| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Javed Ahsan Quadri, Saba Sarwar, Pinky, Parmita Kar, Seema Singh, Saumya Ranjan Mallick, Sudheer Arava, Tapash Chand Nag, Tara Sankar Roy, A Sharif. Fluoride induced tissue hypercalcemia, IL-17 mediated inflammation and apoptosis lead to cardiomyopathy: Ultrastructural and biochemical findings. Toxicology. vol 406-407. 2019-03-11. PMID:29800585. |
in the fluoride exposed groups, a significant (≤0.05) increase in levels of oxidative stress, lpo and apoptosis were observed. |
2019-03-11 |
2023-08-13 |
human |
| Kpobari W Nkpaa, Godspower I Onyes. Rutin attenuates neurobehavioral deficits, oxidative stress, neuro-inflammation and apoptosis in fluoride treated rats. Neuroscience letters. vol 682. 2019-03-11. PMID:29908257. |
moreover, rut attenuated the naf - induced inhibition of antioxidant enzymes and ache activity and inhibits lipid peroxidation, neuro-inflammation and apoptosis in the cerebrum and striatum of the rats. |
2019-03-11 |
2023-08-13 |
rat |
| Kpobari W Nkpaa, Godspower I Onyes. Rutin attenuates neurobehavioral deficits, oxidative stress, neuro-inflammation and apoptosis in fluoride treated rats. Neuroscience letters. vol 682. 2019-03-11. PMID:29908257. |
collectively, the present study demonstrated that rut attenuates naf - induced toxicity in the cerebrum and striatum of rats via mechanisms involving enhancement of ache activity, antioxidant status with concomitant inhibition of lipid peroxidation, neuro-inflammation and apoptosis in rats. |
2019-03-11 |
2023-08-13 |
rat |
| Sara Damiano, Serena Montagnaro, Maria V Puzio, Lorella Severino, Ugo Pagnini, Marcella Barbarino, Daniele Cesari, Antonio Giordano, Salvatore Florio, Roberto Ciarci. Effects of antioxidants on apoptosis induced by dasatinib and nilotinib in K562 cells. Journal of cellular biochemistry. vol 119. issue 6. 2019-02-27. PMID:29345355. |
in this study, we wanted to test the ability of some antioxidants such resveratrol (res) or a new recombinant mitochondrial manganese containing superoxide dismutase (rmnsod) or δ-tocotrienol (δ-toco) to interact with das and nil on viability, reactive oxygen species (ros) production, lipid peroxidation, and apoptosis. |
2019-02-27 |
2023-08-13 |
Not clear |
| Caitlin W Brown, John J Amante, Arthur M Mercuri. Cell clustering mediated by the adhesion protein PVRL4 is necessary for α6β4 integrin-promoted ferroptosis resistance in matrix-detached cells. The Journal of biological chemistry. vol 293. issue 33. 2019-02-15. PMID:29934307. |
when the clustering was inhibited, single cells did not exhibit a significant increase in lipid peroxidation in the absence of α6β4, and they were more susceptible to apoptosis than to ferroptosis. |
2019-02-15 |
2023-08-13 |
Not clear |
| Reza Masoudi, Mohsen Sharafi, Ahmad Zare Shahneh, Hamid Kohram, Elahe Nejati-Amiri, Hamideh Karimi, Mahdi Khodaei-Motlagh, Abdolhossein Shahverd. Supplementation of extender with coenzyme Q10 improves the function and fertility potential of rooster spermatozoa after cryopreservation. Animal reproduction science. vol 198. 2019-02-08. PMID:30297204. |
the viability and apoptosis status, dna fragmentation, abnormal morphology, motion parameters, membrane functionality, mitochondrial activity, acrosome integrity, lipid peroxidation, and fertility potential were evaluated after the freeze-thaw process. |
2019-02-08 |
2023-08-13 |
chicken |
| G Morris, A J Walker, M Berk, M Maes, B K Pur. Cell Death Pathways: a Novel Therapeutic Approach for Neuroscientists. Molecular neurobiology. vol 55. issue 7. 2019-02-04. PMID:29052145. |
in the first part, the following mechanisms involved in different forms of cell death are considered, with a view to identifying potential therapeutic targets: tumour necrosis factor receptors (tnfrs) and their engagement by tumour necrosis factor-alpha (tnf-α); poly [adp-ribose] polymerase (parp)-1 cleavage; the apoptosis signalling kinase (ask)-c-jun n-terminal kinase (jnk) axis; lysosomal permeability; activation of programmed necrotic cell death; oxidative stress, caspase-3 inhibition and parthanatos; activation of inflammasomes by reactive oxygen species and the development of pyroptosis; oxidative stress, calcium dyshomeostasis and iron in the development of lysosomal-mediated necrosis and lysosomal membrane permeability; and oxidative stress, lipid peroxidation, iron dyshomeostasis and ferroptosis. |
