-04-02. PMID:37005301. |
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt), wound healing, transwell, and flow cytometer assays revealed that mpd suppressed proliferation, migration, cell cycle, and invasion and induced apoptosis of du145 cells. |
2023-04-02 |
2023-08-14 |
mouse |
| Vanesa Sánchez-Martín, Paloma Morales, Amaia Iriondo-DeHond, Xavier F Hospital, Manuela Fernández, Eva Hierro, Ana I Haz. Differential Apoptotic Effects of Bee Product Mixtures on Normal and Cancer Hepatic Cells. Antioxidants (Basel, Switzerland). vol 12. issue 3. 2023-03-29. PMID:36978864. |
the cytotoxic effects of samples were analyzed using the mtt (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay (0-250 mg/ml) and the effects on apoptosis were analyzed using cell cycle analysis, tdt-dutp terminal nick-end labeling (tunel) assay, dr5 (death receptor 5) and bax (bcl-2-associated x) activation, and caspases 8, 9, and 3 activities. |
2023-03-29 |
2023-08-14 |
bee |
| Martina Spada, Cristina Piras, Giulia Diana, Vera Piera Leoni, Daniela Virginia Frau, Gabriele Serreli, Gabriella Simbula, Roberto Loi, Antonio Noto, Federica Murgia, Paola Caria, Luigi Atzor. Glutamine Starvation Affects Cell Cycle, Oxidative Homeostasis and Metabolism in Colorectal Cancer Cells. Antioxidants (Basel, Switzerland). vol 12. issue 3. 2023-03-29. PMID:36978930. |
the growth and proliferation rate, colony-forming capacity, apoptosis, cell cycle, redox homeostasis and metabolomic analysis were evaluated by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide test (mtt), flow cytometry, high-performance liquid chromatography and gas chromatography/mass spectrometry techniques. |
2023-03-29 |
2023-08-14 |
Not clear |
| Der-An Tsao, Yu-Chien Wang, Shang-Tao Chien, Shih-Yi Lin, Huoy-Rou Chan. Fucoidan enhances the effect of chemotherapeutic drug against drug-resistant lung cancer cells. Pakistan journal of pharmaceutical sciences. vol 36. issue 1. 2023-03-27. PMID:36967501. |
cell culture, mtt assay, wound healing assay, gelatin zymography assay, dna fragmentation assay, apoptosis assay, reverse transcription polymerase chain reaction (rt-pcr) western blot analysis was adopted. |
2023-03-27 |
2023-08-14 |
Not clear |
| Shaghayegh Saharkhiz, Atefeh Zarepour, Ali Zarrab. A new theranostic pH-responsive niosome formulation for Doxorubicin delivery and bio-imaging against breast cancer. International journal of pharmaceutics. 2023-03-23. PMID:36958608. |
biological features and imaging ability of the nanoparticles were also evaluated by mtt assay, apoptosis assay, and fluorescence microscopy. |
2023-03-23 |
2023-08-14 |
Not clear |
| Tohid Piri-Gharaghie, Ghazal Ghajari, Maryam Hassanpoor, Neda Jegargoshe-Shirin, Mona Soosanirad, Shahoo Khayati, Ali Farhadi-Biregani, Amir Mirzae. Investigation of antibacterial and anticancer effects of novel niosomal formulated Persian Gulf Sea cucumber extracts. Heliyon. vol 9. issue 3. 2023-03-20. PMID:36938478. |
the effect of niosome-encapsulated sce on cell proliferation and apoptosis induction was studied using mtt and annexin v, respectively. |
2023-03-20 |
2023-08-14 |
Not clear |
| Asma Boukhalfa, Sally R Robinson, Dawn M Meola, Nicholas A Robinson, Lauren A Ling, Joey N LaMastro, Jenica N Upshaw, Lakshmi Pulakat, Iris Z Jaffe, Cheryl A London, Howard H Chen, Vicky K Yan. Using cultured canine cardiac slices to model the autophagic flux with doxorubicin. PloS one. vol 18. issue 3. 2023-03-17. PMID:36928870. |
