| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T L de Jager, A E Cockrell, S S Du Plessi. Ultraviolet Light Induced Generation of Reactive Oxygen Species. Advances in experimental medicine and biology. vol 996. 2018-04-10. PMID:29124687. |
lipid peroxidation and dna fragmentation), apoptosis and cell death. |
2018-04-10 |
2023-08-13 |
human |
| M Tunçdemir, S P Ertürküner, D Özçeli. Investigation of lipid peroxidation and antiapoptotic effects of zinc aganist liver damage in diabetic rats. Human & experimental toxicology. vol 36. issue 8. 2018-04-09. PMID:27609014. |
in addition, we have investigated the role of zn supplementation on apoptosis, lipid peroxidation levels, and the distribution of metallothionein (mt) in diabetic liver tissue. |
2018-04-09 |
2023-08-13 |
rat |
| Ning Wang, Wen Jing Yi, Lu Tan, Jia Hui Zhang, Jiamin Xu, Yi Chen, Mengting Qin, Shuang Yu, Jing Guan, Rui Zhan. Apigenin attenuates streptozotocin-induced pancreatic β cell damage by its protective effects on cellular antioxidant defense. In vitro cellular & developmental biology. Animal. vol 53. issue 6. 2018-04-09. PMID:28181104. |
pretreatment with apigenin effectively decreased the intracellular reactive oxygen species (ros) production, attenuated cellular dna damage, diminished lipid peroxidation, relieved protein carbonylation, and restored the cell apoptosis of pancreatic beta cells stressed by stz. |
2018-04-09 |
2023-08-13 |
rat |
| Mengqing Xiao, Huiqin Zhong, Lin Xia, Yongzhen Tao, Huiyong Yi. Pathophysiology of mitochondrial lipid oxidation: Role of 4-hydroxynonenal (4-HNE) and other bioactive lipids in mitochondria. Free radical biology & medicine. vol 111. 2018-04-03. PMID:28456642. |
oxidation of the mitochondria-specific phospholipid cardiolipin and generation of bioactive lipids through mitochondrial lpo has been increasingly recognized as an important event orchestrating apoptosis, metabolic reprogramming of energy production, mitophagy, and immune responses. |
2018-04-03 |
2023-08-13 |
human |
| Yang Wang, Yanping Wu, Yuanyuan Wang, Han Xu, Xiaoqiang Mei, Dongyou Yu, Yibing Wang, Weifen L. Antioxidant Properties of Probiotic Bacteria. Nutrients. vol 9. issue 5. 2018-03-09. PMID:28534820. |
oxidative stress defines a condition in which the prooxidant-antioxidant balance in the cell is disturbed, resulting in dna hydroxylation, protein denaturation, lipid peroxidation, and apoptosis, ultimately compromising cells' viability. |
2018-03-09 |
2023-08-13 |
Not clear |
| Hui Zhao, Wei Meng, Yang Li, Wei Liu, Binsheng Fu, Yang Yang, Qi Zhang, Guihua Che. The protective effects of CHIR99021 against oxidative injury in LO2 cells. Die Pharmazie. vol 71. issue 11. 2018-03-08. PMID:29441966. |
the results showed that a cell oxidative injury model was established by treating lo2 cells with 200 μmol/l h2o2 for 6 h. cells exposed to h2o2 resulted in a significant decrease of cell viability and increase of cell apoptosis, which was accompanied by increasing ros levels, disruption of mitochondrial membrane potential, excessive lipid peroxidation, reduction of sod activity, and increased levels of alt and ast. |
2018-03-08 |
2023-08-13 |
Not clear |
| S K Shanuja, S Iswarya, A Gnanaman. Marine fungal DHICA as a UVB protectant: Assessment under in vitro and in vivo conditions. Journal of photochemistry and photobiology. B, Biology. vol 179. 2018-02-23. PMID:29367149. |
uvb protection studies under in vitro conditions emphasizes dhica significantly protect hacat cells from uvb exposure by quenching the generated ros, reducing cell apoptosis, maintain the cellular integrity and sequentially down regulating the lpo (lipid peroxidation) and up-regulating the antioxidant enzyme (sod (superoxide dismutase), catalase, gpx (glutathione peroxidase)) respectively. |
2018-02-23 |
2023-08-13 |
mouse |
