| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Qun Guan, Le-Le Zhou, Yu-Bin Don. Ferroptosis in cancer therapeutics: a materials chemistry perspective. Journal of materials chemistry. B. vol 9. issue 43. 2021-11-11. PMID:34505861. |
ferroptosis, distinct from apoptosis, is a regulated form of cell death caused by lipid peroxidation that has attracted extensive research interest since it was first defined in 2012. |
2021-11-11 |
2023-08-13 |
Not clear |
| Faiza Alam, Hareem Syed, Sofia Amjad, Mukhtiar Baig, Taseer Ahmed Khan, Rehana Rehma. Interplay between oxidative stress, SIRT1, reproductive and metabolic functions. Current research in physiology. vol 4. 2021-11-10. PMID:34746831. |
high levels of ros can cause damage to deoxyribo nucleic acid (dna) in the nucleus and mitochondria, lipid peroxidation, apoptosis, inactivation of enzymes, and oxidation of proteins in spermatozoa. |
2021-11-10 |
2023-08-13 |
Not clear |
| Dmitry V Zaretsky, Maria Zaretskai. Degradation Products of Amyloid Protein: Are They The Culprits? Current Alzheimer research. vol 17. issue 10. 2021-11-04. PMID:33272185. |
the activation of other mechanisms, such as apoptosis or lipid peroxidation, aggravates the toxicity, but it itself can result from the same initial point, that is, ion disturbance due to an increased permeability of membranes. |
2021-11-04 |
2023-08-13 |
Not clear |
| Anna Rita Fetoni, Fabiola Paciello, Diana Troian. Cisplatin chemotherapy and cochlear damage: otoprotective and chemosensitization properties of polyphenols. Antioxidants & redox signaling. 2021-11-03. PMID:34731023. |
recent advances: cisplatin ototoxicity results from several mechanisms, including: redox imbalance caused by reactive oxygen species (ros) production and lipid peroxidation, activation of inflammation, p53 and its downstream pathways that culminate in apoptosis. |
2021-11-03 |
2023-08-13 |
Not clear |
| Francesca Puca, Fei Yu, Caterina Bartolacci, Piergiorgio Pettazzoni, Alessandro Carugo, Emmet Huang-Hobbs, Jintan Liu, Ciro Zanca, Federica Carbone, Edoardo Del Poggetto, Joy Gumin, Pushan Dasgupta, Sahil Seth, Sanjana Srinivasan, Frederick F Lang, Erik P Sulman, Philip L Lorenzi, Lin Tan, Mengrou Shan, Zachary P Tolstyka, Maureen Kachman, Li Zhang, Sisi Gao, Angela K Deem, Giannicola Genovese, Pier Paolo Scaglioni, Costas A Lyssiotis, Andrea Viale, Giulio F Draett. Medium-Chain Acyl-CoA Dehydrogenase Protects Mitochondria from Lipid Peroxidation in Glioblastoma. Cancer discovery. vol 11. issue 11. 2021-11-02. PMID:34039636. |
beyond the expected energetics impairment, mcad depletion in primary gbm models induced an irreversible cascade of detrimental metabolic effects characterized by accumulation of unmetabolized mcfas, which induced lipid peroxidation and oxidative stress, irreversible mitochondrial damage, and apoptosis. |
2021-11-02 |
2023-08-13 |
Not clear |
| Alexandra V Avgustinovich, Olga V Bakina, Sergey G Afanas'ev, Olga V Cheremisina, Liudmila V Spirina, Alexey Y Dobrodeev, Michail Buldakov, Evgeny L Choynzono. Nanoparticles in Gastric Cancer Management. Current pharmaceutical design. vol 27. issue 21. 2021-10-22. PMID:33222664. |
these are accompanied by lipid peroxidation, apoptosis, and autophagic flux. |
2021-10-22 |
2023-08-13 |
Not clear |
| Cimen Gülben Olguner, Uğur Koca, Emel Altekin, Bekir Uğur Ergür, Seden Duru, Pelin Girgin, Aydin Taşdöğen, Kerim Gündüz, Seda Güzeldağ, Muhammed Akkuş, Serap Cilaker Micil. Ischemic preconditioning attenuates lipid peroxidation and apoptosis in the cecal ligation and puncture model of sepsis. Experimental and therapeutic medicine. vol 5. issue 6. 2021-10-21. PMID:23837035. |
ischemic preconditioning attenuates lipid peroxidation and apoptosis in the cecal ligation and puncture model of sepsis. |
2021-10-21 |
2023-08-12 |
rat |
