| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lü Guohua, Ren Wu, Bing Wang, Li Lei, Yunchao Li, Xinyi Li, Haoyu He, Xiaoxiao Wang, Kuang Le. SPTLC2 ameliorates chondrocyte dysfunction and extracellular matrix metabolism disturbance in vitro and in vivo in osteoarthritis. Experimental cell research. 2023-02-24. PMID:36828166. |
cell viability and apoptosis were measured using mtt and flow cytometry analyses; sptlc2 overexpression enhanced the oa chondrocyte viability and decreased apoptotic rate. |
2023-02-24 |
2023-08-14 |
rat |
| Gholam Abbas Ghorbankhani, Ali Mohammadi, Nasrin Kazemipur, Solmaz Morovati, Behrouz Gharesi Fard, Saeed Nazifi Habibabadi, Mahdi Hashempour Sadeghia. Apoptotic activity of Newcastle disease virus in comparison with nisin A in MDA-MB-231 cell line. Veterinary research forum : an international quarterly journal. vol 14. issue 1. 2023-02-23. PMID:36816859. |
the oncolytic effects of these treatments were analyzed by different cytotoxic and apoptosis techniques including trypan blue staining, mtt assay, acridine orange (eb/ao) staining, colony assay and flow cytometry over time. |
2023-02-23 |
2023-08-14 |
Not clear |
| Zahra Ghaemi, Seyed Javad Mowla, Bahram Mohammad Soltan. Novel splice variants of LINC00963 suppress colorectal cancer cell proliferation via miR-10a/miR-143/miR-217/miR-512-mediated regulation of PI3K/AKT and Wnt/β-catenin signaling pathways. Biochimica et biophysica acta. Gene regulatory mechanisms. 2023-02-22. PMID:36804476. |
at cellular levels, linc00963-v2/-v3 overexpression suppressed cell proliferation, viability, and migration while increasing the apoptosis of crc cell lines, detected by pi flow cytometry, colony formation, mtt, rt-qpcr, wound-healing, transwell, annexinv-pe/7aad, caspase3/7 activity assays, and hoechst/pi-ao/eb staining. |
2023-02-22 |
2023-08-14 |
Not clear |
| Fei Li, Aiqin Niu, Kangjun Zhao, Jianbing Feng, Ying Che. GRIM-19 in asthenozoospermia regulates GC-2 spd cell proliferation, apoptosis and migration. Scientific reports. vol 13. issue 1. 2023-02-22. PMID:36813832. |
mtt assays were used to assess cell proliferations, flow cytometry was performed to assess cell apoptosis, wound‑healing was performed to measure cell migration. |
2023-02-22 |
2023-08-14 |
Not clear |
| Jinsu Hwang, Jong-Seong Park, Mahesh Ramalingam, Byeong C Kim, Han-Seong Jeong, Sujeong Jan. Neuroprotective Effects of a Wnt Antagonist in Quinolinic Acid-Induced Excitotoxicity in N18D3 Cells. Cellular and molecular biology (Noisy-le-Grand, France). vol 68. issue 8. 2023-02-21. PMID:36800814. |
an mtt assay and dapi staining were used to evaluate cell viability and apoptosis, respectively, demonstrating that box5 protected the cells from apoptotic death. |
2023-02-21 |
2023-08-14 |
Not clear |
| Faranak Gholipour, Mohammad Amini, Behzad Baradaran, Ahad Mokhtarzadeh, Morteza Eskandan. Anticancer properties of curcumin-treated Lactobacillus plantarum against the HT-29 colorectal adenocarcinoma cells. Scientific reports. vol 13. issue 1. 2023-02-21. PMID:36801895. |
moreover, flow cytometry analyses of apoptosis and cell cycle confirmed dapi staining and mtt assay results and stipulated the increased occurrence of programmed cell death (apoptosis) in cur-cfs-treated cells (~ 57.65%) compared to cfs-treated cells (~ 47%). |
2023-02-21 |
2023-08-14 |
Not clear |
| Hongguang Sheng, Jun Xiong, Danying Yan. Protective Effect of Sevoflurane Preconditioning on Cardiomyocytes Against Hypoxia/Reoxygenation Injury by Modulating Iron Homeostasis and Ferroptosis. Cardiovascular toxicology. 2023-02-17. PMID:36800141. |
