Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Amany Abdel-Ghaffar, Ghada G Elhossary, Atef M Mahmoud, Amany H M Elshazly, Olfat A Hassanin, Anisa Saleh, Sahar M Mansour, Fatma G Metwally, Laila K Hanafy, Sawsan H Karam, Neveen Darweesh, Ahmed Mostafa At. Effects of 4-phenylbutyric acid on the development of diabetic retinopathy in diabetic rats: regulation of endoplasmic reticulum stress-oxidative activation. Archives of physiology and biochemistry. 2021-05-06. PMID:33653182. |
treatment of diabetic rats with 4-pba, increased the antioxidant capacity, reduced the levels of lipid peroxidation, organised the state of apoptosis and regulated the er stress - oxidative activation in retinal tissue. |
2021-05-06 |
2023-08-13 |
rat |
Yun Xu, Yongfang Jiang, Yi L. Pyrazinamide enhances lipid peroxidation and antioxidant levels to induce liver injury in rat models through PI3k/Akt inhibition. Toxicology research. vol 9. issue 3. 2021-04-29. PMID:32670546. |
we further verified that pi3k/akt signaling in response to 740y-p could attenuate hepatic injury, lipid peroxidation and apoptosis in rat liver cells in response to pza. |
2021-04-29 |
2023-08-13 |
rat |
b' Mehmet \\xc5\\x9eahin Ad\\xc4\\xb1yaman, \\xc3\\x96zlem Aba Ad\\xc4\\xb1yaman, Adile Ferda Da\\xc4\\x9fl\\xc4\\xb1, Mehmet Z\\xc3\\xbclkif Karahan, \\xc4\\xb0lyas Kaya, Mustafa Necati Da\\xc4\\x9fl\\xc4\\xb. Effects of grapeseed extract on doxorubicin-induced cardiotoxicity in rats. Herz. vol 46. issue Suppl 1. 2021-04-15. PMID:31970462.' |
proanthocyanidins found in grapeseed (gs) extract may inhibit chemically induced lipid peroxidation and apoptosis caused by oxidative stress. |
2021-04-15 |
2023-08-13 |
rat |
Alka Rani, Khem Chand Saini, Felix Bast, Sanjeet Mehariya, Shashi Kant Bhatia, Roberto Lavecchia, Antonio Zuorr. Microorganisms: A Potential Source of Bioactive Molecules for Antioxidant Applications. Molecules (Basel, Switzerland). vol 26. issue 4. 2021-04-07. PMID:33672774. |
oxidative stress originates from an elevated intracellular level of free oxygen radicals that cause lipid peroxidation, protein denaturation, dna hydroxylation, and apoptosis, ultimately impairing cell viability. |
2021-04-07 |
2023-08-13 |
Not clear |
Abouzar Najafi, Hossein Daghigh Kia, Mahdieh Mehdipour, Hamed Hamishehkar, Manuel Álvarez-Rodrígue. Effect of quercetin loaded liposomes or nanostructured lipid carrier (NLC) on post-thawed sperm quality and fertility of rooster sperm. Theriogenology. vol 152. 2021-03-29. PMID:32402991. |
sperm motility, viability, abnormalities, membrane integrity, mitochondrial activity, apoptosis status, lipid peroxidation (lp), gpx, sod, tac and fertility and hatchability rate were investigated after freeze-thawing. |
2021-03-29 |
2023-08-13 |
chicken |
Jie Yang, Wen-Wen Mu, Yu-Xin Cao, Guo-Yun Li. Synthesis and biological evaluation of β-ionone oriented proapoptosis agents by enhancing the ROS generation. Bioorganic chemistry. vol 104. 2021-03-29. PMID:32956875. |
importantly, the cytotoxicity of the β-ionone derivatives (1a, 1d and 1g) were relationship with their reactive oxygen species (ros)-generation abilities, which could lead to the redox imbalance, lipid peroxidation, the loss of mitochondrial membrane potential (mmp), the activation of bax and caspase 3, followed by cell apoptosis. |
2021-03-29 |
2023-08-13 |
Not clear |
Hao Zhang, Yanan Chen, Yueping Chen, Peilu Jia, Shuli Ji, Jianxiong Xu, Yue Li, Tian Wan. Comparison of the effects of resveratrol and its derivative pterostilbene on hepatic oxidative stress and mitochondrial dysfunction in piglets challenged with diquat. Food & function. vol 11. issue 5. 2021-03-24. PMID:32352466. |
