| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hosein Esmaeili, Mehrdad Nasrollahzadeh Sabet, Reza Mosaed, Mohsen Chamanara, Saeid Hadi, Ebrahim Hazrati, Arezoo Farhadi, Mohammad Foad Heidari, Javad Behrooz. Oleanolic acid increases the anticancer potency of doxorubicin in pancreatic cancer cells. Journal of biochemical and molecular toxicology. 2023-06-22. PMID:37345903. |
therefore, we investigated the efficacy of combination therapy by widely used chemotherapy drug doxorubicin (dox) and oleanolic acid (oa) to induction of apoptosis for pancreatic cancer (pc) therapy. the effects of dox, oa, and their combination (dox-oa) were investigated on proliferation and viability of pc cell line (panc-1) by mtt assay. |
2023-06-22 |
2023-08-14 |
Not clear |
| Feng Wang, Ma-ChiCheng Bao, Jing Xu, Lan-Lan Shi, Rui-Ze Niu, Ting-Hua Wang, Jia Li. Scutellarin inhibits the glioma cell proliferation by downregulating BIRC5 to promote cell apoptosis. Journal of cellular and molecular medicine. 2023-06-21. PMID:37340587. |
the wound healing assay, flow cytometry and mtt test were used to detect the effect of scutellarin on the apoptosis and proliferation of glioma cells. |
2023-06-21 |
2023-08-14 |
mouse |
| Hala M ElBadre, Sahar E M El-Deek, Haidi Karam-Allah Ramadan, Mohamed M Elbadr, Dina Sabry, Noran M Ahmed, Amr M Ahmed, Reham I El-Mahd. Potential role of human umbilical cord stem cells-derived exosomes as novel molecular inhibitors of hepatocellular carcinoma growth. Apoptosis : an international journal on programmed cell death. 2023-06-20. PMID:37338718. |
proliferation, apoptosis, and angiogenesis effects were assessed together with the cell viability evaluation by mtt assay in hepg2 cells at 24/48 h. |
2023-06-20 |
2023-08-14 |
human |
| Salman Ghaffari, Soroosh Fateh, Fatemeh Faramarzi, Alireza Rafiei, Mehran Razavipour, Parisa Zafar. The effect of tranexamic acid on synovium of patients undergoing arthroplasty and anterior cruciate ligament reconstruction surgery. Naunyn-Schmiedeberg's archives of pharmacology. 2023-06-15. PMID:37318523. |
mtt assays revealed a significant decrease in cell viability in fls of all groups of patients following treatment with 0.8-60 mg/ml of txa within 24 h. there was a significant increase in cell apoptosis after 24 h of exposure to txa (15 mg/ml) in all groups, especially in ra-fls. |
2023-06-15 |
2023-08-14 |
Not clear |
| Parisa Vasefifar, Souzan Najafi, Rouhollah Motafakkerazad, Mohammad Amini, Sahar Safaei, Basira Najafzadeh, Hajar Alemohammad, Mahdi Jafarlou, Behzad Baradara. Targeting Nanog expression increased Cisplatin chemosensitivity and inhibited cell migration in Gastric cancer cells. Experimental cell research. 2023-06-14. PMID:37315760. |
then, to study cellular viability and apoptosis, mtt assay and annexin v/pi staining were done, respectively. |
2023-06-14 |
2023-08-14 |
human |
| Anna Radajewska, Helena Moreira, Dorota Bęben, Oliwia Siwiela, Anna Szyjka, Katarzyna Gębczak, Paulina Nowak, Jakub Frąszczak, Fathi Emhemmed, Christian D Muller, Ewa Bar. Combination of Irinotecan and Melatonin with the Natural Compounds Wogonin and Celastrol for Colon Cancer Treatment. International journal of molecular sciences. vol 24. issue 11. 2023-06-11. PMID:37298495. |
first, mtt and flow cytometric annexin-v apoptosis assays were performed to determine the cytotoxic effect and the induction of apoptosis. |
2023-06-11 |
2023-08-14 |
Not clear |
| Xianwu Yang, Xiaojuan Tian, Pengcheng Zhao, Zheng Wang, Xuedong Su. Paclitaxel inhibits hepatocellular carcinoma tumorigenesis by regulating the circ_0005785/miR-640/GSK3β. Cell biology international. 2023-06-03. PMID:37269228. |