mtt was taken to assess the viability of each group of cells, flow cytometry to detect cell apoptosis, and qrt-pcr or western blot to detect the expression of iron metabolism-related proteins and apoptosis-related proteins in the cells. |
2023-02-17 |
2023-08-14 |
rat |
| Mariam Sanjari-Pour, Nassim Faridi, Ping Wang, S Zahra Bathai. Protective effect of saffron carotenoids against amyloid beta-induced neurotoxicity in differentiated PC12 cells via the unfolded protein response and autophagy. Phytotherapy research : PTR. 2023-02-16. PMID:36794286. |
the mtt assay, flow cytometry, and elevated p-jnk, p-bcl-2, and c-parp indicated the aβos-induced apoptosis in differentiated pc12 cells. |
2023-02-16 |
2023-08-14 |
Not clear |
| Lei Jin, Karrie Mei-Yee Kiang, Stephen Yin Cheng, Gilberto Ka-Kit Leun. Pharmacological inhibition of serine synthesis enhances temozolomide efficacy by decreasing O Laboratory investigation; a journal of technical methods and pathology. vol 102. issue 2. 2023-02-12. PMID:36775408. |
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt), flowcytometry and colony formation assays demonstrated that nct503 worked synergistically with tmz in suppressing gbm cell growth and inducing apoptosis in t98g and u118 cells in vitro. |
2023-02-12 |
2023-08-14 |
Not clear |
| Jing Zhang, Meng Chen, Jie Liu, Dongdong Peng, Zong Dai, Xiaoyong Zou, Zhanchao L. A Knowledge-Graph-Based Multimodal Deep Learning Framework for Identifying Drug-Drug Interactions. Molecules (Basel, Switzerland). vol 28. issue 3. 2023-02-11. PMID:36771157. |
moreover, the identified interactions between topotecan and dantron by kgcn_nfm were validated through mtt assays, apoptosis experiments, cell cycle analysis, and molecular docking. |
2023-02-11 |
2023-08-14 |
Not clear |
| Chenxi Wang, Chenyang Huang, Jiali Wang, Jianfeng Ye, Zhiqiang Xue, Jian Zhang, Yuke Re. Ginsenoside Rg5 attenuates hypoxia-induced cardiomyocyte apoptosis via regulating theAkt pathway. Chemical biology & drug design. 2023-02-10. PMID:36762503. |
in this study, following isolation and culture of ventricular myocardial cells from neonatal rats, the appropriate concentration of rg5 was determined using the mtt assay, the effect of rg5 on apoptosis was assessed employing tunel staining and flow cytometry assays. |
2023-02-10 |
2023-08-14 |
rat |
| Wang Yiou, Wang Zhihong, Zhu Shibai, Li Shanni, Qian Wenwe. MiR-326 regulates cell proliferation and apoptosis in fibroblast-like synoviocytes in rheumatoid arthritis. Human cell. 2023-02-07. PMID:36749538. |
mtt assay and flow cytometry were conducted to explore the biological function of mir-326. our data revealed that the upregulation of mir-326 suppressed cell proliferation and induced apoptosis in ra-fls. |
2023-02-07 |
2023-08-14 |
mouse |
| Shurong Zheng, Weida Fu, Qidi Huang, Jieyu Zhou, Kangkang Lu, Junwei Gu, Ruimin Ma, Guilong Gu. LncRNA PRKCQ-AS1 regulates paclitaxel resistance in triple-negative breast cancer cells through miR-361-5p/PIK3C3 mediated autophagy. Clinical and experimental pharmacology & physiology. 2023-02-03. PMID:36732923. |
cell viability, apoptosis, migration, and invasion were assessed by performing mtt, flow cytometry assay, and transwell assay. |
2023-02-03 |
2023-08-14 |
Not clear |
| Xiujuan Deng, Haigen Wu, Liping Xiong, Mouxi Wu, Jinfu Cao, Jing Liu, Wenyang Xi. MiR-92a regulates PTEN/Akt signaling axis to promote paclitaxel resistance in ovarian cancer cells. Acta biochimica Polonica. 2023-02-03. PMID:36735765. |
