| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jing He, Xiaoxiang Xi, Peng Cao, Jinxia Zhou, Hui Liu, Na L. Long non-coding RNA GNAS-AS1 knockdown inhibits proliferation and epithelial-mesenchymal transition of lung adenocarcinoma cells via the microRNA-433-3p/Rab3A axis. Open medicine (Warsaw, Poland). vol 18. issue 1. 2023-07-19. PMID:37465347. |
cell proliferation and apoptosis were checked using mtt and flow cytometry, respectively. |
2023-07-19 |
2023-08-14 |
Not clear |
| Rui Tian, Huixin Li, Songjie Ren, Shukui Li, Run Fang, Yang Li. circRNA THBS1 silencing inhibits the malignant biological behavior of cervical cancer cells via the regulation of miR-543/HMGB2 axis. Open medicine (Warsaw, Poland). vol 18. issue 1. 2023-07-19. PMID:37465349. |
cell proliferation and apoptosis were evaluated by mtt and flow cytometry, respectively. |
2023-07-19 |
2023-08-14 |
Not clear |
| Hui Li, Jian Hao, Weimin Y. LncRNA CASC15 inhibition relieves renal fibrosis in diabetic nephropathy through down-regulating SP-A by sponging to miR-424. Open medicine (Warsaw, Poland). vol 18. issue 1. 2023-07-19. PMID:37465354. |
mtt and flow cytometry analysis were carried out to test cell proliferation and apoptosis. |
2023-07-19 |
2023-08-14 |
Not clear |
| Sasenka Vidicevic-Novakovic, Zeljka Stanojevic, Nina Tomonjic, Katarina Karapandza, Janko Zekovic, Tamara Martinovic, Danica Grujicic, Rosanda Ilic, Savo Raicevic, Jelena Tasic, Aleksandra Isakovi. Proapoptotic and proautophagy effect of H1-receptor antagonist desloratadine in human glioblastoma cell lines. Medical oncology (Northwood, London, England). vol 40. issue 8. 2023-07-16. PMID:37452991. |
cytotoxic effect of desloratadine was investigated using mtt and cv assays, while oxidative stress, apoptosis, and autophagy were detected by flow cytometry and immunoblot. |
2023-07-16 |
2023-08-14 |
human |
| Claudia Felici, Anna Passarelli, Paola Cafforio, Vito Racanelli, Patrizia Leone, Marco Tucc. Lenalidomide arrests cell cycle and modulates PD1-dependent downstream mTOR intracellular signals in melanoma cells. Melanoma research. 2023-07-14. PMID:37451673. |
the antiproliferative action of lenalidomide was evaluated on two melanoma cell lines by mtt assay, cell cycle and apoptosis assay. |
2023-07-14 |
2023-08-14 |
Not clear |
| Jinling Qiao, Huizhi Ma, Meirong Chen, Jie Ba. Vitamin D alleviates neuronal injury in cerebral ischemia-reperfusion via enhancing the Nrf2/HO-1 antioxidant pathway to counteract NLRP3-mediated pyroptosis. Journal of neuropathology and experimental neurology. 2023-07-05. PMID:37403613. |
administration of 1,25-vitd3 improved cell viability and inhibited lactate dehydrogenase (ldh) activity and cell apoptosis in ogd/r-stimulated rn-c, as assessed by 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-h-tetrazolium bromide (mtt) assay, ldh activity assays and tdt-mediated dutp nick end labeling (tunel) staining, respectively. |
2023-07-05 |
2023-08-14 |
rat |
| Qing Tian, Ying Guo, Jinfeng Liu, Chao Pang, Qiang Wang, Qi Xie, Jianke L. CircDUS2L (circ_0039908) promotes lung adenocarcinoma progression by upregulating PGAM1 by acting as a miR-590-5p molecular sponge. Journal of biochemical and molecular toxicology. 2023-07-01. PMID:37392398. |
cell proliferation, apoptosis, metastasis, and invasion were assessed by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt), colony formation, 5-ethynyl-2'-deoxyuridine (edu), flow cytometry, and transwell assays. |
2023-07-01 |
2023-08-14 |
Not clear |
| GuangDuo Zhu, XiaoWei Yang, WeiWei Zhou, Xu Lian, YingJie Ha. PLAGL2 induces nucleus pulposus cell apoptosis via regulating RASSF5 expression and thus accelerates intervertebral disc degeneration. Experimental cell research. 2023-06-26. PMID:37364764. |
