| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ajay Guru, Jesu Arockiara. Exposure to environmental pollutant bisphenol A causes oxidative damage and lipid accumulation in Zebrafish larvae: Protective role of WL15 peptide derived from cysteine and glycine-rich protein 2. Journal of biochemical and molecular toxicology. 2022-09-15. PMID:36106391. |
bpa exposure disrupted the antioxidant enzymes, apoptosis, and nitric oxide and led to changes in biochemical markers including alkaline phosphatase, lactate dehydrogenase, lipid peroxidation, glutathione s-transferases, glutathione peroxidase, and reduced glutathione. |
2022-09-15 |
2023-08-14 |
zebrafish |
| Hager H Shaaban, Ibrahim Alzaim, Ahmed El-Mallah, Rania G Aly, Ahmed F El-Yazbi, Ahmed Wahi. Metformin, pioglitazone, dapagliflozin and their combinations ameliorate manifestations associated with NAFLD in rats via anti-inflammatory, anti-fibrotic, anti-oxidant and anti-apoptotic mechanisms. Life sciences. 2022-09-14. PMID:36103959. |
rats were fed an atherogenic diet containing 1.25 % cholesterol, 0.5 % cholic acid and 60 % cocoa butter for 6 weeks causing a number of metabolic and hepatic alterations including insulin resistance, dyslipidemia, systemic inflammation, increased hepatic oxidative stress and lipid peroxidation, hepatic steatosis, lobular inflammation, as well as increased markers of liver inflammation and hepatocyte apoptosis. |
2022-09-14 |
2023-08-14 |
rat |
| Gokul Sudhakaran, Ravi Rajesh, Ajay Guru, B Haridevamuthu, Raghul Murugan, Nattamai Bhuvanesh, Mohammad Ahmad Wadaan, Shalid Mahboob, Annie Juliet, Pushparathinam Gopinath, Jesu Arockiara. Deacetylated nimbin analog N2 fortifies alloxan-induced pancreatic β-cell damage in insulin-resistant zebrafish larvae by upregulating phosphoenolpyruvate carboxykinase (PEPCK) and insulin levels. Toxicology and applied pharmacology. 2022-09-11. PMID:36089001. |
a 500 μm of alloxan was exposed to zebrafish larvae for 24 h to induce oxidative stress in the pancreatic β-cells and co-exposed with n2 to study the protection of n2 by inhibiting ros by dcfh-da, dhe and nda staining along with cellular damage, apoptosis and lipid peroxidation. |
2022-09-11 |
2023-08-14 |
zebrafish |
| Rajalakshmi Ramachandran, Ramya Parthasarathy, Sangeetha Dhayala. Silver nanoparticles synthesized by Euphorbia hirta exhibited antibacterial activity and induced apoptosis through downregulation of PI3Kγ mediated PI3K/Akt/mTOR/p70S6K in human lung adenocarcinoma A549 cells. Environmental toxicology. 2022-09-08. PMID:36073799. |
results showed that eh-agnps exhibited effective antibacterial activity against bacterial pathogens, established dose-dependent cytotoxicity on a549 cells, and persuaded apoptosis, as evidenced by increased lipid peroxidation and decreased levels of antioxidants. |
2022-09-08 |
2023-08-14 |
human |
| Sobana Sundram, Suganya Baskar, Alagumanian Subramania. Green synthesized nickel doped cobalt ferrite nanoparticles exhibit antibacterial activity and induce reactive oxygen species mediated apoptosis in MCF-7 breast cancer cells through inhibition of PI3K/Akt/mTOR pathway. Environmental toxicology. 2022-09-08. PMID:36073959. |
the results showed that the administration of 0.8% ni-cfo nanoparticles promoted apoptosis, and reduced cell adhesion and migration of mcf-7 cells, as demonstrated by increased lipid peroxidation, decreased antioxidant levels such as superoxide dismutase, catalase, and glutathione peroxidase, and increased formation of reactive oxygen species. |
2022-09-08 |
2023-08-14 |
Not clear |
| Irma Virant-Klun, Senka Imamovic-Kumalic, Bojana Pinte. From Oxidative Stress to Male Infertility: Review of the Associations of Endocrine-Disrupting Chemicals (Bisphenols, Phthalates, and Parabens) with Human Semen Quality. Antioxidants (Basel, Switzerland). vol 11. issue 8. 2022-08-26. PMID:36009337. |
