| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xing Li, Jiheng Zhan, Yu Hou, Shudong Chen, Yonghui Hou, Zhifeng Xiao, Dan Luo, Dingkun Li. Coenzyme Q10 suppresses oxidative stress and apoptosis via activating the Nrf-2/NQO-1 and NF-κB signaling pathway after spinal cord injury in rats. American journal of translational research. vol 11. issue 10. 2020-10-01. PMID:31737205. |
therefore, we designed experiments to measure the changes in antioxidant capacity (glutathione (gsh), superoxide dismutase (sod) and the end product of lipid peroxidation (mda)) and apoptosis products (bax, bcl-2 and caspase-3) to evaluate the protective effects of coq10 on sci and investigated whether coq10 exerts its functions through the nrf-2/nqo-1 and nf-κb signaling pathway. |
2020-10-01 |
2023-08-13 |
rat |
| Rosita A Condorelli, Sandro La Vignera, Filippo Giacone, Linda Iacoviello, Laura M Mongioì, Giovanni Li Volti, Ignazio Barbagallo, Roberto Avola, Aldo E Caloger. Nicotine Effects and Receptor Expression on Human Spermatozoa: Possible Neuroendocrine Mechanism. Frontiers in physiology. vol 8. 2020-09-30. PMID:28400736. |
spermatozoa were incubated with nic 100 ng/ml and the nachr antagonist, hexamethonium (hex) (0, 100, 1,000, 10,000 ng/ml) for 3 and 24 h. the following sperm parameters evaluated: (a) progressive motility; (b) mitochondrial membrane potential (mmp); (c) chromatin compactness; (d) externalization of phosphatidylserine (ps); (e) late apoptosis; (f) viability; (g) dna fragmentation; (h) degree of lipid peroxidation (lp) by flow cytometry; (i) nachr subunits expression by quantitative real time pcr and (j) protein expression evaluation by western blot analysis. |
2020-09-30 |
2023-08-13 |
human |
| Jaya Kumar, Seong Lin Teoh, Srijit Das, Pasuk Mahakknaukrau. Oxidative Stress in Oral Diseases: Understanding Its Relation with Other Systemic Diseases. Frontiers in physiology. vol 8. 2020-09-30. PMID:28959211. |
this is due to lipid peroxidation and irreversible protein modification that leads to cellular apoptosis or programmed cell death. |
2020-09-30 |
2023-08-13 |
Not clear |
| Jayshree Nellore, Nandita . Paraquat exposure induces behavioral deficits in larval zebrafish during the window of dopamine neurogenesis. Toxicology reports. vol 2. 2020-09-30. PMID:28962434. |
wide arrays of biomarkers have been employed to delineate the toxic responses which include lipid peroxidation, glutathione (gsh) and apoptosis studies. |
2020-09-30 |
2023-08-13 |
human |
| Jayshree Nellore, Nandita . Paraquat exposure induces behavioral deficits in larval zebrafish during the window of dopamine neurogenesis. Toxicology reports. vol 2. 2020-09-30. PMID:28962434. |
a decrease in the gsh levels, increase in lipid peroxidation and apoptosis, respectively, were observed at various developmental stages. |
2020-09-30 |
2023-08-13 |
human |
| Rania Abdel Rahman Elgawish, Haidy G Abdel Rahman, Heba M A Abdelraze. Green tea extract attenuates CCl4-induced hepatic injury in male hamsters via inhibition of lipid peroxidation and p53-mediated apoptosis. Toxicology reports. vol 2. 2020-09-30. PMID:28962456. |
green tea extract attenuates ccl4-induced hepatic injury in male hamsters via inhibition of lipid peroxidation and p53-mediated apoptosis. |
2020-09-30 |
2023-08-13 |
Not clear |
| Sayed Masoud Hosseini, Elahe Taghiabadi, Khalil Abnous, Alireza Timcheh Hariri, Hamed Pourbakhsh, Hossein Hosseinzade. Protective effect of thymoquinone, the active constituent of Iranian journal of basic medical sciences. vol 20. issue 8. 2020-09-30. PMID:29085585. |
