| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ahmad H Alhowail, Jenna Bloemer, Mohammed Majrashi, Priyanka D Pinky, Subhrajit Bhattacharya, Zhang Yongli, Dwipayan Bhattacharya, Matthew Eggert, Lauren Woodie, Manal A Buabeid, Nathaniel Johnson, Alyssa Broadwater, Bruce Smith, Muralikrishnan Dhanasekaran, Robert D Arnold, Vishnu Suppiramania. Doxorubicin-induced neurotoxicity is associated with acute alterations in synaptic plasticity, apoptosis, and lipid peroxidation. Toxicology mechanisms and methods. vol 29. issue 6. 2019-12-18. PMID:31010378. |
this data indicates that acute dox exposure dose-dependently impairs synaptic processes associated with hippocampal neurotransmission, induces apoptosis, and increases lipid peroxidation leading to neurotoxicity. |
2019-12-18 |
2023-08-13 |
Not clear |
| Orathai Tangvarasittichai, Surapon Tangvarasitticha. Oxidative Stress, Ocular Disease and Diabetes Retinopathy. Current pharmaceutical design. vol 24. issue 40. 2019-12-17. PMID:30644339. |
oxidative stress is caused by free radicals or oxidant productions, including lipid peroxidation, protein modification, dna damage and apoptosis or cell death and results in cellular degeneration and neurodegeneration from damage to macromolecules. |
2019-12-17 |
2023-08-13 |
Not clear |
| Stefka Valcheva-Kuzmanova, Petko Denev, Miroslav Eftimov, Antoaneta Georgieva, Vasilena Kuzmanova, Atanas Kuzmanov, Krasimir Kuzmanov, Maria Tzanev. Protective effects of Aronia melanocarpa juices either alone or combined with extracts from Rosa canina or Alchemilla vulgaris in a rat model of indomethacin-induced gastric ulcers. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 132. 2019-12-13. PMID:31374297. |
the pretreatment with the juices reduced the severity of indomethacin-induced gastric lesions and antagonized the effects of indomethacin on apoptosis and lipid peroxidation. |
2019-12-13 |
2023-08-13 |
rat |
| Surendra Kumar, Dharmendra Kumar Yadav, Eun-Ha Choi, Mi-Hyun Ki. Insight from Molecular dynamic simulation of reactive oxygen species in oxidized skin membrane. Scientific reports. vol 8. issue 1. 2019-12-02. PMID:30185881. |
the insights from the simulations indicate that lipid peroxidation might perturb the membrane barrier, thereby inflicting oxidative stress that leads to apoptosis. |
2019-12-02 |
2023-08-13 |
Not clear |
| Georg Baue. Nitric Oxide's Contribution to Selective Apoptosis Induction in Malignant Cells through Multiple Reaction Steps. Critical reviews in oncogenesis. vol 21. issue 5-6. 2019-11-20. PMID:29431084. |
membrane-associated proton pumps ensure the protonation of peroxynitrite, followed by decomposition into no2 and hydroxyl radicals that cause lipid peroxidation and thus trigger the mitochondrial pathway of apoptosis. |
2019-11-20 |
2023-08-13 |
Not clear |
| Daniel M Evans, Jack Hughes, Leigh F Jones, Patrick J Murphy, Halina Falfushynska, Oksana Horyn, Inna M Sokolova, Jeppe Christensen, Simon J Coles, Piotr Rzymsk. Elucidating cylindrospermopsin toxicity via synthetic analogues: An in vitro approach. Chemosphere. vol 234. 2019-11-12. PMID:31207420. |
however, the greatest increase in lpo and increase in caspase-3 activity, an apoptosis marker, was demonstrated by an analogue containing guanidine, hydroxyl and uracil functionalities similar to those found in cyn but lacking the complex tricyclic structure of cyn. |
2019-11-12 |
2023-08-13 |
Not clear |
| Xiao-Jie Mi, Jin-Gang Hou, Zi Wang, Ye Han, Shen Ren, Jun-Nan Hu, Chen Chen, Wei L. The protective effects of maltol on cisplatin-induced nephrotoxicity through the AMPK-mediated PI3K/Akt and p53 signaling pathways. Scientific reports. vol 8. issue 1. 2019-10-25. PMID:30374107. |
besides, maltol pretreatment decreased oxidative stress, lipid peroxidation and apoptosis in cisplatin-treated mice. |
2019-10-25 |
2023-08-13 |
mouse |