administration of pt was more effective than its parent compound in inhibiting the dq-induced hepatic apoptosis and the increased generation of total cholesterol, superoxide anion, and lipid peroxidation products (p < 0.05). |
2021-03-24 |
2023-08-13 |
Not clear |
Rita Hargitai, Dávid Kis, Eszter Persa, Tünde Szatmári, Géza Sáfrány, Katalin Lumniczk. Oxidative Stress and Gene Expression Modifications Mediated by Extracellular Vesicles: An In Vivo Study of the Radiation-Induced Bystander Effect. Antioxidants (Basel, Switzerland). vol 10. issue 2. 2021-03-16. PMID:33494540. |
in bystander mice, no significant alterations were observed in lipid peroxidation or in the expression of genes connected to cell cycle arrest, senescence and apoptosis. |
2021-03-16 |
2023-08-13 |
mouse |
Karla Chavira-Ramos, Mario Orozco-Morales, Çimen Karasu, Alexey A Tinkov, Michael Aschner, Abel Santamaría, Ana Laura Colín-Gonzále. URB597 Prevents the Short-Term Excitotoxic Cell Damage in Rat Cortical Slices: Role of Cannabinoid 1 Receptors. Neurotoxicity research. vol 39. issue 2. 2021-03-10. PMID:33141426. |
urb597 prevented the quin-induced loss of mitochondrial function/cell viability and lipid peroxidation, while reduced necrosis, and to a lesser extent, apoptosis. |
2021-03-10 |
2023-08-13 |
rat |
Shahenda Mahgoub, Anas O Sallam, Hazem K A Sarhan, Amal A A Ammar, Sameh H Soro. Role of Diosmin in protection against the oxidative stress induced damage by gamma-radiation in Wistar albino rats. Regulatory toxicology and pharmacology : RTP. vol 113. 2021-02-23. PMID:32087353. |
results indicated that radiation-induced decline in the levels of antioxidant parameters (sod and gsh), increased lipid peroxidation, dna damage and apoptosis were improved by pre-administration of diosmin. |
2021-02-23 |
2023-08-13 |
rat |
Omar Cruz-Santiago, Iván Nelinho Pérez-Maldonado, Donaji Josefina González-Mille, Guillermo Espinosa-Reyes, Ángeles Martínez-Toledo, César Arturo Ilizaliturri-Hernánde. Nondestructive biomarkers in giant toad (Rhinella marina) to assess the effect of complex mixture of pollutants in Coatzacoalcos River, Mexico. Environmental toxicology and pharmacology. vol 82. 2021-02-22. PMID:33307127. |
in the blood samples, we determined the activity of enzymes, lipid peroxidation, and the presence of cell death (apoptosis). |
2021-02-22 |
2023-08-13 |
Not clear |
Yanyong Xu, Xiaoli Pan, Shuwei Hu, Yingdong Zhu, Fathima Cassim Bawa, Yuanyuan Li, Liya Yin, Yanqiao Zhan. Hepatocyte-specific expression of human carboxylesterase 2 attenuates nonalcoholic steatohepatitis in mice. American journal of physiology. Gastrointestinal and liver physiology. vol 320. issue 2. 2021-02-22. PMID:33325808. |
furthermore, human ces2 overexpression improved mitochondrial respiration and glycolytic function, and inhibited gluconeogenesis, lipid peroxidation, apoptosis, and inflammation. |
2021-02-22 |
2023-08-13 |
mouse |
Nastaran Injinari, Zeinab Amini-Farsani, Mahtab Yadollahi-Farsani, Hossein Teimor. Apoptotic effects of valproic acid on miR-34a, miR-520h and HDAC1 gene in breast cancer. Life sciences. vol 269. 2021-02-16. PMID:33453248. |
in the in vitro study, vpa led to apoptosis induction and increased lipid peroxidation products in breast cancer cells. |
2021-02-16 |
2023-08-13 |
Not clear |
Jamal Valipour, Sina Mojaverrostami, Beheshteh Abouhamzeh, Masoumeh Abdollah. Protective effects of hesperetin on the quality of sperm, apoptosis, lipid peroxidation, and oxidative stress during the process of cryopreservation: An experimental study. International journal of reproductive biomedicine. vol 19. issue 1. 2021-02-10. PMID:33554001. |
protective effects of hesperetin on the quality of sperm, apoptosis, lipid peroxidation, and oxidative stress during the process of cryopreservation: an experimental study. |
2021-02-10 |
2023-08-13 |
Not clear |
