| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Velez-Pardo, M Jimenez Del Rio, H Verschueren, G Ebinger, G Vauqueli. Dopamine and iron induce apoptosis in PC12 cells. Pharmacology & toxicology. vol 80. issue 2. 1997-05-09. PMID:9060038. |
however, there is no necessary casual link between lipid peroxidation and apoptosis. |
1997-05-09 |
2023-08-12 |
rat |
| P Whittaker, F A Hines, M G Robl, V C Dunke. Histopathological evaluation of liver, pancreas, spleen, and heart from iron-overloaded Sprague-Dawley rats. Toxicologic pathology. vol 24. issue 5. 1997-03-07. PMID:8923676. |
the toxic effects of fe overload in this rat model include cellular apoptosis or necrosis in heart, spleen, and pancreas and, when coupled with the findings on lipid peroxidation, suggests that oxidative stress is involved in the pathogenesis of the lesions. |
1997-03-07 |
2023-08-12 |
rat |
| T Patel, G J Gore. Inhibition of bile-salt-induced hepatocyte apoptosis by the antioxidant lazaroid U83836E. Toxicology and applied pharmacology. vol 142. issue 1. 1997-02-24. PMID:9007040. |
gcdc-induced apoptosis was associated with lipid peroxidation as demonstrated by an increase in 8-isoprostane release. |
1997-02-24 |
2023-08-12 |
rat |
| T Patel, G J Gore. Inhibition of bile-salt-induced hepatocyte apoptosis by the antioxidant lazaroid U83836E. Toxicology and applied pharmacology. vol 142. issue 1. 1997-02-24. PMID:9007040. |
in summary, during treatment of hepatocytes with gcdc, (1) apoptosis is associated with lipid peroxidation, and (2) the antioxidant lazaroid u83836e inhibits both lipid peroxidation and apoptosis. |
1997-02-24 |
2023-08-12 |
rat |
| E Masliah, N Ge, L Muck. Pathogenesis of HIV-1 associated neurodegeneration. Critical reviews in neurobiology. vol 10. issue 1. 1997-01-03. PMID:8853954. |
derangements of the neuronal calcium homeostasis, lipid peroxidation, and induction of programmed cell death (apoptosis) may all play a role as final common pathogenetic pathways in hiv-1-induced neurodegeneration. |
1997-01-03 |
2023-08-12 |
mouse |
| J Lotem, M Peled-Kamar, Y Groner, L Sach. Cellular oxidative stress and the control of apoptosis by wild-type p53, cytotoxic compounds, and cytokines. Proceedings of the National Academy of Sciences of the United States of America. vol 93. issue 17. 1996-10-31. PMID:8799172. |
induction of apoptosis by wild-type p53 was not preceded by increased peroxide production or lipid peroxidation and the protective effect of cytokines was not associated with a decrease in these properties. |
1996-10-31 |
2023-08-12 |
Not clear |
| L Li, R F Hamilton, A Kirichenko, A Holia. 4-Hydroxynonenal-induced cell death in murine alveolar macrophages. Toxicology and applied pharmacology. vol 139. issue 1. 1996-08-21. PMID:8685896. |
our observation that a product of lipid peroxidation causes apoptosis suggested that it might be a mediator for oxidative stress-induced apoptosis. |
1996-08-21 |
2023-08-12 |
mouse |
| E Nishio, S Arimura, Y Watanab. Oxidized LDL induces apoptosis in cultured smooth muscle cells: a possible role for 7-ketocholesterol. Biochemical and biophysical research communications. vol 223. issue 2. 1996-08-08. PMID:8670295. |
we conclude that ox-ldl induces apoptosis in smcs and that this apoptosis contributes to lipid peroxidation. |
1996-08-08 |
2023-08-12 |
Not clear |
| N Ramakrishnan, J F Kalinich, D E McClai. Ebselen inhibition of apoptosis by reduction of peroxides. Biochemical pharmacology. vol 51. issue 11. 1996-06-24. PMID:8630085. |