| Mohammed I Y Elmallah, Manal F Elkhadragy, Ebtesam M Al-Olayan, Ahmed E Abdel Monei. Protective Effect of Fragaria ananassa Crude Extract on Cadmium-Induced Lipid Peroxidation, Antioxidant Enzymes Suppression, and Apoptosis in Rat Testes. International journal of molecular sciences. vol 18. issue 5. 2018-02-08. PMID:28475120. |
protective effect of fragaria ananassa crude extract on cadmium-induced lipid peroxidation, antioxidant enzymes suppression, and apoptosis in rat testes. |
2018-02-08 |
2023-08-13 |
human |
| Irena Baranowska-Bosiacka, Beata Bosiacka, Julita Rast, Izabela Gutowska, Jolanta Wolska, Ewa Rębacz-Maron, Kamila Dębia, Katarzyna Janda, Jan Korbecki, Dariusz Chlube. Macro- and Microelement Content and Other Properties of Chaenomeles japonica L. Fruit and Protective Effects of Its Aqueous Extract on Hepatocyte Metabolism. Biological trace element research. vol 178. issue 2. 2018-01-25. PMID:28101713. |
hence, the purpose of our study was to examine fresh japanese quince fruit in terms of (1) ascorbic acid, oxalate, fiber, macro- and micronutrients, dry matter, extract, total acidity, antioxidant activity, and phenolic compound levels; and (2) the effect of its extract on in vitro hepatocyte metabolism, measured by the concentration of lipid peroxides (lpo) and reactive oxygen species (ros) and the severity of apoptosis and necrosis. |
2018-01-25 |
2023-08-13 |
Not clear |
| Amit Kumar Chauhan, Namrata Mittra, Vinod Kumar, Devendra Kumar Patel, Chetna Sing. Inflammation and B-cell Lymphoma-2 Associated X Protein Regulate Zinc-Induced Apoptotic Degeneration of Rat Nigrostriatal Dopaminergic Neurons. Molecular neurobiology. vol 53. issue 8. 2018-01-22. PMID:26497033. |
on the contrary, zn augmented lipid peroxidation, activity of superoxide dismutase, expression of tnf-α, il-1β, bcl-xl, and p53-upregulated modulator of apoptosis (puma), and translocation of nf-κb and bax from the cytosol to the nucleus and mitochondria, respectively, with concomitant increase in the mitochondrial cytochrome c release and activation of procaspase-3 and -9. |
2018-01-22 |
2023-08-13 |
rat |
| Natarajan Suganthy, Dicson Sheeja Malar, Kasi Pandima Dev. Rhizophora mucronata attenuates beta-amyloid induced cognitive dysfunction, oxidative stress and cholinergic deficit in Alzheimer's disease animal model. Metabolic brain disease. vol 31. issue 4. 2018-01-12. PMID:27188290. |
furthermore, merm attenuated lipid peroxidation, protein oxidation, restored the antioxidant status and inhibited neuronal apoptosis by down-regulating the level of caspase 3 and bax protein. |
2018-01-12 |
2023-08-13 |
mouse |
| Elana R Elkin, Sean M Harris, Rita Loch-Carus. Trichloroethylene metabolite S-(1,2-dichlorovinyl)-l-cysteine induces lipid peroxidation-associated apoptosis via the intrinsic and extrinsic apoptosis pathways in a first-trimester placental cell line. Toxicology and applied pharmacology. vol 338. 2018-01-12. PMID:29129777. |
because elevated apoptosis and lipid peroxidation in placenta have been observed in pregnancy morbidities involving poor placentation, we evaluated the effects of dcvc exposure on apoptosis and lipid peroxidation in a human extravillous trophoblast cell line, htr-8/svneo. |
2018-01-12 |
2023-08-13 |
human |
| Elana R Elkin, Sean M Harris, Rita Loch-Carus. Trichloroethylene metabolite S-(1,2-dichlorovinyl)-l-cysteine induces lipid peroxidation-associated apoptosis via the intrinsic and extrinsic apoptosis pathways in a first-trimester placental cell line. Toxicology and applied pharmacology. vol 338. 2018-01-12. PMID:29129777. |
following exposure, we measured apoptosis using flow cytometry, caspase activity using luminescence assays, gene expression using qrt-pcr, and lipid peroxidation using a malondialdehyde quantification assay. |
2018-01-12 |
2023-08-13 |
human |
