| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zimin Wang, Sikai Wu, Chengchu Zhu, Jianfei She. The role of ferroptosis in esophageal cancer. Cancer cell international. vol 22. issue 1. 2022-08-23. PMID:35999642. |
ferroptosis, a novel regulatory cell death model, that is different from traditional apoptosis and characterized by increased fenton reaction mediated by intracellular free iron and lipid peroxidation of cell membrane. |
2022-08-23 |
2023-08-14 |
Not clear |
| Taha Ghantabpour, Maryam Shabani Nashtaei, Saeid Nekoonam, Hossein Rezaei, Fardin Amid. The Effect of Astaxanthin on Motility, Viability, Reactive Oxygen Species, Apoptosis, and Lipid Peroxidation of Human Spermatozoa During the Freezing-Thawing Process. Biopreservation and biobanking. vol 20. issue 4. 2022-08-19. PMID:35984938. |
the effect of astaxanthin on motility, viability, reactive oxygen species, apoptosis, and lipid peroxidation of human spermatozoa during the freezing-thawing process. |
2022-08-19 |
2023-08-14 |
human |
| Yasemin Bicer, Hulya Elbe, Melike Karayakali, Gurkan Yigitturk, Umit Yilmaz, Osman Cengil, Mohammed Raed Abdullah Al Gburi, Eyup Altino. Neuroprotection by melatonin against acrylamide-induced brain damage in pinealectomized rats. Journal of chemical neuroanatomy. 2022-08-11. PMID:35952951. |
moreover, melatonin suppressed lipid peroxidation, inflammatory pathways and apoptosis in acr-intoxicated brain tissues. |
2022-08-11 |
2023-08-14 |
rat |
| Yulong Wang, Li Ou, Xirong Li, Tingyu Zheng, Wei-Pei Zhu, Ping Li, Lijun Wu, Tianlan Zha. The mitochondrial RNA polymerase POLRMT promotes skin squamous cell carcinoma cell growth. Cell death discovery. vol 8. issue 1. 2022-08-03. PMID:35922422. |
in the polrmt shrna virus-treated a431 xenograft tissues, polrmt depletion, mtdna transcription inhibition, cell apoptosis, lipid peroxidation and atp depletion were detected. |
2022-08-03 |
2023-08-14 |
mouse |
| Negin Amini, Maryam Maleki, Mohammad Badav. Nephroprotective activity of naringin against chemical-induced toxicity and renal ischemia/reperfusion injury: A review. Avicenna journal of phytomedicine. vol 12. issue 4. 2022-07-05. PMID:35782769. |
renal injury is accompanied by oxidative stress which results in cellular apoptosis, lipid peroxidation, and reduction of antioxidant levels. |
2022-07-05 |
2023-08-14 |
Not clear |
| Ruiqi Fan, Yujun Sun, Mengxue Wang, Qian Wang, Aifang Jiang, Tingting Yan. New Insights on Ferroptosis and Gynecological Malignancies. Frontiers in molecular biosciences. vol 9. 2022-07-01. PMID:35775079. |
ferroptosis is a new type of cell death different from apoptosis and necrosis, which can regulate the accumulation of lipid peroxidation through different pathways, ultimately leading to cell death. |
2022-07-01 |
2023-08-14 |
Not clear |
| Benedikt Kolbrink, Friedrich Alexander von Samson-Himmelstjerna, Maja Lucia Messtorff, Theresa Riebeling, Raphael Nische, Jessica Schmitz, Jan Hinrich Bräsen, Ulrich Kunzendorf, Stefan Krautwal. Vitamin K1 inhibits ferroptosis and counteracts a detrimental effect of phenprocoumon in experimental acute kidney injury. Cellular and molecular life sciences : CMLS. vol 79. issue 7. 2022-06-28. PMID:35763128. |
ferroptosis, a type of iron-dependent programmed cell death distinct from apoptosis, necroptosis, and other types of cell death, is characterized by lipid peroxidation, reactive oxygen species production, and mitochondrial dysfunction. |
2022-06-28 |
2023-08-14 |
Not clear |
