| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Randa Sghaier, Thomas Nury, Valerio Leoni, Claudio Caccia, Jean-Paul Pais De Barros, Ameur Cherif, Anne Vejux, Thibault Moreau, Khalifa Limem, Mohammad Samadi, John J Mackrill, Ahmed Slaheddine Masmoudi, Gérard Lizard, Amira Zarrou. Dimethyl fumarate and monomethyl fumarate attenuate oxidative stress and mitochondrial alterations leading to oxiapoptophagy in 158N murine oligodendrocytes treated with 7β-hydroxycholesterol. The Journal of steroid biochemistry and molecular biology. vol 194. 2020-01-14. PMID:31344443. |
oxidative stress and mitochondrial dysfunction contribute to the pathogenesis of neurodegenerative diseases and favor lipid peroxidation, leading to increased levels of 7β-hydroxycholesterol (7β-ohc) which induces oxiapoptophagy (oxidative stress, apoptosis, autophagy). |
2020-01-14 |
2023-08-13 |
cat |
| Vincenzo Migliaccio, Raffaella Sica, Rosaria Scudiero, Palma Simoniello, Rosalba Putti, Lillà Lionett. Physiological Adaptation to Simultaneous Chronic Exposure to High-Fat Diet and Dichlorodipheniletylhene (DDE) in Cells. vol 8. issue 5. 2020-01-06. PMID:31083466. |
d group showed a reduction in antioxidant capacity, and increases in lipid peroxidation, apoptosis, and proliferation associated with morphological impairment. |
2020-01-06 |
2023-08-13 |
rat |
| Vincenzo Migliaccio, Raffaella Sica, Rosaria Scudiero, Palma Simoniello, Rosalba Putti, Lillà Lionett. Physiological Adaptation to Simultaneous Chronic Exposure to High-Fat Diet and Dichlorodipheniletylhene (DDE) in Cells. vol 8. issue 5. 2020-01-06. PMID:31083466. |
dde-treated groups exhibited higher lipid peroxidation levels compared to n and d, associated with pronounced defect in antioxidant capacity, apoptosis, cellular proliferation, as well as with tissue damage. |
2020-01-06 |
2023-08-13 |
rat |
| Muhammad Ikram, Kamran Saeed, Amjad Khan, Tahir Muhammad, Muhammad Sohail Khan, Min Gi Jo, Shafiq Ur Rehman, Myeong Ok Ki. Natural Dietary Supplementation of Curcumin Protects Mice Brains against Ethanol-Induced Oxidative Stress-Mediated Neurodegeneration and Memory Impairment via Nrf2/TLR4/RAGE Signaling. Nutrients. vol 11. issue 5. 2020-01-06. PMID:31096703. |
according to our findings, ethanol triggered reactive oxygen species (ros), apoptosis, neuroinflammation, and memory impairment, which were significantly inhibited with the administration of curcumin, as assessed by ros, lipid peroxidation (lpo), and nrf2/ho-1 (nuclear factor erythroid 2-related factor 2/heme-oxygenase-1) expression in the experimental mice brains. |
2020-01-06 |
2023-08-13 |
mouse |
| A M Anuriev, V I Gorbache. [Hypoxic-ischemic brain damage in premature newborns]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 119. issue 8. Vyp. 2. 2020-01-03. PMID:31825364. |
at the same time, more careful consideration is given to the glutathione system, which protects against lipid peroxidation, the glutamate-calcium cascade, and the excitotoxicity mediated by it, as well as the processes of necrosis and apoptosis of nerve cells. |
2020-01-03 |
2023-08-13 |
Not clear |
| Zeynep Banu Doğanlar, Metehan Uzun, Mehmet Akif Ovali, Ayten Dogan, Gulin Ongoren, Oğuzhan Doğanla. Melatonin attenuates caspase-dependent apoptosis in the thoracic aorta by regulating element balance and oxidative stress in pinealectomised rats. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme. vol 44. issue 2. 2019-12-27. PMID:30058356. |
the results showed that melatonin deficiency led to an imbalance in essential element levels, unfolded or misfolded proteins, increased lipid peroxidation, and selectively induced caspase-dependent apoptosis in ta tissues without significantly affecting the bcl-2/bax ratio (2.28 in pinealectomised rats, 2.73 in pinealectomised rats treated with melatonin). |
2019-12-27 |
2023-08-13 |
rat |
