Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Jian Chen, Qiyu Zhan, Lie Li, Simin Xi, Longmei Cai, Ruiyuan Liu, Lujia Che. Cell-membrane targeting sonodynamic therapy combination with FSP1 inhibition for ferroptosis-boosted immunotherapy. Materials today. Bio. vol 30. 2025-01-15. PMID:39811609. |
tif nps could induce a sonodynamic effect, which promotes lipid peroxidation and drives apoptosis. |
2025-01-15 |
2025-01-17 |
Not clear |
Rehab M Abdel-Megeed, Abdel-Hamid Z Abdel-Hamid, Mai O Kadr. Titanium nanostructure mitigating doxorubicin-induced testicular toxicity in rats via regulating major autophagy signaling pathways. Toxicology reports. vol 14. 2025-01-15. PMID:39811821. |
oxidative stress, lipid peroxidation and apoptosis in germ cells as well as low sperm count, motility and disturbing steroidogenesis are the principal machineries of dox-induced testicular toxicity. |
2025-01-15 |
2025-01-17 |
rat |
Çağla Zübeyde Köprü, Burcu Baba, Dilek Yona. Zerumbone Induces Apoptosis in Non-Small-Cell Lung Cancer via Biomolecular Alterations: A Microscopic and Spectroscopic Study. Journal of biophotonics. 2025-01-14. PMID:39807038. |
this study aimed to evaluate the effect of zerumbone on cell viability by wst-1 test, apoptosis by tunel, lipid peroxidation markers (malondialdehyde, mda, and 4-hydroxynonenal, hne) by using assay kits, and biomolecular changes by atr-ftir spectroscopy in a549 cells. |
2025-01-14 |
2025-01-16 |
Not clear |
Çağla Zübeyde Köprü, Burcu Baba, Dilek Yona. Zerumbone Induces Apoptosis in Non-Small-Cell Lung Cancer via Biomolecular Alterations: A Microscopic and Spectroscopic Study. Journal of biophotonics. 2025-01-14. PMID:39807038. |
consequently, zerumbone-induced apoptosis was accompanied by increased aldehyde products during lipid peroxidation as well as biomolecular alterations. |
2025-01-14 |
2025-01-16 |
Not clear |
Xinrui Yang, Jing Liu, Yaru Yin, Luxun Yang, Mingquan Gao, Zifei Wu, Binghui Lu, Shenglin Luo, Weidong Wang, Rong L. MSC-EXs inhibits uranium nephrotoxicity by competitively binding key proteins and inhibiting ROS production. Ecotoxicology and environmental safety. vol 289. 2025-01-10. PMID:39793287. |
this regulation leads to a reduction in mitochondrial ros production, alleviates lipid peroxidation, and consequently decreases cellular apoptosis and ferroptosis. |
2025-01-10 |
2025-01-14 |
mouse |
Sheng-Yow Ho, Chia-Hui Lin, Chien-Cheng Huang, Cheng-Hsien Lin, Mao-Tsun Lin, Ying-Jan Wang, Jui-Ti Ma, Li-Tsun Shieh, Ching-Ping Chang, Hung-Jung Li. Hyperbaric oxygen therapy attenuates brain radiation-induced cognitive deficits in rats. International journal of medical sciences. vol 22. issue 2. 2025-01-09. PMID:39781518. |
behavioral tests and histochemical analyses were conducted four weeks post-wbrt to assess cognitive function, hippocampal microgliosis, apoptosis, and lipid peroxidation. |
2025-01-09 |
2025-01-13 |
rat |
Sheng-Yow Ho, Chia-Hui Lin, Chien-Cheng Huang, Cheng-Hsien Lin, Mao-Tsun Lin, Ying-Jan Wang, Jui-Ti Ma, Li-Tsun Shieh, Ching-Ping Chang, Hung-Jung Li. Hyperbaric oxygen therapy attenuates brain radiation-induced cognitive deficits in rats. International journal of medical sciences. vol 22. issue 2. 2025-01-09. PMID:39781518. |
compared with the rats with 0 gy wbrt on 28 days, the rats with 10 gy wbrt on 28 days had significantly higher severity of spatial learning and memory dysfunction and hippocampal microgliosis, newborn neuronal apoptosis, and lipid peroxidation. |
2025-01-09 |
2025-01-13 |
rat |
