| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Abudayyak Mahmoud, Öztaş Ezgi, Arici Merve, Gül Özha. In Vitro Toxicological Assessment of Magnesium Oxide Nanoparticle Exposure in Several Mammalian Cell Types. International journal of toxicology. vol 35. issue 4. 2018-01-10. PMID:27177543. |
for the toxicological assessment, the following assays were used: the particle characterization by transmission electron microscopy, the determination of cellular uptake by inductively coupled plasma-mass spectrometry, mtt and neutral red uptake assays for cytotoxicity, comet assay for genotoxicity, and the determination of malondialdehyde (mda), 8-hydroxydeoxyguanosine, protein carbonyl, and glutathione levels by enzyme-linked immune sorbent assays for the potential of oxidative damage and annexin v-fluorescein isothiocyanate (fitc) apoptosis detection assay with propidium iodide (pi) for apoptosis. |
2018-01-10 |
2023-08-13 |
Not clear |
| Yan Jiang, Qiuli Zhang, Jinsuo Bao, Chenghua Du, Jian Wang, Qiang Tong, Chang Li. Schisandrin B inhibits the proliferation and invasion of glioma cells by regulating the HOTAIR-micoRNA-125a-mTOR pathway. Neuroreport. vol 28. issue 2. 2018-01-10. PMID:27977512. |
the glioma cell lines, u251 and u87, were exposed to sch b, and the cell viability, apoptosis, migration, and invasion were determined using the mtt assay, flow cytometry, and transwell assay, respectively. |
2018-01-10 |
2023-08-13 |
Not clear |
| Kai Wu, Yang Yang, Donglei Liu, Yu Qi, Chunyang Zhang, Jia Zhao, Song Zha. Activation of PPARγ suppresses proliferation and induces apoptosis of esophageal cancer cells by inhibiting TLR4-dependent MAPK pathway. Oncotarget. vol 7. issue 28. 2018-01-09. PMID:27323819. |
ec109 and te10 esophageal cancer cells were treated with 0, 10, 20 and 40 mm of pparg agonist rosiglitazone (rgz) for 24, 48, and 72 h, and the cell viability and apoptosis were detected using methyl thiazolyl tetrazolium (mtt) assay and flow cytometric (fcm) analysis, respectively. |
2018-01-09 |
2023-08-13 |
Not clear |
| Ankit Shah, Anil Kuma. Methamphetamine-mediated endoplasmic reticulum (ER) stress induces type-1 programmed cell death in astrocytes via ATF6, IRE1α and PERK pathways. Oncotarget. vol 7. issue 29. 2018-01-08. PMID:27323860. |
finally, ma-mediated apoptosis was demonstrated via mtt assay and tunel staining. |
2018-01-08 |
2023-08-13 |
mouse |
| Ankit Shah, Anil Kuma. Methamphetamine-mediated endoplasmic reticulum (ER) stress induces type-1 programmed cell death in astrocytes via ATF6, IRE1α and PERK pathways. Oncotarget. vol 7. issue 29. 2018-01-08. PMID:27323860. |
the involvement of er stress in the apoptosis was demonstrated with the help of mtt and tunel assays in the presence of sirna against various er stress proteins. |
2018-01-08 |
2023-08-13 |
mouse |
| S Ahmadi, M Sharifi, R Saleh. Locked nucleic acid inhibits miR-92a-3p in human colorectal cancer, induces apoptosis and inhibits cell proliferation. Cancer gene therapy. vol 23. issue 7. 2018-01-05. PMID:27199220. |
at different times, the expression level of mir-92a-3p, cell vitality, apoptosis and necrosis were studied by qrt-pcr, mtt, annexin-v and propidiumiodide. |
2018-01-05 |
2023-08-13 |
human |
| He-Yan Sun, Kong-Zu Hu, Zong-Sheng Yi. Inhibition of the p38-MAPK signaling pathway suppresses the apoptosis and expression of proinflammatory cytokines in human osteoarthritis chondrocytes. Cytokine. vol 90. 2018-01-04. PMID:27907835. |
