| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Karthikeyan Kandaswamy, Ajay Guru, Siva Prasad Panda, Anahas Perianaika Matharasi Antonyraj, Zulhisyam Abdul Kari, Jayant Giri, Bader O Almutairi, Selvaraj Arokiyaraj, Guilherme Malafaia, Jesu Arockiara. Polystyrene nanoplastics synergistically exacerbate diclofenac toxicity in embryonic development and the health of adult zebrafish. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2024-04-19. PMID:38641085. |
furthermore, we noted that larvae exposed to combined pollutants showed a higher frequency of morphological abnormalities and increased oxidative stress, apoptosis, and lipid peroxidation. |
2024-04-19 |
2024-04-22 |
zebrafish |
| Joshua Schustak, Hongwei Han, Kyle Bond, Qian Huang, Magali Saint-Geniez, Yi Ba. Phenotypic high-throughput screening identifies aryl hydrocarbon receptor agonism as common inhibitor of toxin-induced retinal pigment epithelium cell death. PloS one. vol 19. issue 4. 2024-04-18. PMID:38635505. |
we show that the metabolic by-product of the visual cycle all-trans-retinal (atral) induces rpe apoptosis, while the lipid peroxidation by-product 4-hydroxynonenal (4-hne) promotes necrotic cell death. |
2024-04-18 |
2024-04-21 |
human |
| Yan Huang, Guowei Liu, Fangmei Zheng, Jianling Chen, Youyu Lin, Junwei Wang, Yide Huang, Yiru Pen. Asymmetric silicon phthalocyanine based nanoparticle with spatiotemporally targeting of mitochondria for synergistic apoptosis-ferroptosis antitumor treatment. Colloids and surfaces. B, Biointerfaces. vol 238. 2024-04-12. PMID:38608462. |
a promising therapeutic strategy in cancer treatment merges photodynamic therapy (pdt) induced apoptosis with ferroptosis, a form of programmed cell death governed by iron-dependent lipid peroxidation. |
2024-04-12 |
2024-04-15 |
Not clear |
| Jun Yang, Caihong Yan, Shaolin Chen, Min Li, Yanmei Miao, Xinglong Ma, Junfa Zeng, Peng Xi. The possible mechanisms of ferroptosis in sepsis-associated acquired weakness. Frontiers in physiology. vol 15. 2024-04-11. PMID:38601213. |
unlike other forms of cell death such as autophagy, apoptosis, and necrosis, ferroptosis is primarily driven by lipid peroxidation. |
2024-04-11 |
2024-04-13 |
Not clear |
| Ze Wang, Xiaojun Ren, Yunfeng Li, Ling Qiu, Dongzhou Wang, Annan Liu, Hao Liang, Lei Li, Bai Yang, Andrew K Whittaker, Zhongshan Liu, Shunzi Jin, Quan Lin, Tiejun Wan. Reactive Oxygen Species Amplifier for Apoptosis-Ferroptosis Mediated High-Efficiency Radiosensitization of Tumors. ACS nano. 2024-04-01. PMID:38556985. |
large amounts of ros and ionizing radiation further lead to apoptosis by increasing dna damage, and ferroptosis by enhancing lipid peroxidation, significantly improving the therapeutic efficiency of rt. |
2024-04-01 |
2024-04-04 |
Not clear |
| Xiaoyu Luan, Peng Chen, Longyu Miao, Xinying Yuan, Chaoqun Yu, Guohu D. Ferroptosis in organ ischemia-reperfusion injuries: recent advancements and strategies. Molecular and cellular biochemistry. 2024-03-31. PMID:38556592. |
different from other classical cell death programs such as necrosis and apoptosis, ferroptosis involving iron-catalyzed lipid peroxidation is characterized by fe |
2024-03-31 |
2024-04-03 |
Not clear |
| Haodong Zhang, Jian X. Unveiling thioacetamide-induced toxicity: Multi-organ damage and omitted bone toxicity. Human & experimental toxicology. vol 43. 2024-03-26. PMID:38531387. |
the principal pathological consequences arising from taa exposure encompass oxidative stress, inflammation, lipid peroxidation, fibrosis, apoptosis induction, dna damage, and osteoclast formation. |
2024-03-26 |
2024-03-29 |
Not clear |
| Katarzyna Mokra, Izabela Kaczmarska, Bożena Bukowsk. Perfluorooctane sulfonate (PFOS) and its selected analogs induce various cell death types in peripheral blood mononuclear cells. Chemosphere. 2024-03-14. PMID:38485001. |