| Elena Grasselli, Francesca Baldini, Giulia Vecchione, Paulo J Oliveira, Vilma A Sardão, Adriana Voci, Piero Portincasa, Laura Vergan. Excess fructose and fatty acids trigger a model of non‑alcoholic fatty liver disease progression in vitro: Protective effect of the flavonoid silybin. International journal of molecular medicine. vol 44. issue 2. 2019-12-23. PMID:31173180. |
cell viability, apoptosis, free radical production, lipid content, lipid peroxidation and activity of lipogenic enzymes were assessed by spectrophotometric assays. |
2019-12-23 |
2023-08-13 |
Not clear |
| C P Teixeira, R Florencio-Silva, G R S Sasso, A A F Carbonel, R S Simões, M J Simõe. Soy isoflavones protect against oxidative stress and diminish apoptosis in ovary of middle-aged female rats. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. vol 35. issue 7. 2019-12-20. PMID:30784335. |
after 8 weeks, rats were euthanized and their ovaries removed for histomorphometric (% follicles) and apoptosis (cleaved-caspase-3/bcl2 immunostaining) evaluations, or subjected to biochemical assays to survey reactive oxygen species (ros) and lipid peroxidation levels and total antioxidant capacity (tac). |
2019-12-20 |
2023-08-13 |
rat |
| Ahmad H Alhowail, Jenna Bloemer, Mohammed Majrashi, Priyanka D Pinky, Subhrajit Bhattacharya, Zhang Yongli, Dwipayan Bhattacharya, Matthew Eggert, Lauren Woodie, Manal A Buabeid, Nathaniel Johnson, Alyssa Broadwater, Bruce Smith, Muralikrishnan Dhanasekaran, Robert D Arnold, Vishnu Suppiramania. Doxorubicin-induced neurotoxicity is associated with acute alterations in synaptic plasticity, apoptosis, and lipid peroxidation. Toxicology mechanisms and methods. vol 29. issue 6. 2019-12-18. PMID:31010378. |
doxorubicin-induced neurotoxicity is associated with acute alterations in synaptic plasticity, apoptosis, and lipid peroxidation. |
2019-12-18 |
2023-08-13 |
Not clear |
| Ahmad H Alhowail, Jenna Bloemer, Mohammed Majrashi, Priyanka D Pinky, Subhrajit Bhattacharya, Zhang Yongli, Dwipayan Bhattacharya, Matthew Eggert, Lauren Woodie, Manal A Buabeid, Nathaniel Johnson, Alyssa Broadwater, Bruce Smith, Muralikrishnan Dhanasekaran, Robert D Arnold, Vishnu Suppiramania. Doxorubicin-induced neurotoxicity is associated with acute alterations in synaptic plasticity, apoptosis, and lipid peroxidation. Toxicology mechanisms and methods. vol 29. issue 6. 2019-12-18. PMID:31010378. |
this data indicates that acute dox exposure dose-dependently impairs synaptic processes associated with hippocampal neurotransmission, induces apoptosis, and increases lipid peroxidation leading to neurotoxicity. |
2019-12-18 |
2023-08-13 |
Not clear |
| Orathai Tangvarasittichai, Surapon Tangvarasitticha. Oxidative Stress, Ocular Disease and Diabetes Retinopathy. Current pharmaceutical design. vol 24. issue 40. 2019-12-17. PMID:30644339. |
oxidative stress is caused by free radicals or oxidant productions, including lipid peroxidation, protein modification, dna damage and apoptosis or cell death and results in cellular degeneration and neurodegeneration from damage to macromolecules. |
2019-12-17 |
2023-08-13 |
Not clear |
| Stefka Valcheva-Kuzmanova, Petko Denev, Miroslav Eftimov, Antoaneta Georgieva, Vasilena Kuzmanova, Atanas Kuzmanov, Krasimir Kuzmanov, Maria Tzanev. Protective effects of Aronia melanocarpa juices either alone or combined with extracts from Rosa canina or Alchemilla vulgaris in a rat model of indomethacin-induced gastric ulcers. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 132. 2019-12-13. PMID:31374297. |
the pretreatment with the juices reduced the severity of indomethacin-induced gastric lesions and antagonized the effects of indomethacin on apoptosis and lipid peroxidation. |
2019-12-13 |
2023-08-13 |
rat |
| Surendra Kumar, Dharmendra Kumar Yadav, Eun-Ha Choi, Mi-Hyun Ki. Insight from Molecular dynamic simulation of reactive oxygen species in oxidized skin membrane. Scientific reports. vol 8. issue 1. 2019-12-02. PMID:30185881. |
the insights from the simulations indicate that lipid peroxidation might perturb the membrane barrier, thereby inflicting oxidative stress that leads to apoptosis. |