Sheng-Yow Ho, Chia-Hui Lin, Chien-Cheng Huang, Cheng-Hsien Lin, Mao-Tsun Lin, Ying-Jan Wang, Jui-Ti Ma, Li-Tsun Shieh, Ching-Ping Chang, Hung-Jung Li. Hyperbaric oxygen therapy attenuates brain radiation-induced cognitive deficits in rats. International journal of medical sciences. vol 22. issue 2. 2025-01-09. PMID:39781518. |
hbot significantly prevented and reversed wbrt-induced cognitive deficits, hippocampal microgliosis, newborn neuronal apoptosis, and lipid peroxidation. |
2025-01-09 |
2025-01-13 |
rat |
Sheng-Yow Ho, Chia-Hui Lin, Chien-Cheng Huang, Cheng-Hsien Lin, Mao-Tsun Lin, Ying-Jan Wang, Jui-Ti Ma, Li-Tsun Shieh, Ching-Ping Chang, Hung-Jung Li. Hyperbaric oxygen therapy attenuates brain radiation-induced cognitive deficits in rats. International journal of medical sciences. vol 22. issue 2. 2025-01-09. PMID:39781518. |
the findings suggest that wbrt disrupts neurogenesis and enhance microgliosis, apoptosis of neuronal progenitors, and lipid peroxidation in the dentate gyrus, potentially leading to cognitive deficits and neuronal death. |
2025-01-09 |
2025-01-13 |
rat |
Zheng Wang, Zhixiang Zhang, Yunhui Yue, Yifan Hou, Yujia Cao, Changsheng Guo, Xiaobo Nie, Junqing Ho. Crosstalk between WNT signaling and ferroptosis in cancer. Molecular cancer research : MCR. 2025-01-09. PMID:39786453. |
ferroptosis, a unique iron-dependent form of cell death that is distinct from apoptosis, is driven by lipid peroxidation and excessive reactive oxygen species (ros) production. |
2025-01-09 |
2025-01-13 |
Not clear |
Petros Fountoulakis, Islam Kourampi, Panagiotis Theofilis, Anastasios Marathonitis, Georgios Angelos Papamikroulis, Ourania Katsarou, Georgios Marinos, Evangelos Oikonomou, Gerasimos Siasos, Dimitris Tousouli. Oxidative Stress Biomarkers in Hypertension. Current medicinal chemistry. 2025-01-06. PMID:39757687. |
salucin-β-induced activation of angiotensin-ii and nadph results in vascular remodeling and fibrosis, while lipid peroxidation and parp- 1 activation further exacerbate cellular apoptosis and vascular calcification. |
2025-01-06 |
2025-01-08 |
Not clear |
Fatemeh Vandvali, Hossein Daghigh Kia, Abouzar Najafi, Hamid Reza Rafieian-Naeini, Woo Kyun Ki. Improving rooster semen cryopreservation with telmisartan-enhanced extender. Poultry science. vol 104. issue 2. 2024-12-31. PMID:39740494. |
the study concludes that telmisartan, at an optimal concentration of 15 µg/ml, enhances the cryopreservation outcomes for rooster semen by improving motility, mitochondrial function, and antioxidant defense while reducing lipid peroxidation and apoptosis. |
2024-12-31 |
2025-01-03 |
chicken |
Bei Chen, Shuilin Cai, Lulu Cui, Ting Yu, Kun Qiao, Yongchang Su, Min Xu, Haiyan Tang, Shuji Liu, Ming Yang, Zhiyu Li. Novel peptide inhibitor of matrix Metalloproteinases-1 from pufferfish skin collagen hydrolysates and its potential Photoprotective activity via the MAPK/AP-1 signaling pathway. Journal of photochemistry and photobiology. B, Biology. vol 262. 2024-12-28. PMID:39732112. |
exposure of zebrafish to 25-100 μm gp8 effectively mitigated uvb-induced damage, restoring up to 31.2 % of caudal fin integrity, while significantly reducing ros levels, lipid peroxidation, and cellular apoptosis. |
2024-12-28 |
2024-12-31 |
zebrafish |
Ruolin Wu, Xiaole Wang, Jingwen Zhang, Chengbo Lu, Bing Li, Zhongkun Du, Jun Wang, Jinhua Wang, Yue Yang, Lusheng Zh. Lower toxicity of HFPO-DA compared to its predecessor PFOA to the earthworm Eisenia fetida: Evidence from oxidative stress and transcriptomic analysis. Journal of hazardous materials. vol 486. 2024-12-26. PMID:39724713. |