| Cimen Gülben Olguner, Uğur Koca, Emel Altekin, Bekir Uğur Ergür, Seden Duru, Pelin Girgin, Aydin Taşdöğen, Kerim Gündüz, Seda Güzeldağ, Muhammed Akkuş, Serap Cilaker Micil. Ischemic preconditioning attenuates lipid peroxidation and apoptosis in the cecal ligation and puncture model of sepsis. Experimental and therapeutic medicine. vol 5. issue 6. 2021-10-21. PMID:23837035. |
evidence exists that lipid peroxidation and apoptosis may be responsible for the high mortality due to sepsis. |
2021-10-21 |
2023-08-12 |
rat |
| Cimen Gülben Olguner, Uğur Koca, Emel Altekin, Bekir Uğur Ergür, Seden Duru, Pelin Girgin, Aydin Taşdöğen, Kerim Gündüz, Seda Güzeldağ, Muhammed Akkuş, Serap Cilaker Micil. Ischemic preconditioning attenuates lipid peroxidation and apoptosis in the cecal ligation and puncture model of sepsis. Experimental and therapeutic medicine. vol 5. issue 6. 2021-10-21. PMID:23837035. |
ischemic preconditioning (ip) is a method for the protection of tissues and organs against ischemia/reperfusion injury by reducing reactive oxygen species levels, lipid peroxidation and apoptosis. |
2021-10-21 |
2023-08-12 |
rat |
| Cimen Gülben Olguner, Uğur Koca, Emel Altekin, Bekir Uğur Ergür, Seden Duru, Pelin Girgin, Aydin Taşdöğen, Kerim Gündüz, Seda Güzeldağ, Muhammed Akkuş, Serap Cilaker Micil. Ischemic preconditioning attenuates lipid peroxidation and apoptosis in the cecal ligation and puncture model of sepsis. Experimental and therapeutic medicine. vol 5. issue 6. 2021-10-21. PMID:23837035. |
in conclusion, ip inhibits lipid peroxidation and attenuates histological injury and apoptosis in the lung and kidney during sepsis. |
2021-10-21 |
2023-08-12 |
rat |
| Hui Shang, Xuena Jang, Lingyun Shi, Yifei M. Lycorine inhibits cell proliferation and induced oxidative stress-mediated apoptosis via regulation of the JAK/STAT3 signaling pathway in HT-3 cells. Journal of biochemical and molecular toxicology. vol 35. issue 10. 2021-10-15. PMID:34558146. |
the ht-3 cells were treated with various lycorine dosages and we analyzed cell growth, lipid peroxidation, antioxidants, mitochondrial membrane potential (ΔΨm), dna damage, apoptosis markers by different in vitro methodologies. |
2021-10-15 |
2023-08-13 |
human |
| Sayed Haidar Abbas Raza, Ayman H Abd El-Aziz, Sameh A Abdelnour, Ahmed A Easa, Mahmoud Alagawany, Mayada R Farag, Mohsen G Al-Mutary, Ahmed Elfadadny, Rajwali Khan, Guobo Quan, Gong Cheng, Linsen Za. The role of forskolin as a lipolytic stimulator during in vitro oocyte maturation and the in vitro embryo production of livestock. Reproduction in domestic animals = Zuchthygiene. 2021-10-15. PMID:34592022. |
lipid ingathering in the oocyte cytoplasm augments lipid peroxidation (lpo) and oxidative stress increases the apoptosis process, declines the viability after thawing, declines cytoskeleton actin filament injuries, lowers the blastocyst rates and reduces cryotolerance in the early stages of embryo development. |
2021-10-15 |
2023-08-13 |
Not clear |
| Hui-Xian Li, Jia Feng, Qian Liu, Bi-Qian Ou, Shi-Yin Lu, Yi M. PACAP-derived mutant peptide MPAPO protects trigeminal ganglion cell and the retina from hypoxic injury through anti-oxidative stress, anti-apoptosis, and promoting axon regeneration. Biochimica et biophysica acta. General subjects. vol 1865. issue 12. 2021-10-12. PMID:34597723. |
disordered retina was attenuated with mpapo eye drops, as well as hypoxia-induced apoptosis in the developing retina, increase in lpo, and decrease in gsh levels and sod activity of the retina. |
2021-10-12 |
2023-08-13 |
mouse |
| Neda Gholami, Abasalt Hosseinzadeh Colagar, Mohammad Hossein Sinkakarimi, Farshad Sohbatzade. In vivo assessment of APPJ discharge on the earthworm: coelomic TAC and MDA levels, cell death, and tissue regeneration. Environmental science and pollution research international. 2021-10-12. PMID:34637123. |