cell proliferation and apoptosis were detected by mtt assay and flow cytometry. |
2018-01-04 |
2023-08-13 |
human |
| Xin Chen, Yang Gao, Deheng Li, Yiqun Cao, Bin Ha. LncRNA-TP53TG1 Participated in the Stress Response Under Glucose Deprivation in Glioma. Journal of cellular biochemistry. vol 118. issue 12. 2018-01-02. PMID:28569381. |
mtt, clonogenicity assays, and flow cytometry were performed to detect the cell proliferation and cell apoptosis. |
2018-01-02 |
2023-08-13 |
human |
| Hong Wang, Ying Chen, Nianhui Zhai, Xingxiang Chen, Fang Gan, Hu Li, Kehe Huan. Ochratoxin A-Induced Apoptosis of IPEC-J2 Cells through ROS-Mediated Mitochondrial Permeability Transition Pore Opening Pathway. Journal of agricultural and food chemistry. vol 65. issue 48. 2018-01-02. PMID:29136370. |
the results confirmed that ota induced ipec-j2 cell toxicity by mtt assay and apoptosis by hoechst 33258 staining and flow cytometer analysis. |
2018-01-02 |
2023-08-13 |
Not clear |
| Mohammad Amin Mahjoub, Babak Bakhshinejad, Majid Sadeghizadeh, Sadegh Babasha. Combination treatment with dendrosomal nanocurcumin and doxorubicin improves anticancer effects on breast cancer cells through modulating CXCR4/NF-κB/Smo regulatory network. Molecular biology reports. vol 44. issue 4. 2017-12-27. PMID:28752270. |
mtt assay, annexin v-fitc staining followed by flowcytomety and wound healing assay were used to measure the effects caused by dnc and doxorubicin, alone and in combination, on the viability, apoptosis induction, and migration of mda-mb-231 cells, respectively. |
2017-12-27 |
2023-08-13 |
Not clear |
| Yajie Zhang, Xiaoming Zhou, Lipeng Xu, Lulu Wang, Jinling Liu, Jing Ye, Pengxin Qiu, Qinghua Li. Apoptosis of rat hepatic stellate cells induced by diallyl trisulfide and proteomics profiling in vitro. Canadian journal of physiology and pharmacology. vol 95. issue 5. 2017-12-26. PMID:28177695. |
cell proliferation and apoptosis were determined using tetrazolium dye (mtt) colorimetric assay, bromodeoxyuridine (5-bromo-2'-deoxyuridine; brdu) assay, hoechst 33342 staining, electroscopy, and flow cytometry. |
2017-12-26 |
2023-08-13 |
rat |
| T Wu, L-N Wang, D-R Tang, F-Y Su. SOST silencing promotes proliferation and invasion and reduces apoptosis of retinoblastoma cells by activating Wnt/β-catenin signaling pathway. Gene therapy. vol 24. issue 7. 2017-12-22. PMID:28485721. |
mtt assay, flow cytometry, transwell assay and the starch test were employed to determine the cell proliferation, cell cycle, apoptosis, invasion and migration after transfection. |
2017-12-22 |
2023-08-13 |
mouse |
| Haixia Li, Baoyuan Shi, Yanyun Li, Fengfang Yi. Polydatin inhibits cell proliferation and induces apoptosis in laryngeal cancer and HeLa cells via suppression of the PDGF/AKT signaling pathway. Journal of biochemical and molecular toxicology. vol 31. issue 7. 2017-12-21. PMID:28266802. |
mtt assay and flow cytometry showed that pd inhibited cell proliferation and induced apoptosis in hep-2 and amc-hn-8 cells. |
2017-12-21 |
2023-08-13 |
mouse |
| Ge-Liang Liu, Han-Jie Yang, Bo Liu, Tian Li. Effects of MicroRNA-19b on the Proliferation, Apoptosis, and Migration of Wilms' Tumor Cells Via the PTEN/PI3K/AKT Signaling Pathway. Journal of cellular biochemistry. vol 118. issue 10. 2017-12-21. PMID:28322459. |
