| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y Ito, M Arakawa, K Ishige, H Fukud. Comparative study of survival signal withdrawal- and 4-hydroxynonenal-induced cell death in cerebellar granule cells. Neuroscience research. vol 35. issue 4. 2000-02-07. PMID:10617323. |
the lipid peroxidation product, 4-hydroxynonenal (hne), has been shown to induce apoptosis in pc12 cells and hippocampal neurons. |
2000-02-07 |
2023-08-12 |
Not clear |
| U N Da. Essential fatty acids, lipid peroxidation and apoptosis. Prostaglandins, leukotrienes, and essential fatty acids. vol 61. issue 3. 2000-02-04. PMID:10582655. |
essential fatty acids, lipid peroxidation and apoptosis. |
2000-02-04 |
2023-08-12 |
Not clear |
| U N Da. Essential fatty acids, lipid peroxidation and apoptosis. Prostaglandins, leukotrienes, and essential fatty acids. vol 61. issue 3. 2000-02-04. PMID:10582655. |
phosphorylation of bcl-2 inhibits its ability to interfere with apoptosis and enhances lipid peroxidation leading to the occurrence of apoptosis. |
2000-02-04 |
2023-08-12 |
Not clear |
| U N Da. Essential fatty acids, lipid peroxidation and apoptosis. Prostaglandins, leukotrienes, and essential fatty acids. vol 61. issue 3. 2000-02-04. PMID:10582655. |
based on these results, it is suggested that long-chain fatty acids induce apoptosis by enhancing lipid peroxidation, suppressing bcl-2 expression possibly by phosphorylation and augmentation of p450 activity. |
2000-02-04 |
2023-08-12 |
Not clear |
| H L Borges, R Linde. Gamma irradiation leads to two waves of apoptosis in distinct cell populations of the retina of newborn rats. Journal of cell science. vol 112 ( Pt 23). 2000-02-03. PMID:10564649. |
the antioxidant pyrrolidinedithiocarbamate prevented the early but not the late wave of apoptosis following irradiation, and blocked lipid peroxidation at 6 hours after the insult, suggesting that the two waves of apoptosis are indeed mediated by distinct mechanisms. |
2000-02-03 |
2023-08-12 |
rat |
| F Galli, S Rovidati, S Benedetti, F Canestrari, B Ferraro, A Floridi, U Buoncristian. Lipid peroxidation, leukocyte function and apoptosis in hemodialysis patients treated with vitamin E-modified filters. Contributions to nephrology. vol 127. 2000-01-28. PMID:10629785. |
lipid peroxidation, leukocyte function and apoptosis in hemodialysis patients treated with vitamin e-modified filters. |
2000-01-28 |
2023-08-12 |
Not clear |
| L C Park, N Y Calingasan, K Uchida, H Zhang, G E Gibso. Metabolic impairment elicits brain cell type-selective changes in oxidative stress and cell death in culture. Journal of neurochemistry. vol 74. issue 1. 2000-01-18. PMID:10617112. |
among the cell types tested, only in neurons did td induce apoptosis and cause the accumulation of 4-hydroxy-2-nonenal, a lipid peroxidation product. |
2000-01-18 |
2023-08-12 |
Not clear |
| S Camandola, G Poli, M P Mattso. The lipid peroxidation product 4-hydroxy-2,3-nonenal increases AP-1-binding activity through caspase activation in neurons. Journal of neurochemistry. vol 74. issue 1. 2000-01-18. PMID:10617117. |
the membrane lipid peroxidation product 4-hydroxy-2,3-nonenal (hne) is increasingly implicated in the disruption of neuronal calcium homeostasis that occurs in various paradigms of neuronal excitotoxicity and apoptosis. |
2000-01-18 |
2023-08-12 |
rat |
| S Camandola, G Poli, M P Mattso. The lipid peroxidation product 4-hydroxy-2,3-nonenal increases AP-1-binding activity through caspase activation in neurons. Journal of neurochemistry. vol 74. issue 1. 2000-01-18. PMID:10617117. |
the possible mechanistic links between lipid peroxidation and alterations in gene transcription during neuronal apoptosis have not previously been examined. |
2000-01-18 |
2023-08-12 |
rat |
| Z X Yao, K Drieu, L I Szweda, V Papadopoulo. Free radicals and lipid peroxidation do not mediate beta-amyloid-induced neuronal cell death. Brain research. vol 847. issue 2. 1999-12-21. PMID:10575089. |
abeta increased free radical production and lipid peroxidation in pc12 nerve cells, leading to increased 4-hydroxy-2-nonenal (hne) production and modification of specific mitochondrial target proteins, apoptosis and cell death. |
1999-12-21 |
2023-08-12 |
Not clear |
| Y Ma, T Ogino, T Kawabata, J Li, K Eguchi, S Okad. Cupric nitrilotriacetate-induced apoptosis in HL-60 cells association with lipid peroxidation, release of cytochrome C from mitochondria, and activation of caspase-3. Free radical biology & medicine. vol 27. issue 1-2. 1999-11-12. PMID:10443940. |