ethanol induces its noxious effects through reactive oxygen species production, and lipid peroxidation and apoptosis induction in different tissues and cell types. |
2020-09-30 |
2023-08-13 |
Not clear |
| Somayeh Kouhestani, Adele Jafari, Parvin Babae. Kaempferol attenuates cognitive deficit Neural regeneration research. vol 13. issue 10. 2020-09-30. PMID:30136699. |
the present study investigated the effects of kaempferol (kmp) isolated from the extract of mespilus germanica l. (medlar) leaves on cognitive impairment, hippocampal antioxidants, apoptosis, lipid peroxidation and neuro-inflammation markers in ovariectomized (ovx) rat models of sporadic ad. |
2020-09-30 |
2023-08-13 |
rat |
| Naruemon Wikan, Jiraporn Tocharus, Sivanan Sivasinprasasn, Aphisek Kongkaew, Waraluck Chaichompoo, Apichart Suksamrarn, Chainarong Tocharu. Capsaicinoid nonivamide improves nonalcoholic fatty liver disease in rats fed a high-fat diet. Journal of pharmacological sciences. vol 143. issue 3. 2020-09-30. PMID:32414691. |
hfd-induced hepatic steatosis was associated with significantly increased morphological disorganization, injury markers, oxidative stress, lipid peroxidation, and apoptosis. |
2020-09-30 |
2023-08-13 |
rat |
| Zhonglin Wu, Yuanyuan Zhang, Tao Song, Qiongtao Song, Ying Zhang, Xuan Zhang, Xue Han, Jianping Zhang, Li Ch. Magnesium isoglycyrrhizinate ameliorates doxorubicin-induced acute cardiac and hepatic toxicity via anti-oxidant and anti-apoptotic mechanisms in mice. Experimental and therapeutic medicine. vol 15. issue 1. 2020-09-29. PMID:29399108. |
these results demonstrate that inhibiting lipid peroxidation and reducing myocardial and hepatocyte apoptosis may be one of the mechanisms by which mgig exhibits hepatoprotective and cardioprotective effects in dox-treated mice. |
2020-09-29 |
2023-08-13 |
mouse |
| Luyao Xu, Benson O A Botchway, Songou Zhang, Jingying Zhou, Xuehong Li. Inhibition of NF-κB Signaling Pathway by Resveratrol Improves Spinal Cord Injury. Frontiers in neuroscience. vol 12. 2020-09-29. PMID:30337851. |
nf-κb signaling pathway plays a significant role in the pathophysiological mechanisms of sci including increase in inflammation, augmentation of damage caused by free radicals and lipid peroxidation as well as facilitation of apoptosis and axonal demyelination. |
2020-09-29 |
2023-08-13 |
Not clear |
| Mahyar Dorrigiv, Armin Zareiyan, Hossein Hosseinzade. Garlic (Allium sativum) as an antidote or a protective agent against natural or chemical toxicities: A comprehensive update review. Phytotherapy research : PTR. vol 34. issue 8. 2020-09-29. PMID:32068926. |
it has been shown that garlic and its major components can ameliorate the toxicity of different agents in brain, kidney, blood, liver, embryo, spleen, pancreas, heart, reproductive system in part through radical scavenging, antioxidant effect, reducing lipid peroxidation, anti-inflammatory, chelating agent, cytoprotective activities, increase protein synthesis in damaged tissues, suppressing apoptosis, modulation of p53, phosphoinositide 3-kinase, akt, nuclear factor (erythroid-derived 2)-like 2, antioxidant responsive element, p38 mapk, inducible nitric oxide synthase, cyclooxygenase-2, cytosolic phospholipases a2, cleaved-caspase-9, cleaved-caspase-3 bcl-2, bcl-2-associated x, peroxisome proliferator-activated receptor gamma, nf-jb, nuclear factor-kappab signaling pathways and cytochrome p450 enzymes. |
2020-09-29 |
2023-08-13 |
Not clear |
| Gadah I Al-Bashe. Green tea activity and iron overload induced molecular fibrogenesis of rat liver. Saudi journal of biological sciences. vol 26. issue 3. 2020-09-28. PMID:30899168. |