| Chun-Fang Liu, Jing-Xuan Zhang, Yi-Qun Li, Chun Li, Xuan-Xuan Zhu, Ke-Xin Jia, Jin-Xia Wang, Jing-Xia Wang, Yuan-Fang Fan, Ying Xu, Ting Wang, Na Li. [Effects of Tripterygium Glycosides Tablets from 6 different manufacturers on acute liver injury of normal mice]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 44. issue 16. 2019-10-21. PMID:31602914. |
tripgerygium glycosides tablets from 6 manufacturers all resulted in liver function damage and liver histopathological changes,especially in jiangsu,hubei and fujian,and the mechanism may related to inhibit nrf2/ho-1 oxidative stress pathway and activate bax/bcl-2 apoptosis pathway to mediate lipid peroxidation and induce liver cell apoptosis. |
2019-10-21 |
2023-08-13 |
mouse |
| Wen-Xi He, Cheng-Liang Zhang, Dong Xiang, Jin-Yu Yang, Yan-Jiao Xu, Xiu-Hua Ren, Dong Li. [Mechanism of Calculus Bovis Sativus in inhibiting hepatocyte lipid deposition based on serum pharmacology]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 44. issue 17. 2019-10-21. PMID:31602953. |
the effects of cbs-containing serum on lipid peroxidation and hepatocytes apoptosis were evaluated by reactive oxygen species( ros) and apoptosis assay,respectively. |
2019-10-21 |
2023-08-13 |
mouse |
| Chong-Yang Li, Ya-Han Zhao, Hai-Sheng Hao, Hao-Yu Wang, Jin-Ming Huang, Chang-Liang Yan, Wei-Hua Du, Yun-Wei Pang, Pei-Pei Zhang, Yan Liu, Hua-Bin Zhu, Xue-Ming Zha. Resveratrol significantly improves the fertilisation capacity of bovine sex-sorted semen by inhibiting apoptosis and lipid peroxidation. Scientific reports. vol 8. issue 1. 2019-10-15. PMID:29765076. |
resveratrol significantly improves the fertilisation capacity of bovine sex-sorted semen by inhibiting apoptosis and lipid peroxidation. |
2019-10-15 |
2023-08-13 |
cattle |
| Sunwoo Park, Whasun Lim, Wonsik Jeong, Fuller W Bazer, Dongho Lee, Gwonhwa Son. Sideroxylin (Callistemon lanceolatus) suppressed cell proliferation and increased apoptosis in ovarian cancer cells accompanied by mitochondrial dysfunction, the generation of reactive oxygen species, and an increase of lipid peroxidation. Journal of cellular physiology. vol 233. issue 11. 2019-09-25. PMID:29904922. |
sideroxylin (callistemon lanceolatus) suppressed cell proliferation and increased apoptosis in ovarian cancer cells accompanied by mitochondrial dysfunction, the generation of reactive oxygen species, and an increase of lipid peroxidation. |
2019-09-25 |
2023-08-13 |
Not clear |
| Sunwoo Park, Whasun Lim, Wonsik Jeong, Fuller W Bazer, Dongho Lee, Gwonhwa Son. Sideroxylin (Callistemon lanceolatus) suppressed cell proliferation and increased apoptosis in ovarian cancer cells accompanied by mitochondrial dysfunction, the generation of reactive oxygen species, and an increase of lipid peroxidation. Journal of cellular physiology. vol 233. issue 11. 2019-09-25. PMID:29904922. |
results of our study showed that sideroxylin decreased cell proliferation and increased apoptosis, causing dna fragmentation, depolarization of the mitochondrial membrane, the generation of reactive oxygen species, and an increase of lipid peroxidation in ovarian cancer cells (es2 and ov90 cells). |
2019-09-25 |
2023-08-13 |
Not clear |
| Wenhui Qiu, Ming Yang, Shuai Liu, Penghui Lei, Lei Hu, Bei Chen, Minghong Wu, Ke-Jian Wan. Toxic Effects of Bisphenol S Showing Immunomodulation in Fish Macrophages. Environmental science & technology. vol 52. issue 2. 2019-09-17. PMID:29261303. |
at a concentration of 100 μg/l, bps and bpa showed comparable pro-inflammatory potential with both up-regulating the production of free radicals and cytokine expression; however, bps had no significant potency with regards to inducing lipid peroxidation and apoptosis, different from bpa's effects. |
2019-09-17 |
2023-08-13 |
human |