2019-02-04 |
2023-08-13 |
Not clear |
| G K Vladimirov, A S Vikulina, D Volodkin, Yu A Vladimiro. Structure of the complex of cytochrome c with cardiolipin in non-polar environment. Chemistry and physics of lipids. vol 214. 2019-01-22. PMID:29856995. |
the complex of mitochondrial protein cytochrome c (cytc) with anionic phospholipid cardiolipin (cl) plays a crucial role in the initiation of apoptosis by catalyzing lipid peroxidation in mitochondrial membranes. |
2019-01-22 |
2023-08-13 |
Not clear |
| G K Vladimirov, A S Vikulina, D Volodkin, Yu A Vladimiro. Structure of the complex of cytochrome c with cardiolipin in non-polar environment. Chemistry and physics of lipids. vol 214. 2019-01-22. PMID:29856995. |
biochemistry (mosc) 78, 1086-1097) that nanospheres of cyt-cl complex, embedded into the lipid phase of mitochondrial membrane, catalyze lipid peroxidation, thereby initiating apoptosis. |
2019-01-22 |
2023-08-13 |
Not clear |
| Kamila Środa-Pomianek, Krystyna Michalak, Piotr Świątek, Andrzej Poła, Anna Palko-Łabuz, Olga Wesołowsk. Increased lipid peroxidation, apoptosis and selective cytotoxicity in colon cancer cell line LoVo and its doxorubicin-resistant subline LoVo/Dx in the presence of newly synthesized phenothiazine derivatives. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 106. 2018-12-18. PMID:29990852. |
increased lipid peroxidation, apoptosis and selective cytotoxicity in colon cancer cell line lovo and its doxorubicin-resistant subline lovo/dx in the presence of newly synthesized phenothiazine derivatives. |
2018-12-18 |
2023-08-13 |
human |
| Kamila Środa-Pomianek, Krystyna Michalak, Piotr Świątek, Andrzej Poła, Anna Palko-Łabuz, Olga Wesołowsk. Increased lipid peroxidation, apoptosis and selective cytotoxicity in colon cancer cell line LoVo and its doxorubicin-resistant subline LoVo/Dx in the presence of newly synthesized phenothiazine derivatives. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 106. 2018-12-18. PMID:29990852. |
in studied cancer cells cytotoxic effect of the phenothiazine derivatives was accompanied by apoptosis and autophagy induction as well as by the increase of cellular lipid peroxidation and intracellular reactive oxygen species generation. |
2018-12-18 |
2023-08-13 |
human |
| Cristina González-Ravina, Mercedes Aguirre-Lipperheide, Francisco Pinto, David Martín-Lozano, Manuel Fernández-Sánchez, Víctor Blasco, Esther Santamaría-López, Luz Candena. Effect of dietary supplementation with a highly pure and concentrated docosahexaenoic acid (DHA) supplement on human sperm function. Reproductive biology. vol 18. issue 3. 2018-12-11. PMID:29934046. |
we analyzed macroscopic and microscopic sperm parameters, oxidative stress, apoptosis, lipid peroxidation, mitochondrial membrane potential and dna fragmentation before and after supplementation with different dha daily doses (0.5, 1 and 2 g) or placebo for 1 and 3 months. |
2018-12-11 |
2023-08-13 |
human |
| Liping Zhang, Lingyu Zhang, Lin Li, Christian Hölsche. Neuroprotective effects of the novel GLP-1 long acting analogue semaglutide in the MPTP Parkinson's disease mouse model. Neuropeptides. vol 71. 2018-12-11. PMID:30017231. |
in addition, both glp-1 analogues rescued the decrease of tyrosine hydroxylase (th) levels, alleviated the inflammation response, reduced lipid peroxidation, inhibited the apoptosis pathway, and also increased autophagy- related protein expression, to protect dopaminergic neurons in the substantia nigra and striatum. |
2018-12-11 |
2023-08-13 |
mouse |