| Jun Bai, Yusong Zhou, Xin Luo, Jia Hai, Xuemeng Si, Jun Li, Huiyang Fu, Zhaolai Dai, Ying Yang, Zhenlong W. Roles of stress response-related signaling and its contribution to the toxicity of zearalenone in mammals. Comprehensive reviews in food science and food safety. 2022-06-25. PMID:35751400. |
biochemically, the deleterious effects of zea are associated with apoptosis, dna damage, and lipid peroxidation by regulating the expression of genes implicated in these biological processes. |
2022-06-25 |
2023-08-14 |
Not clear |
| Shaokun Wang, Wei Wei, Ning Ma, Yongliang Qu, Qiuju Li. Molecular mechanisms of ferroptosis and its role in prostate cancer therapy. Critical reviews in oncology/hematology. 2022-06-13. PMID:35697233. |
ferroptosis is a novel form of programmed cell death characterized by iron overload and the accumulation of lipid peroxidation, which differs from the regulated cell death modes of necrosis, apoptosis, and autophagy. |
2022-06-13 |
2023-08-14 |
Not clear |
| Xue Li, Dongyue Zhou, Di Yang, Yunhua Fu, Xingyu Tao, Xuan Hu, Yulin Dai, Hao Yu. Isoquercitrin Attenuates Osteogenic Injury in MC3T3 Osteoblastic Cells and the Zebrafish Model via the Keap1-Nrf2-ARE Pathway. Molecules (Basel, Switzerland). vol 27. issue 11. 2022-06-10. PMID:35684398. |
furthermore, iq significantly decreased ros production, apoptosis, and lipid peroxidation in aaph-treated 72 h post-fertilization (hpf) zebrafish, as observed via dcfh-da, acridine orange (ao), and a 1,3-bis(diphenylphosphino) propane (dppp) probe, respectively. |
2022-06-10 |
2023-08-14 |
zebrafish |
| Yuting Guo, Wei Zhang, Xinger Zhou, Shihao Zhao, Jian Wang, Yi Guo, Yichao Liao, Haihui Lu, Jie Liu, Yanbin Cai, Jiao Wu, Mingzhi She. Roles of Ferroptosis in Cardiovascular Diseases. Frontiers in cardiovascular medicine. vol 9. 2022-06-09. PMID:35677693. |
ferroptosis is an iron-dependent regulated cell death characterized by lipid peroxidation and iron overload, which is different from other types of programmed cell death, including apoptosis, necroptosis, autophagy, and pyroptosis. |
2022-06-09 |
2023-08-14 |
Not clear |
| Ali Ahmadi, Zoha Mortazavi, Soghra Mehri, Hossein Hosseinzade. Scutellaria baicalensis and its constituents baicalin and baicalein as antidotes or protective agents against chemical toxicities: a comprehensive review. Naunyn-Schmiedeberg's archives of pharmacology. 2022-06-08. PMID:35676380. |
in conclusion, the protective effects of sb and its flavonoids can be mainly attributed to increase in antioxidants enzymes, inhibition of lipid peroxidation, reduction of inflammatory cytokines, and suppression of apoptosis pathway. |
2022-06-08 |
2023-08-14 |
Not clear |
| Qiyu Qin, Naiji Yu, Yuxiang Gu, Weishaer Ke, Qi Zhang, Xin Liu, Kaijun Wang, Min Che. Inhibiting multiple forms of cell death optimizes ganglion cells survival after retinal ischemia reperfusion injury. Cell death & disease. vol 13. issue 5. 2022-05-31. PMID:35637215. |
in this study, we first demonstrated that apart from necroptosis, which occurs before apoptosis, ferroptosis, which is characterized by iron deposition and lipid peroxidation, is involved in the whole course of retinal ir in mice. |
2022-05-31 |
2023-08-13 |
mouse |
| Gokul Sudhakaran, Pandurangan Prathap, Ajay Guru, B Haridevamuthu, Raghul Murugan, Bader O Almutairi, Mikhlid H Almutairi, Annie Juliet, Pushparathinam Gopinath, Jesu Arockiara. Reverse pharmacology of Nimbin-N2 attenuates alcoholic liver injury and promotes the hepatoprotective dual role of improving lipid metabolism and downregulating the levels of inflammatory cytokines in zebrafish larval model. Molecular and cellular biochemistry. 2022-05-16. PMID:35575874. |
