| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Junqi Men, Li Zhang, Ruiyun Peng, Yanyang Li, Meng Li, Hui Wang, Li Zhao, Jing Zhang, Haoyu Wang, Xinping Xu, Ji Dong, Juan Wang, Binwei Yao, Jiabin Gu. Metformin Ameliorates 2.856 GHz Microwave- Radiation-Induced Reproductive Impairments in Male Rats via Inhibition of Oxidative Stress and Apoptosis. International journal of molecular sciences. vol 24. issue 15. 2023-08-12. PMID:37569626. |
in particular, metformin can ameliorate microwave-radiation-induced oxidative injury and mitigate apoptosis in the testis, as determined by glutathione/-oxidized glutathione (gsh/gssg), lipid peroxidation, and protein expression of heme oxygenase-1 (ho-1). |
2023-08-12 |
2023-08-16 |
rat |
| Rong Xu, Pengxiang Xu, Haiyan Wei, Yong Huang, Xiaodan Zhu, Chuanming Lin, Zhimin Yan, Liuyan Xin, Lin Li, Weiming Lv, Shuqin Zeng, Guiyou Tian, Jinze Ma, Bo Cheng, Huiqiang Lu, Yijian Che. Ticlopidine induces embryonic development toxicity and hepatotoxicity in zebrafish by upregulating the oxidative stress signaling pathway. Ecotoxicology and environmental safety. vol 262. 2023-08-02. PMID:37531924. |
oxidative stress, metabolic disorders, hepatocyte apoptosis, lipid peroxidation, and inflammatory responses can all lead to hepatic liver damage, which can cause hepatotoxicity. |
2023-08-02 |
2023-08-14 |
zebrafish |
| Xihao Cheng, Chao Yu, Xinquan Yang, Fudi Wang, Junxia Mi. A Panoramic View of Ferroptosis in Cardiovascular Disease. Kidney diseases (Basel, Switzerland). vol 9. issue 3. 2023-07-27. PMID:37497204. |
ferroptosis, an iron-dependent form of programmed cell death, is characterized by the lethal accumulation of lipid peroxidation, which is morphologically, biochemically, and genetically distinct from apoptosis, necrosis, and pyroptosis. |
2023-07-27 |
2023-08-14 |
Not clear |
| Seunghee Lee, Narae Hwang, Byeong Geun Seok, Sangguk Lee, Seon-Jin Lee, Su Wol Chun. Autophagy mediates an amplification loop during ferroptosis. Cell death & disease. vol 14. issue 7. 2023-07-25. PMID:37491375. |
ferroptosis is defined as a reactive oxygen species (ros)-dependent cell death related to iron accumulation and lipid peroxidation, which is different from apoptosis, necrosis, autophagy, and other forms of cell death. |
2023-07-25 |
2023-08-14 |
Not clear |
| Ye Yuan, Chunyu Tian, Qi Wang, Xinyu Qiu, Yufang Wang, Hulin Jiang, Jifu Hao, Yujing H. Synergistic Amplification of Ferroptosis with Liposomal Oxidation Catalyst and Gpx4 Inhibitor for Enhanced Cancer Therapy. Advanced healthcare materials. 2023-07-17. PMID:37458333. |
as a distinctly different way from apoptosis, ferroptosis can cause cell death through excessive accumulation of lipid peroxide (lpo) and show great potential for cancer therapy. |
2023-07-17 |
2023-08-14 |
Not clear |
| Lucas P Gartzke, Koen D W Hendriks, Femke Hoogstra-Berends, Christian P Joschko, Anne-Lise Strandmoe, Pieter C Vogelaar, Guido Krenning, Robert H Hennin. Inhibition of Ferroptosis Enables Safe Rewarming of HEK293 Cells following Cooling in University of Wisconsin Cold Storage Solution. International journal of molecular sciences. vol 24. issue 13. 2023-07-14. PMID:37446116. |
thus, we explored cooling effects on lipid peroxidation and adenosine triphosphate (atp) levels and the actions of blockers of apoptosis and ferroptosis, and of compounds enhancing mitochondrial function. |
2023-07-14 |
2023-08-14 |
human |
| Ajay Guru, Ahmed Rady, Noura M Darwish, Guilherme Malafaia, Selvaraj Arokiyara, Jesu Arockiar. Synergetic Effects of Polyethylene Microplastic and Abamectin Pesticides on the Eyes of Zebrafish Larvae and Adults Through Activation of Apoptosis Signaling Pathways. Environmental toxicology and pharmacology. 2023-07-09. PMID:37423395. |