peroxide generation and membrane lipid peroxidation preceded both internucleosomal dna fragmentation and morphological changes characteristic of apoptosis. |
1996-06-24 |
2023-08-12 |
mouse |
| N Ramakrishnan, J F Kalinich, D E McClai. Ebselen inhibition of apoptosis by reduction of peroxides. Biochemical pharmacology. vol 51. issue 11. 1996-06-24. PMID:8630085. |
the results suggest that peroxide generation and membrane lipid peroxidation may be important signaling events that trigger apoptosis in irradiated cells. |
1996-06-24 |
2023-08-12 |
mouse |
| T Sakamoto, W T Repasky, K Uchida, A Hirata, F Hirat. Modulation of cell death pathways to apoptosis and necrosis of H2O2-treated rat thymocytes by lipocortin I. Biochemical and biophysical research communications. vol 220. issue 3. 1996-05-20. PMID:8607818. |
available evidence suggests that lipocortin i modulates signals for cell death pathways of h2o2-treated rat thymocytes to apoptosis and necrosis by regulating cellular phospholipase a2 activities but not by inhibiting membrane lipid peroxidation. |
1996-05-20 |
2023-08-12 |
rat |
| M Peled-Kamar, J Lotem, E Okon, L Sachs, Y Grone. Thymic abnormalities and enhanced apoptosis of thymocytes and bone marrow cells in transgenic mice overexpressing Cu/Zn-superoxide dismutase: implications for Down syndrome. The EMBO journal. vol 14. issue 20. 1995-12-21. PMID:7588627. |
this higher susceptibility to lps-induced apoptosis was associated with an increased production of hydrogen peroxide and a higher degree of lipid peroxidation. |
1995-12-21 |
2023-08-12 |
mouse |
| L K Yacoub, F Fogt, B Griniuviene, A A Nanj. Apoptosis and bcl-2 protein expression in experimental alcoholic liver disease in the rat. Alcoholism, clinical and experimental research. vol 19. issue 4. 1995-12-18. PMID:7485830. |
we used the intragastric feeding rat model to investigate the relationship between severity of alcoholic liver injury, apoptosis, bcl-2 protein expression, and lipid peroxidation. |
1995-12-18 |
2023-08-12 |
rat |
| P A Sandstrom, D Pardi, P W Tebbey, R W Dudek, D M Terrian, T M Folks, T M Buttk. Lipid hydroperoxide-induced apoptosis: lack of inhibition by Bcl-2 over-expression. FEBS letters. vol 365. issue 1. 1995-07-10. PMID:7774717. |
increased membrane lipid peroxidation has recently been implicated as being associated with apoptosis. |
1995-07-10 |
2023-08-12 |
Not clear |
| J M McCor. Superoxide radical: controversies, contradictions, and paradoxes. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). vol 209. issue 2. 1995-07-06. PMID:7770461. |
several examples of the radical's schizophrenic behavior include its roles in bactericidal action versus inflammation, as a modulator of cell division versus malignant transformation and apoptosis, and as both an initiator and a terminator of lipid peroxidation. |
1995-07-06 |
2023-08-12 |
Not clear |
| S Haldar, N Jena, C M Croc. Inactivation of Bcl-2 by phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. vol 92. issue 10. 1995-06-16. PMID:7753834. |
in addition, phosphorylated bcl-2 can no longer prevent lipid peroxidation as required to protect cells from apoptosis. |
1995-06-16 |
2023-08-12 |
Not clear |
| V S Posokhov, O A Rozenberg, K P Khanso. [Modification of radiation sensitivity of lymphocytes of the rat thymus gland using cholesterol-enriched autoliposomes]. Biulleten' eksperimental'noi biologii i meditsiny. vol 113. issue 2. 1992-07-27. PMID:1611053. |
it was found that in the modified cells the processes of lipid peroxidation, enzymatic degradation of chromatin and apoptosis are inhibited. |
1992-07-27 |
2023-08-11 |
rat |