moreover, edcs can elevate ros production and lipid peroxidation, increase apoptosis, induce epigenetic modifications, and change the y:x sperm chromosome ratio and sperm protein composition. |
2022-08-26 |
2023-08-14 |
human |
| Raghul Murugan, Ravi Rajesh, Ajay Guru, B Haridevamuthu, Bader O Almutairi, Mikhlid H Almutairi, Annie Juliet, S Renganayagi, Pushparathinam Gopinath, Jesu Arockiara. Deacetylepoxyazadiradione Derived from Epoxyazadiradione of Neem (Azadirachta indica A. Juss) Fruits Mitigates LPS-Induced Oxidative Stress and Inflammation in Zebrafish Larvae. Chemistry & biodiversity. 2022-08-26. PMID:36026548. |
the percentage of ros, lipid peroxidation, nitric oxide and apoptosis were reduced significantly in nf2 treated lps-stressed zebrafish larvae. |
2022-08-26 |
2023-08-14 |
rat |
| Zimin Wang, Sikai Wu, Chengchu Zhu, Jianfei She. The role of ferroptosis in esophageal cancer. Cancer cell international. vol 22. issue 1. 2022-08-23. PMID:35999642. |
ferroptosis, a novel regulatory cell death model, that is different from traditional apoptosis and characterized by increased fenton reaction mediated by intracellular free iron and lipid peroxidation of cell membrane. |
2022-08-23 |
2023-08-14 |
Not clear |
| Taha Ghantabpour, Maryam Shabani Nashtaei, Saeid Nekoonam, Hossein Rezaei, Fardin Amid. The Effect of Astaxanthin on Motility, Viability, Reactive Oxygen Species, Apoptosis, and Lipid Peroxidation of Human Spermatozoa During the Freezing-Thawing Process. Biopreservation and biobanking. vol 20. issue 4. 2022-08-19. PMID:35984938. |
the effect of astaxanthin on motility, viability, reactive oxygen species, apoptosis, and lipid peroxidation of human spermatozoa during the freezing-thawing process. |
2022-08-19 |
2023-08-14 |
human |
| Yasemin Bicer, Hulya Elbe, Melike Karayakali, Gurkan Yigitturk, Umit Yilmaz, Osman Cengil, Mohammed Raed Abdullah Al Gburi, Eyup Altino. Neuroprotection by melatonin against acrylamide-induced brain damage in pinealectomized rats. Journal of chemical neuroanatomy. 2022-08-11. PMID:35952951. |
moreover, melatonin suppressed lipid peroxidation, inflammatory pathways and apoptosis in acr-intoxicated brain tissues. |
2022-08-11 |
2023-08-14 |
rat |
| Yulong Wang, Li Ou, Xirong Li, Tingyu Zheng, Wei-Pei Zhu, Ping Li, Lijun Wu, Tianlan Zha. The mitochondrial RNA polymerase POLRMT promotes skin squamous cell carcinoma cell growth. Cell death discovery. vol 8. issue 1. 2022-08-03. PMID:35922422. |
in the polrmt shrna virus-treated a431 xenograft tissues, polrmt depletion, mtdna transcription inhibition, cell apoptosis, lipid peroxidation and atp depletion were detected. |
2022-08-03 |
2023-08-14 |
mouse |
| Negin Amini, Maryam Maleki, Mohammad Badav. Nephroprotective activity of naringin against chemical-induced toxicity and renal ischemia/reperfusion injury: A review. Avicenna journal of phytomedicine. vol 12. issue 4. 2022-07-05. PMID:35782769. |
renal injury is accompanied by oxidative stress which results in cellular apoptosis, lipid peroxidation, and reduction of antioxidant levels. |
2022-07-05 |
2023-08-14 |
Not clear |
| Ruiqi Fan, Yujun Sun, Mengxue Wang, Qian Wang, Aifang Jiang, Tingting Yan. New Insights on Ferroptosis and Gynecological Malignancies. Frontiers in molecular biosciences. vol 9. 2022-07-01. PMID:35775079. |
ferroptosis is a new type of cell death different from apoptosis and necrosis, which can regulate the accumulation of lipid peroxidation through different pathways, ultimately leading to cell death. |
2022-07-01 |
2023-08-14 |
Not clear |
