| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Amira Abo Bakr, Mohamed Ali, Khairy Ibrahi. Garlic and allopurinol alleviate the apoptotic pathway in rats' brain following exposure to fipronil insecticide. Environmental analysis, health and toxicology. vol 37. issue 4. 2023-03-14. PMID:36916050. |
interestingly, co-administration with garlic or allopurinol improved the lipid peroxidation, antioxidant disturbance, and apoptosis induced by fipronil in the brain tissues. |
2023-03-14 |
2023-08-14 |
rat |
| Yang Xie, Feng Shen, Yafang He, Canjie Guo, Ruixu Yang, Haixia Cao, Qin Pan, Jiangao Fa. Gamma-Muricholic Acid Inhibits Nonalcoholic Steatohepatitis: Abolishment of Steatosis-Dependent Peroxidative Impairment by FXR/SHP/LXRα/FASN Signaling. Nutrients. vol 15. issue 5. 2023-03-11. PMID:36904254. |
here, the effect and mechanism of γ-muricholic acid (γ-mca) on nash were investigated on the basis of its actions in hepatic steatosis, lipid peroxidation, peroxidative injury, hepatocyte apoptosis, and its nafld activity score (nas). |
2023-03-11 |
2023-08-14 |
mouse |
| Sangeetha Nithiyanandam, Sabina Evan Princ. Caesalpinia bonducella Counteracts Paracetamol-Instigated Hepatic Toxicity via Modulating TNF-α and IL-6/10 Expression and Bcl-2 and Caspase-8/3 Signalling. Applied biochemistry and biotechnology. 2023-02-28. PMID:36853441. |
in conclusion, asecb pre-treatment exerts potent liver protection against paracetamol-instigated hepatotoxicity evidenced by mitigation of oxidative stress, lipid peroxidation, inflammation, and apoptosis. |
2023-02-28 |
2023-08-14 |
rat |
| Azza Dammak, Cristina Pastrana, Alba Martin-Gil, Carlos Carpena-Torres, Assumpta Peral Cerda, Mirjam Simovart, Pilar Alarma, Fernando Huete-Toral, Gonzalo Carraced. Oxidative Stress in the Anterior Ocular Diseases: Diagnostic and Treatment. Biomedicines. vol 11. issue 2. 2023-02-25. PMID:36830827. |
furthermore, oxidative stress is related to mitochondrial dysfunction, dna damage, lipid peroxidation, protein modification, apoptosis, and inflammation, which are involved in anterior ocular disease progression such as dry eye, keratoconus, uveitis, and cataract. |
2023-02-25 |
2023-08-14 |
Not clear |
| Hexi Yang, Fumin Tai, Tiantian Wang, Xiaofei Zheng, Changhui Ge, Yide Qin, Hanjiang F. Hydrogen peroxide and iron ions can modulate lipid peroxidation, apoptosis, and the cell cycle, but do not have a significant effect on DNA double-strand break. Biochemical and biophysical research communications. vol 651. 2023-02-23. PMID:36822125. |
hydrogen peroxide and iron ions can modulate lipid peroxidation, apoptosis, and the cell cycle, but do not have a significant effect on dna double-strand break. |
2023-02-23 |
2023-08-14 |
Not clear |
| Chuanjiao Sun, Lijun Gao, Libin Xu, Qiaomei Zheng, Shuzhen Sun, Xiaoxue Liu, Zigang Zhang, Zhongwei Tian, Tingbo Dai, Jianyun Su. Melatonin alleviates chromium toxicity by altering chromium subcellular distribution and enhancing antioxidant metabolism in wheat seedlings. Environmental science and pollution research international. 2023-02-16. PMID:36797388. |
furthermore, mt pre-treatment alleviated cr-induced oxidative damage by diminishing lipid peroxidation and cell apoptosis, profiting from the enhanced scavenging ability of ros as a result of the mt-induced increase in the activities of superoxide dismutase, catalase, ascorbate peroxidase, and glutathione reductase, and the related encoding gene expression levels of tasod2, tacat, taapx, and tagr. |
2023-02-16 |
2023-08-14 |
Not clear |