a significant increase in reactive oxygen species (ros), lipid peroxidation, apoptosis, and impairment in antioxidant response was observed in zebrafish larvae. |
2023-07-09 |
2023-08-14 |
zebrafish |
| Moneerah J Alqahtani, Walaa A Negm, Hebatallah M Saad, Esraa A Salem, Ismail A Hussein, Hanaa A Ibrahi. Fenofibrate and Diosmetin in a rat model of testicular toxicity: New insight on their protective mechanism through PPAR-α/NRF-2/HO-1 signaling pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 165. 2023-07-06. PMID:37413905. |
interestingly, fen and d diminished the harmful effects of cis on testes via upregulation of the antioxidant activities and downregulation of lipid peroxidation, apoptosis, and inflammation. |
2023-07-06 |
2023-08-14 |
rat |
| Esra Aktas Senocak, Necati Utlu, Seyda Kurt, Sefa Kucukler, Fatih Mehmet Kandemi. Sodium Pentaborate Prevents Acetaminophen-Induced Hepatorenal Injury by Suppressing Oxidative Stress, Lipid Peroxidation, Apoptosis, and Inflammatory Cytokines in Rats. Biological trace element research. 2023-07-01. PMID:37393388. |
sodium pentaborate prevents acetaminophen-induced hepatorenal injury by suppressing oxidative stress, lipid peroxidation, apoptosis, and inflammatory cytokines in rats. |
2023-07-01 |
2023-08-14 |
rat |
| Chuchu Gong, Zhengyan Gu, Xinkang Zhang, Qingqiang Xu, Guanchao Mao, Zhipeng Pei, Wenqi Meng, Jinfeng Cen, Jihao Liu, Xiaowen He, Mingxue Sun, Kai Xia. HMSCs exosome-derived miR-199a-5p attenuates sulfur mustard-associated oxidative stress via the CAV1/NRF2 signalling pathway. Journal of cellular and molecular medicine. 2023-06-30. PMID:37386746. |
we noted that hmscs-ex-derived mir-199a-5p played a vital role in reducing pneumonocyte oxidative stress and apoptosis by reducing reactive oxygen species, lipid peroxidation products and increasing the activities of antioxidant enzymes in beas-2b cells and mouse models after exposure to sm for 24 h. |
2023-06-30 |
2023-08-14 |
mouse |
| Wei-Wei Chen, Fu-Qiang Sun, Bo Wang, Xiao-Xiao Tian, Rong-Ping Zhang, Wen-Bo Li. T817MA regulates mitochondrial dynamics via Sirt1 and Arc following subarachnoid hemorrhage. Neuroscience. 2023-06-29. PMID:37385332. |
t817ma treatment significantly inhibited lipid peroxidation, reduced neuronal apoptosis and attenuated mitochondrial fragmentation. |
2023-06-29 |
2023-08-14 |
rat |
| Ren Xu, Wanning Wang, Wenlong Zhan. Ferroptosis and the bidirectional regulatory factor p53. Cell death discovery. vol 9. issue 1. 2023-06-29. PMID:37386007. |
ferroptosis is a type of regulated cell death characterized by iron-mediated lipid peroxidation, in contrast with apoptosis, autophagy, and necrosis. |
2023-06-29 |
2023-08-14 |
Not clear |
| Sheikh Azimullah, Mohamed Fizur Nagoor Meeran, Khatija Ayoob, Seenipandi Arunachalam, Shreesh Ojha, Rami Beira. Tannic Acid Mitigates Rotenone-Induced Dopaminergic Neurodegeneration by Inhibiting Inflammation, Oxidative Stress, Apoptosis, and Glutamate Toxicity in Rats. International journal of molecular sciences. vol 24. issue 12. 2023-06-28. PMID:37373023. |
however, ta treatment was observed to reduce lipid peroxidation, prevent loss of endogenous antioxidants, and inhibit the release and synthesis of proinflammatory cytokines, in addition to the favorable modulation of apoptosis and autophagic pathways. |
2023-06-28 |
2023-08-14 |
human |
| P Alipour-Jenaghard, H Daghigh-Kia, R Masoud. Preservation of the quality and fertility potential of post-thawed rooster sperm using MitoQ. Theriogenology. vol 208. 2023-06-19. PMID:37336065. |
