| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gokul Sudhakaran, Pandurangan Prathap, Ajay Guru, B Haridevamuthu, Raghul Murugan, Bader O Almutairi, Mikhlid H Almutairi, Annie Juliet, Pushparathinam Gopinath, Jesu Arockiara. Reverse pharmacology of Nimbin-N2 attenuates alcoholic liver injury and promotes the hepatoprotective dual role of improving lipid metabolism and downregulating the levels of inflammatory cytokines in zebrafish larval model. Molecular and cellular biochemistry. 2022-05-16. PMID:35575874. |
n2 was subjected to admet screening in-silico, and it was observed n2's co-exposure decreased the ros, apoptosis, lipid peroxidation, and macrophage accumulation in the liver of larval zebrafish. |
2022-05-16 |
2023-08-13 |
zebrafish |
| Aziza Alshahrani, Hong Jiang, Pratik Thapa, Na Ding, Yanning Hao, Qiou We. Understanding the Role of the Peroxiredoxin Family in the Regulation of Ferroptosis in Colorectal Cancer. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35556603. |
cell death due to ferroptosis in these cells was demonstrated by the measurement of lipid peroxidation using the sensor bodipy 581/591 c11 and differentiated with other modes of cell death such as apoptosis, autophagy and necrosis by the combined application of various inhibitors. |
2022-05-13 |
2023-08-13 |
Not clear |
| Hichem Moulahoum, Faezeh Ghorbanizamani, Zineb Khiari, Mohamed Toumi, Yasmina Benazzoug, Kerem Tok, Suna Timur, Figen Zihniogl. Artemisia alleviates AGE-induced liver complications via MAPK and RAGE signaling pathways modulation: a combinatorial study. Molecular and cellular biochemistry. 2022-05-11. PMID:35543857. |
additionally, aha reduced inflammatory mediators (il-6, tnfα), oxidative stress markers (no, lpo), and apoptosis (caspase 3). |
2022-05-11 |
2023-08-13 |
Not clear |
| Hana Valenta, Sophie Dupré, Mouna Abdesselem, Tania Bizouarn, Laura Baciou, Oliver Nüsse, Ariane Deniset-Besseau, Marie Erar. Consequences of the constitutive NOX2 activity in living cells: Cytosol acidification, apoptosis, and localized lipid peroxidation. Biochimica et biophysica acta. Molecular cell research. 2022-04-30. PMID:35489654. |
consequences of the constitutive nox2 activity in living cells: cytosol acidification, apoptosis, and localized lipid peroxidation. |
2022-04-30 |
2023-08-13 |
Not clear |
| Lin Chen, Qin Ru, Qi Xiong, Jun Yang, Guodong Xu, Yuxiang W. Potential Effects of Nrf2 in Exercise Intervention of Neurotoxicity Caused by Methamphetamine Oxidative Stress. Oxidative medicine and cellular longevity. vol 2022. 2022-04-28. PMID:35480870. |
methamphetamine can cause oxidative stress-centered lipid peroxidation, endoplasmic reticulum stress, mitochondrial dysfunction, excitatory neurotoxicity, and neuroinflammation and ultimately lead to nerve cell apoptosis, abnormal glial cell activation, and dysfunction of blood-brain barrier. |
2022-04-28 |
2023-08-13 |
Not clear |
| Wenhui Song, Weiyao Zhang, Lizhou Yue, Weiying Li. Revealing the Effects of Endoplasmic Reticulum Stress on Ferroptosis by Two-Channel Real-Time Imaging of pH and Viscosity. Analytical chemistry. 2022-04-18. PMID:35435658. |
besides, different from apoptosis and necrosis, ferroptosis is the result of lipid peroxidation accumulation. |
2022-04-18 |
2023-08-13 |
Not clear |
| An-Guo Wu, Yuan-Yuan Yong, Yi-Ru Pan, Li Zhang, Jian-Ming Wu, Yue Zhang, Yong Tang, Jing Wei, Lu Yu, Betty Yuen-Kwan Law, Chong-Lin Yu, Jian Liu, Cai Lan, Ru-Xiang Xu, Xiao-Gang Zhou, Da-Lian Qi. Targeting Nrf2-Mediated Oxidative Stress Response in Traumatic Brain Injury: Therapeutic Perspectives of Phytochemicals. Oxidative medicine and cellular longevity. vol 2022. 2022-04-14. PMID:35419162. |
most importantly, excessive oxidative stress causes bbb disruption and brings injury to lipids, proteins, and dna, leading to the generation of lipid peroxidation, damage of nuclear and mitochondrial dna, neuronal apoptosis, and neuroinflammatory response. |