| Azar Hosseini, Mohaddeseh Sadat Alavi, Amir Reza Shahraki, Arezoo Rajabian, Amir Reza Afshari, Prashant Kesharwani, Amirhossein Sahebka. Psidium guajava induces cytotoxicity in human malignant glioblastoma cell line: Role of reactive oxygen species (ROS). Toxicology in vitro : an international journal published in association with BIBRA. 2023-02-09. PMID:36758825. |
lipid peroxidation assay, reactive oxygen species (ros) production, and apoptosis rate were evaluated 24 h after treatment by extracts of p. guajava. |
2023-02-09 |
2023-08-14 |
human |
| Azar Hosseini, Mohaddeseh Sadat Alavi, Amir Reza Shahraki, Arezoo Rajabian, Amir Reza Afshari, Prashant Kesharwani, Amirhossein Sahebka. Psidium guajava induces cytotoxicity in human malignant glioblastoma cell line: Role of reactive oxygen species (ROS). Toxicology in vitro : an international journal published in association with BIBRA. 2023-02-09. PMID:36758825. |
also, treatment by extracts increased lipid peroxidation, ros production, and apoptosis in a dose-dependent manner. |
2023-02-09 |
2023-08-14 |
human |
| Yi Lyu, Jin Yang, LiXia Cheng, ZhaoFei Li, JinPing Zhen. Benzo(a)pyrene-induced mitochondrial respiration and glycolysis disturbance in human neuroblastoma cells. The Journal of toxicological sciences. vol 48. issue 2. 2023-02-01. PMID:36725024. |
bha supplementation recovered the mitochondrial respiration, synchronously attenuated intracellular ros generation and lipid peroxidation, and simultaneously reversed the abnormal changes in antioxidant biomarkers, then rescued bap-induced cell apoptosis. |
2023-02-01 |
2023-08-14 |
human |
| Syahru Agung Setiawan, Winston Zhenhao Liu, Pei-Wei Weng, Chia Hwa Lee, Vijesh Kumar Yadav, Mardiah Suci Hardianti, Chi-Tai Yeh, Tsu-Yi Cha. Synergistic disruption of BTK and BCL-2 causes apoptosis while inducing ferroptosis in double-hit lymphoma. European journal of pharmacology. 2023-01-24. PMID:36693553. |
the drug combination triggered apoptosis and ferroptosis, with the latter being characterized by reactive oxygen species (ros) accumulation, extensive lipid peroxidation, and depletion of reduced glutathione. |
2023-01-24 |
2023-08-14 |
Not clear |
| Mirjana T Macvanin, Zoran Gluvic, Sonja Zafirovic, Xin Gao, Magbubah Essack, Esma R Isenovi. The protective role of nutritional antioxidants against oxidative stress in thyroid disorders. Frontiers in endocrinology. vol 13. 2023-01-23. PMID:36686463. |
although oxs is a consequence of normal body and organ physiology, severely impaired oxidative homeostasis results in dna hydroxylation, protein denaturation, lipid peroxidation, and apoptosis, ultimately compromising cells' function and viability. |
2023-01-23 |
2023-08-14 |
Not clear |
| Jiajiao Liu, Guanyin Jiang, Pengfei He, Xing Du, Zhenming Hu, Fuxiang L. Mechanism of ferroptosis in traditional chinese medicine for clinical treatment: A review. Frontiers in pharmacology. vol 13. 2023-01-23. PMID:36686700. |
ferroptosis is an iron-dependent regulation of cell death driven by lipid peroxidation, which is intracellularly dependent on iron and independent of other metals, and morphologically, biochemically, and genetically distinct from apoptosis, necrosis, and autophagy. |
2023-01-23 |
2023-08-14 |
Not clear |
| Mingliang Chen, Zhihao Shi, Yuqiu Sun, Haoran Ning, Xinyu Gu, Lei Zhan. Prospects for Anti-Tumor Mechanism and Potential Clinical Application Based on Glutathione Peroxidase 4 Mediated Ferroptosis. International journal of molecular sciences. vol 24. issue 2. 2023-01-21. PMID:36675129. |