| Youngshim Choi, Mohamed A Abdelmegeed, Byoung-Joon Son. Preventive effects of indole-3-carbinol against alcohol-induced liver injury in mice via antioxidant, anti-inflammatory, and anti-apoptotic mechanisms: Role of gut-liver-adipose tissue axis. The Journal of nutritional biochemistry. vol 55. 2019-09-17. PMID:29331880. |
daily treatment with i3c alleviated etoh-induced liver injury and hepatocyte apoptosis, but not steatosis, by attenuating elevated oxidative stress, as evidenced by the decreased levels of hepatic lipid peroxidation, hydrogen peroxide, cyp2e1, nadph-oxidase, and protein acetylation with maintenance of mitochondrial complex i, ii, and iii protein levels and activities. |
2019-09-17 |
2023-08-13 |
mouse |
| Kuan-Jen Bai, Kai-Jen Chuang, Chia-Ling Chen, Ming-Kai Jhan, Ta-Chih Hsiao, Tsun-Jen Cheng, Li-Te Chang, Ta-Yuan Chang, Hsiao-Chi Chuan. Microglial activation and inflammation caused by traffic-related particulate matter. Chemico-biological interactions. vol 311. 2019-09-16. PMID:31348917. |
we determined the cytotoxicity, oxidative stress, lipid peroxidation, inflammation, activation, autophagy, and apoptosis due to exposure to carbon black (cb) and diesel exhaust particles (deps) in bv2 microglial cells. |
2019-09-16 |
2023-08-13 |
rat |
| Wesam Kooti, Karo Servatyari, Masoud Behzadifar, Majid Asadi-Samani, Fatemeh Sadeghi, Bijan Nouri, Hadi Zare Marzoun. Effective Medicinal Plant in Cancer Treatment, Part 2: Review Study. Journal of evidence-based complementary & alternative medicine. vol 22. issue 4. 2019-08-16. PMID:28359161. |
enhancement p53 protein expression, reducing the expression of proteins p27, p21, nfκb expression and induction of apoptosis, inhibition of the pi3k/akt pathway, and reduction of the level of acid phosphatase and lipid peroxidation are the most effective mechanisms of herbal plants that can inhibit cell cycle and proliferation. |
2019-08-16 |
2023-08-13 |
Not clear |
| Cleetus Cherupanakkal, Daisy Mariya Samadanam, Krishna Raja Muthuraman, Surya Ramesh, Amrit Venkatesan, Agiesh Kumar Balakrishna Pillai, Soundravally Rajendira. Lipid peroxidation, DNA damage, and apoptosis in dengue fever. IUBMB life. vol 70. issue 11. 2019-08-14. PMID:30120880. |
lipid peroxidation, dna damage, and apoptosis in dengue fever. |
2019-08-14 |
2023-08-13 |
Not clear |
| B Bobrowska-Korczak, D Skrajnowska, A K Kiss, R Wrzesien, W Bielecki, A Orzoł, P Zebrowski, S Biale. Lipid peroxidation as a predictive biomarker of the early stage of cancer. Journal of biological regulators and homeostatic agents. vol 33. issue 3. 2019-08-08. PMID:31094165. |
no relationship was found between the process of lipid peroxidation due to the supplementation with selenium and copper, and the lower incidence of cancer and the induction of apoptosis. |
2019-08-08 |
2023-08-13 |
rat |
| Shuo-Shuo Yang, Cheng-Bing Yu, Zhen Luo, Wen-Li Luo, Jing Zhang, Jian-Xiong Xu, Wei-Na X. Berberine attenuates sodium palmitate-induced lipid accumulation, oxidative stress and apoptosis in grass carp(Ctenopharyngodon idella)hepatocyte in vitro. Fish & shellfish immunology. vol 88. 2019-07-25. PMID:30880233. |
then, the cell viability, intracellular triglyceride (tg) content, lipid peroxide (lpo), malonaldehyde (mda) content, cytochrome c, caspase-9, caspase-3 and apoptosis were detected. |
2019-07-25 |
2023-08-13 |
Not clear |
| Shuo-Shuo Yang, Cheng-Bing Yu, Zhen Luo, Wen-Li Luo, Jing Zhang, Jian-Xiong Xu, Wei-Na X. Berberine attenuates sodium palmitate-induced lipid accumulation, oxidative stress and apoptosis in grass carp(Ctenopharyngodon idella)hepatocyte in vitro. Fish & shellfish immunology. vol 88. 2019-07-25. PMID:30880233. |
sodium palmitate decreased cell viability and increased intracellular tg content, lipid droplet accumulation, lpo and mda concentrations, caused caspase-3 and caspase-9 activation, then led to apoptosis accompanied by cytochrome c release from mitochondria into the cytoplasm. |
2019-07-25 |
2023-08-13 |
Not clear |