2022-04-14 |
2023-08-13 |
Not clear |
| Ramona D'Amico, Marika Cordaro, Roberta Fusco, Alessio Filippo Peritore, Tiziana Genovese, Enrico Gugliandolo, Rosalia Crupi, Giuseppina Mandalari, Daniela Caccamo, Salvatore Cuzzocrea, Rosanna Di Paola, Rosalba Siracusa, Daniela Impellizzer. Consumption of Cashew ( Nutrients. vol 14. issue 7. 2022-04-12. PMID:35406088. |
in hhcy rats, cashew nuts (100 mg/kg orally, daily) were able to counteract clinical biochemical changes, oxidative and nitrosative stress, reduced antioxidant enzyme levels, lipid peroxidation, proinflammatory cytokine release, histological tissue injuries, and apoptosis in the kidney, colon, and liver, possibly by the modulation of the antioxidant nuclear factor erythroid 2-related factor 2 nrf-2 and inflammatory nuclear factor nf-kb pathways. |
2022-04-12 |
2023-08-13 |
rat |
| Meenu Singh, Yeshvandra Verma, Suresh Vs Ran. Potential toxicity of nickel nano and microparticles on the reproductive system of female rats-a comparative time-dependent study. Toxicology and industrial health. 2022-03-30. PMID:35352587. |
ovaries removed from these rats were analyzed to study the effects of nickel bioaccumulation on synthesis of steroid hormones, lipid peroxidation, apoptosis, and oxidative stress. |
2022-03-30 |
2023-08-13 |
human |
| Dimitra C Bobori, Anastasia Dimitriadi, Konstantinos Feidantsis, Athina Samiotaki, Danai Fafouti, Ioannis Sampsonidis, Stavros Kalogiannis, Georgia Kastrinaki, Dimitra A Lambropoulou, George Z Kyzas, George Koumoundouros, Dimitrios N Bikiaris, Martha Kaloyiann. Differentiation in the expression of toxic effects of polyethylene-microplastics on two freshwater fish species: Size matters. The Science of the total environment. 2022-03-26. PMID:35337874. |
the penetration of pe-mps to fish and the induced oxidative stress triggered changes in lipid peroxidation, dna damage and ubiquitination and furthermore stimulated signal transduction pathways leading to autophagy and apoptosis. |
2022-03-26 |
2023-08-13 |
human |
| Siqi Zhao, Wubin Zheng, Chao Yu, Gaoxin Xu, Xinyi Zhang, Chao Pan, Yongheng Feng, Kunxing Yang, Jin Zhou, Yong M. The Role of Ferroptosis in the Treatment and Drug Resistance of Hepatocellular Carcinoma. Frontiers in cell and developmental biology. vol 10. 2022-03-21. PMID:35309918. |
ferroptosis is a new regulatory cell death mediated by iron-dependent lipid peroxidation, which is different from apoptosis and necrosis in morphology, pathophysiology and mechanism. |
2022-03-21 |
2023-08-13 |
Not clear |
| Philipp Heher, Massimo Ganassi, Adelheid Weidinger, Elise N Engquist, Johanna Pruller, Thuy Hang Nguyen, Alexandra Tassin, Anne-Emilie Declèves, Kamel Mamchaoui, Christopher R S Banerji, Johannes Grillari, Andrey V Kozlov, Peter S Zammi. Interplay between mitochondrial reactive oxygen species, oxidative stress and hypoxic adaptation in facioscapulohumeral muscular dystrophy: Metabolic stress as potential therapeutic target. Redox biology. vol 51. 2022-03-06. PMID:35248827. |
dux4 triggers mitochondrial membrane polarisation prior to oxidative stress generation and apoptosis through mitoros, and affects mitochondrial health through lipid peroxidation. |
2022-03-06 |
2023-08-13 |
Not clear |
| Naranjan S Dhalla, Vijayan Elimban, Monika Bartekova, Adriana Adameov. Involvement of Oxidative Stress in the Development of Subcellular Defects and Heart Disease. Biomedicines. vol 10. issue 2. 2022-02-25. PMID:35203602. |
it is now well known that oxidative stress promotes lipid peroxidation, protein oxidation, activation of proteases, fragmentation of dna and alteration in gene expression for producing myocardial cell damage, whereas its actions for the induction of fibrosis, necrosis and apoptosis are considered to result in the loss of cardiomyocytes in different types of heart disease. |