cell viability, proliferation, invasion, migration, apoptosis, and angiogenesis were detected using 3-(4, 5-dimethyl-2-thiazolyl)-2, 5-diphenyl-2-h-tetrazolium bromide (mtt), colony formation, transwell, wound-healing, flow cytometry, and tube formation assay. |
2023-06-03 |
2023-08-14 |
Not clear |
| Yan Li, Ying Zhang, Lei Gua. MiR-708 regulates the biological behavior of childhood leukemia cells by binding to the 3'utr end of the target gene and reducing the level of the target gene. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 2. 2023-05-25. PMID:37224029. |
mtt assay was used to detect the cell proliferation inhibition rate, flow cytometry was used to detect the apoptosis rate and cell cycle change, the scratch test was used to detect the cell migration capacity, and western blot assay was used to detect the expression of cntfr, apoptosis and jak/stat pathway related proteins. |
2023-05-25 |
2023-08-14 |
human |
| Huiqi Dai, Guoli Wang, Wenmin Cao, Wei Qi, Wei Chen, Hongqian Gu. Stress granules affect the sensitivity of renal cancer cells to sorafenib by sequestering and stabilizing COX‑2 mRNA. Oncology letters. vol 25. issue 6. 2023-05-23. PMID:37216166. |
the results of the mtt assay and cell apoptosis experiment demonstrated that the cytotoxicity of sorafenib was also affected by cox-2 expression and celecoxib enhanced the cytotoxicity of sorafenib against renal cell carcinoma. |
2023-05-23 |
2023-08-14 |
Not clear |
| Farzaneh Zarghampoor, Behnaz Valibeigi, Abbas Behzad-Behbahan. The molecular characteristics of colorectal cancer: Impact of Ibuprofen and hyperthermia. Molecular biology research communications. vol 12. issue 1. 2023-05-18. PMID:37201032. |
this study investigated the effects of hyperthermia and ibuprofen on human colorectal adenocarcinoma cells (ht-29) viability, proliferation, and gene expression related to tumor suppression, wnt signaling pathways, proliferation, and apoptosis the cells were exposed to hyperthermia at 42 or 43°c for 3 hours or ibuprofen at different concentrations (700-1500 μm), and the effects were analyzed through mtt assay, trypan blue staining, and quantitative real-time pcr. |
2023-05-18 |
2023-08-14 |
human |
| Mingyu Chen, Hanyue Li, Xiaolin Xu, Xunxia Bao, Lei Xue, Xinghao Ai, Jian Xu, Ming Xu, Yong Shi, Timing Zhen, Jie Li, Yi Yang, Yang Ji, Zhiliang Fu, Kaichen Xing, Tao Qing, Qiubo Wang, Ping Zhong, Sibo Zh. Identification of RAC1 in promoting brain metastasis of lung adenocarcinoma using single-cell transcriptome sequencing. Cell death & disease. vol 14. issue 5. 2023-05-18. PMID:37202394. |
transitional phase related gene analysis identified rac1 was enriched in metastatic tumor tissue (mtt) preferred gene set functioning as regulated cell death and apoptosis as well as promoted macromolecule organization. |
2023-05-18 |
2023-08-14 |
mouse |
| Claudio Zippilli, Silvia Filippi, Silvia Cesarini, Bruno Mattia Bizzarri, Pauline Conigliaro, Elisa De Marchi, Lorenzo Botta, Raffaele Saladin. Synthesis of Artesunic Acid-Coumarin Hybrids as Potential Antimelanoma Agents. ACS medicinal chemistry letters. vol 14. issue 5. 2023-05-17. PMID:37197457. |
further tests, including cellular proliferation, apoptosis, confocal microscopy, and mtt analyses in the presence of an iron chelating agent, were conducted with the aim of tentatively addressing the mode of action and the pharmacokinetic profile of selected compounds. |
2023-05-17 |
2023-08-14 |
Not clear |
| Qin Tong, Zhangqiang W. Curcumin inhibits colon cancer malignant progression and promotes T cell killing by regulating miR-206 expression. Clinical anatomy (New York, N.Y.). 2023-05-16. PMID:37191314. |
the proliferation and apoptosis of the treated cells were determined by mtt, colony formation assay and flow cytometry. |