the cell viability and apoptosis were detected by mtt, colony formation and flow cytometry assay, respectively. |
2023-02-03 |
2023-08-14 |
Not clear |
| Siyuan Chen, Huili Ma, Mintao Li, Zhuting Jia, Xi Chen, Naitong B. Long Noncoding RNA NORAD Promotes Fracture Healing through Interacting with Osteoblast Differentiation via Targeting miR-26a. BioMed research international. vol 2023. 2023-02-02. PMID:36726840. |
the proliferation, differentiation, and apoptosis of osteoblasts were analyzed by mtt assay, elisa, and flow cytometry. |
2023-02-02 |
2023-08-14 |
Not clear |
| Cheng-Hsun Lin, Kuang-Hsuan Lin, Hsiang-Ju Ku, Kun-Ching Lee, Song-Shei Lin, Fei-Ting Hs. Amentoflavone induces caspase-dependent/-independent apoptosis and dysregulates cyclin-dependent kinase-mediated cell cycle in colorectal cancer in vitro and in vivo. Environmental toxicology. 2023-02-02. PMID:36727907. |
we identified the cytotoxicity, apoptosis effect, cell cycle alteration, dna damage induction and tumor progression inhibition of amentoflavone in ht-29 model by using mtt assay, flow cytometry, immunofluorescence (if) staining, western blotting and animal experiments. |
2023-02-02 |
2023-08-14 |
Not clear |
| Jie Feng, Wei He, Jian Xia, Qing Huang, Jie Yang, Wen-Ping Gu, Ning Zhang, Yun-Hai Li. Human umbilical cord mesenchymal stem cells-derived exosomal circDLGAP4 promotes angiogenesis after cerebral ischemia-reperfusion injury by regulating miR-320/KLF5 axis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 37. issue 3. 2023-02-01. PMID:36723877. |
then, cell viability, migration, apoptosis, and tube formation were measured by mtt, flow cytometry, transwell, and tube formation assays. |
2023-02-01 |
2023-08-14 |
human |
| Xiuyun Li, Chenglun Zhang, Enhui Wu, Liang Han, Xiangliang Deng, Zhongfeng Sh. UPLC-Q-TOF/MS-Based Metabolomics Approach Reveals Osthole Intervention in Breast Cancer 4T1 Cells. International journal of molecular sciences. vol 24. issue 2. 2023-01-21. PMID:36674685. |
the mtt, pi, and annexin v-fitc/pi methods were used to evaluate the effects of ost-treated and untreated 4t1 cells on viability, cell cycle, and apoptosis, respectively. |
2023-01-21 |
2023-08-14 |
Not clear |
| Melika Loriamini, Melissa M Lewis-Bakker, Kayluz Frias Boligan, Siming Wang, Mairead B Holton, Lakshmi P Kotra, Donald R Branc. Small Molecule Drugs That Inhibit Phagocytosis. Molecules (Basel, Switzerland). vol 28. issue 2. 2023-01-21. PMID:36677815. |
subsequent evaluation via mtt viability, ldh release, and apoptosis, led to the selection of two lead compounds with negligible toxicity and high efficacy. |
2023-01-21 |
2023-08-14 |
Not clear |
| Izabela Szymczak-Pajor, Józef Drzewoski, Ewa Świderska, Justyna Strycharz, Anna Gabryanczyk, Jacek Kasznicki, Marta Bogdańska, Agnieszka Śliwińsk. Metformin Induces Apoptosis in Human Pancreatic Cancer (PC) Cells Accompanied by Changes in the Levels of Histone Acetyltransferases (Particularly, p300/CBP-Associated Factor (PCAF) Protein Levels). Pharmaceuticals (Basel, Switzerland). vol 16. issue 1. 2023-01-21. PMID:36678613. |
the cells were exposed to metformin, an hat inhibitor (hati), or a combination of an hati with metformin for 24, 48, or 72 h. cell viability was determined using an mtt assay, and the percentage of early apoptotic cells was determined with an annexin v-cy3 apoptosis detection assay kit. |
2023-01-21 |
2023-08-14 |
human |