| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Haibing Gao, Xiangmei Wang, Huaxi Ma, Shenglong Lin, Dongqing Zhang, Wenjun Wu, Ziyuan Liao, Mengyun Chen, Hanhui Ye, Qin Li, Minghua Lin, Dongliang L. LncRNA CCAT2, involving miR-34a/TGF-β1/Smad4 signaling, regulate hepatic stellate cells proliferation. Scientific reports. vol 12. issue 1. 2022-12-09. PMID:36482069. |
the effects of ccat2 and mir-34a-5p on cell proliferation and apoptosis were verified by mtt assay, colony formation assay, and flow cytometry assay. |
2022-12-09 |
2023-08-14 |
Not clear |
| Tao Li, Hong Ge, Qingyan Yang, Junmei Wang, Qian Yin, Hongbin Wang, Gaolei Ho. Oncogenic role of microRNA-19b-3p-mediated SOCS3 in glioma through activation of JAK-STAT pathway. Metabolic brain disease. 2022-12-09. PMID:36484970. |
cell senescence was assessed by β-galactosidase staining, proliferation by mtt assay and apoptosis by flow cytometry following gain- and/or loss-of-function of mir-19b-3p or socs3. |
2022-12-09 |
2023-08-14 |
mouse |
| Yang Yang, Xiaoli Zheng, Peizan Ni, Dingjie Li, Qinfu Dan, Xiaohui Wang, Yunhan Wang, Yanan Sun, Kangdong Liu, Zigang Dong, Hong G. Targeting the STAT5A/IDO1 axis overcomes radioresistance and reverses the immunosuppressive tumor microenvironment in NSCLC. International journal of oncology. vol 62. issue 1. 2022-12-01. PMID:36453241. |
mtt assay, immunofluorescence, apoptosis analysis, cell cycle analysis, and c57bl/6 and balb/c nude mouse tumor models were utilized to evaluate the roles of the stat5a/ido1/kynurenine axis in radioresistance and in the immune microenvironment of nsclc. |
2022-12-01 |
2023-08-14 |
mouse |
| Amir-Reza Javanmard, Amin Jahanbakhshi, Hossein Nemati, Seyed Javad Mowla, Bahram M Soltan. ADAMTS9-AS1 Long Non‑coding RNA Sponges miR‑128 and miR-150 to Regulate Ras/MAPK Signaling Pathway in Glioma. Cellular and molecular neurobiology. 2022-11-30. PMID:36449154. |
at the cellular level, adamts9-as1 overexpression brought about reduced sub-g1 cell population, increased proliferation rate, reduced apoptosis level, increased migration rate, shortened bax/bcl2 ratio, induced emt, and stemness characteristics of transfected cells, detected by flow cytometry, mtt assay, scratch test, and rt-qpcr. |
2022-11-30 |
2023-08-14 |
Not clear |
| Zhang-Yong Ren, Bing Pan, Fang-Fei Wang, Shao-Cheng Lyu, Qiang H. Effects of different preservation methods of human iliac veins. Cell and tissue banking. 2022-11-28. PMID:36441442. |
survival and apoptosis of vascular cell were evaluated by mtt assay and tunel fluorescence staining. |
2022-11-28 |
2023-08-14 |
human |
| Pegah Kiamehr, Minoo Shahidi, Amir Samii, Farhad Zake. Dual Effects of Resveratrol on the Expression and Secretion of Angiogenic Factors. International journal of molecular and cellular medicine. vol 11. issue 1. 2022-11-18. PMID:36397806. |
the effects of rsv on huvecs and jurkat cell viability and apoptosis were measured by mtt and annexin-v/pi methods. |
2022-11-18 |
2023-08-14 |
human |
| Fang Wen, Zhigang Tan, Dezhi Huang, Yugang Jiang, Jun Xian. LncRNA PVT1 Promotes Neuronal Cell Apoptosis and Neuroinflammation by Regulating miR-488-3p/FOXD3/SCN2A Axis in Epilepsy. Neurochemical research. 2022-11-15. PMID:36378391. |