cupric nitrilotriacetate-induced apoptosis in hl-60 cells association with lipid peroxidation, release of cytochrome c from mitochondria, and activation of caspase-3. |
1999-11-12 |
2023-08-12 |
human |
| Y Ma, T Ogino, T Kawabata, J Li, K Eguchi, S Okad. Cupric nitrilotriacetate-induced apoptosis in HL-60 cells association with lipid peroxidation, release of cytochrome C from mitochondria, and activation of caspase-3. Free radical biology & medicine. vol 27. issue 1-2. 1999-11-12. PMID:10443940. |
these results suggested that cu-nta-induced apoptosis in hl-60 cells was, at least in part, triggered by free radical-induced lipid peroxidation of membrane, which induced the release of cytochrome c from mitochondria and activation of caspase-3. |
1999-11-12 |
2023-08-12 |
human |
| F Galli, F Canestrari, U Buoncristian. Biological effects of oxidant stress in haemodialysis: the possible roles of vitamin E. Blood purification. vol 17. issue 2-3. 1999-11-02. PMID:10449865. |
their rationale is based on the emerging role of vitamin e in counteracting some biological effects associated with oxidant stress namely lipid peroxidation and apoptosis. |
1999-11-02 |
2023-08-12 |
Not clear |
| S A Lund, J Murdoch, E A Van Kirk, W J Murdoc. Mitogenic and antioxidant mechanisms of estradiol action in preovulatory ovine follicles: relevance to luteal function. Biology of reproduction. vol 61. issue 2. 1999-08-31. PMID:10411516. |
acute suppression of estradiol production in proestrous ewes by an aromatase inhibitor (arimidex) was associated with follicular lipid peroxidation, testosterone accumulation, and a granulosa cell deficiency (decreased proliferation/increased apoptosis). |
1999-08-31 |
2023-08-12 |
Not clear |
| S L Chan, S P Tammariello, S Estus, M P Mattso. Prostate apoptosis response-4 mediates trophic factor withdrawal-induced apoptosis of hippocampal neurons: actions prior to mitochondrial dysfunction and caspase activation. Journal of neurochemistry. vol 73. issue 2. 1999-08-13. PMID:10428045. |
pretreatment of cultures with 17beta-estradiol, vitamin e, and uric acid largely prevented par-4 induction and cell death following tfw, demonstrating necessary roles for oxidative stress and membrane lipid peroxidation in tfw-induced neuronal apoptosis. |
1999-08-13 |
2023-08-12 |
rat |
| T Wei, C Chen, J Hou, B Zhao, W Xin, A Mor. The antioxidant EPC-K1 attenuates NO-induced mitochondrial dysfunction, lipid peroxidation and apoptosis in cerebellar granule cells. Toxicology. vol 134. issue 2-3. 1999-07-26. PMID:10403631. |
the antioxidant epc-k1 attenuates no-induced mitochondrial dysfunction, lipid peroxidation and apoptosis in cerebellar granule cells. |
1999-07-26 |
2023-08-12 |
Not clear |
| L K Weave. Carbon monoxide poisoning. Critical care clinics. vol 15. issue 2. 1999-07-01. PMID:10331130. |
additionally, various animal studies have demonstrated that co interferes with myoglobin, p450, and other enzyme function; causes lipid peroxidation through neutrophil activation; produces oxidative stress manifested by peroxynitrate deposition in endothelium; binds to cytochrome aa3, disrupting intracellular oxygen utilization; can cause neuroexcitotoxicity; and contributes to hippocampal cellular death through apoptosis. |
1999-07-01 |
2023-08-12 |
Not clear |
| A Barrientos, C T Morae. Titrating the effects of mitochondrial complex I impairment in the cell physiology. The Journal of biological chemistry. vol 274. issue 23. 1999-07-01. PMID:10347173. |
we observed a quantitative correlation between the level of ci impairment and cell respiration, cell growth, free radical production, lipid peroxidation, mitochondrial membrane potential, and apoptosis. |
1999-07-01 |
2023-08-12 |
human |
| D Wu, A I Cederbau. Ethanol-induced apoptosis to stable HepG2 cell lines expressing human cytochrome P-4502E1. Alcoholism, clinical and experimental research. vol 23. issue 1. 1999-06-01. PMID:10029205. |
the ethanol-induced apoptosis was prevented by 4-methylpyrazole, an inhibitor of ethanol oxidation by cyp2e1, and by trolox, an antioxidant that prevents lipid peroxidation. |
1999-06-01 |
2023-08-12 |
human |
| Y Higuchi, S Matsukaw. Glutathione depletion induces giant DNA and high-molecular-weight DNA fragmentation associated with apoptosis through lipid peroxidation and protein kinase C activation in C6 glioma cells. Archives of biochemistry and biophysics. vol 363. issue 1. 1999-04-22. PMID:10049497. |
glutathione depletion induces giant dna and high-molecular-weight dna fragmentation associated with apoptosis through lipid peroxidation and protein kinase c activation in c6 glioma cells. |
1999-04-22 |
2023-08-12 |
rat |