pbmcs were exposed to pfos, pfbs and pfhxs at concentrations ranging from 0.02 to 400 μm for 24 h, they were then tested for viability, apoptosis (changes in cytosolic calcium ions level and caspase-3, -8 and -9 activation), ferroptosis (changes in chelatable iron ions level and lipid peroxidation), and autophagy (lc3-ii and raptor level assay). |
2024-03-14 |
2024-03-17 |
human |
| Yina Li, Yujin Gao, Dan Yao, Zongshuai Li, Jiamian Wang, Xijun Zhang, Xingxu Zhao, Yong Zhan. Heme Oxygenase-1 Regulates Zearalenone-Induced Oxidative Stress and Apoptosis in Sheep Follicular Granulosa Cells. International journal of molecular sciences. vol 25. issue 5. 2024-03-13. PMID:38473826. |
treating primary sheep follicular granulosa cells with different concentrations of zea promoted the overproduction of reactive oxygen species (ros), increased lipid peroxidation products, led to cellular oxidative stress, decreased antioxidant enzyme activities, and induced cell apoptosis. |
2024-03-13 |
2024-03-15 |
Not clear |
| Cristina Palacin-Martinez, Luis Anel-Lopez, Mercedes Alvarez, Marta Neila-Montero, Rafael Montes-Garrido, Cristina Soriano-Úbeda, Paulino de Paz, Luis Anel, Marta F Riesc. The characterization of CellROX™ probes could be a crucial factor in ram sperm quality assessment. Frontiers in veterinary science. vol 11. 2024-03-13. PMID:38476170. |
sperm analyses, including viability, apoptosis, lipid peroxidation, motility and kinetic parameters, were applied to compare several experimental groups with different sperm qualities. |
2024-03-13 |
2024-03-15 |
Not clear |
| Huiming Zhang, Naifeng Chen, Chenglong Ding, Huinan Zhang, Dejiang Liu, Shuang Li. Ferroptosis and EMT resistance in cancer: a comprehensive review of the interplay. Frontiers in oncology. vol 14. 2024-03-12. PMID:38469234. |
ferroptosis differs from traditional cell death mechanisms like apoptosis, necrosis, and autophagy, primarily due to its reliance on iron metabolism and the loss of glutathione peroxidase activity, leading to lipid peroxidation and cell death. |
2024-03-12 |
2024-03-14 |
Not clear |
| Lvlan Ye, Xiangqiong Wen, Jiale Qin, Xiang Zhang, Youpeng Wang, Ziyang Wang, Ti Zhou, Yuqin Di, Weiling H. Metabolism-regulated ferroptosis in cancer progression and therapy. Cell death & disease. vol 15. issue 3. 2024-03-08. PMID:38459004. |
ferroptosis is a regulated cell death induced by iron-dependent lipid peroxidation, which is morphologically different from apoptosis, necrosis, necroptosis, pyroptosis, autophagy-dependent cell death and cuprotosis. |
2024-03-08 |
2024-03-11 |
Not clear |
| Agata Tomaszewska, Weronika Gonciarz, Tomasz Rechcinski, Magdalena Chmiela, Anna K Kurdowska, Agnieszka Krup. Helicobacter pylori components increase the severity of metabolic syndrome and its hepatic manifestations induced by a high fat diet. Scientific reports. vol 14. issue 1. 2024-03-08. PMID:38459219. |
our results showed that hp infection in animals exposed to a high-fat diet increased oxidative stress and lipid peroxidation, followed by endothelial lipid deposition, impaired endothelial apoptosis, cell lysis, and increased vascular stiffness. |
2024-03-08 |
2024-03-11 |
Not clear |
| Hanieh Ghasemian Nafchi, Yaser Azizi, Iman Halvae. Effect of Conditioned Medium from Human Adipose-Derived Mesenchymal Stem Cells on Human Sperm Quality During Cryopreservation. Reproductive sciences (Thousand Oaks, Calif.). 2024-03-06. PMID:38448740. |
sperm motility, viability, morphology, apoptosis, mitochondrial potential, and lipid peroxidation, and dna fragmentation were evaluated before freezing and after thawing. |
2024-03-06 |
2024-03-09 |
human |