| Elana R Elkin, Sean M Harris, Rita Loch-Carus. Trichloroethylene metabolite S-(1,2-dichlorovinyl)-l-cysteine induces lipid peroxidation-associated apoptosis via the intrinsic and extrinsic apoptosis pathways in a first-trimester placental cell line. Toxicology and applied pharmacology. vol 338. 2018-01-12. PMID:29129777. |
co-treatment with the antioxidant peroxyl radical scavenger (±)-α-tocopherol attenuated caspase 3 and 7 activity, suggesting that lipid peroxidation mediates dcvc-induced apoptosis in extravillous trophoblasts. |
2018-01-12 |
2023-08-13 |
human |
| Elana R Elkin, Sean M Harris, Rita Loch-Carus. Trichloroethylene metabolite S-(1,2-dichlorovinyl)-l-cysteine induces lipid peroxidation-associated apoptosis via the intrinsic and extrinsic apoptosis pathways in a first-trimester placental cell line. Toxicology and applied pharmacology. vol 338. 2018-01-12. PMID:29129777. |
our findings suggest that dcvc-induced apoptosis and lipid peroxidation in extravillous trophoblasts could contribute to poor placentation if similar effects occur in vivo in response to tce exposure, indicating that further studies into this mechanism are warranted. |
2018-01-12 |
2023-08-13 |
human |
| Ershun Liang, Min Ma, Lei Wang, Xue Liu, Jinfeng Xu, Mingxiang Zhang, Ruixue Yang, Yuxia Zha. The BET/BRD inhibitor JQ1 attenuates diabetes-induced cognitive impairment in rats by targeting Nox4-Nrf2 redox imbalance. Biochemical and biophysical research communications. vol 495. issue 1. 2018-01-05. PMID:29113796. |
stz-induced diabetic rats exhibited obvious oxidative stress and apoptosis in the hippocampus assessed by augmentation of lipid peroxidation, positive tunel staining, elevated ratio of bax/bcl-2 and increased caspase 3 activity. |
2018-01-05 |
2023-08-13 |
rat |
| Lixia Chen, Huanbiao Mo, Ling Zhao, Weimin Gao, Shu Wang, Meghan M Cromie, Chuanwen Lu, Jia-Sheng Wang, Chwan-Li She. Therapeutic properties of green tea against environmental insults. The Journal of nutritional biochemistry. vol 40. 2017-12-29. PMID:27723473. |
formation of reactive radicals, lipid peroxidation, inflammation, genotoxicity, hepatotoxicity, embryotoxicity, neurological alterations, apoptosis, and carcinogenic events are some of the mechanisms mediating the toxic effects of the environmental toxins and toxicants. |
2017-12-29 |
2023-08-13 |
human |
| Marijana Sekulic-Jablanovic, Vesna Petkovic, Matthew B Wright, Krystsina Kucharava, Nathan Huerzeler, Soledad Levano, Yves Brand, Katharina Leitmeyer, Andrea Glutz, Alexander Bausch, Daniel Bodme. Effects of peroxisome proliferator activated receptors (PPAR)-γ and -α agonists on cochlear protection from oxidative stress. PloS one. vol 12. issue 11. 2017-12-26. PMID:29182629. |
gentamicin treatment induced production of reactive oxygen species (ros), lipid peroxidation, caspase activation, parp-1 cleavage, and hc apoptosis in cultured ocs. |
2017-12-26 |
2023-08-13 |
mouse |
| Shing-Hwa Liu, Cheng-Tien Wu, Kuo-How Huang, Ching-Chia Wang, Siao-Syun Guan, Li-Ping Chen, Chih-Kang Chian. C/EBP homologous protein (CHOP) deficiency ameliorates renal fibrosis in unilateral ureteral obstructive kidney disease. Oncotarget. vol 7. issue 16. 2017-12-14. PMID:26942460. |
chop deficiency could also ameliorate lipid peroxidation and endogenous antioxidant enzymes depletion, tubular apoptosis, and inflammatory cells infiltration in the uuo kidneys. |
2017-12-14 |
2023-08-13 |
mouse |
| Dan Sun, Yao Lu, Su-Juan Zhang, Kai-Ge Wang, Zhe Su. Research on the effect of formononetin on photodynamic therapy in K562 cells. General physiology and biophysics. vol 36. issue 4. 2017-11-24. PMID:28836497. |
the results showed that formononetin supplementation alone did not affect the lipid peroxidation, dna damage and apoptosis in k562 cells. |
2017-11-24 |
2023-08-13 |
Not clear |