thereafter, we studied the effects of agte on iron overload-induced lipid peroxidation, anti-oxidant depletion, liver cell injury and apoptosis. |
2020-09-28 |
2023-08-13 |
rat |
| Bahareh Sadat Yousefsani, Nasim Akbarizadeh, Jalal Pourahma. The antioxidant and neuroprotective effects of Zolpidem on acrylamide-induced neurotoxicity using Wistar rat primary neuronal cortical culture. Toxicology reports. vol 7. 2020-09-28. PMID:32025499. |
thereafter, different neural toxicity endpoints caused by acrylamide including ros formation, lipid peroxidation, mitochondrial membrane potential collapse, lysosomal membrane integrity, and apoptosis were determined. |
2020-09-28 |
2023-08-13 |
rat |
| Michal Pardo, Itzhak Katra, James J Schaeur, Yinon Rudic. Mitochondria-mediated oxidative stress induced by desert dust in rat alveolar macrophages. GeoHealth. vol 1. issue 1. 2020-09-28. PMID:32158977. |
the dust samples induced cell death through apoptosis, mitochondrial dysfunction, and increased mitochondrial lipid peroxidation. |
2020-09-28 |
2023-08-13 |
rat |
| Liquan Wu, Xiaoxing Xiong, Xiaomin Wu, Yingze Ye, Zhihong Jian, Zeng Zhi, Lijuan G. Targeting Oxidative Stress and Inflammation to Prevent Ischemia-Reperfusion Injury. Frontiers in molecular neuroscience. vol 13. 2020-09-28. PMID:32194375. |
during reperfusion especially, superoxide anion free radicals, hydroxyl free radicals, and nitric oxide (no) are produced, which can cause lipid peroxidation, inflammation and cell apoptosis. |
2020-09-28 |
2023-08-13 |
Not clear |
| Zhongjie Yu, Qi Li, Jing Wang, Yali Yu, Yin Wang, Qihui Zhou, Peifeng L. Reactive Oxygen Species-Related Nanoparticle Toxicity in the Biomedical Field. Nanoscale research letters. vol 15. issue 1. 2020-09-28. PMID:32436107. |
due to the strong oxidation potential, the excess ros induced by nanoparticles can result in the damage of biomolecules and organelle structures and lead to protein oxidative carbonylation, lipid peroxidation, dna/rna breakage, and membrane structure destruction, which further cause necrosis, apoptosis, or even mutagenesis. |
2020-09-28 |
2023-08-13 |
Not clear |
| Xu She, Bin Lan, Haomei Tian, Biao Tan. Cross Talk Between Ferroptosis and Cerebral Ischemia. Frontiers in neuroscience. vol 14. 2020-09-28. PMID:32848555. |
distinct from apoptosis and necrosis, ferroptosis is evoked by iron-dependent lipid peroxidation. |
2020-09-28 |
2023-08-13 |
Not clear |
| Minlin Jiang, Meng Qiao, Chuanliang Zhao, Juan Deng, Xuefei Li, Caicun Zho. Targeting ferroptosis for cancer therapy: exploring novel strategies from its mechanisms and role in cancers. Translational lung cancer research. vol 9. issue 4. 2020-09-28. PMID:32953528. |
unlike apoptosis and autophagy, this new rcd is an iron-dependent cell death with features of lethal accumulation of reactive oxygen species (ros) and over production of lipid peroxidation. |
2020-09-28 |
2023-08-13 |
Not clear |
| Hongjing Zhao, Yu Wang, Menghao Guo, Mengyao Mu, Hongxian Yu, Mingwei Xin. Grass carps co-exposed to environmentally relevant concentrations of cypermethrin and sulfamethoxazole bear immunodeficiency and are vulnerable to subsequent Aeromonas hydrophila infection. Environmental pollution (Barking, Essex : 1987). vol 266. issue Pt 3. 2020-09-15. PMID:32663629. |
cmn or/and smz exposure led to oxidative damage (consumption of antioxidant enzymes (superoxide dismutase and catalase)) and lipid peroxidation (accumulation of malondialdehyde), induced apoptosis (increases in tunel index, bax/bcl-2, p53, puma and caspase family expression). |
2020-09-15 |
2023-08-13 |
human |