| Benedikt Kolbrink, Friedrich Alexander von Samson-Himmelstjerna, Maja Lucia Messtorff, Theresa Riebeling, Raphael Nische, Jessica Schmitz, Jan Hinrich Bräsen, Ulrich Kunzendorf, Stefan Krautwal. Vitamin K1 inhibits ferroptosis and counteracts a detrimental effect of phenprocoumon in experimental acute kidney injury. Cellular and molecular life sciences : CMLS. vol 79. issue 7. 2022-06-28. PMID:35763128. |
ferroptosis, a type of iron-dependent programmed cell death distinct from apoptosis, necroptosis, and other types of cell death, is characterized by lipid peroxidation, reactive oxygen species production, and mitochondrial dysfunction. |
2022-06-28 |
2023-08-14 |
Not clear |
| Jun Bai, Yusong Zhou, Xin Luo, Jia Hai, Xuemeng Si, Jun Li, Huiyang Fu, Zhaolai Dai, Ying Yang, Zhenlong W. Roles of stress response-related signaling and its contribution to the toxicity of zearalenone in mammals. Comprehensive reviews in food science and food safety. 2022-06-25. PMID:35751400. |
biochemically, the deleterious effects of zea are associated with apoptosis, dna damage, and lipid peroxidation by regulating the expression of genes implicated in these biological processes. |
2022-06-25 |
2023-08-14 |
Not clear |
| Shaokun Wang, Wei Wei, Ning Ma, Yongliang Qu, Qiuju Li. Molecular mechanisms of ferroptosis and its role in prostate cancer therapy. Critical reviews in oncology/hematology. 2022-06-13. PMID:35697233. |
ferroptosis is a novel form of programmed cell death characterized by iron overload and the accumulation of lipid peroxidation, which differs from the regulated cell death modes of necrosis, apoptosis, and autophagy. |
2022-06-13 |
2023-08-14 |
Not clear |
| Xue Li, Dongyue Zhou, Di Yang, Yunhua Fu, Xingyu Tao, Xuan Hu, Yulin Dai, Hao Yu. Isoquercitrin Attenuates Osteogenic Injury in MC3T3 Osteoblastic Cells and the Zebrafish Model via the Keap1-Nrf2-ARE Pathway. Molecules (Basel, Switzerland). vol 27. issue 11. 2022-06-10. PMID:35684398. |
furthermore, iq significantly decreased ros production, apoptosis, and lipid peroxidation in aaph-treated 72 h post-fertilization (hpf) zebrafish, as observed via dcfh-da, acridine orange (ao), and a 1,3-bis(diphenylphosphino) propane (dppp) probe, respectively. |
2022-06-10 |
2023-08-14 |
zebrafish |
| Yuting Guo, Wei Zhang, Xinger Zhou, Shihao Zhao, Jian Wang, Yi Guo, Yichao Liao, Haihui Lu, Jie Liu, Yanbin Cai, Jiao Wu, Mingzhi She. Roles of Ferroptosis in Cardiovascular Diseases. Frontiers in cardiovascular medicine. vol 9. 2022-06-09. PMID:35677693. |
ferroptosis is an iron-dependent regulated cell death characterized by lipid peroxidation and iron overload, which is different from other types of programmed cell death, including apoptosis, necroptosis, autophagy, and pyroptosis. |
2022-06-09 |
2023-08-14 |
Not clear |
| Ali Ahmadi, Zoha Mortazavi, Soghra Mehri, Hossein Hosseinzade. Scutellaria baicalensis and its constituents baicalin and baicalein as antidotes or protective agents against chemical toxicities: a comprehensive review. Naunyn-Schmiedeberg's archives of pharmacology. 2022-06-08. PMID:35676380. |
in conclusion, the protective effects of sb and its flavonoids can be mainly attributed to increase in antioxidants enzymes, inhibition of lipid peroxidation, reduction of inflammatory cytokines, and suppression of apoptosis pathway. |
2022-06-08 |
2023-08-14 |
Not clear |
| Qiyu Qin, Naiji Yu, Yuxiang Gu, Weishaer Ke, Qi Zhang, Xin Liu, Kaijun Wang, Min Che. Inhibiting multiple forms of cell death optimizes ganglion cells survival after retinal ischemia reperfusion injury. Cell death & disease. vol 13. issue 5. 2022-05-31. PMID:35637215. |
in this study, we first demonstrated that apart from necroptosis, which occurs before apoptosis, ferroptosis, which is characterized by iron deposition and lipid peroxidation, is involved in the whole course of retinal ir in mice. |
2022-05-31 |
2023-08-13 |
mouse |