cell viability and apoptosis were quantified with mtt assay and tunel staining. |
2023-03-17 |
2023-08-14 |
Not clear |
| Yagang Mu, Jian Wang, Guang L. Sphingosine kinase-2 silencing modulates sensitivity of HT-29 human colorectal cancer cells to paclitaxel-induced cell death through altering apoptosis-related proteins. Chemical biology & drug design. 2023-03-17. PMID:36929215. |
proliferation and apoptosis were evaluated by mtt assay, and trypan blue staining and elisa, respectively. |
2023-03-17 |
2023-08-14 |
human |
| Khushbu Kumari, Himadri Tanaya Behera, Priyadarshini Pratikshya Nayak, Adrija Sinha, Aditya Nandi, Aishee Ghosh, Utsa Saha, Mrutyunjay Suar, Pritam Kumar Panda, Suresh K Verma, Vishakha Rain. Amelioration of lipopeptide biosurfactants for enhanced antibacterial and biocompatibility through molecular antioxidant property by methoxy and carboxyl moieties. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 161. 2023-03-12. PMID:36906974. |
moreover, the cellular cytotoxicity was estimated by mtt and other cellular assays revealing the phenomenon as the dose-dependent induction of apoptosis due to free radical scavenging with an lc50 of 55.6 ± 2.3 mg/ml. |
2023-03-12 |
2023-08-14 |
Not clear |
| Pedro Barrios-Bernal, José Lucio-Lozada, Maritza Ramos-Ramírez, Norma Hernández-Pedro, Oscar Arriet. A Novel Combination of Sotorasib and Metformin Enhances Cytotoxicity and Apoptosis in KRAS-Mutated Non-Small Cell Lung Cancer Cell Lines through MAPK and P70S6K Inhibition. International journal of molecular sciences. vol 24. issue 5. 2023-03-11. PMID:36901764. |
cellular cytotoxicity was evaluated by an mtt assay, apoptosis induction through flow cytometry, and mapk and mtor pathways were assessed by western blot. |
2023-03-11 |
2023-08-14 |
Not clear |
| Vijay Patel, Unnati Joshi, Anand Joshi, Tarun Kumar Upadhyay, Lamya Ahmed Al-Keridis, Mohd Saee. Cytotoxicity Analysis for the Hydroxyl Functionalized MWCNT Reinforced PMMA Nanocomposites in Oral Squamous Carcinoma (KB) Cells. Polymers. vol 15. issue 5. 2023-03-11. PMID:36904431. |
in this particular research study, a unique three-dimensional mixing technique was used to incorporate multi-walled carbon nanotubes (mwcnts) into polymethyl methacrylate (pmma), and the kb cell line was used in the analysis of cytotoxicity, apoptosis detection, and cell viability using the mtt assay protocol. |
2023-03-11 |
2023-08-14 |
Not clear |
| Sanaz Ranapour, Nasrin Motame. Effect of Silibinin on the Expression of Mir-20b, Bcl2L11, and Erbb2 in Breast Cancer Cell Lines. Molecular biotechnology. 2023-03-11. PMID:36905464. |
at first, cell viability, apoptosis, and cell cycle arrest-inducing capacity of sb were examined using mtt and flow cytometry analysis, respectively. |
2023-03-11 |
2023-08-14 |
Not clear |
| Mehmet Ali Karaselek, Serkan Kuccukturk, Tugce Duran, Ahmed Nuri Kursunlu, Mustafa Ozmen, Ceren Bozdag, Selman Alkan, Alper Varman, Mehmet Aykut Yildirim, Tevfik Kucukkartallar, Celalettin Vatanse. Effective anticancer agents based-on two Pillar[5]arene derivatives for pancreas cancer cell lines: synthesis, apoptotic effect, caspase pathway. Investigational new drugs. 2023-03-11. PMID:36905565. |