Ana Paula Vargas Visentin, Rafael Colombo, Ellen Scotton, Débora Soligo Fracasso, Adriane Ribeiro da Rosa, Catia Santos Branco, Mirian Salvado. Targeting Inflammatory-Mitochondrial Response in Major Depression: Current Evidence and Further Challenges. Oxidative medicine and cellular longevity. vol 2020. 2021-02-04. PMID:32351669. |
nevertheless, the effects of ros on the brain are well known, including lipid peroxidation of neuronal membranes, accumulation of peroxidation products in neurons, protein and dna damage, reduced antioxidant defenses, apoptosis induction, and neuroinflammation. |
2021-02-04 |
2023-08-13 |
Not clear |
Gonca Alak, Fatma Betül Özgeriş, Aslı Çilingir Yeltekin, Veysel Parlak, Arzu Ucar, Ozge Caglar, Hasan Turkez, Muhammed Atamanal. Hematological and Hepatic Effects of Ulexite in Zebrafish. Environmental toxicology and pharmacology. vol 80. 2021-02-03. PMID:32947019. |
the blood and liver tissues were taken at the end of the trial period then micronucleus (mn) rates, oxidative dna damage (8-ohdg), apoptosis (caspase-3), superoxide dismutase (sod), catalase (cat), glutathione peroxidase (gpx), myeloperoxidase (mpo), paraoxonase (pon), arylesterase (ar) and lipid peroxidation (mda) levels were determined. |
2021-02-03 |
2023-08-13 |
cat |
Sabiha Fatima, Raheek Alwaznah, Ghadeer S Aljuraiban, Samina Wasi, Manal Abudawood, Mahmoud Abulmeaty, Mohamed Y Berika, Feda S Aljase. Effect of seminal redox status on lipid peroxidation, apoptosis and DNA fragmentation in spermatozoa of infertile Saudi males. Saudi medical journal. vol 41. issue 3. 2021-01-20. PMID:32114595. |
effect of seminal redox status on lipid peroxidation, apoptosis and dna fragmentation in spermatozoa of infertile saudi males. |
2021-01-20 |
2023-08-13 |
Not clear |
Sabiha Fatima, Raheek Alwaznah, Ghadeer S Aljuraiban, Samina Wasi, Manal Abudawood, Mahmoud Abulmeaty, Mohamed Y Berika, Feda S Aljase. Effect of seminal redox status on lipid peroxidation, apoptosis and DNA fragmentation in spermatozoa of infertile Saudi males. Saudi medical journal. vol 41. issue 3. 2021-01-20. PMID:32114595. |
to assess the effect of seminal redox status on lipid peroxidation (lpo), apoptosis and integrity of sperm dna in infertile males. methods: in this case-control study, the total antioxidant status (tas) and reactive oxygen species (ros) levels were analyzed within the seminal plasma of fertile normozoospermic, n=40 and infertile (asthenozoospermic, n=30; oligoasthenoteratozoospermic, n=30) males. |
2021-01-20 |
2023-08-13 |
Not clear |
Hikmet Memmedov, Latife Merve Oktay, Burak Durmaz, Nur Selvi Günel, Hatice Kalkan Yı Ldırım, Eser Yıldırım Sözme. Propolis prevents inhibition of apoptosis by potassium bromate in CCD 841 human colon cell. Cell biochemistry and function. vol 38. issue 4. 2021-01-05. PMID:31990996. |
the antioxidant activity (antioxidant enzymes, lipid peroxidation) and apoptosis markers (caspase 3,8,9, cytochrome-c, tumour necrosis factor-related apoptosis-inducing ligand-r1 and r2 [trail], and apoptosis protease activating factor-1 [apaf-1] levels) were determined in ccd 841-human colon cell line after induction of oxidative stress by potassium bromate. |
2021-01-05 |
2023-08-13 |
human |
Hikmet Memmedov, Latife Merve Oktay, Burak Durmaz, Nur Selvi Günel, Hatice Kalkan Yı Ldırım, Eser Yıldırım Sözme. Propolis prevents inhibition of apoptosis by potassium bromate in CCD 841 human colon cell. Cell biochemistry and function. vol 38. issue 4. 2021-01-05. PMID:31990996. |
significance of the study: this study is the first investigation that shows protective effect of propolis against potassium bromate toxicity by means of decreasing lipid peroxidation and reversing the main molecule levels in intrinsic and extrinsic pathway of apoptosis. |
2021-01-05 |
2023-08-13 |
human |