| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| W Zhang, Q He, L L Chan, F Zhou, M El Naghy, E B Thompson, N H Ansar. Involvement of caspases in 4-hydroxy-alkenal-induced apoptosis in human leukemic cells. Free radical biology & medicine. vol 30. issue 6. 2001-06-07. PMID:11295368. |
4-hydroxynonenal (hne), a reactive and cytotoxic end-product of lipid peroxidation, has been suggested to be a key mediator of oxidative stress-induced cell death and in various cell types has been shown to induce apoptosis. |
2001-06-07 |
2023-08-12 |
human |
| V Umansky, F Ratter, S Lampel, M Bucur, V Schirrmacher, A Ushmoro. Inhibition of nitric-oxide-mediated apoptosis in Jurkat leukemia cells despite cytochrome c release. Experimental cell research. vol 265. issue 2. 2001-06-07. PMID:11302692. |
moreover, an inhibitor of lipid peroxidation, trolox, suppressed apoptosis in jurkat cells induced by no donor glycerol trinitrate. |
2001-06-07 |
2023-08-12 |
human |
| T O Kishko, N P Dmitrenk. [Role of xanthine oxidase and xanthine dehydrogenase systems in thymocyte apoptosis, induced by papaverine]. Ukrains'kyi biokhimichnyi zhurnal (1999 ). vol 72. issue 3. 2001-03-22. PMID:11200484. |
during the process of developing thymocytes apoptosis caused by papaverine the reaction of lipid peroxidation was intensified. |
2001-03-22 |
2023-08-12 |
Not clear |
| F Zhang, L Zhou, F Huang, Y Liang, G Zhan. U-74389G suppresses lipid peroxidation and apoptosis following focal cerebral ischemia and reperfusion in rats. Chinese medical journal. vol 111. issue 9. 2001-03-01. PMID:11155678. |
u-74389g suppresses lipid peroxidation and apoptosis following focal cerebral ischemia and reperfusion in rats. |
2001-03-01 |
2023-08-12 |
rat |
| Z Y Chen, N W Istfa. Docosahexaenoic acid is a potent inducer of apoptosis in HT-29 colon cancer cells. Prostaglandins, leukotrienes, and essential fatty acids. vol 63. issue 5. 2001-02-15. PMID:11090257. |
in contrast, the dha-induced apoptosis is partially reversed by a synthetic antioxidant, butylated hydroxytoluene, indicating that lipid peroxidation may be involved in apoptotic signaling pathway induced by dha. |
2001-02-15 |
2023-08-12 |
Not clear |
| A V Rao, C Shah. Role of glutathione S-transferases in oxidative stress-induced male germ cell apoptosis. Free radical biology & medicine. vol 29. issue 10. 2001-02-02. PMID:11084290. |
if this increase in activity is inhibited with suitable inhibitors, the formation of products of lipid peroxidation is augmented, resulting in germ cell apoptosis. |
2001-02-02 |
2023-08-12 |
Not clear |
| A V Rao, C Shah. Role of glutathione S-transferases in oxidative stress-induced male germ cell apoptosis. Free radical biology & medicine. vol 29. issue 10. 2001-02-02. PMID:11084290. |
also, when constitutive gst activity is inhibited, accumulation of products of lipid peroxidation occurs, resulting in increased cellular apoptosis. |
2001-02-02 |
2023-08-12 |
Not clear |
| J F Kalinich, R Ramakrishnan, D E McClain, N Ramakrishna. 4-Hydroxynonenal, an end-product of lipid peroxidation, induces apoptosis in human leukemic T- and B-cell lines. Free radical research. vol 33. issue 4. 2001-02-01. PMID:11022844. |
4-hydroxynonenal, an end-product of lipid peroxidation, induces apoptosis in human leukemic t- and b-cell lines. |
2001-02-01 |
2023-08-12 |
human |
| J F Kalinich, R Ramakrishnan, D E McClain, N Ramakrishna. 4-Hydroxynonenal, an end-product of lipid peroxidation, induces apoptosis in human leukemic T- and B-cell lines. Free radical research. vol 33. issue 4. 2001-02-01. PMID:11022844. |
in our continuing studies on the role of membranes and lipid peroxidation in the induction of apoptosis, we investigated the effect of hne on cultured human malignant immune system cells. |
2001-02-01 |
2023-08-12 |
human |
| O Milhavet, H E McMahon, W Rachidi, N Nishida, S Katamine, A Mangé, M Arlotto, D Casanova, J Riondel, A Favier, S Lehman. Prion infection impairs the cellular response to oxidative stress. Proceedings of the National Academy of Sciences of the United States of America. vol 97. issue 25. 2001-01-18. PMID:11095725. |
in addition, the infected cells presented an increased lipid peroxidation and signs of apoptosis associated with a dramatic reduction in the activities of the glutathione-dependent and superoxide dismutase antioxidant systems. |
2001-01-18 |
2023-08-12 |
Not clear |
| P R Holden, N H James, A N Brooks, R A Roberts, I Kimber, W D Penni. Identification of a possible association between carbon tetrachloride-induced hepatotoxicity and interleukin-8 expression. Journal of biochemical and molecular toxicology. vol 14. issue 5. 2000-12-22. PMID:10970000. |