on the contrary, although mtt analysis showed cytotoxic effect in bxpc-3 cell line treated with two pillar[5]arene derivatives, the apoptosis pathway was not active. |
2023-03-11 |
2023-08-14 |
Not clear |
| Jing Zhang, Yang Li, Ji-Guo Wang, Jing-Yu Feng, Guo-Dong Huang, Chang-Guo Lu. Dihydroartemisinin Affects STAT3/DDA1 Signaling Pathway and Reverses Breast Cancer Resistance to Cisplatin. The American journal of Chinese medicine. 2023-03-09. PMID:36891981. |
cell proliferation, viability, and apoptosis were evaluated using colony formation, mtt, and flow cytometry assays, respectively. |
2023-03-09 |
2023-08-14 |
Not clear |
| Bao-Feng Song, Li-Zhe Xu, Kun Jiang, Fan Chen. MiR-124-3p inhibits tumor progression in prostate cancer by targeting EZH2. Functional & integrative genomics. vol 23. issue 2. 2023-03-08. PMID:36884182. |
the cell viability and apoptosis were assessed by flow cytometry and mtt test. |
2023-03-08 |
2023-08-14 |
Not clear |
| Arian Farokh, Mehrab Pourmadadi, Hamid Rashedi, Fatemeh Yazdian, Mona Navaei-Nigje. Assessment of synthesized chitosan/halloysite nanocarrier modified by carbon nanotube for pH-sensitive delivery of curcumin to cancerous media. International journal of biological macromolecules. 2023-03-07. PMID:36882143. |
an mtt assay was also carried out, and the results illustrated apoptosis induction on mcf-7 cells and exhibited ameliorated cytotoxicity of the drug-loaded nanocomposite compared to the free curcumin. |
2023-03-07 |
2023-08-14 |
Not clear |
| Mahdie Mousavi, Fereshteh Koosha, Ali Neshastehri. Chemo-radiation therapy of U87-MG glioblastoma cells using SPIO@AuNP-Cisplatin-Alginate nanocomplex. Heliyon. vol 9. issue 3. 2023-03-06. PMID:36873545. |
following the treatments, apoptosis and cell viability were evaluated in each treatment group using flow cytometry and the mtt assay, respectively. |
2023-03-06 |
2023-08-14 |
human |
| Xiao Han, Jiayan Huang, Jia Lu, Feng He, Fang Wang, Shuangfeng Li, Hao Zhong, Haiyang Yu, Weiling P. Active compounds and potential targets of Shuganning injection in the treatment of hepatocellular carcinoma by network pharmacology and in vitro validation. Naunyn-Schmiedeberg's archives of pharmacology. 2023-03-04. PMID:36869905. |
the in vitro test of the effects and mechanism of vanillin and baicalein was elucidated by mtt, western blot, immunofluorescence, and apoptosis analysis. |
2023-03-04 |
2023-08-14 |
Not clear |
| Qing Zhou, Deshui Kong, Wenzhi Li, Zhengzheng Shi, Yao Liu, Rui Sun, Xiaohong Ma, Chunping Qiu, Zhiming Liu, Yixin Hou, Jie Jian. LncRNA HOXB-AS3 binding to PTBP1 protein regulates lipid metabolism by targeting SREBP1 in endometrioid carcinoma. Life sciences. 2023-03-01. PMID:36858312. |
colony formation assay, mtt assay, flow cytometry and apoptosis assay, and transwell assay were used to verify the role of hoxb-as3 in ec. |
2023-03-01 |
2023-08-14 |
Not clear |
| Saad Alkahtani, Norah S Al-Johani, Saud Alarifi, Mohd Afza. Cytotoxicity Mechanisms of Blue-Light-Activated Curcumin in T98G Cell Line: Inducing Apoptosis through ROS-Dependent Downregulation of MMP Pathways. International journal of molecular sciences. vol 24. issue 4. 2023-02-25. PMID:36835252. |
the therapeutic effect of curcumin, in both the absence and presence of blue light, was measured by the mtt assay and apoptosis progression using flow cytometry. |
2023-02-25 |
2023-08-14 |
Not clear |