2022-02-25 |
2023-08-13 |
Not clear |
| Dianlong Ge, Xue Zou, Yajing Chu, Jijuan Zhou, Wei Xu, Yue Liu, Qiangling Zhang, Yan Lu, Lei Xia, Aiyue Li, Chaoqun Huang, Pei Wang, Chengyin Shen, Yannan Ch. Analysis of volatile organic compounds in exhaled breath after radiotherapy. Journal of Zhejiang University. Science. B. vol 23. issue 2. 2022-02-21. PMID:35187888. |
during treatment, high-energy x-rays can induce apoptosis; meanwhile, cell membranes are damaged due to lipid peroxidation, converting unsaturated fatty acids into volatile metabolites (losada-barreiro and bravo-díaz, 2017). |
2022-02-21 |
2023-08-13 |
Not clear |
| Monireh Golpour, Mina Alimohammadi, Farshad Sohbatzadeh, Sadegh Fattahi, Sander Bekeschus, Alireza Rafie. Cold atmospheric pressure plasma treatment combined with starvation increases autophagy and apoptosis in melanoma in vitro and in vivo. Experimental dermatology. 2022-02-19. PMID:35181947. |
in vitro, starvation+cap led to cell morphology changes, decreased metabolic activity, and increased lipid peroxidation accompanied by apoptosis and dna fragmentation in murine b16 melanoma cells but not murine non-malignant l929 fibroblasts. |
2022-02-19 |
2023-08-13 |
Not clear |
| Yi-Jen Hsueh, Yen-Ning Chen, Yu-Ting Tsao, Chao-Min Cheng, Wei-Chi Wu, Hung-Chi Che. The Pathomechanism, Antioxidant Biomarkers, and Treatment of Oxidative Stress-Related Eye Diseases. International journal of molecular sciences. vol 23. issue 3. 2022-02-15. PMID:35163178. |
we review the oxidative damage (e.g., lipid peroxidation, dna lesions, autophagy, and apoptosis) that occurs in different areas of the eye (e.g., cornea, anterior chamber, lens, retina, and optic nerve). |
2022-02-15 |
2023-08-13 |
Not clear |
| Ayaka Asakawa, Genji Kawade, Morito Kurata, Sho Fukuda, Iichiroh Onishi, Yuko Kinowaki, Sachiko Ishibashi, Masumi Ikeda, Shiori Watabe, Masashi Kobayashi, Hironori Ishibashi, Kenichi Okubo, Masanobu Kitagawa, Kouhei Yamamot. Stratification of lung squamous cell carcinoma based on ferroptosis regulators: Potential for new therapeutic strategies involving ferroptosis induction. Lung cancer (Amsterdam, Netherlands). vol 165. 2022-02-01. PMID:35101731. |
ferroptosis is a recently discovered nonapoptotic cell death caused by intracellular lipid peroxidation that can bring about effective cell death in cancer cells resistant to apoptosis. |
2022-02-01 |
2023-08-13 |
Not clear |
| Xiao Sun, Ping Sun, Dong Zhen, Xiangli Xu, Li Yang, Danni Fu, Chengxi Wei, Xiaofeng Niu, Jiawei Tian, Hairu L. Melatonin alleviates doxorubicin-induced mitochondrial oxidative damage and ferroptosis in cardiomyocytes by regulating YAP expression. Toxicology and applied pharmacology. 2022-01-30. PMID:35093381. |
the results showed that yap downregulation abolished the protective effects of mel including apoptosis, mitochondrial lipid peroxidation, and ferroptosis. |
2022-01-30 |
2023-08-13 |
rat |
| Sepideh Khaksar, Mohammadreza Bigdeli, Arash Samiee, Zahra Shirazi-Zan. Antioxidant and Anti-apoptotic Effects of Cannabidiol in Model of Ischemic Stroke in Rats. Brain research bulletin. 2022-01-15. PMID:35031355. |
cbd played the anti-apoptosis and anti-oxidant roles in cerebral ischemia by affecting the pathways of intrinsic apoptosis, endogenous antioxidant enzymes, and lipid peroxidation. |
2022-01-15 |
2023-08-13 |
rat |
| Giulia Greco, Michael Schnekenburger, Elena Catanzaro, Eleonora Turrini, Fabio Ferrini, Piero Sestili, Marc Diederich, Carmela Fimognar. Discovery of Sulforaphane as an Inducer of Ferroptosis in U-937 Leukemia Cells: Expanding Its Anticancer Potential. Cancers. vol 14. issue 1. 2022-01-11. PMID:35008240. |
at 25 μm, sfn induced caspase-dependent apoptosis and at 50 μm ferroptosis was induced through depletion of glutathione (gsh), decreased gsh peroxidase 4 protein expression, and lipid peroxidation. |
2022-01-11 |
2023-08-13 |
Not clear |