the impact of plagl2 on the viability, apoptosis, and mitochondria function of np cells was evaluated by mtt assay, tunel, jc1 staining, and flow cytometry assay. |
2023-06-26 |
2023-08-14 |
mouse |
| Hosein Esmaeili, Mehrdad Nasrollahzadeh Sabet, Reza Mosaed, Mohsen Chamanara, Saeid Hadi, Ebrahim Hazrati, Arezoo Farhadi, Mohammad Foad Heidari, Javad Behrooz. Oleanolic acid increases the anticancer potency of doxorubicin in pancreatic cancer cells. Journal of biochemical and molecular toxicology. 2023-06-22. PMID:37345903. |
therefore, we investigated the efficacy of combination therapy by widely used chemotherapy drug doxorubicin (dox) and oleanolic acid (oa) to induction of apoptosis for pancreatic cancer (pc) therapy. the effects of dox, oa, and their combination (dox-oa) were investigated on proliferation and viability of pc cell line (panc-1) by mtt assay. |
2023-06-22 |
2023-08-14 |
Not clear |
| Feng Wang, Ma-ChiCheng Bao, Jing Xu, Lan-Lan Shi, Rui-Ze Niu, Ting-Hua Wang, Jia Li. Scutellarin inhibits the glioma cell proliferation by downregulating BIRC5 to promote cell apoptosis. Journal of cellular and molecular medicine. 2023-06-21. PMID:37340587. |
the wound healing assay, flow cytometry and mtt test were used to detect the effect of scutellarin on the apoptosis and proliferation of glioma cells. |
2023-06-21 |
2023-08-14 |
mouse |
| Hala M ElBadre, Sahar E M El-Deek, Haidi Karam-Allah Ramadan, Mohamed M Elbadr, Dina Sabry, Noran M Ahmed, Amr M Ahmed, Reham I El-Mahd. Potential role of human umbilical cord stem cells-derived exosomes as novel molecular inhibitors of hepatocellular carcinoma growth. Apoptosis : an international journal on programmed cell death. 2023-06-20. PMID:37338718. |
proliferation, apoptosis, and angiogenesis effects were assessed together with the cell viability evaluation by mtt assay in hepg2 cells at 24/48 h. |
2023-06-20 |
2023-08-14 |
human |
| Salman Ghaffari, Soroosh Fateh, Fatemeh Faramarzi, Alireza Rafiei, Mehran Razavipour, Parisa Zafar. The effect of tranexamic acid on synovium of patients undergoing arthroplasty and anterior cruciate ligament reconstruction surgery. Naunyn-Schmiedeberg's archives of pharmacology. 2023-06-15. PMID:37318523. |
mtt assays revealed a significant decrease in cell viability in fls of all groups of patients following treatment with 0.8-60 mg/ml of txa within 24 h. there was a significant increase in cell apoptosis after 24 h of exposure to txa (15 mg/ml) in all groups, especially in ra-fls. |
2023-06-15 |
2023-08-14 |
Not clear |
| Parisa Vasefifar, Souzan Najafi, Rouhollah Motafakkerazad, Mohammad Amini, Sahar Safaei, Basira Najafzadeh, Hajar Alemohammad, Mahdi Jafarlou, Behzad Baradara. Targeting Nanog expression increased Cisplatin chemosensitivity and inhibited cell migration in Gastric cancer cells. Experimental cell research. 2023-06-14. PMID:37315760. |
then, to study cellular viability and apoptosis, mtt assay and annexin v/pi staining were done, respectively. |
2023-06-14 |
2023-08-14 |
human |
| Anna Radajewska, Helena Moreira, Dorota Bęben, Oliwia Siwiela, Anna Szyjka, Katarzyna Gębczak, Paulina Nowak, Jakub Frąszczak, Fathi Emhemmed, Christian D Muller, Ewa Bar. Combination of Irinotecan and Melatonin with the Natural Compounds Wogonin and Celastrol for Colon Cancer Treatment. International journal of molecular sciences. vol 24. issue 11. 2023-06-11. PMID:37298495. |
first, mtt and flow cytometric annexin-v apoptosis assays were performed to determine the cytotoxic effect and the induction of apoptosis. |
2023-06-11 |
2023-08-14 |
Not clear |