mtt assay and tunel staining were conducted to assess cell viability and apoptosis, respectively. |
2022-11-15 |
2023-08-14 |
rat |
| Rui Zhang, Ziqi Meng, Xuwei Wu, Meihua Zhang, Zhengri Piao, Tiefeng Ji. PD-L1/p-STAT3 promotes the progression of NSCLC cells by regulating TAM polarization. Journal of cellular and molecular medicine. 2022-11-14. PMID:36372977. |
after constructing the co-culture system and conditioned medium system, the proliferation, apoptosis, metastasis, angiogenesis, emt process and stemness of nsclc were detected by mtt, flow cytometry, transwell, endothelial cell tube formation and western blot assays. |
2022-11-14 |
2023-08-14 |
Not clear |
| Chunli Li, Jiejun Chi, Hongyan Dai, Ming Liang, Yangyang Wang, Songxin Tian, Huiyan Zhu, Hai X. Salidroside attenuates cerebral ischemia/reperfusion injury by regulating TSC2-induced autophagy. Experimental brain research. 2022-11-14. PMID:36374318. |
the results of flow cytometry and 3-(4, 5-dimethylthiazolyl-2)-2,5-diphenyltetrazolium bromide (mtt) assays showed that sal reduced apoptosis, enhanced cell viability and protected neuronal cells from damage by decreasing lactate dehydrogenase (ldh) activity. |
2022-11-14 |
2023-08-14 |
rat |
| Miguel Alcaraz, Amparo Olivares, Marina Andreu-Gálvez, Daniel Gyingiri Achel, Ana María Mercado, Miguel Alcaraz-Saur. Paradoxical Radiosensitizing Effect of Carnosic Acid on B16F10 Metastatic Melanoma Cells: A New Treatment Strategy. Antioxidants (Basel, Switzerland). vol 11. issue 11. 2022-11-11. PMID:36358539. |
radioprotective capacity was evaluated by clonogenic cell survival, mtt, apoptosis and intracellular glutathione assays comparing radiosensitive cells (human prostate epithelium, pnt2) with radioresistant cells (murine metastatic melanoma, b16f10). |
2022-11-11 |
2023-08-14 |
human |
| Grzegorz Adamczuk, Ewelina Humeniuk, Kamila Adamczuk, Aneta Grabarska, Jarosław Dudk. 2,4-Dinitrophenol as an Uncoupler Augments the Anthracyclines Toxicity against Prostate Cancer Cells. Molecules (Basel, Switzerland). vol 27. issue 21. 2022-11-11. PMID:36364051. |
the synergistic effect of the anthracyclines and 2,4-dnp was determined using an mtt assay, apoptosis detection and a cell cycle analysis. |
2022-11-11 |
2023-08-14 |
Not clear |
| Soumya Menon, Santhoshkumar Jayakodi, Kanti Kusum Yadav, Prathap Somu, Mona Isaq, Venkat Kumar Shanmugam, Amballa Chaitanyakumar, Nagaraj Basavegowd. Preparation of Paclitaxel-Encapsulated Bio-Functionalized Selenium Nanoparticles and Evaluation of Their Efficacy against Cervical Cancer. Molecules (Basel, Switzerland). vol 27. issue 21. 2022-11-11. PMID:36364115. |
quantitative evaluation of anti-cancer properties was performed via mtt analysis, apoptosis, gene expression analysis, cell cycle arrest, and over-production of ros. |
2022-11-11 |
2023-08-14 |
Not clear |
| Zhe Li, Yan-Long Rong, Yuan-Shi Zhan. MiR-33-5p alleviates spinal cord injury in rats and protects PC12 cells from lipopolysaccharide-induced apoptosis. The Kaohsiung journal of medical sciences. 2022-11-10. PMID:36354186. |
moreover, as mtt assays and flow cytometry showed, the suppressive effects of mir-33-5p upregulation on cell apoptosis were attenuated by rps6kb1 upregulation. |
2022-11-10 |
2023-08-14 |
rat |