our findings revealed that both hfpo-da and pfoa caused oxidative damage, apoptosis, reproductive disorders, and neurotoxicity in e. fetida at a concentration of 0.2 mg/kg following exposure for 28 d. specifically, at the molecular level, pfoa resulted in a significant decline in total antioxidant capacity and lipid peroxidation, whereas hfpo-da did not have the same effect. |
2024-12-26 |
2024-12-29 |
Not clear |
Dipa Kusi, Yan Sun, Chenguang Li. Advances in Manganese-based nanomaterials for cancer therapy via regulating Non-Ferrous ferroptosis. International journal of pharmaceutics. 2024-12-20. PMID:39706379. |
ferroptosis, a regulated form of cell death distinct from apoptosis, was first identified in 2012 and is characterized by iron-dependent lipid peroxidation driven by reactive oxygen species (ros). |
2024-12-20 |
2024-12-24 |
Not clear |
Hui-Ping Xiao, Man-Yi Du, Xian-Bin Sun, Ruo-Fei Xu, Dong-Miao Li, Sheng-Nan Yue, Ping-Wei Cai, Rong-Zhi Sun, Zi-Zhong Zhang, Xing Huang, Xin-Xiong Li, Yu Gao, Shou-Tian Zhen. A Highly Biocompatible Polyoxotungstate with Fenton-like Reaction Activity for Potent Chemodynamic Therapy of Tumors. Angewandte Chemie (International ed. in English). 2024-12-16. PMID:39679939. |
further biomedical studies reveal that 1 can trigger cell apoptosis and promote lipid peroxidation, exhibiting high cytotoxicity and selectivity towards b16-f10 mouse melanoma cancer cells with an ic50 value of 4.75 μm. |
2024-12-16 |
2024-12-21 |
mouse |
Akash Chatterjee, Joyanta Mondal, Subhojit Paul, Himangshu Sharma, Rajib Kumar Goswami, Prosenjit Se. Deciphering the Comprehensive Structure-Activity Relationship of Sunshinamide for Breast Cancer Therapy through Dual Modulation of Apoptotic and Ferroptotic Pathways via TrxR1 and Gpx4 Inhibition. Journal of medicinal chemistry. 2024-12-12. PMID:39668144. |
our recent findings unveil that sunshinamide targets trxr1, leading to ros generation and er-stress-mediated apoptosis, while also promoting lipid peroxidation by targeting gpx4, rendering cancer cells vulnerable to ferroptosis. |
2024-12-12 |
2024-12-22 |
Not clear |
Zhanrui Zhang, Hongyu Liu, Jun Che. [Role of Mitochondria in Ferroptosis and Its Relationship to Tumors]. Zhongguo fei ai za zhi = Chinese journal of lung cancer. vol 27. issue 10. 2024-12-04. PMID:39631835. |
ferroptosis is a recently discovered form of cell death that is distinct from apoptosis, characterized primarily by the accumulation of intracellular iron and increased levels of lipid peroxidation. |
2024-12-04 |
2024-12-07 |
Not clear |
Asmaa R Mohamed, Nagui H Fares, Yomna I Mahmou. Morin Ameliorates Lipopolysaccharides-Induced Sepsis-Associated Encephalopathy and Cognitive Impairment in Albino Mice. Neurochemical research. vol 50. issue 1. 2024-11-16. PMID:39549093. |
this was accompanied with the augmentation of the total antioxidant capacity, as well as the suppression of tissue levels of the lipid peroxidation marker malondialdehyde, apoptosis (cleaved-caspase-3), glial fibrillary acidic protein, and the proinflammatory cytokine tumor necrosis factor. |
2024-11-16 |
2024-11-20 |
mouse |
Mohammed Eleyan, Mohammed R Zughbur, Mohamed Hussien, Basim M Ayesh, Khairy A Ibrahi. Carvacrol modulates antioxidant enzymes, DNA integrity, and apoptotic markers in zearalenone-exposed fetal rat liver. Drug and chemical toxicology. 2024-11-13. PMID:39538112. |
surprisingly, co-treatment with crv significantly mitigated fetal hepatic lipid peroxidation, antioxidant disturbance, apoptosis, and dna damage after maternal exposure to zea. |
2024-11-13 |
2024-11-17 |
rat |