2019-12-02 |
2023-08-13 |
Not clear |
| Georg Baue. Nitric Oxide's Contribution to Selective Apoptosis Induction in Malignant Cells through Multiple Reaction Steps. Critical reviews in oncogenesis. vol 21. issue 5-6. 2019-11-20. PMID:29431084. |
membrane-associated proton pumps ensure the protonation of peroxynitrite, followed by decomposition into no2 and hydroxyl radicals that cause lipid peroxidation and thus trigger the mitochondrial pathway of apoptosis. |
2019-11-20 |
2023-08-13 |
Not clear |
| Daniel M Evans, Jack Hughes, Leigh F Jones, Patrick J Murphy, Halina Falfushynska, Oksana Horyn, Inna M Sokolova, Jeppe Christensen, Simon J Coles, Piotr Rzymsk. Elucidating cylindrospermopsin toxicity via synthetic analogues: An in vitro approach. Chemosphere. vol 234. 2019-11-12. PMID:31207420. |
however, the greatest increase in lpo and increase in caspase-3 activity, an apoptosis marker, was demonstrated by an analogue containing guanidine, hydroxyl and uracil functionalities similar to those found in cyn but lacking the complex tricyclic structure of cyn. |
2019-11-12 |
2023-08-13 |
Not clear |
| Xiao-Jie Mi, Jin-Gang Hou, Zi Wang, Ye Han, Shen Ren, Jun-Nan Hu, Chen Chen, Wei L. The protective effects of maltol on cisplatin-induced nephrotoxicity through the AMPK-mediated PI3K/Akt and p53 signaling pathways. Scientific reports. vol 8. issue 1. 2019-10-25. PMID:30374107. |
besides, maltol pretreatment decreased oxidative stress, lipid peroxidation and apoptosis in cisplatin-treated mice. |
2019-10-25 |
2023-08-13 |
mouse |
| Chun-Fang Liu, Jing-Xuan Zhang, Yi-Qun Li, Chun Li, Xuan-Xuan Zhu, Ke-Xin Jia, Jin-Xia Wang, Jing-Xia Wang, Yuan-Fang Fan, Ying Xu, Ting Wang, Na Li. [Effects of Tripterygium Glycosides Tablets from 6 different manufacturers on acute liver injury of normal mice]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 44. issue 16. 2019-10-21. PMID:31602914. |
tripgerygium glycosides tablets from 6 manufacturers all resulted in liver function damage and liver histopathological changes,especially in jiangsu,hubei and fujian,and the mechanism may related to inhibit nrf2/ho-1 oxidative stress pathway and activate bax/bcl-2 apoptosis pathway to mediate lipid peroxidation and induce liver cell apoptosis. |
2019-10-21 |
2023-08-13 |
mouse |
| Wen-Xi He, Cheng-Liang Zhang, Dong Xiang, Jin-Yu Yang, Yan-Jiao Xu, Xiu-Hua Ren, Dong Li. [Mechanism of Calculus Bovis Sativus in inhibiting hepatocyte lipid deposition based on serum pharmacology]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 44. issue 17. 2019-10-21. PMID:31602953. |
the effects of cbs-containing serum on lipid peroxidation and hepatocytes apoptosis were evaluated by reactive oxygen species( ros) and apoptosis assay,respectively. |
2019-10-21 |
2023-08-13 |
mouse |
| Chong-Yang Li, Ya-Han Zhao, Hai-Sheng Hao, Hao-Yu Wang, Jin-Ming Huang, Chang-Liang Yan, Wei-Hua Du, Yun-Wei Pang, Pei-Pei Zhang, Yan Liu, Hua-Bin Zhu, Xue-Ming Zha. Resveratrol significantly improves the fertilisation capacity of bovine sex-sorted semen by inhibiting apoptosis and lipid peroxidation. Scientific reports. vol 8. issue 1. 2019-10-15. PMID:29765076. |
resveratrol significantly improves the fertilisation capacity of bovine sex-sorted semen by inhibiting apoptosis and lipid peroxidation. |
2019-10-15 |
2023-08-13 |
cattle |
| Sunwoo Park, Whasun Lim, Wonsik Jeong, Fuller W Bazer, Dongho Lee, Gwonhwa Son. Sideroxylin (Callistemon lanceolatus) suppressed cell proliferation and increased apoptosis in ovarian cancer cells accompanied by mitochondrial dysfunction, the generation of reactive oxygen species, and an increase of lipid peroxidation. Journal of cellular physiology. vol 233. issue 11. 2019-09-25. PMID:29904922. |
sideroxylin (callistemon lanceolatus) suppressed cell proliferation and increased apoptosis in ovarian cancer cells accompanied by mitochondrial dysfunction, the generation of reactive oxygen species, and an increase of lipid peroxidation. |
2019-09-25 |
2023-08-13 |
Not clear |