| Azra Salehi, Atefe Rezaei, Mohammad Sadegh Damavandi, Mohammad Saeed Kharazmi, Seid Mahdi Jafar. Almond gum-sodium caseinate complexes for loading propolis extract: Characterization, antibacterial activity, release, and in-vitro cytotoxicity. Food chemistry. vol 405. issue Pt A. 2022-11-09. PMID:36351317. |
apoptosis evaluation and mtt assay confirmed that the encapsulated propolis induces lower cytotoxicity than pure propolis against fibroblast cell line possibly due to the delayed release of propolis. |
2022-11-09 |
2023-08-14 |
Not clear |
| Lijing Hou, Shuang Li, Shasha Li, Ru Wang, Mengke Zhao, Xiaomin Li. FTO inhibits oxidative stress by mediating m6A demethylation of Nrf2 to alleviate cerebral ischemia/reperfusion injury. Journal of physiology and biochemistry. 2022-11-03. PMID:36327034. |
flow cytometry and mtt assay were used to detect apoptosis and proliferation in vitro. |
2022-11-03 |
2023-08-14 |
rat |
| Zhendong Shi, Ming Zhao, Tianyu Lin, Jiajia Chen, Xiaomin Qia. A novel Granzymes and miRNA nanocapsules co-delivery system for tumor suppression. Biomedical physics & engineering express. 2022-11-03. PMID:36327448. |
mtt and flow cytometry analysis showed that a synergistic anti-proliferation and promoting apoptosis effect was achieved when the nanocapsules were added into breast cancer cell lines. |
2022-11-03 |
2023-08-14 |
mouse |
| Lijun Wang, Hu Zhao, Ying Fang, Bo Yuan, Yilin Guo, Wuliang Wan. LncRNA CARMN inhibits cervical cancer cell growth via the miR-92a-3p/BTG2/Wnt/β-catenin axis. Physiological genomics. 2022-10-31. PMID:36314369. |
mtt assay, flow cytometry, and transwell assays revealed that carmn overexpression reduced proliferation, migration, and invasion and increased apoptosis rate in cc cells. |
2022-10-31 |
2023-08-14 |
Not clear |
| b' Seda \\xc5\\x9eirin, Hatice G\\xc3\\xbcl Dursun, Canan Ero\\xc4\\x9flu G\\xc3\\xbcne\\xc5\\x9. Composition analysis of Salsola grandis and its effects on colon cancer cells. Anti-cancer agents in medicinal chemistry. 2022-10-28. PMID:36305129.' |
we applied 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide, the thiazolyl blue (mtt) method to evaluate its effects on cell viability, elisa assay, real time pcr and western blot method to reveal its effects on apoptosis. |
2022-10-28 |
2023-08-14 |
Not clear |
| Aleksandra Jovanović Galović, Nataša Jovanović Lješković, Senka Vidović, Jelena Vladić, Nikola Jojić, Milan Ilić, Tatjana Srdić Rajić, Vesna Kojić, Dimitar Jakimo. The Effects of Resveratrol-Rich Extracts of Pharmaceutics. vol 14. issue 10. 2022-10-27. PMID:36297452. |
the cytotoxic effect is assessed by the mtt test and eb/ao staining, levels of apoptosis are determined by annexin v assay, autophagia by ulk-1 expression using western blot and nf-kb activation by p65 elisa. |
2022-10-27 |
2023-08-14 |
Not clear |
| Amineh Ghaderi, Wen Zhong, Mohammad Ali Okhovat, Johanna Aschan, Ann Svensson, Birgitta Sander, Johan Schultz, Thomas Olin, Anders Österborg, Mohammad Hojjat-Farsangi, Håkan Mellsted. A ROR1 Small Molecule Inhibitor (KAN0441571C) Induced Significant Apoptosis of Mantle Cell Lymphoma (MCL) Cells. Pharmaceutics. vol 14. issue 10. 2022-10-27. PMID:36297673. |
cytotoxicity was analyzed by mtt and apoptosis by annexin v/pi staining as well as signaling and apoptotic proteins (wb). |
2022-10-27 |
2023-08-14 |
human |