ferroptosis, characterized by excessive iron accumulation and lipid peroxidation, is a novel form of iron-dependent cell death, which is morphologically, genetically, and biochemically distinct from other known cell death types, such as apoptosis, necrosis, and autophagy. |
2023-01-21 |
2023-08-14 |
Not clear |
| Ting-Ting Yi, Li-Mei Zhang, Xiang-Nan Huan. Glycyrrhizic acid protects against temporal lobe epilepsy in young rats by regulating neuronal ferroptosis through the miR-194-5p/PTGS2 axis. The Kaohsiung journal of medical sciences. 2023-01-17. PMID:36647717. |
briefly, different doses of ga (20, 40, and 60 mg/kg) reduced the epileptic score, frequency, and duration in tle young rats, along with reductions in iron content, lipid peroxidation, neuronal injury, and apoptosis in the hippocampus. |
2023-01-17 |
2023-08-14 |
rat |
| Xu Zhao, Kan Fu, Kai-Ping Xiang, Lan-Ying Wang, Yun-Fei Zhang, Yan-Ping Lu. Comparison of the chronic and multigenerational toxicity of racemic glufosinate and l-glufosinate to Caenorhabditis elegans at environmental concentrations. Chemosphere. 2023-01-17. PMID:36649895. |
these phenomena caused oxidative damage (protein and membrane lipid peroxidation) and further induced apoptosis. |
2023-01-17 |
2023-08-14 |
caenorhabditis_elegans |
| Ruizhi Hu, Chen Dai, Xinyue Dai, Caihong Dong, Hui Huang, Xinran Song, Wei Feng, Li Ding, Yu Chen, Bo Zhan. Topology regulation of nanomedicine for autophagy-augmented ferroptosis and cancer immunotherapy. Science bulletin. 2023-01-09. PMID:36621435. |
iron accumulation and lipid peroxidation form the basis of ferroptosis, potentially circumventing the limitations of apoptosis in cancer treatment. |
2023-01-09 |
2023-08-14 |
Not clear |
| Cristóbal Ávila, José Ignacio Vinay, Marzia Arese, Luciano Saso, Ramón Rodrig. Antioxidant Intervention against Male Infertility: Time to Design Novel Strategies. Biomedicines. vol 10. issue 12. 2022-12-23. PMID:36551814. |
among the mechanisms likely plausible to account for idiopathic cases, oxidative stress (os) has currently been increasingly recognized as a key factor in mi, through phenomena such as mitochondrial dysfunction, lipid peroxidation, dna damage and fragmentation and finally, sperm apoptosis. |
2022-12-23 |
2023-08-14 |
Not clear |
| Sagarika Majhi, Lubhan Singh, Mohd Yasi. Evaluation of Ameliorative Effect of Quercetin and Candesartan in Doxorubicin-Induced Cardiotoxicity. Vascular health and risk management. vol 18. 2022-12-20. PMID:36536768. |
these are free-radical generation, myocyte apoptosis, lipid peroxidation, mitochondrial deterioration, and direct repression of muscle-specific gene expression. |
2022-12-20 |
2023-08-14 |
Not clear |
| Peng-Wei Ma, Wei-Long Wang, Jia-Wei Chen, Hao Yuan, Pei-Heng Lu, Wei Gao, Xue-Rui Ding, Yu-Qiang Lun, Rui Liang, Zu-Hong He, Qian Yang, Lian-Jun L. Treatment with the Ferroptosis Inhibitor Ferrostatin-1 Attenuates Noise-Induced Hearing Loss by Suppressing Ferroptosis and Apoptosis. Oxidative medicine and cellular longevity. vol 2022. 2022-12-19. PMID:36531206. |
we observed ros overload and lipid peroxidation, which led to outer hair cell (ohc) apoptosis and ferroptosis, in the mouse cochlea after noise exposure. |
2022-12-19 |
2023-08-14 |
mouse |
| Tianhao Cong, Yingen Luo, Yan Fu, Yu Liu, Yujie Li, Xiao L. New perspectives on ferroptosis and its role in hepatocellular carcinoma. Chinese medical journal. vol 135. issue 18. 2022-12-16. PMID:36525603. |
ferroptosis is a kind of regulated cell death (rcd); unlike apoptosis, ferroptosis is an iron-dependent type of rcd driven by lipid peroxidation. |
2022-12-16 |
2023-08-14 |
Not clear |