the changes induced by these compounds can vary from gross alterations in dna repair mechanisms, protein synthesis, and apoptosis, to more discrete changes in oxidative damage and lipid peroxidation. |
2000-12-22 |
2023-08-12 |
human |
| M Poljak-Blazi, M Kralj, M P Hadzija, N Zarković, K Zarković, G Wae. Involvement of lipid peroxidation, oncogene expression and induction of apoptosis in the antitumorous activity of ferric-sorbitol-citrate. Cancer biotherapy & radiopharmaceuticals. vol 15. issue 3. 2000-12-06. PMID:10941536. |
involvement of lipid peroxidation, oncogene expression and induction of apoptosis in the antitumorous activity of ferric-sorbitol-citrate. |
2000-12-06 |
2023-08-12 |
human |
| Y C Fu, X P Jin, S M Wei, H F Lin, S Kace. Ultraviolet radiation and reactive oxygen generation as inducers of keratinocyte apoptosis: protective role of tea polyphenols. Journal of toxicology and environmental health. Part A. vol 61. issue 3. 2000-11-30. PMID:11036506. |
studies were thus undertaken to investigate the effects of uva or reactive oxygen species (ros) on lipid peroxidation, cell cycle, and apoptosis in primary cultured rat keratinocytes and to determine the possible protective effects of tea polyphenols (tpp). |
2000-11-30 |
2023-08-12 |
rat |
| Y C Fu, X P Jin, S M Wei, H F Lin, S Kace. Ultraviolet radiation and reactive oxygen generation as inducers of keratinocyte apoptosis: protective role of tea polyphenols. Journal of toxicology and environmental health. Part A. vol 61. issue 3. 2000-11-30. PMID:11036506. |
in summary, these data demonstrated that uva damage to skin keratinocytes in vitro was similar to that for ros and that tpp protects against uva-induced cytotoxicity by inhibiting lipid peroxidation and apoptosis. |
2000-11-30 |
2023-08-12 |
rat |
| b' M MacCarrone, G Van Zadelhoff, G A Veldink, J F Vliegenthart, A Finazzi-Agr\\xc3\\xb. Early activation of lipoxygenase in lentil (Lens culinaris) root protoplasts by oxidative stress induces programmed cell death. European journal of biochemistry. vol 267. issue 16. 2000-10-18. PMID:10931190.' |
the commitment of cells to apoptosis caused by h2o2 was characterized by an early increase of lipoxygenase activity, of ultraweak luminescence and of membrane lipid peroxidation, which reached 720, 350 and 300% of controls, respectively, at 6 h after h2o2 treatment. |
2000-10-18 |
2023-08-12 |
Not clear |
| Y Soh, K S Jeong, I J Lee, M A Bae, Y C Kim, B J Son. Selective activation of the c-Jun N-terminal protein kinase pathway during 4-hydroxynonenal-induced apoptosis of PC12 cells. Molecular pharmacology. vol 58. issue 3. 2000-09-25. PMID:10953046. |
the by-product of lipid peroxidation, 4-hydroxynonenal (hne), was shown to cause apoptosis in pc12 cells. |
2000-09-25 |
2023-08-12 |
Not clear |
| S J Stohs, D Bagchi, E Hassoun, M Bagch. Oxidative mechanisms in the toxicity of chromium and cadmium ions. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. vol 19. issue 3. 2000-09-14. PMID:10983887. |
these reactive oxygen species result in increased lipid peroxidation, enhanced excretion of urinary lipid metabolites, modulation of intracellular oxidized states, dna damage, membrane damage, altered gene expression, and apoptosis. |
2000-09-14 |
2023-08-12 |
Not clear |
| T Böhler, J Waiser, H Hepburn, J Gaedeke, C Lehmann, P Hambach, K Budde, H H Neumaye. TNF-alpha and IL-1alpha induce apoptosis in subconfluent rat mesangial cells. Evidence for the involvement of hydrogen peroxide and lipid peroxidation as second messengers. Cytokine. vol 12. issue 7. 2000-09-08. PMID:10880243. |
coincubation with catalase inhibited tnf-alpha and il-1alpha induced apoptosis as well as lipid peroxidation. |
2000-09-08 |
2023-08-12 |
rat |
| T Böhler, J Waiser, H Hepburn, J Gaedeke, C Lehmann, P Hambach, K Budde, H H Neumaye. TNF-alpha and IL-1alpha induce apoptosis in subconfluent rat mesangial cells. Evidence for the involvement of hydrogen peroxide and lipid peroxidation as second messengers. Cytokine. vol 12. issue 7. 2000-09-08. PMID:10880243. |
these results provide evidence that tnf-alpha and il-1alpha induce apoptosis in rat mc with hydrogen peroxide and lipid peroxidation as second messengers. |
2000-09-08 |
2023-08-12 |
rat |
| Y H Lee, S Y Kim, J R Kim, K T Yoh, S H Baek, M J Kim, S H Ryu, P G Suh, J H Ki. Overexpression of phospholipase Cbeta-1 protects NIH3T3 cells from oxidative stress-induced cell death. Life sciences. vol 67. issue 7. 2000-09-07. PMID:10968412. |
oxidative stress has been implicated in a wide range of cellular damage which includes dna oxidation, membrane lipid peroxidation, and apoptosis. |
2000-09-07 |
2023-08-12 |
Not clear |