after thawing, sperm motility, membrane functionality, abnormal morphology, mitochondria active potential, acrosome integrity, viability, apoptosis status, lipid peroxidation, dna fragmentation, ros concentration and fertility potential were evaluated. |
2023-06-19 |
2023-08-14 |
chicken |
| P Alipour-Jenaghard, H Daghigh-Kia, R Masoud. Preservation of the quality and fertility potential of post-thawed rooster sperm using MitoQ. Theriogenology. vol 208. 2023-06-19. PMID:37336065. |
on the other hand, lipid peroxidation, apoptosis rate, dna fragmentation and ros concentration were lower (p ≤ 0.05) in groups received 10 and 100 nm mitoq compared to other groups. |
2023-06-19 |
2023-08-14 |
chicken |
| Yingying Chen, Huan Tao, Fujue Wang, Pengqiang Wu, Jie Gao, Xue Zhang, Zhengcang He, Zhencang Zhou, Yongqian Ji. Artesunate synergistically promotes sorafenib‑induced apoptosis and ferroptosis in non‑Hodgkin lymphoma cells through inhibition of the STAT3 pathway. Oncology reports. vol 50. issue 1. 2023-06-16. PMID:37326033. |
cell viability assay, flow cytometry, malondialdehyde assay, gsh assay and western blotting were performed to evaluate cell viability, and changes in apoptosis, autophagic vacuoles, reactive oxygen species, mitochondrial membrane potential, lipid peroxidation and protein expression. |
2023-06-16 |
2023-08-14 |
Not clear |
| Hoda Javaheri Barfourooshi, Nader Asadzadeh, Reza Masoud. The mitochondria-targeted antioxidant "MitoQ" preserves quality and reproductive performance of ram spermatozoa cryopreserved in soybean lecithin-based extender. Theriogenology. vol 208. 2023-06-10. PMID:37301168. |
motility and velocity characteristics, lipid peroxidation, acrosome integrity, membrane functionality, mitochondria active potential, viability, apoptosis status, dna fragmentation, ros concentration and reproductive performance were evaluated after thawing. |
2023-06-10 |
2023-08-14 |
Not clear |
| Hoda Javaheri Barfourooshi, Nader Asadzadeh, Reza Masoud. The mitochondria-targeted antioxidant "MitoQ" preserves quality and reproductive performance of ram spermatozoa cryopreserved in soybean lecithin-based extender. Theriogenology. vol 208. 2023-06-10. PMID:37301168. |
in results, 10 and 100 nm mitoq presented higher (p ≤ 0.05) total motility, progressive motility, average path velocity, acrosome integrity, membrane functionality, mitochondria active potential and viability as well as lower (p ≤ 0.05) lipid peroxidation, apoptosis status, dna fragmentation and ros concentration compared to the control group and the other treatments. |
2023-06-10 |
2023-08-14 |
Not clear |
| Nadia Z Shaban, Fatma H El-Rashidy, Amany H Adam, Doha M Beltagy, Alaa E Ali, Ahmed A Abde-Alaziz, Iman M Talaa. Anticancer role of mango (Mangifera indica L.) peel and seed kernel extracts against 7,12- dimethylbenz[a]anthracene-induced mammary carcinogenesis in female rats. Scientific reports. vol 13. issue 1. 2023-05-11. PMID:37169856. |
the study focused on the assessment of markers of endocrine derangement [serum 17-β estradiol (e2)], apoptosis [caspase-3 and deoxyribonucleic acid fragmentation (dnaf)], and oxidative stress [lipid peroxidation and antioxidants (glutathione, glutathione-s-transferase, glutathione reductase, glutathione peroxidase, and superoxide dismutase)]. |
2023-05-11 |
2023-08-14 |
rat |
| Ying Yang, Ying Xu, Congzhao Zhao, Lirong Zhang, Aslibek Nuerbol, Lili Wang, Yang Jia. Pronounced Enhancement in Radiosensitization of Esophagus Cancer Cultivated in Docosahexaenoic Acid via the Frontiers in medicine. vol 9. 2023-05-09. PMID:37153924. |
we used cell cycle assay, lipid peroxidation assay, comet assay, and apoptosis assay to unearth the potential causes. |
2023-05-09 |
2023-08-14 |
mouse |