| b' Sandra E\\xc4\\x8dimovi\\xc4\\x87, Mirna Velki, Rosemary Vukovi\\xc4\\x87, Ivna \\xc5\\xa0tolfa \\xc4\\x8camagajevac, Anja Petek, Rebeka Bo\\xc5\\xa1njakovi\\xc4\\x87, Magdalena Grgi\\xc4\\x87, P\\xc3\\xa9ter Engelmann, Korn\\xc3\\xa9lia Bod\\xc3\\xb3, Vlatka Filipovi\\xc4\\x87-Mariji\\xc4\\x87, Du\\xc5\\xa1ica Ivankovi\\xc4\\x87, Marijana Erk, Tatjana Mijo\\xc5\\xa1ek, Zdenko Lon\\xc4\\x8dari\\xc4\\x8. Acute toxicity of selenate and selenite and their impacts on oxidative status, efflux pump activity, cellular and genetic parameters in earthworm Eisenia andrei. Chemosphere. vol 212. 2018-11-08. PMID:30145422.' |
namely, acute toxicity, apoptosis, efflux pump activity, different enzymatic and non-enzymatic biomarkers (acetylcholinesterase, carboxylesterase, glutathione s-transferase, catalase, glutathione reductase and superoxide dismutase activities, lipid peroxidation level and gsh/gssg ratio) and expression of genes involved in oxidative and immune response have been investigated. |
2018-11-08 |
2023-08-13 |
Not clear |
| V M Alifirova, A N Boiko, Ya V Vlasov, M V Davydovskaya, M N Zakharova, N A Malkova, E V Popova, S A Sivertseva, N N Spirin, N V Khachanova, Т Е Shmid. [Clinical guidelines for the use of dimethyl fumarate in relapsing-remitting multiple sclerosis]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 117. issue 1. 2018-10-31. PMID:28252608. |
activation and infiltration of immune cells in brain tissues, lipid peroxidation products, mitochondrial dysfunction, defective antioxidant protection, and many other pathological factors result in demyelination, axonal injury and death, and apoptosis of oligodendrocytes and neurons, all of which causes constant progression of the disease. |
2018-10-31 |
2023-08-13 |
Not clear |
| Sandra Aurora Niño, Guadalupe Martel-Gallegos, Adriana Castro-Zavala, Benita Ortega-Berlanga, Juan Manuel Delgado, Héctor Hernández-Mendoza, Elizabeth Romero-Guzmán, Judith Ríos-Lugo, Sergio Rosales-Mendoza, María E Jiménez-Capdeville, Sergio Zarazú. Chronic Arsenic Exposure Increases Aβ Chemical research in toxicology. vol 31. issue 1. 2018-10-31. PMID:29155576. |
at the cellular level, arsenic toxicity involves increased generation of reactive species that induce severe cellular alterations such as dna fragmentation, apoptosis, and lipid peroxidation. |
2018-10-31 |
2023-08-13 |
rat |
| Mohammad Moshahid Khan, Weng-Lang Yang, Max Brenner, Alexandra Cerutti Bolognese, Ping Wan. Cold-inducible RNA-binding protein (CIRP) causes sepsis-associated acute lung injury via induction of endoplasmic reticulum stress. Scientific reports. vol 7. 2018-10-22. PMID:28128330. |
effector pathways downstream from er stress - apoptosis, nf-κb (p65), proinflammatory cytokines (il-6, il-1β), neutrophil chemoattractants (mip-2, kc), neutrophil infiltration (mpo activity), lipid peroxidation (4-hne), and nitric oxide (inos) - were significantly increased in wt mice, but only mildly elevated in cirp ko mice. |
2018-10-22 |
2023-08-13 |
mouse |
| Min Wen, Lin Ding, Lingyu Zhang, Peixu Cong, Tiantian Zhang, Jie Xu, Yaoguang Chang, Yuming Wang, Changhu Xu. A comparative study of eicosapentaenoic acid enriched phosphatidylcholine and ethyl ester in improving cognitive deficiency in Alzheimer's disease model rats. Food & function. vol 9. issue 4. 2018-10-03. PMID:29541708. |
further research indicated that epa-pc and dha-ee could significantly decrease lipid peroxidation levels, alleviate mitochondria-dependent apoptosis, and inhibit the hyperphosphorylation of tau mediated by gsk3β. |
2018-10-03 |
2023-08-13 |
rat |
| Dan Sun, Yao Lu, Su-Juan Zhang, Kai-Ge Wang, Yuan L. The effect of ellagic acid on photodynamic therapy in leukemia cells. General physiology and biophysics. vol 37. issue 3. 2018-10-01. PMID:29938677. |
the results showed that ea supplementation alone did not affect the lipid peroxidation, dna damage and apoptosis in k562 cells. |
2018-10-01 |
2023-08-13 |
Not clear |
| Dan Sun, Yao Lu, Su-Juan Zhang, Kai-Ge Wang, Yuan L. The effect of ellagic acid on photodynamic therapy in leukemia cells. General physiology and biophysics. vol 37. issue 3. 2018-10-01. PMID:29938677. |
it increases the lipid peroxidation, dna damage, apoptosis and decreases the survival rate in k562 cells induced by ala-pdt. |
2018-10-01 |
2023-08-13 |
Not clear |