2023-05-16 |
2023-08-14 |
human |
| Pengzhou Kong, Xin Yang, Yingying Zhang, Huiling Dong, Xiangchen Liu, Xiaoqin Xu, Xinri Zhang, Yiwei Shi, Mingxia Hou, Bin Son. Palbociclib Enhances Migration and Invasion of Cancer Cells via Senescence-Associated Secretory Phenotype-Related CCL5 in Non-Small-Cell Lung Cancer. Journal of oncology. vol 2022. 2023-05-15. PMID:37181790. |
to test the effect of palbociclib on non-small-cell lung cancer (nsclc) cells, we treated nsclc cells with different concentrations of palbociclib and detected its effects via mtt, migration and invasion assays, and apoptosis test. |
2023-05-15 |
2023-08-14 |
Not clear |
| Yue Peng, Miao Yang, Jiang Lin, Tiejian Zhao, Peng Liu, Qian-Yu Liu, Wei-Qian Gu. [Effects of Pearl Hydrolysate on Hepatic Sinusoidal Endothelial Cell Viability and Capillarization in Liver Fibrosis]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. vol 45. issue 2. 2023-05-08. PMID:37157063. |
methods hepatic sinusoidal endothelial cells (hsec) and hepatic stellate cells (hsc-lx2) were incubated with hepu pearl hydrolysate.the proliferation of hsec and hsc-lx2 was examined by mtt colorimetry.the cell cycle and apoptosis of hsc-lx2 were measured by flow cytometry.the changes of the microstructures such as fenestra and basement membrane of hsec were observed by transmission electron microscopy. |
2023-05-08 |
2023-08-14 |
Not clear |
| Huibing Li, Xin Jin, Mingyao Lai, Yongshi Li, Ruixing Li, Huihui Yang, Baoying Yan. Knockdown of circ_CLIP2 regulates the proliferation, metastasis and apoptosis of glioma cells through miR-641/EPHA3/STAT3 axis. Journal of neurogenetics. 2023-05-02. PMID:37129498. |
cell viability, migration, invasion and apoptosis were examined by mtt assay, tranwell and flow cytometry assays, respectively. |
2023-05-02 |
2023-08-14 |
human |
| Piotr Tomasz Wysocki, Karol Czubak, Anna A Marusiak, Monika Kolanowska, Dominika Nowi. lncRNA DIRC3 regulates invasiveness and IGF signaling in thyroid cancer cells. Endocrine-related cancer. 2023-05-02. PMID:37130273. |
silencing dirc3 in thyroid cancer cell lines (mda-t32 and mda-t120) had a dichotomous phenotypic influence: augmented cell migration and invasiveness, reduced apoptosis, but abrogated the mtt reduction rate. |
2023-05-02 |
2023-08-14 |
Not clear |
| Pei Fan, Yuying Lu, Haidong Wei, Kui Wang, Pengyu Jia, Yuanyuan Zhang, Yan Zhang, Tianyue Wang, Liufei Yang, Jing Zhao, Shuyue Zhang, Haixia Lu, Xinlin Chen, Yong Liu, Pengbo Zhan. Metformin attenuates sevoflurane-induced neurogenesis damage and cognitive impairment: involvement of the Nrf2/G6PD pathway. Metabolic brain disease. 2023-04-29. PMID:37119382. |
mtt assays, immunofluorescence staining, and tunel staining were used to assess the viability, proliferation, differentiation, and apoptosis of nscs. |
2023-04-29 |
2023-08-14 |
rat |
| Wei Hou, Lu Xu, Tao Su, Yunxiao Wu, Yujuan Liu, Yangao We. Hypoxia Induces Tumor-Derived Exosome SNHG16 to Mediate Nasopharyngeal Carcinoma Progression through the miR-23b-5p/MCM6 Pathway. Applied biochemistry and biotechnology. 2023-04-29. PMID:37119503. |
mtt, flow cytometry and transwell were used to detect the effects of them on the proliferation, cycle, apoptosis and invasion ability of npc. |
2023-04-29 |
2023-08-14 |
Not clear |
| Yihui Fu, Lirong Liu, Haihong Wu, Yamei Zheng, Huijuan Zhan, Liang L. LncRNA GAS5 regulated by FTO-mediated m6A demethylation promotes autophagic cell death in NSCLC by targeting UPF1/BRD4 axis. Molecular and cellular biochemistry. 2023-04-29. PMID:37120495. |
cell proliferation and apoptosis were determined using mtt assay, edu assay and flow cytometry. |
2023-04-29 |
2023-08-14 |
Not clear |