| Xianwu Yang, Xiaojuan Tian, Pengcheng Zhao, Zheng Wang, Xuedong Su. Paclitaxel inhibits hepatocellular carcinoma tumorigenesis by regulating the circ_0005785/miR-640/GSK3β. Cell biology international. 2023-06-03. PMID:37269228. |
cell viability, proliferation, invasion, migration, apoptosis, and angiogenesis were detected using 3-(4, 5-dimethyl-2-thiazolyl)-2, 5-diphenyl-2-h-tetrazolium bromide (mtt), colony formation, transwell, wound-healing, flow cytometry, and tube formation assay. |
2023-06-03 |
2023-08-14 |
Not clear |
| Yan Li, Ying Zhang, Lei Gua. MiR-708 regulates the biological behavior of childhood leukemia cells by binding to the 3'utr end of the target gene and reducing the level of the target gene. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 2. 2023-05-25. PMID:37224029. |
mtt assay was used to detect the cell proliferation inhibition rate, flow cytometry was used to detect the apoptosis rate and cell cycle change, the scratch test was used to detect the cell migration capacity, and western blot assay was used to detect the expression of cntfr, apoptosis and jak/stat pathway related proteins. |
2023-05-25 |
2023-08-14 |
human |
| Huiqi Dai, Guoli Wang, Wenmin Cao, Wei Qi, Wei Chen, Hongqian Gu. Stress granules affect the sensitivity of renal cancer cells to sorafenib by sequestering and stabilizing COX‑2 mRNA. Oncology letters. vol 25. issue 6. 2023-05-23. PMID:37216166. |
the results of the mtt assay and cell apoptosis experiment demonstrated that the cytotoxicity of sorafenib was also affected by cox-2 expression and celecoxib enhanced the cytotoxicity of sorafenib against renal cell carcinoma. |
2023-05-23 |
2023-08-14 |
Not clear |
| Farzaneh Zarghampoor, Behnaz Valibeigi, Abbas Behzad-Behbahan. The molecular characteristics of colorectal cancer: Impact of Ibuprofen and hyperthermia. Molecular biology research communications. vol 12. issue 1. 2023-05-18. PMID:37201032. |
this study investigated the effects of hyperthermia and ibuprofen on human colorectal adenocarcinoma cells (ht-29) viability, proliferation, and gene expression related to tumor suppression, wnt signaling pathways, proliferation, and apoptosis the cells were exposed to hyperthermia at 42 or 43°c for 3 hours or ibuprofen at different concentrations (700-1500 μm), and the effects were analyzed through mtt assay, trypan blue staining, and quantitative real-time pcr. |
2023-05-18 |
2023-08-14 |
human |
| Mingyu Chen, Hanyue Li, Xiaolin Xu, Xunxia Bao, Lei Xue, Xinghao Ai, Jian Xu, Ming Xu, Yong Shi, Timing Zhen, Jie Li, Yi Yang, Yang Ji, Zhiliang Fu, Kaichen Xing, Tao Qing, Qiubo Wang, Ping Zhong, Sibo Zh. Identification of RAC1 in promoting brain metastasis of lung adenocarcinoma using single-cell transcriptome sequencing. Cell death & disease. vol 14. issue 5. 2023-05-18. PMID:37202394. |
transitional phase related gene analysis identified rac1 was enriched in metastatic tumor tissue (mtt) preferred gene set functioning as regulated cell death and apoptosis as well as promoted macromolecule organization. |
2023-05-18 |
2023-08-14 |
mouse |
| Claudio Zippilli, Silvia Filippi, Silvia Cesarini, Bruno Mattia Bizzarri, Pauline Conigliaro, Elisa De Marchi, Lorenzo Botta, Raffaele Saladin. Synthesis of Artesunic Acid-Coumarin Hybrids as Potential Antimelanoma Agents. ACS medicinal chemistry letters. vol 14. issue 5. 2023-05-17. PMID:37197457. |
further tests, including cellular proliferation, apoptosis, confocal microscopy, and mtt analyses in the presence of an iron chelating agent, were conducted with the aim of tentatively addressing the mode of action and the pharmacokinetic profile of selected compounds. |
2023-05-17 |
2023-08-14 |
Not clear |