n2 was subjected to admet screening in-silico, and it was observed n2's co-exposure decreased the ros, apoptosis, lipid peroxidation, and macrophage accumulation in the liver of larval zebrafish. |
2022-05-16 |
2023-08-13 |
zebrafish |
| Aziza Alshahrani, Hong Jiang, Pratik Thapa, Na Ding, Yanning Hao, Qiou We. Understanding the Role of the Peroxiredoxin Family in the Regulation of Ferroptosis in Colorectal Cancer. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35556603. |
cell death due to ferroptosis in these cells was demonstrated by the measurement of lipid peroxidation using the sensor bodipy 581/591 c11 and differentiated with other modes of cell death such as apoptosis, autophagy and necrosis by the combined application of various inhibitors. |
2022-05-13 |
2023-08-13 |
Not clear |
| Hichem Moulahoum, Faezeh Ghorbanizamani, Zineb Khiari, Mohamed Toumi, Yasmina Benazzoug, Kerem Tok, Suna Timur, Figen Zihniogl. Artemisia alleviates AGE-induced liver complications via MAPK and RAGE signaling pathways modulation: a combinatorial study. Molecular and cellular biochemistry. 2022-05-11. PMID:35543857. |
additionally, aha reduced inflammatory mediators (il-6, tnfα), oxidative stress markers (no, lpo), and apoptosis (caspase 3). |
2022-05-11 |
2023-08-13 |
Not clear |
| Hana Valenta, Sophie Dupré, Mouna Abdesselem, Tania Bizouarn, Laura Baciou, Oliver Nüsse, Ariane Deniset-Besseau, Marie Erar. Consequences of the constitutive NOX2 activity in living cells: Cytosol acidification, apoptosis, and localized lipid peroxidation. Biochimica et biophysica acta. Molecular cell research. 2022-04-30. PMID:35489654. |
consequences of the constitutive nox2 activity in living cells: cytosol acidification, apoptosis, and localized lipid peroxidation. |
2022-04-30 |
2023-08-13 |
Not clear |
| Lin Chen, Qin Ru, Qi Xiong, Jun Yang, Guodong Xu, Yuxiang W. Potential Effects of Nrf2 in Exercise Intervention of Neurotoxicity Caused by Methamphetamine Oxidative Stress. Oxidative medicine and cellular longevity. vol 2022. 2022-04-28. PMID:35480870. |
methamphetamine can cause oxidative stress-centered lipid peroxidation, endoplasmic reticulum stress, mitochondrial dysfunction, excitatory neurotoxicity, and neuroinflammation and ultimately lead to nerve cell apoptosis, abnormal glial cell activation, and dysfunction of blood-brain barrier. |
2022-04-28 |
2023-08-13 |
Not clear |
| Wenhui Song, Weiyao Zhang, Lizhou Yue, Weiying Li. Revealing the Effects of Endoplasmic Reticulum Stress on Ferroptosis by Two-Channel Real-Time Imaging of pH and Viscosity. Analytical chemistry. 2022-04-18. PMID:35435658. |
besides, different from apoptosis and necrosis, ferroptosis is the result of lipid peroxidation accumulation. |
2022-04-18 |
2023-08-13 |
Not clear |
| An-Guo Wu, Yuan-Yuan Yong, Yi-Ru Pan, Li Zhang, Jian-Ming Wu, Yue Zhang, Yong Tang, Jing Wei, Lu Yu, Betty Yuen-Kwan Law, Chong-Lin Yu, Jian Liu, Cai Lan, Ru-Xiang Xu, Xiao-Gang Zhou, Da-Lian Qi. Targeting Nrf2-Mediated Oxidative Stress Response in Traumatic Brain Injury: Therapeutic Perspectives of Phytochemicals. Oxidative medicine and cellular longevity. vol 2022. 2022-04-14. PMID:35419162. |
most importantly, excessive oxidative stress causes bbb disruption and brings injury to lipids, proteins, and dna, leading to the generation of lipid peroxidation, damage of nuclear and mitochondrial dna, neuronal apoptosis, and neuroinflammatory response. |
2022-04-14 |
2023-08-13 |
Not clear |