mtt assay, propidium iodide (pi) staining, annexin-v/pi double-staining, transwell assay and western blotting were performed to examine cell proliferation, cycle, apoptosis, migration, and invasion, and the protein expressions of pten, p13k, akt, and p-akt. |
2017-12-21 |
2023-08-13 |
human |
| Kewei Ren, Zhen Li, Yahua Li, Wenzhe Zhang, Xinwei Ha. Sulforaphene enhances radiosensitivity of hepatocellular carcinoma through suppression of the NF-κB pathway. Journal of biochemical and molecular toxicology. vol 31. issue 8. 2017-12-20. PMID:28346727. |
here, cell proliferation and apoptosis were detected by mtt and flow cytometry assay, respectively. |
2017-12-20 |
2023-08-13 |
Not clear |
| Raffaele Pezzani, Beatrice Rubin, Loris Bertazza, Marco Redaelli, Susi Barollo, Halenya Monticelli, Enke Baldini, Caterina Mian, Carla Mucignat, Carla Scaroni, Franco Mantero, Salvatore Ulisse, Maurizio Iacobone, Marco Boscar. The aurora kinase inhibitor VX-680 shows anti-cancer effects in primary metastatic cells and the SW13 cell line. Investigational new drugs. vol 34. issue 5. 2017-12-14. PMID:27177645. |
biomolecular and cellular tests were performed (such as mtt, thymidine assay, wright's staining, cell cycle and apoptosis analysis, western blot, qrt-pcr, and mutation analysis). |
2017-12-14 |
2023-08-13 |
Not clear |
| Bo Yang, XiaoLing Ni, LongXia Chen, Heng Zhang, PeiRong Ren, Yue Feng, Yue Chen, ShaoZhi Fu, JingBo W. Honokiol-loaded polymeric nanoparticles: an active targeting drug delivery system for the treatment of nasopharyngeal carcinoma. Drug delivery. vol 24. issue 1. 2017-12-12. PMID:28368206. |
mtt assay, cell uptake study and apoptosis test were assayed to detect the antitumor properties and targeting uptake by hne-1 cells in vitro. |
2017-12-12 |
2023-08-13 |
Not clear |
| Jinjiao He, Ziye Pan, Guiyou Tian, Xin Liu, Yunye Liu, Xiaochen Guo, Ying An, Liying Song, Hongsong Wu, Hongwei Cao, Dan Yu, Ruixiang Che, Pengfei Xu, Lubna M Rasoul, Deshan Li, Jiechao Yi. Newcastle disease virus chimeras expressing the Hemagglutinin- Neuraminidase protein of mesogenic strain exhibits an enhanced anti-hepatoma efficacy. Virus research. vol 221. 2017-12-11. PMID:27164362. |
furthermore, chimeras was shown to induce the cell apoptosis via mtt and annexin v-pi assays, reduce mitochondrial membrane potential and increase the mrna transcription level of caspase 3. |
2017-12-11 |
2023-08-13 |
mouse |
| N Yang, Y Liang, P Yang, T Yang, L Jian. Propofol inhibits lung cancer cell viability and induces cell apoptosis by upregulating microRNA-486 expression. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 50. issue 1. 2017-12-08. PMID:28076456. |
h1299 and/or h1792 cells were treated with or without propofol and transfected or not with mir-486 inhibitor, and then cell viability and apoptosis were analyzed by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) and flow cytometry. |
2017-12-08 |
2023-08-13 |
Not clear |
| Xiang Zhao, Rong He, Yu Liu, Yongkai Wu, Leitao Kan. UPregulated single-stranded DNA-binding protein 1 induces cell chemoresistance to cisplatin in lung cancer cell lines. Molecular and cellular biochemistry. vol 431. issue 1-2. 2017-12-04. PMID:28210897. |
next, the effects of ssdbp1 on cisplatin sensitivity, proliferation, and apoptosis of lung cancer cell lines were assayed by mtt and flow cytometry, respectively; abc transporters, apoptosis-related genes, and cell cycle-related genes by real-time pcr, and dna wound repair by comet assay. |
2017-12-04 |
2023-08-13 |
Not clear |