| Ziyi Liu, Hanbing Zhang, Guodong Hong, Xiuli Bi, Jun Hu, Tiancheng Zhang, Yachun An, Na Guo, Fengyue Dong, Yu Xiao, Wen Li, Xiaoxu Zhao, Bo Chu, Siwei Guo, Xiaohan Zhang, Renjie Chai, Xiaolong F. Inhibition of Gpx4-mediated Ferroptosis Alleviates Cisplatin-Induced Hearing Loss in C57BL/6 mice. Molecular therapy : the journal of the American Society of Gene Therapy. 2024-02-28. PMID:38414247. |
cisplatin-induced ototoxicity is mainly associated with the production of reactive oxygen species, activation of apoptosis, and accumulation of intracellular lipid peroxidation, which also is involved in ferroptosis induction. |
2024-02-28 |
2024-03-01 |
mouse |
| Santosh Pushpa Ramya Ranjan Nayak, Catharine Basty, Seenivasan Boopathi, Loganathan Sumathi Dhivya, Khaloud Mohammed Alarjani, Mohamed Ragab Abdel Gawwad, Raghda Hager, Muthu Kumaradoss Kathiravan, Jesu Arockiara. Furan-based Chalcone Annihilates the Multi-Drug-Resistant Pseudomonas aeruginosa and Protects Zebra Fish Against its Infection. Journal of microbiology (Seoul, Korea). 2024-02-22. PMID:38383881. |
dko1 effectively shielded against p. aeruginosa-induced inflammation, oxidative stress, lipid peroxidation, and apoptosis in zebrafish larvae. |
2024-02-22 |
2024-02-24 |
cat |
| Aline Yammine, Imen Ghzaiel, Vivien Pires, Amira Zarrouk, Omar Kharoubi, Hélène Greige-Gerges, Lizette Auezova, Gérard Lizard, Anne Veju. Cytoprotective effects of α-linolenic acid, eicosapentaenoic acid, docosahexaenoic acid, oleic acid and α-tocopherol on 7-ketocholesterol - Induced oxiapoptophagy: Major roles of PI3-K / PDK-1 / Akt signaling pathway and glutathione peroxidase activity in cell rescue. Current research in toxicology. vol 6. 2024-02-21. PMID:38379847. |
on murine n2a cells, 7-ketocholesterol induced an oxiapotophagic mode of cell death characterized by oxidative stress (reactive oxygen species overproduction on whole cells and at the mitochondrial level; lipid peroxidation), apoptosis induction (caspase-9, -3 and -7 cleavage, parp degradation) and autophagy (increased ratio lc3-ii / lc3-i). |
2024-02-21 |
2024-02-23 |
Not clear |
| Qi Lu, Xing Qin, Chu Chen, Wei Yu, Jie Lin, Xiaoyu Liu, Rui Guo, Russel J Reiter, Milad Ashrafizadeh, Ming Yuan, Jun Re. Elevated levels of alcohol dehydrogenase aggravate ethanol-evoked cardiac remodeling and contractile anomalies through FKBP5-yap-mediated regulation of ferroptosis and ER stress. Life sciences. 2024-02-21. PMID:38382873. |
in vitro study revealed that the ethanol metabolite acetaldehyde evoked cardiac contractile anomalies, lipid peroxidation, and apoptosis, the effects of which were mitigated by alda-1, inhibition of er stress, fkbp5 and yap. |
2024-02-21 |
2024-02-24 |
mouse |
| Weixue Wang, Tongtong Wang, Yan Zhang, Ting Deng, Haiyang Zhang, Y I B. Gastric cancer secreted miR-214-3p inhibits the anti-angiogenesis effect of apatinib by suppressing ferroptosis in vascular endothelial cells. Oncology research. vol 32. issue 3. 2024-02-19. PMID:38370339. |
different from necrosis, apoptosis, autophagy and other forms of cell death, ferroptosis is a mechanism that catalyzes lipid peroxidation of polyunsaturated fatty acids under the action of iron divalent or lipoxygenase, leading to cell death. |
2024-02-19 |
2024-02-21 |
Not clear |
| Ge Song, Minghui Li, Shumin Fan, Mengmeng Qin, Bin Shao, Wenbing Dai, Hua Zhang, Xueqing Wang, Bing He, Qiang Zhan. Boosting synergism of chemo- and immuno-therapies Acta pharmaceutica Sinica. B. vol 14. issue 2. 2024-02-07. PMID:38322346. |
differing from the paclitaxel-induced apoptosis, the involvement of alendronate inhibits the mevalonate metabolism, changes the mitochondrial morphology, disturbs the redox homeostasis, and causes the accumulation of mitochondrial ros and lethal lipid peroxides (lpo). |
2024-02-07 |
2024-02-09 |
Not clear |