therefore, in this study, we exposed aporrectodea trapezoides and eisenia fetida earthworms to appj discharge (0-30 s) to evaluate the impacts on regeneration of missed segments, apoptosis, lipid peroxidation (lpo), catalase activity (cat), total antioxidant capacity (tac), total proteins, and protein profile. |
2021-10-12 |
2023-08-13 |
cat |
| Hanna Yuk, Md Abdullah, Do-Hyung Kim, Haeseung Lee, Seung-Jin Le. Necrostatin-1 Prevents Ferroptosis in a RIPK1- and IDO-Independent Manner in Hepatocellular Carcinoma. Antioxidants (Basel, Switzerland). vol 10. issue 9. 2021-10-01. PMID:34572979. |
ferroptosis is caused by the iron-mediated accumulation of lipid peroxidation, which is distinct from apoptosis and necroptosis. |
2021-10-01 |
2023-08-13 |
Not clear |
| Hemapriyadarshini Vadarevu, Ridhima Juneja, Zachary Lyles, Juan L Vivero-Escot. Light-Activated Protoporphyrin IX-Based Polysilsesquioxane Nanoparticles Induce Ferroptosis in Melanoma Cells. Nanomaterials (Basel, Switzerland). vol 11. issue 9. 2021-10-01. PMID:34578640. |
our data obtained from different assays that analyzed annexin v binding, glutathione peroxidase activity, and lipid peroxidation demonstrate that the cell death in pdt using ppix-psilq nps is regulated by apoptosis and ferroptosis. |
2021-10-01 |
2023-08-13 |
Not clear |
| Hong Li, Yaru Yin, Jing Liu, Binghui Lu, Huimin Wan, Luxun Yang, Weidong Wang, Rong L. Hydrogen-rich water attenuates the radiotoxicity induced by tritium exposure in vitro and in vivo. Journal of radiation research. vol 62. issue 1. 2021-09-28. PMID:33231266. |
in addition, the anti-oxidative properties of hrw could attenuate the increased intracellular ros (such as o2•-, •oh and onoo-), resulting in reversing the exhaustion of cellular endogenous antioxidants (reduced gsh and sod), decreasing lipid peroxidation (mda), relieving dna oxidative damage, and depressing cell apoptosis and cytotoxicity induced by hto exposure. |
2021-09-28 |
2023-08-13 |
mouse |
| Xin Chen, Xuan Li, Xiaodong Xu, Luxiao Li, Ningning Liang, Lili Zhang, Jingwen Lv, Yun-Cheng Wu, Huiyong Yi. Ferroptosis and cardiovascular disease: role of free radical-induced lipid peroxidation. Free radical research. vol 55. issue 4. 2021-09-24. PMID:33455488. |
lpo products are involved in immune responses and cell deaths in this process, in which previous evidence supports the role of programmed cell death (apoptosis) and necrosis. |
2021-09-24 |
2023-08-13 |
Not clear |
| Yajuan Ni, Jie Deng, Xin Liu, Qing Li, Juanli Zhang, Hongyuan Bai, Jingwen Zhan. Echinacoside reverses myocardial remodeling and improves heart function via regulating SIRT1/FOXO3a/MnSOD axis in HF rats induced by isoproterenol. Journal of cellular and molecular medicine. vol 25. issue 1. 2021-09-15. PMID:33314649. |
here, we firstly induce cellular model of oxidative stress by iso with ac-16 cells and pre-treat with ech, the level of mitochondrial ros, mtdna oxidative injury, mmp, carbonylated protein, lipid peroxidation, intracellular ros and apoptosis are detected, confirm the effect of ech in mitochondrial oxidative stress and function in vitro. |
2021-09-15 |
2023-08-13 |
rat |
| Narjes Shahsavani, Arsalan Alizadeh, Hardeep Kataria, Soheila Karimi-Abdolrezae. Availability of neuregulin-1beta1 protects neurons in spinal cord injury and against glutamate toxicity through caspase dependent and independent mechanisms. Experimental neurology. vol 345. 2021-09-07. PMID:34314724. |
in the present study, using a clinically-relevant model of compressive/contusive sci in rats and an in vitro model of glutamate toxicity in primary neurons, we demonstrate nrg-1β1 provides early neuroprotection through attenuation of reactive oxygen species, lipid peroxidation, necrosis and apoptosis in acute and subacute stages of sci. |
2021-09-07 |
2023-08-13 |
rat |